Stiffness estimation is crucial for delicate object manipulation in robotic and prosthetic hands but remains challenging due to dependence on force and displacement measurement and real-time sensory integration. This study presents a piezoelectric sensing framework for stiffness estimation at first contact during pinch grasps, addressing the limitations of traditional force-based methods. Inspired by human skin, a multimodal tactile sensor that captures vibrational and force data is developed and integrated into a prosthetic hand's fingertip. Machine learning models, including support vector machines and convolutional neural networks, demonstrate that vibrational signals within the critical 15 ms after first contact reliably encode stiffness, achieving classification accuracies up to 98.6% and regression errors as low as 2.39 Shore A on real-world objects of varying stiffness. Inference times of less than 1.5 ms are significantly faster than the average grasp closure time (16.65 ms in our dataset), enabling real-time stiffness estimation before the object is fully grasped. By leveraging the transient asymmetry in grasp dynamics, where one finger contacts the object before the others, this method enables early grasp modulation, enhancing safety and intuitiveness in prosthetic hands while offering broad applications in robotics.

Time Series Motif Discovery (TSMD), which aims at finding recurring patterns in time series, is an important task in numerous application domains, and many methods for this task exist. These methods are usually evaluated qualitatively. A few metrics for quantitative evaluation, where discovered motifs are compared to some ground truth, have been proposed, but they typically make implicit assumptions that limit their applicability. This paper introduces PROM, a broadly applicable metric that overcomes those limitations, and TSMD-Bench, a benchmark for quantitative evaluation of time series motif discovery. Experiments with PROM and TSMD-Bench show that PROM provides a more comprehensive evaluation than existing metrics, that TSMD-Bench is a more challenging benchmark than earlier ones, and that the combination can help understand the relative performance of TSMD methods. More generally, the proposed approach enables large-scale, systematic performance comparisons in this field.

The segmentation and classification of cardiac magnetic resonance imaging are critical for diagnosing heart conditions, yet current approaches face challenges in accuracy and generalizability. In this study, we aim to further advance the segmentation and classification of cardiac magnetic resonance images by introducing a novel deep learning-based approach. Using a multi-stage process with U-Net and ResNet models for segmentation, followed by Gaussian smoothing, the method improved segmentation accuracy, achieving a Dice coefficient of 0.974 for the left ventricle and 0.947 for the right ventricle. For classification, a cascade of deep learning classifiers was employed to distinguish heart conditions, including hypertrophic cardiomyopathy, myocardial infarction, and dilated cardiomyopathy, achieving an average accuracy of 97.2%. The proposed approach outperformed existing models, enhancing segmentation accuracy and classification precision. These advancements show promise for clinical applications, though further validation and interpretation across diverse imaging protocols is necessary.

Since classical machine learning has become a powerful tool for developing data-driven algorithms, quantum machine learning is expected to similarly impact the development of quantum algorithms. The literature reflects a mutually beneficial relationship between machine learning and quantum computing, where progress in one field frequently drives improvements in the other. Motivated by the fertile connection between machine learning and quantum computing enabled by parameterized quantum circuits, we use a resource-efficient and scalable Single-Qubit Quantum Neural Network (SQQNN) for both regression and classification tasks. The SQQNN leverages parameterized single-qubit unitary operators and quantum measurements to achieve efficient learning. To train the model, we use gradient descent for regression tasks. For classification, we introduce a novel training method inspired by the Taylor series, which can efficiently find a global minimum in a single step. This approach significantly accelerates training compared to iterative methods. Evaluated across various applications, the SQQNN exhibits virtually error-free and strong performance in regression and classification tasks, including the MNIST dataset. These results demonstrate the versatility, scalability, and suitability of the SQQNN for deployment on near-term quantum devices.

Recent latent-space monitoring techniques have shown promise as defenses against LLM attacks. These defenses act as scanners that seek to detect harmful activations before they lead to undesirable actions. This prompts the question: Can models execute harmful behavior via inconspicuous latent states? Here, we study such obfuscated activations. We show that state-of-the-art latent-space defenses -- including sparse autoencoders, representation probing, and latent OOD detection -- are all vulnerable to obfuscated activations. For example, against probes trained to classify harmfulness, our attacks can often reduce recall from 100% to 0% while retaining a 90% jailbreaking rate. However, obfuscation has limits: we find that on a complex task (writing SQL code), obfuscation reduces model performance. Together, our results demonstrate that neural activations are highly malleable: we can reshape activation patterns in a variety of ways, often while preserving a network's behavior. This poses a fundamental challenge to latent-space defenses.

