Deep Neural Networks are powerful models that attained remarkable results on a variety of tasks. These models are shown to be extremely efficient when training and test data are drawn from the same distribution. However, it is not clear how a network will act when it is fed with an out-of-distribution example. In this work, we consider the problem of out-of-distribution detection in neural networks. We propose to use multiple semantic dense representations instead of sparse representation as the target label. Specifically, we propose to use several word representations obtained from different corpora or architectures as target labels. We evaluated the proposed model on computer vision, and speech commands detection tasks and compared it to previous methods. Results suggest that our method compares favorably with previous work. Besides, we present the efficiency of our approach for detecting wrongly classified and adversarial examples.

A large number of papers have introduced novel machine learning and feature extraction methods for automatic classification of AD. However, they are difficult to reproduce because key components of the validation are often not readily available. These components include selected participants and input data, image preprocessing and cross-validation procedures. The performance of the different approaches is also difficult to compare objectively. In particular, it is often difficult to assess which part of the method provides a real improvement, if any. We propose a framework for reproducible and objective classification experiments in AD using three publicly available datasets (ADNI, AIBL and OASIS). The framework comprises: i) automatic conversion of the three datasets into BIDS format, ii) a modular set of preprocessing pipelines, feature extraction and classification methods, together with an evaluation framework, that provide a baseline for benchmarking the different components. We demonstrate the use of the framework for a large-scale evaluation on 1960 participants using T1 MRI and FDG PET data. In this evaluation, we assess the influence of different modalities, preprocessing, feature types, classifiers, training set sizes and datasets. Performances were in line with the state-of-the-art. FDG PET outperformed T1 MRI for all classification tasks. No difference in performance was found for the use of different atlases, image smoothing, partial volume correction of FDG PET images, or feature type. Linear SVM and L2-logistic regression resulted in similar performance and both outperformed random forests. The classification performance increased along with the number of subjects used for training. Classifiers trained on ADNI generalized well to AIBL and OASIS. All the code of the framework and the experiments is publicly available at: https://gitlab.icm-institute.org/aramislab/AD-ML.

Survival analysis in the presence of multiple possible adverse events, i.e., competing risks, is a pervasive problem in many industries (healthcare, finance, etc.). Since only one event is typically observed, the incidence of an event of interest is often obscured by other related competing events. This nonidentifiability, or inability to estimate true cause-specific survival curves from empirical data, further complicates competing risk survival analysis. We introduce Siamese Survival Prognosis Network (SSPN), a novel deep learning architecture for estimating personalized risk scores in the presence of competing risks. SSPN circumvents the nonidentifiability problem by avoiding the estimation of cause-specific survival curves and instead determines pairwise concordant time-dependent risks, where longer event times are assigned lower risks. Furthermore, SSPN is able to directly optimize an approximation to the C-discrimination index, rather than relying on well-known metrics which are unable to capture the unique requirements of survival analysis with competing risks.

Machine learning has become one of the main components for task automation in many application domains. Despite the advancements and impressive achievements of machine learning, it has been shown that learning algorithms can be compromised by attackers both at training and test time. Machine learning systems are especially vulnerable to adversarial examples where small perturbations added to the original data points can produce incorrect or unexpected outputs in the learning algorithms at test time. Mitigation of these attacks is hard as adversarial examples are difficult to detect. Existing related work states that the security of machine learning systems against adversarial examples can be weakened when feature selection is applied to reduce the systems' complexity. In this paper, we empirically disprove this idea, showing that the relative distortion that the attacker has to introduce to succeed in the attack is greater when the target is using a reduced set of features. We also show that the minimal adversarial examples differ statistically more strongly from genuine examples with a lower number of features. However, reducing the feature count can negatively impact the system's performance. We illustrate the trade-off between security and accuracy with specific examples. We propose a design methodology to evaluate the security of machine learning classifiers with embedded feature selection against adversarial examples crafted using different attack strategies.

From self-driving vehicles and back-flipping robots to virtual assistants who book our next appointment at the hair salon or at that restaurant for dinner - machine learning systems are becoming increasingly ubiquitous. The main reason for this is that these methods boast remarkable predictive capabilities. However, most of these models remain black boxes, meaning that it is very challenging for humans to follow and understand their intricate inner workings. Consequently, interpretability has suffered under this ever-increasing complexity of machine learning models. Especially with regards to new regulations, such as the General Data Protection Regulation (GDPR), the necessity for plausibility and verifiability of predictions made by these black boxes is indispensable. Driven by the needs of industry and practice, the research community has recognised this interpretability problem and focussed on developing a growing number of so-called explanation methods over the past few years. These methods explain individual predictions made by black box machine learning models and help to recover some of the lost interpretability. With the proliferation of these explanation methods, it is, however, often unclear, which explanation method offers a higher explanation quality, or is generally better-suited for the situation at hand. In this thesis, we thus propose an axiomatic framework, which allows comparing the quality of different explanation methods amongst each other. Through experimental validation, we find that the developed framework is useful to assess the explanation quality of different explanation methods and reach conclusions that are consistent with independent research.

