The medical device industry has significantly advanced by integrating sophisticated electronics like microchips and field-programmable gate arrays (FPGAs) to enhance the safety and usability of life-saving devices. These complex electro-mechanical systems, however, introduce challenging failure modes that are not easily detectable with conventional methods. Effective fault detection and mitigation become vital as reliance on such electronics grows. This paper explores three generative machine learning-based approaches for fault detection in medical devices, leveraging sensor data from surgical staplers,a class 2 medical device. Historically considered low-risk, these devices have recently been linked to an increasing number of injuries and fatalities. The study evaluates the performance and data requirements of these machine-learning approaches, highlighting their potential to enhance device safety.

Prompt learning is one of the most effective paradigms for adapting pre-trained vision-language models (VLMs) to the biomedical image classification tasks in few shot scenarios. However, most of the current prompt learning methods only used the text prompts and ignored the particular structures (such as the complex anatomical structures and subtle pathological features) in the biomedical images. In this work, we propose Biomed-DPT, a knowledge-enhanced dual modality prompt tuning technique. In designing the text prompt, Biomed-DPT constructs a dual prompt including the template-driven clinical prompts and the large language model (LLM)-driven domain-adapted prompts, then extracts the clinical knowledge from the domain-adapted prompts through the knowledge distillation technique. In designing the vision prompt, Biomed-DPT introduces the zero vector as a soft prompt to leverage attention re-weighting so that the focus on non-diagnostic regions and the recognition of non-critical pathological features are avoided. Biomed-DPT achieves an average classification accuracy of 66.14\% across 11 biomedical image datasets covering 9 modalities and 10 organs, with performance reaching 78.06\% in base classes and 75.97\% in novel classes, surpassing the Context Optimization (CoOp) method by 6.20\%, 3.78\%, and 8.04\%, respectively. Our code are available at \underline{https://github.com/Kanyooo/Biomed-DPT}.

Conformal prediction is a powerful tool for constructing prediction intervals for black-box models, providing a finite sample coverage guarantee for exchangeable data. However, this exchangeability is compromised when some entries of the test feature are contaminated, such as in the case of cellwise outliers. To address this issue, this paper introduces a novel framework called detect-then-impute conformal prediction. This framework first employs an outlier detection procedure on the test feature and then utilizes an imputation method to fill in those cells identified as outliers. To quantify the uncertainty in the processed test feature, we adaptively apply the detection and imputation procedures to the calibration set, thereby constructing exchangeable features for the conformal prediction interval of the test label. We develop two practical algorithms, PDI-CP and JDI-CP, and provide a distribution-free coverage analysis under some commonly used detection and imputation procedures. Notably, JDI-CP achieves a finite sample $1-2α$ coverage guarantee. Numerical experiments on both synthetic and real datasets demonstrate that our proposed algorithms exhibit robust coverage properties and comparable efficiency to the oracle baseline.

Model monitoring is a critical component of the machine learning lifecycle, safeguarding against undetected drops in the model's performance after deployment. Traditionally, performance monitoring has required access to ground truth labels, which are not always readily available. This can result in unacceptable latency or render performance monitoring altogether impossible. Recently, methods designed to estimate the accuracy of classifier models without access to labels have shown promising results. However, there are various other metrics that might be more suitable for assessing model performance in many cases. Until now, none of these important metrics has received similar interest from the scientific community. In this work, we address this gap by presenting CBPE, a novel method that can estimate any binary classification metric defined using the confusion matrix. In particular, we choose four metrics from this large family: accuracy, precision, recall, and F$_1$, to demonstrate our method. CBPE treats the elements of the confusion matrix as random variables and leverages calibrated confidence scores of the model to estimate their distributions. The desired metric is then also treated as a random variable, whose full probability distribution can be derived from the estimated confusion matrix. CBPE is shown to produce estimates that come with strong theoretical guarantees and valid confidence intervals.

--With the high penetration of renewables, traditional model-based power system operation is challenged to deliver economic, stable, and robust decisions. Machine learning has emerged as a powerful modeling tool for capturing complex dynamics to address these challenges. However, its separate design often lacks systematic integration with existing methods. T o fill the gap, this paper proposes a holistic framework of Learning-Augmented Power System Operations (LAPSO, pronounced as Lap-So). Adopting a native optimization perspective, LAPSO is centered on the operation stage and aims to break the boundary between temporally siloed power system tasks, such as forecast, operation and control, while unifying the objectives of machine learning and model-based optimizations at both training and inference stages. Systematic analysis and simulations demonstrate the effectiveness of applying LAPSO in designing new integrated algorithms, such as stability-constrained optimization (SCO) and objective-based forecasting (OBF), while enabling end-to-end tracing of different sources of uncertainties. In addition, a dedicated Python package-lapso is introduced to automatically augment existing power system optimization models with learnable components. All code and data are available at https://github.com/xuwkk/lapso_exp. Index T erms --Power system operation, machine learning, objective-based forecasting, stability-constrained optimization. A. Background and Motivation Power system decision-making consists of sequentially connected tasks, including modeling/forecasting, operation, and control (See Figure 1(a).) With the decarbonization need, traditional model-based approaches face significant challenges. For example, the increasing uncertainty associated with renewable generation undermines the reliability of deterministic forecasting and power system operation (PSO) [2]. Meanwhile, the declining share of inertia from synchronous generators (SGs) can cause grid instability [3].

