Artificial neural networks (ANNs) have gained a well-deserved popularity among machine learning tools upon their recent successful applications in image- and sound processing and classification problems. ANNs have also been applied for predicting the family or function of a protein, knowing its residue sequence. Here we present two new ANNs with multi-label classification ability, showing impressive accuracy when classifying protein sequences into 698 UniProt families (AUC=99.99%) and 983 Gene Ontology classes (AUC=99.45%).

WrestleMania 33 is easily WWE's biggest event of 2017, and it will be reflected in the length of Sunday's show. Between the kickoff show and the actual pay-per-view, the 13 matches on the card could span more than six hours. In order to catch every second of the action, fans should tune into WWE Network at 5 p.m. EDT when the kickoff show begins. The second hour of the kickoff show moves over to TV on USA at 6 p.m. EDT, and the PPV has a start time of 7 p.m. EDT. WWE PPVs usually end before 11 p.m. EDT (most start at 8 p.m. EDT), but that might not be the case Sunday night at Camping World Stadium in Orlando.

After months of rumors regarding WWE's biggest event of 2017, the WrestleMania 33 card is finally set. Thirteen matches are scheduled for Sunday's pay-per-view at Camping World Stadium in Orlando, and eight titles will be on the line. The WWE Universal Championship Match between Brock Lesnar and Goldberg is expected to go on last, putting an end to their feud that began with Goldberg's return in November. It seems to be clear which WWE superstar is winning the main event, but predictions for other matches aren't as easy to make. The SmackDown Tag Team Championships are the only belts that won't be defended at WrestleMania 33.

AI is helping cybersecurity but researchers are warning about over-promising. Cybersecurity pros shouldn't rely on artificial intelligence and machine learning just yet, according to a new report. The report from security firm Carbon Black, which surveyed 410 cybersecurity researchers and 74 percent said that AI-driven security solutions are flawed, citing "high false-positive rates", while 70 percent claimed attackers can bypass machine learning techniques. The respondents did not write off AI or machine learning as unhelpful but rather said that they just aren't there yet and cannot be solely relied on to make big decisions when it comes to security. AI and machine learning should be used "primarily to assist and augment human decision making," said the report.

A new machine-learning based security solution from IBM could help businesses detect phishing sites up to 250% faster than other methods. Announced via a blog post on Monday, the cognitive phishing detection feature is part of the IBM Security Trusteer platform. When it comes to hacking, phishing is one of the oldest tricks in the book. It has stayed around for so long, in part, because it still works. According to IBM Security research cited in the post, some 30% of phishing emails are opened by targeted recipients. Phishing works well because it capitalizes on the fact that humans are typically the weakest link in an organization's cybersecurity.

Automatic Music Transcription (AMT) is one of the oldest and most well-studied problems in the field of music information retrieval. Within this challenging research field, onset detection and instrument recognition take important places in transcription systems, as they respectively help to determine exact onset times of notes and to recognize the corresponding instrument sources. The aim of this study is to explore the usefulness of multiscale scattering operators for these two tasks on plucked string instrument and piano music. After resuming the theoretical background and illustrating the key features of this sound representation method, we evaluate its performances comparatively to other classical sound representations. Using both MIDI-driven datasets with real instrument samples and real musical pieces, scattering is proved to outperform other sound representations for these AMT subtasks, putting forward its richer sound representation and invariance properties.

Automatic Music Transcription (AMT) consists in automatically estimating the notes in an audio recording, through three attributes: onset time, duration and pitch. Probabilistic Latent Component Analysis (PLCA) has become very popular for this task. PLCA is a spectrogram factorization method, able to model a magnitude spectrogram as a linear combination of spectral vectors from a dictionary. Such methods use the Expectation-Maximization (EM) algorithm to estimate the parameters of the acoustic model. This algorithm presents well-known inherent defaults (local convergence, initialization dependency), making EM-based systems limited in their applications to AMT, particularly in regards to the mathematical form and number of priors. To overcome such limits, we propose in this paper to employ a different estimation framework based on Particle Filtering (PF), which consists in sampling the posterior distribution over larger parameter ranges. This framework proves to be more robust in parameter estimation, more flexible and unifying in the integration of prior knowledge in the system. Note-level transcription accuracies of 61.8 $\%$ and 59.5 $\%$ were achieved on evaluation sound datasets of two different instrument repertoires, including the classical piano (from MAPS dataset) and the marovany zither, and direct comparisons to previous PLCA-based approaches are provided. Steps for further development are also outlined.

In high-dimensional and/or non-parametric regression problems, regularization (or penalization) is used to control model complexity and induce desired structure. Each penalty has a weight parameter that indicates how strongly the structure corresponding to that penalty should be enforced. Typically the parameters are chosen to minimize the error on a separate validation set using a simple grid search or a gradient-free optimization method. It is more efficient to tune parameters if the gradient can be determined, but this is often difficult for problems with non-smooth penalty functions. Here we show that for many penalized regression problems, the validation loss is actually smooth almost-everywhere with respect to the penalty parameters. We can therefore apply a modified gradient descent algorithm to tune parameters. Through simulation studies on example regression problems, we find that increasing the number of penalty parameters and tuning them using our method can decrease the generalization error.

Datasets with hundreds of variables and many missing values are commonplace. In this setting, it is both statistically and computationally challenging to detect true predictive relationships between variables and also to suppress false positives. This paper proposes an approach that combines probabilistic programming, information theory, and non-parametric Bayes. It shows how to use Bayesian non-parametric modeling to (i) build an ensemble of joint probability models for all the variables; (ii) efficiently detect marginal independencies; and (iii) estimate the conditional mutual information between arbitrary subsets of variables, subject to a broad class of constraints. Users can access these capabilities using BayesDB, a probabilistic programming platform for probabilistic data analysis, by writing queries in a simple, SQL-like language. This paper demonstrates empirically that the method can (i) detect context-specific (in)dependencies on challenging synthetic problems and (ii) yield improved sensitivity and specificity over baselines from statistics and machine learning, on a real-world database of over 300 sparsely observed indicators of macroeconomic development and public health.

In the face of unmetered innovation across multiple industries, the banking industry has been rather quiet. For centuries, the banking industry has gone unscathed by the unrelenting tides of change. People still queue in banks to perform the simplest transactions. Appending the wrong signature on a check or form can lock you out of your bank account - or at the very least, turn your day into a nightmare. Thankfully, there are positive signs that the industry is slowly undergoing a transformation.