Abstract-- Transparency and explainability are important features that responsible autonomous vehicles should possess, particularly when interacting with humans, and causal reasoning offers a strong basis to provide these qualities. However, even if one assumes agents act to maximise some concept of reward, it is difficult to make accurate causal inferences of agent planning without capturing what is of importance to the agent. Thus our work aims to learn a weighting of reward metrics for agents such that explanations for agent interactions can be causally inferred. From here it is trivial to generate a textual explanation such as: "Red overtaking Autonomous systems are becoming increasingly prevalent in our day-to-day lives. Hence we ought to understand cause and effect in relation to their behaviour and the behaviour of others.

Sepsis is a life-threatening condition which requires rapid diagnosis and treatment. Traditional microbiological methods are time-consuming and expensive. In response to these challenges, deep learning algorithms were developed to identify 14 bacteria species and 3 yeast-like fungi from microscopic images of Gram-stained smears of positive blood samples from sepsis patients. A total of 16,637 Gram-stained microscopic images were used in the study. The analysis used the Cellpose 3 model for segmentation and Attention-based Deep Multiple Instance Learning for classification. Our model achieved an accuracy of 77.15% for bacteria and 71.39% for fungi, with ROC AUC of 0.97 and 0.88, respectively. The highest values, reaching up to 96.2%, were obtained for Cutibacterium acnes, Enterococcus faecium, Stenotrophomonas maltophilia and Nakaseomyces glabratus. Classification difficulties were observed in closely related species, such as Staphylococcus hominis and Staphylococcus haemolyticus, due to morphological similarity, and within Candida albicans due to high morphotic diversity. The study confirms the potential of our model for microbial classification, but it also indicates the need for further optimisation and expansion of the training data set. In the future, this technology could support microbial diagnosis, reducing diagnostic time and improving the effectiveness of sepsis treatment due to its simplicity and accessibility. Part of the results presented in this publication was covered by a patent application at the European Patent Office EP24461637.1 "A computer implemented method for identifying a microorganism in a blood and a data processing system therefor".

Background This study proposes a Vision-Language Model (VLM) leveraging the SIGLIP encoder and Gemma-3b transformer decoder to enhance automated chronic tuberculosis (TB) screening. By integrating chest X-ray images with clinical data, the model addresses the challenges of manual interpretation, improving diagnostic consistency and accessibility, particularly in resource-constrained settings. Methods The VLM architecture combines a Vision Transformer (ViT) for visual encoding and a transformer-based text encoder to process clinical context, such as patient histories and treatment records. Cross-modal attention mechanisms align radiographic features with textual information, while the Gemma-3b decoder generates comprehensive diagnostic reports. The model was pre-trained on 5 million paired medical images and texts and fine-tuned using 100,000 chronic TB-specific chest X-rays. Results The model demonstrated high precision (94 percent) and recall (94 percent) for detecting key chronic TB pathologies, including fibrosis, calcified granulomas, and bronchiectasis. Area Under the Curve (AUC) scores exceeded 0.93, and Intersection over Union (IoU) values were above 0.91, validating its effectiveness in detecting and localizing TB-related abnormalities. Conclusion The VLM offers a robust and scalable solution for automated chronic TB diagnosis, integrating radiographic and clinical data to deliver actionable and context-aware insights. Future work will address subtle pathologies and dataset biases to enhance the model's generalizability, ensuring equitable performance across diverse populations and healthcare settings.

Lameness and gait irregularities are significant concerns in equine health management, affecting performance, welfare, and economic value. Traditional observational methods rely on subjective expert assessments, which can lead to inconsistencies in detecting subtle or early-stage lameness. While AI-based approaches have emerged, many require multiple sensors, force plates, or video systems, making them costly and impractical for field deployment. In this applied research study, we present a stride-level classification system that utilizes a single inertial measurement unit (IMU) and a one-dimensional convolutional neural network (1D CNN) to objectively differentiate between sound and lame horses, with a primary focus on the trot gait. The proposed system was tested under real-world conditions, achieving a 90% session-level accuracy with no false positives, demonstrating its robustness for practical applications. By employing a single, non-intrusive, and readily available sensor, our approach significantly reduces the complexity and cost of hardware requirements while maintaining high classification performance. These results highlight the potential of our CNN-based method as a field-tested, scalable solution for automated lameness detection. By enabling early diagnosis, this system offers a valuable tool for preventing minor gait irregularities from developing into severe conditions, ultimately contributing to improved equine welfare and performance in veterinary and equestrian practice.

Semantic communication has emerged as a promising paradigm to tackle the challenges of massive growing data traffic and sustainable data communication. It shifts the focus from data fidelity to goal-oriented or task-oriented semantic transmission. While deep learning-based methods are commonly used for semantic encoding and decoding, they struggle with the sequential nature of time series data and high computation cost, particularly in resource-constrained IoT environments. Data compression plays a crucial role in reducing transmission and storage costs, yet traditional data compression methods fall short of the demands of goal-oriented communication systems. In this paper, we propose a novel method for direct analytics on time series data compressed by the SHRINK compression algorithm. Through experimentation using outlier detection as a case study, we show that our method outperforms baselines running on uncompressed data in multiple cases, with merely 1% difference in the worst case. Additionally, it achieves four times lower runtime on average and accesses approximately 10% of the data volume, which enables edge analytics with limited storage and computation power. These results demonstrate that our approach offers reliable, high-speed outlier detection analytics for diverse IoT applications while extracting semantics from time-series data, achieving high compression, and reducing data transmission.