The safety of autonomous cars has come under scrutiny in recent years, especially after 16 documented incidents involving Teslas (with autopilot engaged) crashing into parked emergency vehicles (police cars, ambulances, and firetrucks). While previous studies have revealed that strong light sources often introduce flare artifacts in the captured image, which degrade the image quality, the impact of flare on object detection performance remains unclear. In this research, we unveil PaniCar, a digital phenomenon that causes an object detector's confidence score to fluctuate below detection thresholds when exposed to activated emergency vehicle lighting. This vulnerability poses a significant safety risk, and can cause autonomous vehicles to fail to detect objects near emergency vehicles. In addition, this vulnerability could be exploited by adversaries to compromise the security of advanced driving assistance systems (ADASs). We assess seven commercial ADASs (Tesla Model 3, "manufacturer C", HP, Pelsee, AZDOME, Imagebon, Rexing), four object detectors (YOLO, SSD, RetinaNet, Faster R-CNN), and 14 patterns of emergency vehicle lighting to understand the influence of various technical and environmental factors. We also evaluate four SOTA flare removal methods and show that their performance and latency are insufficient for real-time driving constraints. To mitigate this risk, we propose Caracetamol, a robust framework designed to enhance the resilience of object detectors against the effects of activated emergency vehicle lighting. Our evaluation shows that on YOLOv3 and Faster RCNN, Caracetamol improves the models' average confidence of car detection by 0.20, the lower confidence bound by 0.33, and reduces the fluctuation range by 0.33. In addition, Caracetamol is capable of processing frames at a rate of between 30-50 FPS, enabling real-time ADAS car detection.

Prompt tuning adapts Vision-Language Models like CLIP to open-world tasks with minimal training costs. In this direction, one typical paradigm evaluates model performance separately on known classes (i.e., base domain) and unseen classes (i.e., new domain). However, real-world scenarios require models to handle inputs without prior domain knowledge. This practical challenge has spurred the development of open-world prompt tuning, which demands a unified evaluation of two stages: 1) detecting whether an input belongs to the base or new domain (P1), and 2) classifying the sample into its correct class (P2). What's more, as domain distributions are generally unknown, a proper metric should be insensitive to varying base/new sample ratios (P3). However, we find that current metrics, including HM, overall accuracy, and AUROC, fail to satisfy these three properties simultaneously. To bridge this gap, we propose OpenworldAUC, a unified metric that jointly assesses detection and classification through pairwise instance comparisons. To optimize OpenworldAUC effectively, we introduce Gated Mixture-of-Prompts (GMoP), which employs domain-specific prompts and a gating mechanism to dynamically balance detection and classification. Theoretical guarantees ensure generalization of GMoP under practical conditions. Experiments on 15 benchmarks in open-world scenarios show GMoP achieves SOTA performance on OpenworldAUC and other metrics. We release the code at https://github.com/huacong/OpenworldAUC

Continuous authentication systems leveraging free - text keyboard dynamics offer a promising additional layer of security in a multifactor authentication setup that can be used in a transparent way with no impact on user experience. This study investigates t he efficacy of behavioral biometrics by employing an Agent - Based Model (ABM) to simulate diverse typing profiles across mechanical and membrane keyboards. Specifically, we generated synthetic keystroke data from five unique agents, capturing features relat ed to dwell time, flight time, and error rates within sliding 5 - second windows updated every second. Two machine learning approaches, One - Class Support V ector Machine (OC - SVM) and Random Forest (RF), were evaluated for user verification. Results revealed a stark contrast in performance: while One - Class SVM failed to differentiate individual users within each group, Random Forest achieved robust intra - keyboard user recognition (Accuracy > 0.7) but struggled to generalize across keyboards for the same user, h ighlighting the significant impact of keyboard hardware on typing behavior. These findings suggest that: (1) keyboard - specific user profiles may be necessary for reliable authentication, and (2) ensemble methods like RF outperform One - Class SVM in capturing fine - grained user - specific patterns. Keywords: keyboard dynamics, continuous authentication, agent - based modeling, One - Class SVM, Random Forest, behavioral biometrics.

Multimodal sentiment analysis, a pivotal task in affective computing, seeks to understand human emotions by integrating cues from language, audio, and visual signals. While many recent approaches leverage complex attention mechanisms and hierarchical architectures, we propose a lightweight, yet effective fusion-based deep learning model tailored for utterance-level emotion classification. Using the benchmark IEMOCAP dataset, which includes aligned text, audio-derived numeric features, and visual descriptors, we design a modality-specific encoder using fully connected layers followed by dropout regularization. The modality-specific representations are then fused using simple concatenation and passed through a dense fusion layer to capture cross-modal interactions. This streamlined architecture avoids computational overhead while preserving performance, achieving a classification accuracy of 92% across six emotion categories. Our approach demonstrates that with careful feature engineering and modular design, simpler fusion strategies can outperform or match more complex models, particularly in resource-constrained environments.

This article investigates the use of Machine Learning and Deep Learning models in multivariate time series analysis within financial markets. It compares small and big data approaches, focusing on their distinct challenges and the benefits of scaling. Traditional methods such as SVMs are contrasted with modern architectures like ConvTimeNet. The results show the importance of using and understanding Big Data in depth in the analysis and prediction of financial time series.