Link prediction is a fundamental problem with a wide range of applications in various domains, which predicts the links that are not yet observed or the links that may appear in the future. Most existing works in this field only focus on modeling a single network, while real-world networks are actually aligned with each other. Network alignments contain valuable additional information for understanding the networks, and provide a new direction for addressing data insufficiency and alleviating cold start problem. However, there are rare works leveraging network alignments for better link prediction. Besides, neural network is widely employed in various domains while its capability of capturing high-level patterns and correlations for link prediction problem has not been adequately researched yet. Hence, in this paper we target atlink prediction over aligned networks using neural networks. The major challenge is the heterogeneousness of the considered networks, as the networks may have different characteristics, link purposes, etc. To overcome this, we propose a novel multi-neural-network framework MNN, where we have one individual neural network for each heterogeneous target or feature while the vertex representations are shared. We further discuss training methods for the multi-neural-network framework. Extensive experiments demonstrate that MNN outperforms the state-of-the-art methods and achieves 3% to 5% relative improvement of AUC score across different settings, particularly over 8% for cold start scenarios.

We present a novel method for automated segmentation of overlapping cytoplasm in cervical smear images based on contour fragments. We formulate the segmentation problem as a graphical model, and employ the contour fragments generated from cytoplasm clump to construct the graph. Compared with traditional methods that are based on pixels, our contour fragment-based solution can take more geometric information into account and hence generate more accurate prediction of the overlapping boundaries. We further design a novel energy function for the graph, and by minimizing the energy function, fragments that come from the same cytoplasm are selected into the same set. To construct the energy function, our fragments-based data term and pairwise term are measured from the spatial relation and shape prior, which offer more geometric information for the occluded boundary inference. Afterwards, occluded boundaries are inferred using the minimal path model, in which shape of each individual cytoplasm is reconstructed on the selected fragments set. Constructed shape is used as a constraint to locate the searching area, and curvature regulation is enforced to promote the smoothness of inference result. The inference result, in turn, is used as the shape prior to construct a high-level shape regulation energy term of the built graph, and then graph energy is updated. In other words, fragments selection and occluded boundary inference are iterative processed; this interaction makes more potential shape information accessible. Using two cervical smear datasets, the performance of our method is extensively evaluated and compared with that of the state-of-the-art approaches; the results show the superiority of the proposed method.

With widespread use of machine learning methods in numerous domains involving humans, several studies have raised questions about the potential for unfairness towards certain individuals or groups. A number of recent works have proposed methods to measure and eliminate unfairness from machine learning models. However, most of this work has focused on only one dimension of fair decision making: distributive fairness, i.e., the fairness of the decision outcomes. In this work, we leverage the rich literature on organizational justice and focus on another dimension of fair decision making: procedural fairness, i.e., the fairness of the decision making process. We propose measures for procedural fairness that consider the input features used in the decision process, and evaluate the moral judgments of humans regarding the use of these features. We operationalize these measures on two real world datasets using human surveys on the Amazon Mechanical Turk (AMT) platform, demonstrating that our measures capture important properties of procedurally fair decision making. We provide fast submodular mechanisms to optimize the tradeoff between procedural fairness and prediction accuracy. On our datasets, we observe empirically that procedural fairness may be achieved with little cost to outcome fairness, but that some loss of accuracy is unavoidable.

Many information retrieval tasks rely on high dimensional searches, including K-nearest neighbors (KNN), approximate nearest neighbors (ANN), and exact r-neighbor lookup in Hamming space. At scale, these searches are enabled by indexes on binary hashes, such as locality-sensitive hashing (LSH) and multi-indexing [1]. Recent research has flourished on these topics due to enormous growth in data volume and industry applications [2]. We present a powerful new approach to a fundamental challenge in these tasks: learning a good binary hash function. We demonstrate the effectiveness of our method by applying it to the task of automated scene matching (ASM) with a multi-index system. We call our model convolutional hashing for automated scene matching (CHASM). To the best of our knowledge, it is the first neural network to outperform state-of-the-art hash functions like Haar wavelets and color layout descriptors at ASM across the board.

Machine learning has become an important component for many systems and applications including computer vision, spam filtering, malware and network intrusion detection, among others. Despite the capabilities of machine learning algorithms to extract valuable information from data and produce accurate predictions, it has been shown that these algorithms are vulnerable to attacks. Data poisoning is one of the most relevant security threats against machine learning systems, where attackers can subvert the learning process by injecting malicious samples in the training data. Recent work in adversarial machine learning has shown that the so-called optimal attack strategies can successfully poison linear classifiers, degrading the performance of the system dramatically after compromising a small fraction of the training dataset. In this paper we propose a defence mechanism to mitigate the effect of these optimal poisoning attacks based on outlier detection. We show empirically that the adversarial examples generated by these attack strategies are quite different from genuine points, as no detectability constrains are considered to craft the attack. Hence, they can be detected with an appropriate pre-filtering of the training dataset.

