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A study of resting-state EEG biomarkers for depression recognition

arXiv.org Machine Learning

Background: Depression has become a major health burden worldwide, and effective detection depression is a great public-health challenge. This Electroencephalography (EEG)-based research is to explore the effective biomarkers for depression recognition. Methods: Resting state EEG data was collected from 24 major depressive patients (MDD) and 29 normal controls using 128 channel HydroCel Geodesic Sensor Net (HCGSN). To better identify depression, we extracted different types of EEG features including linear features, nonlinear features and functional connectivity features phase lagging index (PLI) to comprehensively analyze the EEG signals in patients with MDD. And using different feature selection methods and classifiers to evaluate the optimal feature sets. Results: Functional connectivity feature PLI is superior to the linear features and nonlinear features. And when combining all the types of features to classify MDD patients, we can obtain the highest classification accuracy 82.31% using ReliefF feature selection method and logistic regression (LR) classifier. Analyzing the distribution of optimal feature set, it was found that intrahemispheric connection edges of PLI were much more than the interhemispheric connection edges, and the intrahemispheric connection edges had a significant differences between two groups. Conclusion: Functional connectivity feature PLI plays an important role in depression recognition. Especially, intrahemispheric connection edges of PLI might be an effective biomarker to identify depression. And statistic results suggested that MDD patients might exist functional dysfunction in left hemisphere.


Permutation inference for Canonical Correlation Analysis

arXiv.org Machine Learning

Canonical correlation analysis (CCA) has become a key tool for population neuroimaging for allowing investigation of association between many imaging and non-imaging variables. As age, sex and other variables are often a source of variability not of direct interest, previous work has used CCA on residuals from a model that removes these effects, then proceeded directly to permutation inference. We show that a simple permutation test, as typically used to identify significant modes of shared variation on such data adjusted for nuisance variables, produces inflated error rates. The reason is that residualisation introduces dependencies among the observations that violate the exchangeability assumption. Even in the absence of nuisance variables, however, a simple permutation test for CCA also leads to excess error rates for all canonical correlations other than the first. The reason is that a simple permutation scheme does not ignore the variability already explained by canonical variables of lower rank. Here we propose solutions for both problems: in the case of nuisance variables, we show that projecting the residuals to a lower dimensional space where exchangeability holds results in a valid permutation test; for more general cases, with or without nuisance variables, we propose estimating the canonical correlations in a stepwise manner, removing at each iteration the variance already explained. We also discuss how to address the multiplicity of tests via closure, which leads to an admissible test that is not conservative. We also provide a complete algorithm for permutation inference for CCA.


The Value of Big Data for Credit Scoring: Enhancing Financial Inclusion using Mobile Phone Data and Social Network Analytics

arXiv.org Machine Learning

Credit scoring is without a doubt one of the oldest applications of analytics. In recent years, a multitude of sophisticated classification techniques have been developed to improve the statistical performance of credit scoring models. Instead of focusing on the techniques themselves, this paper leverages alternative data sources to enhance both statistical and economic model performance. The study demonstrates how including call networks, in the context of positive credit information, as a new Big Data source has added value in terms of profit by applying a profit measure and profit-based feature selection. A unique combination of datasets, including call-detail records, credit and debit account information of customers is used to create scorecards for credit card applicants. Call-detail records are used to build call networks and advanced social network analytics techniques are applied to propagate influence from prior defaulters throughout the network to produce influence scores. The results show that combining call-detail records with traditional data in credit scoring models significantly increases their performance when measured in AUC. In terms of profit, the best model is the one built with only calling behavior features. In addition, the calling behavior features are the most predictive in other models, both in terms of statistical and economic performance. The results have an impact in terms of ethical use of call-detail records, regulatory implications, financial inclusion, as well as data sharing and privacy.


12 Supervised Learning Modern Statistics for Modern Biology

#artificialintelligence

In a supervised learning setting, we have a yardstick or plumbline to judge how well we are doing: the response itself. A frequent question in biological and biomedical applications is whether a property of interest (say, disease type, cell type, the prognosis of a patient) can be "predicted", given one or more other properties, called the predictors. Often we are motivated by a situation in which the property to be predicted is unknown (it lies in the future, or is hard to measure), while the predictors are known. The crucial point is that we learn the prediction rule from a set of training data in which the property of interest is also known. Once we have the rule, we can either apply it to new data, and make actual predictions of unknown outcomes; or we can dissect the rule with the aim of better understanding the underlying biology. Compared to unsupervised learning and what we have seen in Chapters 5, 7 and 9, where we do not know what we are looking for or how to decide whether our result is "right", we are on much more solid ground with supervised learning: the objective is clearly stated, and there are straightforward criteria to measure how well we are doing. The central issues in supervised learning151151 Sometimes the term statistical learning is used, more or less exchangeably. Or did our rule indeed pick up some of the pertinent patterns in the system being studied, which will also apply to yet unseen new data? An example for overfitting: two regression lines are fit to data in the \((x, y)\)-plane (black points). We can think of such a line as a rule that predicts the \(y\)-value, given an \(x\)-value. Both lines are smooth, but the fits differ in what is called their bandwidth, which intuitively can be interpreted their stiffness. The blue line seems overly keen to follow minor wiggles in the data, while the orange line captures the general trend but is less detailed. The effective number of parameters needed to describe the blue line is much higher than for the orange line. Also, if we were to obtain additional data, it is likely that the blue line would do a worse job than the orange line in modeling the new data. We'll formalize these concepts โ€“training error and test set errorโ€“ later in this chapter. Although exemplified here with line fitting, the concept applies more generally to prediction models. See exemplary applications that motivate the use of supervised learning methods.


