Advances in healthcare research have significantly enhanced our understanding of disease mechanisms, diagnostic precision, and therapeutic options. Yet, lung cancer remains one of the leading causes of cancer-related mortality worldwide due to challenges in early and accurate diagnosis. While current lung cancer detection models show promise, there is considerable potential for further improving the accuracy for timely intervention. To address this challenge, we introduce a hybrid deep convolution model leveraging transfer learning, named the Maximum Sensitivity Neural Network (MSNN). MSNN is designed to improve the precision of lung cancer detection by refining sensitivity and specificity. This model has surpassed existing deep learning approaches through experimental validation, achieving an accuracy of 98% and a sensitivity of 97%. By overlaying sensitivity maps onto lung Computed Tomography (CT) scans, it enables the visualization of regions most indicative of malignant or benign classifications. This innovative method demonstrates exceptional performance in distinguishing lung cancer with minimal false positives, thereby enhancing the accuracy of medical diagnoses.

Identifying tropical cyclones that generate destructive storm tides for risk assessment, such as from large downscaled storm catalogs for climate studies, is often intractable because it entails many expensive Monte Carlo hydrodynamic simulations. Here, we show that surrogate models are promising from accuracy, recall, and precision perspectives, and they "generalize" to novel climate scenarios. We then present an informative online learning approach to rapidly search for extreme storm tide-producing cyclones using only a few hydrodynamic simulations. Starting from a minimal subset of TCs with detailed storm tide hydrodynamic simulations, a surrogate model selects informative data to retrain online and iteratively improves its predictions of damaging TCs. Results on an extensive catalog of downscaled TCs indicate 100% precision in retrieving rare destructive storms using less than 20% of the simulations as training. The informative sampling approach is efficient, scalable to large storm catalogs, and generalizable to climate scenarios.

Security-Enhanced Linux (SELinux) is a robust security mechanism that enforces mandatory access controls (MAC), but its policy language's complexity creates challenges for policy analysis and management. This research investigates the automation of SELinux policy analysis using graph-based techniques combined with machine learning approaches to detect policy anomalies. The study addresses two key questions: Can SELinux policy analysis be automated through graph analysis, and how do different anomaly detection models compare in analyzing SELinux policies? We will be comparing different machine learning models by evaluating their effectiveness in detecting policy violations and anomalies. Our approach utilizes Neo4j for graph representation of policies, with Node2vec transforming these graph structures into meaningful vector embeddings that can be processed by our machine learning models. In our results, the MLP Neural Network consistently demonstrated superior performance across different dataset sizes, achieving 95% accuracy with balanced precision and recall metrics, while both Random Forest and SVM models showed competitive but slightly lower performance in detecting policy violations. This combination of graph-based modeling and machine learning provides a more sophisticated and automated approach to understanding and analyzing complex SELinux policies compared to traditional manual analysis methods.

Large language models and vision transformers have demonstrated impressive zero-shot capabilities, enabling significant transferability in downstream tasks. The fusion of these models has resulted in multi-modal architectures with enhanced instructional capabilities. Despite incorporating vast image and language pre-training, these multi-modal architectures often generate responses that deviate from the ground truth in the image data. These failure cases are known as hallucinations. Current methods for mitigating hallucinations generally focus on regularizing the language component, improving the fusion module, or ensembling multiple visual encoders to improve visual representation. In this paper, we address the hallucination issue by directly enhancing the capabilities of the visual component. Our approach, named EAGLE, is fully agnostic to the LLM or fusion module and works as a post-pretraining approach that improves the grounding and language alignment of the visual encoder. We show that a straightforward reformulation of the original contrastive pre-training task results in an improved visual encoder that can be incorporated into the instructional multi-modal architecture without additional instructional training. As a result, EAGLE achieves a significant reduction in hallucinations across multiple challenging benchmarks and tasks.

Existing methods for out-of-distribution (OOD) detection use various techniques to produce a score, separate from classification, that determines how ``OOD'' an input is. Our insight is that OOD detection can be simplified by using a neural network architecture which can effectively merge classification and OOD detection into a single step. Radial basis function networks (RBFNs) inherently link classification confidence and OOD detection; however, these networks have lost popularity due to the difficult of training them in a multi-layer fashion. In this work, we develop a multi-layer radial basis function network (MLRBFN) which can be easily trained. To ensure that these networks are also effective for OOD detection, we develop a novel depression mechanism. We apply MLRBFNs as standalone classifiers and as heads on top of pretrained feature extractors, and find that they are competitive with commonly used methods for OOD detection. Our MLRBFN architecture demonstrates a promising new direction for OOD detection methods.

