Abstract-- As autonomous vehicles become an essential component of modern transportation, they are increasingly vulnerable to threats such as GPS spoofing attacks. This study presents an adaptive detection approach utilizing a dynamically tuned Density Based Spatial Clustering of Applications with Noise (DBSCAN) algorithm, designed to adjust the detection threshold (ε) in real-time. The threshold is updated based on the recursive mean and standard deviation of displacement errors between GPS and in-vehicle sensors data, but only at instances classified as non-anomalous. Furthermore, an initial threshold, determined from 120,000 clean data samples, ensures the capability to identify even subtle and gradual GPS spoofing attempts from the beginning. T o assess the performance of the proposed method, five different subsets from the real-world Honda Research Institute Driving Dataset (HDD) are selected to simulate both large and small magnitude GPS spoofing attacks. The modified algorithm effectively identifies turn-by-turn, stop, overshoot, and multiple small biased spoofing attacks, achieving detection accuracies of 98.62 1%, 99.96 0.1%, 99.88 0.1%, and 98.38 0.1%, respectively. This work provides a substantial advancement in enhancing the security and safety of A Vs against GPS spoofing threats.

Systematic reviews are crucial for synthesizing scientific evidence but remain labor-intensive, especially when extracting detailed methodological information. Large language models (LLMs) offer potential for automating methodological assessments, promising to transform evidence synthesis. Here, using causal mediation analysis as a representative methodological domain, we benchmarked state-of-the-art LLMs against expert human reviewers across 180 full-text scientific articles. Model performance closely correlated with human judgments (accuracy correlation 0.71; F1 correlation 0.97), achieving near-human accuracy on straightforward, explicitly stated methodological criteria. However, accuracy sharply declined on complex, inference-intensive assessments, lagging expert reviewers by up to 15%. Errors commonly resulted from superficial linguistic cues -- for instance, models frequently misinterpreted keywords like "longitudinal" or "sensitivity" as automatic evidence of rigorous methodological approache, leading to systematic misclassifications. Longer documents yielded lower model accuracy, whereas publication year showed no significant effect. Our findings highlight an important pattern for practitioners using LLMs for methods review and synthesis from full texts: current LLMs excel at identifying explicit methodological features but require human oversight for nuanced interpretations. Integrating automated information extraction with targeted expert review thus provides a promising approach to enhance efficiency and methodological rigor in evidence synthesis across diverse scientific fields.

We introduce a general stochastic differential equation framework for modelling multiobjective optimization dynamics in iterative Large Language Model (LLM) interactions. Our framework captures the inherent stochasticity of LLM responses through explicit diffusion terms and reveals systematic interference patterns between competing objectives via an interference matrix formulation. We validate our theoretical framework using iterative code generation as a proof-of-concept application, analyzing 400 sessions across security, efficiency, and functionality objectives. Our results demonstrate strategy-dependent convergence behaviors with rates ranging from 0.33 to 1.29, and predictive accuracy achieving R2 = 0.74 for balanced approaches. This work proposes the feasibility of dynamical systems analysis for multi-objective LLM interactions, with code generation serving as an initial validation domain.

The automated analysis of phonocardiograms is vital for the early diagnosis of cardiovascular disease, yet supervised deep learning is often constrained by the scarcity of expert-annotated data. In this paper, we propose the Self-Supervised Dual-Path Prototypical Network (SS-DPPN), a foundation model for cardiac audio representation and classification from unlabeled data. The framework introduces a dual-path contrastive learning based architecture that simultaneously processes 1D waveforms and 2D spectrograms using a novel hybrid loss. For the downstream task, a metric-learning approach using a Prototypical Network was used that enhances sensitivity and produces well-calibrated and trustworthy predictions. SS-DPPN achieves state-of-the-art performance on four cardiac audio benchmarks. The framework demonstrates exceptional data efficiency with a fully supervised model on three-fold reduction in labeled data. Finally, the learned representations generalize successfully across lung sound classification and heart rate estimation. Our experiments and findings validate SS-DPPN as a robust, reliable, and scalable foundation model for physiological signals.

The relative similarity testing aims to determine which of the distributions, P or Q, is closer to an anchor distribution U. Existing kernel-based approaches often test the relative similarity with a fixed kernel in a manually specified alternative hypothesis, e.g., Q is closer to U than P. Although kernel selection is known to be important to kernel-based testing methods, the manually specified hypothesis poses a significant challenge for kernel selection in relative similarity testing: Once the hypothesis is specified first, we can always find a kernel such that the hypothesis is rejected. This challenge makes relative similarity testing ill-defined when we want to select a good kernel after the hypothesis is specified. In this paper, we cope with this challenge via learning a proper hypothesis and a kernel simultaneously, instead of learning a kernel after manually specifying the hypothesis. We propose an anchor-based maximum discrepancy (AMD), which defines the relative similarity as the maximum discrepancy between the distances of (U, P) and (U, Q) in a space of deep kernels. Based on AMD, our testing incorporates two phases. In Phase I, we estimate the AMD over the deep kernel space and infer the potential hypothesis. In Phase II, we assess the statistical significance of the potential hypothesis, where we propose a unified testing framework to derive thresholds for tests over different possible hypotheses from Phase I. Lastly, we validate our method theoretically and demonstrate its effectiveness via extensive experiments on benchmark datasets. Codes are publicly available at: https://github.com/zhijianzhouml/AMD.