There is a lot of new technology, a huge demand for our skills, and a bright future that promises only more work for us. Yet, this excitement is a two-edged blade. We often hear from peers about how hard it is to hire good security folks. My email box gets at least one mention a week from a peer looking for folks to bolster their team. But beyond anecdotes, we have data, as well.

Melanoma is the deadliest form of skin cancer. Computer systems can assist in melanoma detection, but are not widespread in clinical practice. In 2016, an open challenge in classification of dermoscopic images of skin lesions was announced. A training set of 900 images with corresponding class labels and semi-automatic/manual segmentation masks was released for the challenge. An independent test set of 379 images was used to rank the participants. This article demonstrates the impact of ranking criteria, segmentation method and classifier, and highlights the clinical perspective. We compare five different measures for diagnostic accuracy by analysing the resulting ranking of the computer systems in the challenge. Choice of performance measure had great impact on the ranking. Systems that were ranked among the top three for one measure, dropped to the bottom half when changing performance measure. Nevus Doctor, a computer system previously developed by the authors, was used to investigate the impact of segmentation and classifier. The unexpected small impact of automatic versus semi-automatic/manual segmentation suggests that improvements of the automatic segmentation method w.r.t. resemblance to semi-automatic/manual segmentation will not improve diagnostic accuracy substantially. A small set of similar classification algorithms are used to investigate the impact of classifier on the diagnostic accuracy. The variability in diagnostic accuracy for different classifier algorithms was larger than the variability for segmentation methods, and suggests a focus for future investigations. From a clinical perspective, the misclassification of a melanoma as benign has far greater cost than the misclassification of a benign lesion. For computer systems to have clinical impact, their performance should be ranked by a high-sensitivity measure.

For a graph representation of a dataset, a straightforward normality measure for a sample can be its graph degree. Considering a weighted graph, degree of a sample is the sum of the corresponding row's values in a similarity matrix. The measure is intuitive given the abnormal samples are usually rare and they are dissimilar to the rest of the data. In order to have an in-depth theoretical understanding, in this manuscript, we investigate the graph degree in spectral graph clustering based and kernel based point of views and draw connections to a recent kernel method for the two sample problem. We show that our analyses guide us to choose fully-connected graphs whose edge weights are calculated via universal kernels. We show that a simple graph degree based unsupervised anomaly detection method with the above properties, achieves higher accuracy compared to other unsupervised anomaly detection methods on average over 10 widely used datasets. We also provide an extensive analysis on the effect of the kernel parameter on the method's accuracy.

A key step to driver safety is to observe the driver's activities with the face being a key step in this process to extracting information such as head pose, blink rate, yawns, talking to passenger which can then help derive higher level information such as distraction, drowsiness, intent, and where they are looking. In the context of driving safety, it is important for the system perform robust estimation under harsh lighting and occlusion but also be able to detect when the occlusion occurs so that information predicted from occluded parts of the face can be taken into account properly. This paper introduces the Occluded Stacked Hourglass, based on the work of original Stacked Hourglass network for body pose joint estimation, which is retrained to process a detected face window and output 68 occlusion heat maps, each corresponding to a facial landmark. Landmark location, occlusion levels and a refined face detection score, to reject false positives, are extracted from these heat maps. Using the facial landmark locations, features such as head pose and eye/mouth openness can be extracted to derive driver attention and activity. The system is evaluated for face detection, head pose, and occlusion estimation on various datasets in the wild, both quantitatively and qualitatively, and shows state-of-the-art results.

Computed tomography (CT) examinations are commonly used to predict lung nodule malignancy in patients, which are shown to improve noninvasive early diagnosis of lung cancer. It remains challenging for computational approaches to achieve performance comparable to experienced radiologists. Here we present NoduleX, a systematic approach to predict lung nodule malignancy from CT data, based on deep learning convolutional neural networks (CNN). For training and validation, we analyze >1000 lung nodules in images from the LIDC/IDRI cohort. All nodules were identified and classified by four experienced thoracic radiologists who participated in the LIDC project. NoduleX achieves high accuracy for nodule malignancy classification, with an AUC of ~0.99. This is commensurate with the analysis of the dataset by experienced radiologists. Our approach, NoduleX, provides an effective framework for highly accurate nodule malignancy prediction with the model trained on a large patient population. Our results are replicable with software available at http://bioinformatics.astate.edu/NoduleX.