Google launches TensorFlow library for optimizing fairness constraints

#artificialintelligence

Google AI today released TensorFlow Constrained Optimization (TFCO), a supervised machine learning library built for training machine learning models on multiple metrics and "optimizing inequality-constrained problems." The library is designed to help address issues like fairness constraints and predictive parity and help machine learning practitioners better understand things like true positive rates on residents of certain countries, or recall illness diagnoses depending on age and gender. In tests with a Wikipedia data set, the library achieved lower false-positive rates when predicting whether a comment on a Wiki is toxic based on race, religion, gender identity, or sexuality, while maintaining similar accuracy rates. TFCO is made to "take into account the societal and cultural factors necessary to satisfy real-world requirements," said Andrew Zaldivar on behalf of the TFCO team today in a Google AI blog post. "The ability to express many fairness goals as rate constraints can help drive progress in the responsible development of machine learning, but it also requires developers to carefully consider the problem they are trying to address," he said.


How to Develop an Imbalanced Classification Model to Detect Oil Spills

#artificialintelligence

Many imbalanced classification tasks require a skillful model that predicts a crisp class label, where both classes are equally important. An example of an imbalanced classification problem where a class label is required and both classes are equally important is the detection of oil spills or slicks in satellite images. The detection of a spill requires mobilizing an expensive response, and missing an event is equally expensive, causing damage to the environment. One way to evaluate imbalanced classification models that predict crisp labels is to calculate the separate accuracy on the positive class and the negative class, referred to as sensitivity and specificity. These two measures can then be averaged using the geometric mean, referred to as the G-mean, that is insensitive to the skewed class distribution and correctly reports on the skill of the model on both classes. In this tutorial, you will discover how to develop a model to predict the presence of an oil spill in satellite images and evaluate it using the G-mean metric. Develop an Imbalanced Classification Model to Detect Oil Spills Photo by Lenny K Photography, some rights reserved. In this project, we will use a standard imbalanced machine learning dataset referred to as the "oil spill" dataset, "oil slicks" dataset or simply "oil."


Partially Observed Dynamic Tensor Response Regression

arXiv.org Machine Learning

In modern data science, dynamic tensor data is prevailing in numerous applications. An important task is to characterize the relationship between such dynamic tensor and external covariates. However, the tensor data is often only partially observed, rendering many existing methods inapplicable. In this article, we develop a regression model with partially observed dynamic tensor as the response and external covariates as the predictor. We introduce the low-rank, sparsity and fusion structures on the regression coefficient tensor, and consider a loss function projected over the observed entries. We develop an efficient non-convex alternating updating algorithm, and derive the finite-sample error bound of the actual estimator from each step of our optimization algorithm. Unobserved entries in tensor response have imposed serious challenges. As a result, our proposal differs considerably in terms of estimation algorithm, regularity conditions, as well as theoretical properties, compared to the existing tensor completion or tensor response regression solutions. We illustrate the efficacy of our proposed method using simulations, and two real applications, a neuroimaging dementia study and a digital advertising study.



Adversarial Detection and Correction by Matching Prediction Distributions

arXiv.org Machine Learning

We present a novel adversarial detection and correction method for machine learning classifiers.The detector consists of an autoencoder trained with a custom loss function based on the Kullback-Leibler divergence between the classifier predictions on the original and reconstructed instances.The method is unsupervised, easy to train and does not require any knowledge about the underlying attack. The detector almost completely neutralises powerful attacks like Carlini-Wagner or SLIDE on MNIST and Fashion-MNIST, and remains very effective on CIFAR-10 when the attack is granted full access to the classification model but not the defence. We show that our method is still able to detect the adversarial examples in the case of a white-box attack where the attacker has full knowledge of both the model and the defence and investigate the robustness of the attack. The method is very flexible and can also be used to detect common data corruptions and perturbations which negatively impact the model performance. We illustrate this capability on the CIFAR-10-C dataset.


Robust Optimization for Fairness with Noisy Protected Groups

arXiv.org Machine Learning

Many existing fairness criteria for machine learning involve equalizing or achieving some metric across \textit{protected groups} such as race or gender groups. However, practitioners trying to audit or enforce such group-based criteria can easily face the problem of noisy or biased protected group information. We study this important practical problem in two ways. First, we study the consequences of na{\"i}vely only relying on noisy protected groups: we provide an upper bound on the fairness violations on the true groups $G$ when the fairness criteria are satisfied on noisy groups $\hat{G}$. Second, we introduce two new approaches using robust optimization that, unlike the na{\"i}ve approach of only relying on $\hat{G}$, are guaranteed to satisfy fairness criteria on the true protected groups $G$ while minimizing a training objective. We provide theoretical guarantees that one such approach converges to an optimal feasible solution. Using two case studies, we empirically show that the robust approaches achieve better true group fairness guarantees than the na{\"i}ve approach.