Uncertainty quantification for LLMs is a key research direction towards addressing hallucination and other issues that limit their reliable deployment. In this work, we show that reasoning trace length is a simple and useful confidence estimator in large reasoning models. Through comprehensive experiments across multiple models, datasets, and prompts, we show that trace length performs in comparable but complementary ways to other zero-shot confidence estimators such as verbalized confidence. Our work reveals that reasoning post-training fundamentally alters the relationship between trace length and accuracy, going beyond prior work that had shown that post-training causes traces to grow longer in general (e.g., "overthinking"). We investigate the mechanisms behind trace length's performance as a confidence signal, observing that the effect remains even after adjusting for confounders such as problem difficulty and GRPO-induced length bias. We identify high-entropy or "forking" tokens as playing a key role in the mechanism. Our findings demonstrate that reasoning post-training enhances uncertainty quantification beyond verbal expressions, and establish trace length as a practical confidence measure for large reasoning models.

Antidepressant nonadherence is pervasive, driving relapse, hospitalization, suicide risk, and billions in avoidable costs. Clinicians need tools that detect adherence lapses promptly, yet current methods are either invasive (serum assays, neuroimaging) or proxy-based and inaccurate (pill counts, pharmacy refills). We present the first noninvasive biomarker that detects antidepressant intake from a single night of sleep. A transformer-based model analyzes sleep data from a consumer wearable or contactless wireless sensor to infer antidepressant intake, enabling remote, effortless, daily adherence assessment at home. Across six datasets comprising 62,000 nights from >20,000 participants (1,800 antidepressant users), the biomarker achieved AUROC = 0.84, generalized across drug classes, scaled with dose, and remained robust to concomitant psychotropics. Longitudinal monitoring captured real-world initiation, tapering, and lapses. This approach offers objective, scalable adherence surveillance with potential to improve depression care and outcomes.

While ethical arguments for fairness in healthcare AI are well-established, the economic and strategic value of inclusive design remains underexplored. This perspective introduces the ``inclusive innovation dividend'' -- the counterintuitive principle that solutions engineered for diverse, constrained use cases generate superior economic returns in broader markets. Drawing from assistive technologies that evolved into billion-dollar mainstream industries, we demonstrate how inclusive healthcare AI development creates business value beyond compliance requirements. We identify four mechanisms through which inclusive innovation drives returns: (1) market expansion via geographic scalability and trust acceleration; (2) risk mitigation through reduced remediation costs and litigation exposure; (3) performance dividends from superior generalization and reduced technical debt, and (4) competitive advantages in talent acquisition and clinical adoption. We present the Healthcare AI Inclusive Innovation Framework (HAIIF), a practical scoring system that enables organizations to evaluate AI investments based on their potential to capture these benefits. HAIIF provides structured guidance for resource allocation, transforming fairness and inclusivity from regulatory checkboxes into sources of strategic differentiation. Our findings suggest that organizations investing incrementally in inclusive design can achieve expanded market reach and sustained competitive advantages, while those treating these considerations as overhead face compounding disadvantages as network effects and data advantages accrue to early movers.

The quickly growing popularity of AI companions poses risks to mental health, personal wellbeing, and social relationships. Past work has identified many individual factors that can drive human-companion interaction, but we know little about how these factors interact and evolve over time. In Study 1, we surveyed AI companion users (N = 303) to map the psychological pathway from users' mental models of the agent to parasocial experiences, social interaction, and the psychological impact of AI companions. Participants' responses foregrounded multiple interconnected variables (agency, parasocial interaction, and engagement) that shape AI companionship. In Study 2, we conducted a longitudinal study with a subset of participants (N = 110) using a new generic chatbot. Participants' perceptions of the generic chatbot significantly converged to perceptions of their own companions by Week 3. These results suggest a longitudinal model of AI companionship development and demonstrate an empirical method to study human-AI companionship.

Abstract-- Online sensing plays an important role in advancing modern manufacturing. The real-time sensor signals, which can be stored as high-resolution time series data, contain rich information about the operation status. One of its popular usages is online process monitoring, which can be achieved by effective anomaly detection from the sensor signals. However, most existing approaches either heavily rely on labeled data for training supervised models, or are designed to detect only extreme outliers, thus are ineffective at identifying subtle semantic off-track anomalies to capture where new regimes or unexpected routines start. T o address this challenge, we propose an matrix profile-based unsupervised anomaly detection algorithm that captures fabrication cycle similarity and performs semantic segmentation to precisely identify the onset of defect anomalies in additive manufacturing. The effectiveness of the proposed method is demonstrated by the experiments on real-world sensor data.