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises volumetric measurements from brain MRI and genetic data from healthy individuals and patients with MCI/AD, obtained through the Alzheimer's Disease Neuroimaging Initiative. The existing class imbalance is addressed by an ensemble learning approach, while various attribution-based and counterfactual-based interpretability methods are leveraged towards producing diverse explanations related to the pathophysiology of MCI/AD. A unification method combining SHAP with counterfactual explanations assesses the interpretability techniques' robustness. The best performing model yielded 87.5% balanced accuracy and 90.8% F1-score. The attribution-based interpretability methods highlighted significant volumetric and genetic features related to MCI/AD risk. The unification method provided useful insights regarding those features' necessity and sufficiency, further showcasing their significance in MCI/AD diagnosis.

Motor imagery (MI) based brain-computer interfaces (BCIs) enable the direct control of external devices through the imagined movements of various body parts. Unlike previous systems that used fixed-length EEG trials for MI decoding, asynchronous BCIs aim to detect the user's MI without explicit triggers. They are challenging to implement, because the algorithm needs to first distinguish between resting-states and MI trials, and then classify the MI trials into the correct task, all without any triggers. This paper proposes a sliding window prescreening and classification (SWPC) approach for MI-based asynchronous BCIs, which consists of two modules: a prescreening module to screen MI trials out of the resting-state, and a classification module for MI classification. Both modules are trained with supervised learning followed by self-supervised learning, which refines the feature extractors. Within-subject and cross-subject asynchronous MI classifications on four different EEG datasets validated the effectiveness of SWPC, i.e., it always achieved the highest average classification accuracy, and outperformed the best state-of-the-art baseline on each dataset by about 2%.

Latent Video Diffusion Models can easily deceive casual observers and domain experts alike thanks to the produced image quality and temporal consistency. Beyond entertainment, this creates opportunities around safe data sharing of fully synthetic datasets, which are crucial in healthcare, as well as other domains relying on sensitive personal information. However, privacy concerns with this approach have not fully been addressed yet, and models trained on synthetic data for specific downstream tasks still perform worse than those trained on real data. This discrepancy may be partly due to the sampling space being a subspace of the training videos, effectively reducing the training data size for downstream models. Additionally, the reduced temporal consistency when generating long videos could be a contributing factor. In this paper, we first show that training privacy-preserving models in latent space is computationally more efficient and generalize better. Furthermore, to investigate downstream degradation factors, we propose to use a re-identification model, previously employed as a privacy preservation filter. We demonstrate that it is sufficient to train this model on the latent space of the video generator. Subsequently, we use these models to evaluate the subspace covered by synthetic video datasets and thus introduce a new way to measure the faithfulness of generative machine learning models. We focus on a specific application in healthcare echocardiography to illustrate the effectiveness of our novel methods. Our findings indicate that only up to 30.8% of the training videos are learned in latent video diffusion models, which could explain the lack of performance when training downstream tasks on synthetic data.

Mental manipulation severely undermines mental wellness by covertly and negatively distorting decision-making. While there is an increasing interest in mental health care within the natural language processing community, progress in tackling manipulation remains limited due to the complexity of detecting subtle, covert tactics in conversations. In this paper, we propose Intent-Aware Prompting (IAP), a novel approach for detecting mental manipulations using large language models (LLMs), providing a deeper understanding of manipulative tactics by capturing the underlying intents of participants. Experimental results on the MentalManip dataset demonstrate superior effectiveness of IAP against other advanced prompting strategies. Notably, our approach substantially reduces false negatives, helping detect more instances of mental manipulation with minimal misjudgment of positive cases. The code of this paper is available at https://github.com/Anton-Jiayuan-MA/Manip-IAP.

Intersectional fairness is a critical requirement for Machine Learning (ML) software, demanding fairness across subgroups defined by multiple protected attributes. This paper introduces FairHOME, a novel ensemble approach using higher order mutation of inputs to enhance intersectional fairness of ML software during the inference phase. Inspired by social science theories highlighting the benefits of diversity, FairHOME generates mutants representing diverse subgroups for each input instance, thus broadening the array of perspectives to foster a fairer decision-making process. Unlike conventional ensemble methods that combine predictions made by different models, FairHOME combines predictions for the original input and its mutants, all generated by the same ML model, to reach a final decision. Notably, FairHOME is even applicable to deployed ML software as it bypasses the need for training new models. We extensively evaluate FairHOME against seven state-of-the-art fairness improvement methods across 24 decision-making tasks using widely adopted metrics. FairHOME consistently outperforms existing methods across all metrics considered. On average, it enhances intersectional fairness by 47.5%, surpassing the currently best-performing method by 9.6 percentage points.