In an era of escalating cyber threats, malware poses significant risks to individuals and organizations, potentially leading to data breaches, system failures, and substantial financial losses. This study addresses the urgent need for effective malware detection strategies by leveraging Machine Learning (ML) techniques on extensive datasets collected from Microsoft Windows Defender. Our research aims to develop an advanced ML model that accurately predicts malware vulnerabilities based on the specific conditions of individual machines. Moving beyond traditional signature-based detection methods, we incorporate historical data and innovative feature engineering to enhance detection capabilities. This study makes several contributions: first, it advances existing malware detection techniques by employing sophisticated ML algorithms; second, it utilizes a large-scale, real-world dataset to ensure the applicability of findings; third, it highlights the importance of feature analysis in identifying key indicators of malware infections; and fourth, it proposes models that can be adapted for enterprise environments, offering a proactive approach to safeguarding extensive networks against emerging threats. We aim to improve cybersecurity resilience, providing critical insights for practitioners in the field and addressing the evolving challenges posed by malware in a digital landscape. Finally, discussions on results, insights, and conclusions are presented.

While Vision-Language Models (VLMs) are increasingly used to generate reward signals for training embodied agents to follow instructions, our research reveals that agents guided by VLM rewards often underperform compared to those employing only intrinsic (exploration-driven) rewards, contradicting expectations set by recent work. We hypothesize that false positive rewards -- instances where unintended trajectories are incorrectly rewarded -- are more detrimental than false negatives. Our analysis confirms this hypothesis, revealing that the widely used cosine similarity metric is prone to false positive reward estimates. To address this, we introduce BiMI ({Bi}nary {M}utual {I}nformation), a novel reward function designed to mitigate noise. BiMI significantly enhances learning efficiency across diverse and challenging embodied navigation environments. Our findings offer a nuanced understanding of how different types of reward noise impact agent learning and highlight the importance of addressing multimodal reward signal noise when training embodied agents

Atypical gaze behavior is a diagnostic hallmark of Autism Spectrum Disorder (ASD), playing a substantial role in the social and communicative challenges that individuals with ASD face. This study explores the impacts of a month-long, in-home intervention designed to promote triadic interactions between a social robot, a child with ASD, and their caregiver. Our results indicate that the intervention successfully promoted appropriate gaze behavior, encouraging children with ASD to follow the robot's gaze, resulting in more frequent and prolonged instances of spontaneous eye contact and joint attention with their caregivers. Additionally, we observed specific timelines for behavioral variability and novelty effects among users. Furthermore, diagnostic measures for ASD emerged as strong predictors of gaze patterns for both caregivers and children. These results deepen our understanding of ASD gaze patterns and highlight the potential for clinical relevance of robot-assisted interventions.

Federated Learning (FL) has gained significant attention as it facilitates collaborative machine learning among multiple clients without centralizing their data on a server. FL ensures the privacy of participating clients by locally storing their data, which creates new challenges in fairness. Traditional debiasing methods assume centralized access to sensitive information, rendering them impractical for the FL setting. Additionally, FL is more susceptible to fairness issues than centralized machine learning due to the diverse client data sources that may be associated with group information. Therefore, training a fair model in FL without access to client local data is important and challenging. This paper presents AFed, a straightforward yet effective framework for promoting group fairness in FL. The core idea is to circumvent restricted data access by learning the global data distribution. This paper proposes two approaches: AFed-G, which uses a conditional generator trained on the server side, and AFed-GAN, which improves upon AFed-G by training a conditional GAN on the client side. We augment the client data with the generated samples to help remove bias. Our theoretical analysis justifies the proposed methods, and empirical results on multiple real-world datasets demonstrate a substantial improvement in AFed over several baselines.

Uncertainty quantification (UQ) is a critical aspect of artificial intelligence (AI) systems, particularly in high-risk domains such as healthcare, autonomous systems, and financial technology, where decision-making processes must account for uncertainty. This review explores the evolution of uncertainty quantification techniques in AI, distinguishing between aleatoric and epistemic uncertainties, and discusses the mathematical foundations and methods used to quantify these uncertainties. We provide an overview of advanced techniques, including probabilistic methods, ensemble learning, sampling-based approaches, and generative models, while also highlighting hybrid approaches that integrate domain-specific knowledge. Furthermore, we examine the diverse applications of UQ across various fields, emphasizing its impact on decision-making, predictive accuracy, and system robustness. The review also addresses key challenges such as scalability, efficiency, and integration with explainable AI, and outlines future directions for research in this rapidly developing area. Through this comprehensive survey, we aim to provide a deeper understanding of UQ's role in enhancing the reliability, safety, and trustworthiness of AI systems.