We consider the task of estimating a Gaussian graphical model in the high-dimensional setting. The graphical lasso, which involves maximizing the Gaussian log likelihood subject to an l1 penalty, is a well-studied approach for this task. We begin by introducing a surprising connection between the graphical lasso and hierarchical clustering: the graphical lasso in effect performs a two-step procedure, in which (1) single linkage hierarchical clustering is performed on the variables in order to identify connected components, and then (2) an l1-penalized log likelihood is maximized on the subset of variables within each connected component. In other words, the graphical lasso determines the connected components of the estimated network via single linkage clustering. Unfortunately, single linkage clustering is known to perform poorly in certain settings. Therefore, we propose the cluster graphical lasso, which involves clustering the features using an alternative to single linkage clustering, and then performing the graphical lasso on the subset of variables within each cluster. We establish model selection consistency for this technique, and demonstrate its improved performance relative to the graphical lasso in a simulation study, as well as in applications to an equities data set, a university webpage data set, and a gene expression data set.

Protein function prediction is the important problem in modern biology. In this paper, the un-normalized, symmetric normalized, and random walk graph Laplacian based semi-supervised learning methods will be applied to the integrated network combined from multiple networks to predict the functions of all yeast proteins in these multiple networks. These multiple networks are network created from Pfam domain structure, co-participation in a protein complex, protein-protein interaction network, genetic interaction network, and network created from cell cycle gene expression measurements. Multiple networks are combined with fixed weights instead of using convex optimization to determine the combination weights due to high time complexity of convex optimization method. This simple combination method will not affect the accuracy performance measures of the three semi-supervised learning methods. Experiment results show that the un-normalized and symmetric normalized graph Laplacian based methods perform slightly better than random walk graph Laplacian based method for integrated network. Moreover, the accuracy performance measures of these three semi-supervised learning methods for integrated network are much better than the best accuracy performance measures of these three methods for the individual network.

Crowdsourcing is an effective tool for human-powered computation on many tasks challenging for computers. In this paper, we provide finite-sample exponential bounds on the error rate (in probability and in expectation) of hyperplane binary labeling rules under the Dawid-Skene crowdsourcing model. The bounds can be applied to analyze many common prediction methods, including the majority voting and weighted majority voting. These bound results could be useful for controlling the error rate and designing better algorithms. We show that the oracle Maximum A Posterior (MAP) rule approximately optimizes our upper bound on the mean error rate for any hyperplane binary labeling rule, and propose a simple data-driven weighted majority voting (WMV) rule (called one-step WMV) that attempts to approximate the oracle MAP and has a provable theoretical guarantee on the error rate. Moreover, we use simulated and real data to demonstrate that the data-driven EM-MAP rule is a good approximation to the oracle MAP rule, and to demonstrate that the mean error rate of the data-driven EM-MAP rule is also bounded by the mean error rate bound of the oracle MAP rule with estimated parameters plugging into the bound.

The recommendation of additional shopping items that are potentially interesting for the customer has become a standard feature of modern online stores. In academia, research on recommender systems (RS) is mostly centered around approaches that rely on explicit item ratings and long-term user profiles. In practical environments, however, such rating information is often very sparse and for a large fraction of the users very little is known about their preferences. Furthermore, in particular when the shop offers products from a variety of categories, the decision of what should be recommended can strongly depend on the user's current short-term interests and the navigational context. In this paper, we report the results of an initial experimental analysis evaluating the predictive accuracy of different contextualized and non-contextualized recommendation strategies and discuss the question of appropriate experimental designs for such types of evaluations. To that purpose, we introduce a parameterizable protocol that supports session-specific accuracy measurements. Our analysis, which was based on log data obtained from a large online retailer for clothing and lifestyle products, shows that even a comparably simple contextual post-processing approach based on product features can leverage short-term user interests to increase the accuracy of the recommendations.

Anomaly detection for mixed-type data is an important problem that has not been well addressed in the machine learning field. There are two challenging issues for mixed-type datasets, namely modeling mutual correlations between mixed-type attributes and capturing large variations due to anomalies. This paper presents BuffDetect, a robust error buffering approach for anomaly detection in mixed-type datasets. A new variant of the generalized linear model is proposed to model the dependency between mixed-type attributes. The model incorporates an error buffering component based on Student-t distribution to absorb the variations caused by anomalies. However, because of the non- Gaussian design, the problem becomes analytically intractable. We propose a novel Bayesian inference approach, which integrates Laplace approximation and several computational optimizations, and is able to efficiently approximate the posterior of high dimensional latent variables by iteratively updating the latent variables in groups. Extensive experimental evaluations based on 13 benchmark datasets demonstrate the effectiveness and efficiency of BuffDetect.