For hiring machine learning engineers or data scientist, the typical process has multiple rounds. A typical first round of interview consists of three parts. A typical interviewer will start by asking about the relevant work from your profile. On your past experience of machine learning project, the interviewer might ask how would you improve it. Afterwards (third part), the interviewer would proceed to check your basic knowledge of machine learning on the following lines.

Active learning stands for methods which increase classification quality by means of user feedback. An important subcategory is active learning for one-class classifiers, i.e., for imbalanced class distributions. While various methods in this category exist, selecting one for a given application scenario is difficult. This is because existing methods rely on different assumptions, have different objectives, and often are tailored to a specific use case. All this calls for a comprehensive comparison, the topic of this article. This article starts with a categorization of the various methods. We then propose ways to evaluate active learning results. Next, we run extensive experiments to compare existing methods, for a broad variety of scenarios. One result is that the practicality and the performance of an active learning method strongly depend on its category and on the assumptions behind it. Another observation is that there only is a small subset of our experiments where existing approaches outperform random baselines. Finally, we show that a well-laid-out categorization and a rigorous specification of assumptions can facilitate the selection of a good method for one-class classification.

Identifying current and future informal regions within cities remains a crucial issue for policymakers and governments in developing countries. The delineation process of identifying such regions in cities requires a lot of resources. While there are various studies that identify informal settlements based on satellite image classification, relying on both supervised or unsupervised machine learning approaches, these models either require multiple input data to function or need further development with regards to precision. In this paper, we introduce a novel method for identifying and predicting informal settlements using only street intersections data, regardless of the variation of urban form, number of floors, materials used for construction or street width. With such minimal input data, we attempt to provide planners and policy-makers with a pragmatic tool that can aid in identifying informal zones in cities. The algorithm of the model is based on spatial statistics and a machine learning approach, using Multinomial Logistic Regression (MNL) and Artificial Neural Networks (ANN). The proposed model relies on defining informal settlements based on two ubiquitous characteristics that these regions tend to be filled in with smaller subdivided lots of housing relative to the formal areas within the local context, and the paucity of services and infrastructure within the boundary of these settlements that require relatively bigger lots. We applied the model in five major cities in Egypt and India that have spatial structures in which informality is present. These cities are Greater Cairo, Alexandria, Hurghada and Minya in Egypt, and Mumbai in India. The predictSLUMS model shows high validity and accuracy for identifying and predicting informality within the same city the model was trained on or in different ones of a similar context.

Data visualization should be accessible for all analysts with data, not just the few with technical expertise. Visualization recommender systems aim to lower the barrier to exploring basic visualizations by automatically generating results for analysts to search and select, rather than manually specify. Here, we demonstrate a novel machine learning-based approach to visualization recommendation that learns visualization design choices from a large corpus of datasets and associated visualizations. First, we identify five key design choices made by analysts while creating visualizations, such as selecting a visualization type and choosing to encode a column along the X- or Y-axis. We train models to predict these design choices using one million dataset-visualization pairs collected from a popular online visualization platform. Neural networks predict these design choices with high accuracy compared to baseline models. We report and interpret feature importances from one of these baseline models. To evaluate the generalizability and uncertainty of our approach, we benchmark with a crowdsourced test set, and show that the performance of our model is comparable to human performance when predicting consensus visualization type, and exceeds that of other ML-based systems.

Acute Kidney Injury (AKI), a sudden decline in kidney function, is associated with increased mortality, morbidity, length of stay, and hospital cost. Since AKI is sometimes preventable, there is great interest in prediction. Most existing studies consider all patients and therefore restrict to features available in the first hours of hospitalization. Here, the focus is instead on rehospitalized patients, a cohort in which rich longitudinal features from prior hospitalizations can be analyzed. Our objective is to provide a risk score directly at hospital re-entry. Gradient boosting, penalized logistic regression (with and without stability selection), and a recurrent neural network are trained on two years of adult inpatient EHR data (3,387 attributes for 34,505 patients who generated 90,013 training samples with 5,618 cases and 84,395 controls). Predictions are internally evaluated with 50 iterations of 5-fold grouped cross-validation with special emphasis on calibration, an analysis of which is performed at the patient as well as hospitalization level. Error is assessed with respect to diagnosis, race, age, gender, AKI identification method, and hospital utilization. In an additional experiment, the regularization penalty is severely increased to induce parsimony and interpretability. Predictors identified for rehospitalized patients are also reported with a special analysis of medications that might be modifiable risk factors. Insights from this study might be used to construct a predictive tool for AKI in rehospitalized patients. An accurate estimate of AKI risk at hospital entry might serve as a prior for an admitting provider or another predictive algorithm.