Accurate intraoperative diagnosis is essential for providing safe and effective care during brain tumor surgery.

Stochastic optimization of the Area Under the Precision-Recall Curve (AUPRC) is a crucial problem for machine learning. Although various algorithms have been extensively studied for AUPRC optimization, the generalization is only guaranteed in the multi-query case. In this work, we present the first trial in the single-query generalization of stochastic AUPRC optimization. For sharper generalization bounds, we focus on algorithm-dependent generalization. There are both algorithmic and theoretical obstacles to our destination.

This paper establishes the first polynomial convergence rates for Gaussian kernel ridge regression (KRR) with a fixed hyperparameter in both the uniform and the $L^{2}$-norm. The uniform convergence result closes a gap in the theoretical understanding of KRR with the Gaussian kernel, where no such rates were previously known. In addition, we prove a polynomial $L^{2}$-convergence rate in the case, where the Gaussian kernel's width parameter is fixed. This also contributes to the broader understanding of smooth kernels, for which previously only sub-polynomial $L^{2}$-rates were known in similar settings. Together, these results provide new theoretical justification for the use of Gaussian KRR with fixed hyperparameters in nonparametric regression.

As Multimodal Large Language Models (MLLMs) gain widespread applicability, it is becoming increasingly desirable to adapt them for diverse user needs. In this paper, we study the adaptation of MLLMs through controlled decoding. T o achieve this, we introduce the first method for reward-guided decoding of MLLMs and demonstrate its application in improving their visual grounding. Our method involves building reward models for visual grounding and using them to guide the MLLM's decoding process. Concretely, we build two separate reward models to independently control the degree of object precision and recall in the model's output. Our approach enables on-the-fly con-trollability of an MLLM's inference process in two ways: first, by giving control over the relative importance of each reward function during decoding, allowing a user to dynamically trade off object precision for recall in image captioning tasks; second, by giving control over the breadth of the search during decoding, allowing the user to control the trade-off between the amount of test-time compute and the degree of visual grounding. W e evaluate our method on standard object hallucination benchmarks, showing that it provides significant controllability over MLLM inference, while consistently outperforming existing hallucination mitigation methods.

Intelligent analysis of medical imaging plays a crucial role in assisting clinical diagnosis. However, achieving efficient and high-accuracy image classification in resource-constrained computational environments remains challenging. This study proposes a medical image classification method based on an improved ConvNeXt-Tiny architecture. Through structural optimization and loss function design, the proposed method enhances feature extraction capability and classification performance while reducing computational complexity. Specifically, the method introduces a dual global pooling (Global Average Pooling and Global Max Pooling) feature fusion strategy into the ConvNeXt-Tiny backbone to simultaneously preserve global statistical features and salient response information. A lightweight channel attention module, termed Squeeze-and-Excitation Vector (SEVector), is designed to improve the adaptive allocation of channel weights while minimizing parameter overhead. Additionally, a Feature Smoothing Loss is incorporated into the loss function to enhance intra-class feature consistency and suppress intra-class variance. Under CPU-only conditions (8 threads), the method achieves a maximum classification accuracy of 89.10% on the test set within 10 training epochs, exhibiting a stable convergence trend in loss values. Experimental results demonstrate that the proposed method effectively improves medical image classification performance in resource-limited settings, providing a feasible and efficient solution for the deployment and promotion of medical imaging analysis models.

Motor vehicle crashes remain a leading cause of injury and death worldwide, necessitating data-driven approaches to understand and mitigate crash severity. This study introduces a curated dataset of more than 3 million people involved in accidents in Ohio over six years (2017-2022), aggregated to more than 2.3 million vehicle-level records for predictive analysis. The primary contribution is a transparent and reproducible methodology that combines Automated Machine Learning (AutoML) and explainable artificial intelligence (AI) to identify and interpret key risk factors associated with severe crashes. Using the JADBio AutoML platform, predictive models were constructed to distinguish between severe and non-severe crash outcomes. The models underwent rigorous feature selection across stratified training subsets, and their outputs were interpreted using SHapley Additive exPlanations (SHAP) to quantify the contribution of individual features. A final Ridge Logistic Regression model achieved an AUC-ROC of 85.6% on the training set and 84.9% on a hold-out test set, with 17 features consistently identified as the most influential predictors. Key features spanned demographic, environmental, vehicle, human, and operational categories, including location type, posted speed, minimum occupant age, and pre-crash action. Notably, certain traditionally emphasized factors, such as alcohol or drug impairment, were less influential in the final model compared to environmental and contextual variables. Emphasizing methodological rigor and interpretability over mere predictive performance, this study offers a scalable framework to support Vision Zero with aligned interventions and advanced data-informed traffic safety policy.

Insider threat detection aims to identify malicious user behavior by analyzing logs that record user interactions. Due to the lack of fine-grained behavior-level annotations, detecting specific behavior-level anomalies within user behavior sequences is challenging. Unsupervised methods face high false positive rates and miss rates due to the inherent ambiguity between normal and anomalous behaviors. In this work, we instead introduce weak labels of behavior sequences, which have lower annotation costs, i.e., the training labels (anomalous or normal) are at sequence-level instead of behavior-level, to enhance the detection capability for behavior-level anomalies by learning discriminative features. To achieve this, we propose a novel framework called Robust Multi-sphere Learning (RMSL). RMSL uses multiple hyper-spheres to represent the normal patterns of behaviors. Initially, a one-class classifier is constructed as a good anomaly-supervision-free starting point. Building on this, using multiple instance learning and adaptive behavior-level self-training debiasing based on model prediction confidence, the framework further refines hyper-spheres and feature representations using weak sequence-level labels. This approach enhances the model's ability to distinguish between normal and anomalous behaviors. Extensive experiments demonstrate that RMSL significantly improves the performance of behavior-level insider threat detection.

Image segmentation is an important and widely performed task in computer vision. Accomplishing effective image segmentation in diverse settings often requires custom model architectures and loss functions. A set of models that specialize in segmenting thin tubular structures are topology preservation-based loss functions. These models often utilize a pixel skeletonization process claimed to generate more precise segmentation masks of thin tubes and better capture the structures that other models often miss. One such model, Skeleton Recall Loss (SRL) proposed by Kirchhoff et al.~\cite {kirchhoff2024srl}, was stated to produce state-of-the-art results on benchmark tubular datasets. In this work, we performed a theoretical analysis of the gradients for the SRL loss. Upon comparing the performance of the proposed method on some of the tubular datasets (used in the original work, along with some additional datasets), we found that the performance of SRL-based segmentation models did not exceed traditional baseline models. By providing both a theoretical explanation and empirical evidence, this work critically evaluates the limitations of topology-based loss functions, offering valuable insights for researchers aiming to develop more effective segmentation models for complex tubular structures.