Ligand strain energy, the energy difference between the bound and unbound conformations of a ligand, is an important component of structure-based small molecule drug design. A large majority of observed ligands in protein-small molecule co-crystal structures bind in low-strain conformations, making strain energy a useful filter for structure-based drug design. In this work we present a tool for calculating ligand strain with a high accuracy. StrainRelief uses a MACE Neural Network Potential (NNP), trained on a large database of Density Functional Theory (DFT) calculations to estimate ligand strain of neutral molecules with quantum accuracy. We show that this tool estimates strain energy differences relative to DFT to within 1.4 kcal/mol, more accurately than alternative NNPs. These results highlight the utility of NNPs in drug discovery, and provide a useful tool for drug discovery teams.

NLP models trained with differential privacy (DP) usually adopt the DP-SGD framework, and privacy guarantees are often reported in terms of the privacy budget $\epsilon$. However, $\epsilon$ does not have any intrinsic meaning, and it is generally not possible to compare across variants of the framework. Work in image processing has therefore explored how to empirically calibrate noise across frameworks using Membership Inference Attacks (MIAs). However, this kind of calibration has not been established for NLP. In this paper, we show that MIAs offer little help in calibrating privacy, whereas reconstruction attacks are more useful. As a use case, we define a novel kind of directional privacy based on the von Mises-Fisher (VMF) distribution, a metric DP mechanism that perturbs angular distance rather than adding (isotropic) Gaussian noise, and apply this to NLP architectures. We show that, even though formal guarantees are incomparable, empirical privacy calibration reveals that each mechanism has different areas of strength with respect to utility-privacy trade-offs.

Fire and smoke phenomena pose a significant threat to the natural environment, ecosystems, and global economy, as well as human lives and wildlife. In this particular circumstance, there is a demand for more sophisticated and advanced technologies to implement an effective strategy for early detection, real-time monitoring, and minimizing the overall impacts of fires on ecological balance and public safety. Recently, the rapid advancement of Artificial Intelligence (AI) and Computer Vision (CV) frameworks has substantially revolutionized the momentum for developing efficient fire management systems. However, these systems extensively rely on the availability of adequate and high-quality fire and smoke data to create proficient Machine Learning (ML) methods for various tasks, such as detection and monitoring. Although fire and smoke datasets play a critical role in training, evaluating, and testing advanced Deep Learning (DL) models, a comprehensive review of the existing datasets is still unexplored. For this purpose, we provide an in-depth review to systematically analyze and evaluate fire and smoke datasets collected over the past 20 years. We investigate the characteristics of each dataset, including type, size, format, collection methods, and geographical diversities. We also review and highlight the unique features of each dataset, such as imaging modalities (RGB, thermal, infrared) and their applicability for different fire management tasks (classification, segmentation, detection). Furthermore, we summarize the strengths and weaknesses of each dataset and discuss their potential for advancing research and technology in fire management. Ultimately, we conduct extensive experimental analyses across different datasets using several state-of-the-art algorithms, such as ResNet-50, DeepLab-V3, and YoloV8.

Biological signals, such as electroencephalograms (EEGs) and electrocardiograms (ECGs), play a pivotal role in numerous clinical practices, such as diagnosing brain and cardiac arrhythmic diseases. Existing methods for biosignal classification rely on Attention-based frameworks with dense Feed Forward layers, which lead to inefficient learning, high computational overhead, and suboptimal performance. In this work, we introduce BioMamba, a Spectro-Temporal Embedding strategy applied to the Bidirectional Mamba framework with Sparse Feed Forward layers to enable effective learning of biosignal sequences. By integrating these three key components, BioMamba effectively addresses the limitations of existing methods. Extensive experiments demonstrate that BioMamba significantly outperforms state-of-the-art methods with marked improvement in classification performance. The advantages of the proposed BioMamba include (1) Reliability: BioMamba consistently delivers robust results, confirmed across six evaluation metrics. (2) Efficiency: We assess both model and training efficiency, the BioMamba demonstrates computational effectiveness by reducing model size and resource consumption compared to existing approaches. (3) Generality: With the capacity to effectively classify a diverse set of tasks, BioMamba demonstrates adaptability and effectiveness across various domains and applications.

As large language models (LLMs) become increasingly capable, ensuring that their self-generated explanations are faithful to their internal decision-making process is critical for safety and oversight. In this work, we conduct a comprehensive counterfactual faithfulness analysis across 62 models from 8 families, encompassing both pretrained and instruction-tuned variants and significantly extending prior studies of counterfactual tests. We introduce phi-CCT, a simplified variant of the Correlational Counterfactual Test, which avoids the need for token probabilities while explaining most of the variance of the original test. Our findings reveal clear scaling trends: larger models are consistently more faithful on our metrics. However, when comparing instruction-tuned and human-imitated explanations, we find that observed differences in faithfulness can often be attributed to explanation verbosity, leading to shifts along the true-positive/false-positive Pareto frontier. While instruction-tuning and prompting can influence this trade-off, we find limited evidence that they fundamentally expand the frontier of explanatory faithfulness beyond what is achievable with pretrained models of comparable size. Our analysis highlights the nuanced relationship between instruction-tuning, verbosity, and the faithful representation of model decision processes.