Current developments in molecular electronics, motors and chemical sensors could enable constructing large numbers of devices able to sense, compute and act in micron-scale environments. Such microscopic machines, of sizes comparable to bacteria, could simultaneously monitor entire populations of cells individually in vivo. This paper reviews plausible capabilities for microscopic robots and the physical constraints due to operation in fluids at low Reynolds number, diffusion-limited sensing and thermal noise from Brownian motion. Simple distributed controls are then presented in the context of prototypical biomedical tasks, which require control decisions on millisecond time scales. The resulting behaviors illustrate trade-offs among speed, accuracy and resource use. A specific example is monitoring for patterns of chemicals in a flowing fluid released at chemically distinctive sites. Information collected from a large number of such devices allows estimating properties of cell-sized chemical sources in a macroscopic volume. The microscopic devices moving with the fluid flow in small blood vessels can detect chemicals released by tissues in response to localized injury or infection. We find the devices can readily discriminate a single cell-sized chemical source from the background chemical concentration, providing high-resolution sensing in both time and space. By contrast, such a source would be difficult to distinguish from background when diluted throughout the blood volume as obtained with a blood sample.

Active learners alleviate the burden of labeling large amounts of data by detecting and asking the user to label only the most informative examples in the domain. We focus here on active learning for multi-view domains, in which there are several disjoint subsets of features (views), each of which is sufficient to learn the target concept. In this paper we make several contributions. First, we introduce Co-Testing, which is the first approach to multi-view active learning. Second, we extend the multi-view learning framework by also exploiting weak views, which are adequate only for learning a concept that is more general/specific than the target concept. Finally, we empirically show that Co-Testing outperforms existing active learners on a variety of real world domains such as wrapper induction, Web page classification, advertisement removal, and discourse tree parsing.

In this paper we propose a data intensive approach for inferring sentence-internal temporal relations. Temporal inference is relevant for practical NLP applications which either extract or synthesize temporal information (e.g., summarisation, question answering). Our method bypasses the need for manual coding by exploiting the presence of markers like ``after", which overtly signal a temporal relation. We first show that models trained on main and subordinate clauses connected with a temporal marker achieve good performance on a pseudo-disambiguation task simulating temporal inference (during testing the temporal marker is treated as unseen and the models must select the right marker from a set of possible candidates). Secondly, we assess whether the proposed approach holds promise for the semi-automatic creation of temporal annotations. Specifically, we use a model trained on noisy and approximate data (i.e., main and subordinate clauses) to predict intra-sentential relations present in TimeBank, a corpus annotated rich temporal information. Our experiments compare and contrast several probabilistic models differing in their feature space, linguistic assumptions and data requirements. We evaluate performance against gold standard corpora and also against human subjects.

There has been substantial progress in the past decade in the development of object classifiers for images, for example of faces, humans and vehicles. Here we address the problem of contaminations (e.g.

Machine learning is often used to automatically solve human tasks. In this paper, we look for tasks where machine learning algorithms are not as good as humans with the hope of gaining insight into their current limitations. We studied various Human Interactive Proofs (HIPs) on the market, because they are systems designed to tell computers and humans apart by posing challenges presumably too hard for computers. We found that most HIPs are pure recognition tasks which can easily be broken using machine learning.

There has been substantial progress in the past decade in the development of object classifiers for images, for example of faces, humans and vehicles. Here we address the problem of contaminations (e.g.

We provide a principle for semi-supervised learning based on optimizing the rate of communicating labels for unlabeled points with side information. The side information is expressed in terms of identities of sets of points or regions with the purpose of biasing the labels in each region to be the same. The resulting regularization objective is convex, has a unique solution, and the solution can be found with a pair of local propagation operations on graphs induced by the regions. We analyze the properties of the algorithm and demonstrate its performance on document classification tasks.

This paper proposes a method for computing fast approximations to support vector decision functions in the field of object detection. In the present approach we are building on an existing algorithm where the set of support vectors is replaced by a smaller, so-called reduced set of synthesized input space points. In contrast to the existing method that finds the reduced set via unconstrained optimization, we impose a structural constraint on the synthetic points such that the resulting approximations can be evaluated via separable filters. For applications that require scanning large images, this decreases the computational complexity by a significant amount. Experimental results show that in face detection, rank deficient approximations are 4 to 6 times faster than unconstrained reduced set systems.

The NIPS 2003 workshops included a feature selection competition organized by the authors. We provided participants with five datasets from different application domains and called for classification results using a minimal number of features. The competition took place over a period of 13 weeks and attracted 78 research groups. Participants were asked to make online submissions on the validation and test sets, with performance on the validation set being presented immediately to the participant and performance on the test set presented to the participants at the workshop. In total 1863 entries were made on the validation sets during the development period and 135 entries on all test sets for the final competition. The winners used a combination of Bayesian neural networks with ARD priors and Dirichlet diffusion trees. Other top entries used a variety of methods for feature selection, which combined filters and/or wrapper or embedded methods using Random Forests, kernel methods, or neural networks as a classification engine. The results of the benchmark (including the predictions made by the participants and the features they selected) and the scoring software are publicly available. The benchmark is available at www.nipsfsc.ecs.soton.ac.uk for post-challenge submissions to stimulate further research.

We describe a novel method for real-time, simultaneous multi-view face detection and facial pose estimation. The method employs a convolutional network to map face images to points on a manifold, parametrized by pose, and non-face images to points far from that manifold. This network is trained by optimizing a loss function of three variables: image, pose, and face/non-face label. We test the resulting system, in a single configuration, on three standard data sets - one for frontal pose, one for rotated faces, and one for profiles - and find that its performance on each set is comparable to previous multi-view face detectors that can only handle one form of pose variation. We also show experimentally that the system's accuracy on both face detection and pose estimation is improved by training for the two tasks together.