BACKGROUND AND PURPOSE: Alberta Stroke Program Early CT Score (ASPECTS) was devised as a systematic method to assess the extent of early ischemic change on noncontrast CT (NCCT) in patients with acute ischemic stroke (AIS). Our aim was to automate ASPECTS to objectively score NCCT of AIS patients. MATERIALS AND METHODS: We collected NCCT images with a 5-mm thickness of 257 patients with acute ischemic stroke ( 8 hours from onset to scans) followed by a diffusion-weighted imaging acquisition within 1 hour. Expert ASPECTS readings on DWI were used as ground truth. Texture features were extracted from each ASPECTS region of the 157 training patient images to train a random forest classifier. The unseen 100 testing patient images were used to evaluate the performance of the trained classifier.

Wind power, as an alternative to burning fossil fuels, is plentiful and renewable. Data-driven approaches are increasingly popular for inspecting the wind turbine failures. In this paper, we propose a novel classification-based anomaly detection system for icing detection of the wind turbine blades. We effectively combine the deep neural networks and wavelet transformation to identify such failures sequentially across the time. In the training phase, we present a wavelet based fully convolutional neural network (FCNN), namely WaveletFCNN, for the time series classification. We improve the original (FCNN) by augmenting features with the wavelet coefficients. WaveletFCNN outperforms the state-of-the-art FCNN for the univariate time series classification on the UCR time series archive benchmarks. In the detecting phase, we combine the sliding window and majority vote algorithms to provide the timely monitoring of the anomalies. The system has been successfully implemented on a real-world dataset from Goldwind Inc, where the classifier is trained on a multivariate time series dataset and the monitoring algorithm is implemented to capture the abnormal condition on signals from a wind farm.

We investigate conditions under which test statistics exist that can reliably detect examples, which have been adversarially manipulated in a white-box attack. These statistics can be easily computed and calibrated by randomly corrupting inputs. They exploit certain anomalies that adversarial attacks introduce, in particular if they follow the paradigm of choosing perturbations optimally under p-norm constraints. Access to the log-odds is the only requirement to defend models. We justify our approach empirically, but also provide conditions under which detectability via the suggested test statistics is guaranteed to be effective. In our experiments, we show that it is even possible to correct test time predictions for adversarial attacks with high accuracy.

Manifold regularization, such as laplacian regularized least squares (LapRLS) and laplacian support vector machine (LapSVM), has been widely used in semi-supervised learning, and its performance greatly depends on the choice of some hyper-parameters. Cross-validation (CV) is the most popular approach for selecting the optimal hyper-parameters, but it has high complexity due to multiple times of learner training. In this paper, we provide a method to approximate the CV for manifold regularization based on a notion of robust statistics, called Bouligand influence function (BIF). We first provide a strategy for approximating the CV via the Taylor expansion of BIF. Then, we show how to calculate the BIF for general loss function,and further give the approximate CV criteria for model selection in manifold regularization. The proposed approximate CV for manifold regularization requires training only once, hence can significantly improve the efficiency of traditional CV. Experimental results show that our approximate CV has no statistical discrepancy with the original one, but much smaller time cost.

Artificial Intelligence (AI) is necessary to address the large and growing deficit in retina and healthcare access globally. And mobile AI diagnostic platforms running in the Cloud may effectively and efficiently distribute such AI capability. Here we sought to evaluate the feasibility of Cloud-based mobile artificial intelligence for detection of retinal disease. And to evaluate the accuracy of a particular such system for detection of subretinal fluid (SRF) and macula edema (ME) on OCT scans. A multicenter retrospective image analysis was conducted in which board-certified ophthalmologists with fellowship training in retina evaluated OCT images of the macula. They noted the presence or absence of ME or SRF, then compared their assessment to that obtained from Fluid Intelligence, a mobile AI app that detects SRF and ME on OCT scans. Investigators consecutively selected retinal OCTs, while making effort to balance the number of scans with retinal fluid and scans without. Exclusion criteria included poor scan quality, ambiguous features, macula holes, retinoschisis, and dense epiretinal membranes. Accuracy in the form of sensitivity and specificity of the AI mobile App was determined by comparing its assessments to those of the retina specialists. At the time of this submission, five centers have completed their initial studies. This consists of a total of 283 OCT scans of which 155 had either ME or SRF ("wet") and 128 did not ("dry"). The sensitivity ranged from 82.5% to 97% with a weighted average of 89.3%. The specificity ranged from 52% to 100% with a weighted average of 81.23%. CONCLUSION: Cloud-based Mobile AI technology is feasible for the detection retinal disease. In particular, Fluid Intelligence (alpha version), is sufficiently accurate as a screening tool for SRF and ME, especially in underserved areas. Further studies and technology development is needed.

Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs which play a significant role in several biological processes. RNA-seq based transcriptome sequencing has been extensively used for identification of lncRNAs. However, accurate identification of lncRNAs in RNA-seq datasets is crucial for exploring their characteristic functions in the genome as most coding potential computation (CPC) tools fail to accurately identify them in transcriptomic data. Well-known CPC tools such as CPC2, lncScore, CPAT are primarily designed for prediction of lncRNAs based on the GENCODE, NONCODE and CANTATAdb databases. The prediction accuracy of these tools often drops when tested on transcriptomic datasets. This leads to higher false positive results and inaccuracy in the function annotation process. In this study, we present a novel tool, PLIT, for the identification of lncRNAs in plants RNA-seq datasets. PLIT implements a feature selection method based on L1 regularization and iterative Random Forests (iRF) classification for selection of optimal features. Based on sequence and codon-bias features, it classifies the RNA-seq derived FASTA sequences into coding or long non-coding transcripts. Using L1 regularization, 31 optimal features were obtained based on lncRNA and protein-coding transcripts from 8 plant species. The performance of the tool was evaluated on 7 plant RNA-seq datasets using 10-fold cross-validation. The analysis exhibited superior accuracy when evaluated against currently available state-of-the-art CPC tools.

Abstract--In this paper we consider the task of detecting abnormal communication volume occurring at node-level in communication networks. The signal of the communication activity is modeled by means of a clique stream: each occurring communication event is instantaneous and activates an undirected subgraph spanning over a set of equally participating nodes. We present a probabilistic framework to model and assess the communication volume observed at any single node. Specifically, we employ nonparametric regression to learn the probability that a node takes part in a certain event knowing the set of other nodes that are involved. On the top of that, we present a concentration inequality around the estimated volume of events in which a node could participate, which in turn allows us to build an efficient and interpretable anomaly scoring function. Finally, the superior performance of the proposed approach is empirically demonstrated in real-world sensor network data, as well as using synthetic communication activity that is in accordance with that latter setting. I. INTRODUCTION Monitoring the activity in communication networks has become a popular area of research and particular attention has been paid to detection tasks such as spotting events or anomalies. Aneffective way to represent the communication activity is via a dynamic graph where the entities are considered to be nodes, and each communication event (or more simply event) to be represented by a set of connecting edges that appear at a specific time interval.

Real-life mobile phone data may contain noisy instances, which is a fundamental issue for building a prediction model with many potential negative consequences. The complexity of the inferred model may increase, may arise overfitting problem, and thereby the overall prediction accuracy of the model may decrease. In this paper, we address these issues and present a robust prediction model for real-life mobile phone data of individual users, in order to improve the prediction accuracy of the model. In our robust model, we first effectively identify and eliminate the noisy instances from the training dataset by determining a dynamic noise threshold using naive Bayes classifier and laplace estimator, which may differ from user-to-user according to their unique behavioral patterns. After that, we employ the most popular rule-based machine learning classification technique, i.e., decision tree, on the noise-free quality dataset to build the prediction model. Experimental results on the real-life mobile phone datasets (e.g., phone call log) of individual mobile phone users, show the effectiveness of our robust model in terms of precision, recall and f-measure.

Yelp has been one of the most popular local service search engine in US since 2004. It is powered by crowd-sourced text reviews and photo reviews. Restaurant customers and business owners upload photo images to Yelp, including reviewing or advertising either food, drinks, or inside and outside decorations. It is obviously not so effective that labels for food photos rely on human editors, which is an issue should be addressed by innovative machine learning approaches. In this paper, we present a simple but effective approach which can identify up to ten kinds of food via raw photos from the challenge dataset. We use 1) image pre-processing techniques, including filtering and image augmentation, 2) feature extraction via convolutional neural networks (CNN), and 3) three ways of classification algorithms. Then, we illustrate the classification accuracy by tuning parameters for augmentations, CNN, and classification. Our experimental results show this simple but effective approach to identify up to 10 food types from images.

Boosting algorithms [Freund et al., 1996, Friedman et al., 2000, Mason et al., 2000, Friedman, 2001,Bühlmann and Hothorn, 2007] enjoy large popularity in both applied data analysis and machine learning research due to their high predictive accuracy observed on a wide range of data sets [Chen and Guestrin, 2016]. Boosting additively combines base learners by sequentially minimizing a risk functional. To the best of our knowledge, except for one reference [Hothorn et al., 2010], the large majority of boosting algorithms use only one type of functions as base learners. In this article, we relax this assumption by combining trees[Breiman et al., 1984] and reproducing kernel Hilbert space (RKHS) regression functions [Schölkopf and Smola, 2001, Berlinet and Thomas-Agnan, 2011] as base learners, and we empirically show that this combination of different base learners results in increased predictive accuracy compared to both only tree and kernel boosting. To date, regression trees are the most common choice of base learners for boosting in both applied data analysis and machine learning research. In particular, a lot of effort has been made in recent years to develop tree-based boosting methods that scale to large data [Chen and Guestrin, 2016, Ke et al., 2017, Ponomareva et al., 2017, Prokhorenkova et al., 2018]. On the other hand, kernel machines show state-of-the-art predictive accuracy for many data sets as they can, for instance, achieve near-optimal test error [Belkin et al., 2018b,a], and kernel classifiers parallel the behaviors of deep networks as noted in Zhang