Resampling techniques such as bagging are often used in supervised learning to produce more accurate classifiers. In this work, we show that multiple-instance learning admits a different form of resampling, which we call "shuffling." In shuffling, we resample instances in such a way that the resulting bags are likely to be correctly labeled. We show that resampling results in both a reduction of bag label noise and a propagation of additional informative constraints to a multiple-instance classifier. We empirically evaluate shuffling in the context of multiple-instance classification and multiple-instance active learning and show that the approach leads to significant improvements in accuracy.

Graphical models have gained a lot of attention recently as a tool for learning and representing dependencies among variables in multivariate data. Often, domain scientists are looking specifically for differences among the dependency networks of different conditions or populations (e.g. differences between regulatory networks of different species, or differences between dependency networks of diseased versus healthy populations). The standard method for finding these differences is to learn the dependency networks for each condition independently and compare them. We show that this approach is prone to high false discovery rates (low precision) that can render the analysis useless. We then show that by imposing a bias towards learning similar dependency networks for each condition the false discovery rates can be reduced to acceptable levels, at the cost of finding a reduced number of differences. Algorithms developed in the transfer learning literature can be used to vary the strength of the imposed similarity bias and provide a natural mechanism to smoothly adjust this differential precision-recall tradeoff to cater to the requirements of the analysis conducted. We present real case studies (oncological and neurological) where domain experts use the proposed technique to extract useful differential networks that shed light on the biological processes involved in cancer and brain function.

In massive open online courses (MOOCs), peer grading serves as a critical tool for scaling the grading of complex, open-ended assignments to courses with tens or hundreds of thousands of students. But despite promising initial trials, it does not always deliver accurate results compared to human experts. In this paper, we develop algorithms for estimating and correcting for grader biases and reliabilities, showing significant improvement in peer grading accuracy on real data with 63,199 peer grades from Coursera's HCI course offerings --- the largest peer grading networks analysed to date. We relate grader biases and reliabilities to other student factors such as student engagement, performance as well as commenting style. We also show that our model can lead to more intelligent assignment of graders to gradees.

Ensemble methods have been shown to be an effective tool for solving multi-label classification tasks. In the RAndom k-labELsets (RAKEL) algorithm, each member of the ensemble is associated with a small randomly-selected subset of k labels. Then, a single label classifier is trained according to each combination of elements in the subset. In this paper we adopt a similar approach, however, instead of randomly choosing subsets, we select the minimum required subsets of k labels that cover all labels and meet additional constraints such as coverage of inter-label correlations. Construction of the cover is achieved by formulating the subset selection as a minimum set covering problem (SCP) and solving it by using approximation algorithms. Every cover needs only to be prepared once by offline algorithms. Once prepared, a cover may be applied to the classification of any given multi-label dataset whose properties conform with those of the cover. The contribution of this paper is two-fold. First, we introduce SCP as a general framework for constructing label covers while allowing the user to incorporate cover construction constraints. We demonstrate the effectiveness of this framework by proposing two construction constraints whose enforcement produces covers that improve the prediction performance of random selection. Second, we provide theoretical bounds that quantify the probabilities of random selection to produce covers that meet the proposed construction criteria. The experimental results indicate that the proposed methods improve multi-label classification accuracy and stability compared with the RAKEL algorithm and to other state-of-the-art algorithms.

According to Daniel Kahneman, there are two systems that drive the human decision making process: The intuitive system that performs the fast thinking, and the deliberative system that does more logical and slower thinking. Inspired by this model, we propose a framework for implementing human activity recognition on mobile devices. In this area, the mobile app is usually always-on and the general challenge is how to balance accuracy and energy consumption. However, among existing approaches, those based on cellular IDs consume little power but are less accurate; those based on GPS/WiFi sampling are accurate often at the costs of battery drainage; moreover, previous methods in general do not improve over time. To address these challenges, our framework consists of two modes: In the deliberation mode, the system learns cell ID patterns that are trained by existing GPS/WiFi based methods; in the intuition mode, only the learned cell ID patterns are used for activity recognition, which is both accurate and energy-efficient; system parameters are learned to control the transition from deliberation to intuition, when sufficient confidence is gained, and the transition from intuition to deliberation, when more training is needed. For the scope of this paper, we first elaborate our framework in a subproblem in activity recognition, trip detection, which recognizes significant places and trips between them. For evaluation, we collected real-life traces of six participants over five months. Our experiments demonstrated consistent results across different participants in terms of accuracy and energy efficiency, and, more importantly, its fast improvement on energy efficiency over time due to regularities in human daily activities.