Alzheimer's disease is estimated to affect around 50 million people worldwide and is rising rapidly, with a global economic burden of nearly a trillion dollars. This calls for scalable, cost-effective, and robust methods for detection of Alzheimer's dementia (AD). We present a novel architecture that leverages acoustic, cognitive, and linguistic features to form a multimodal ensemble system. It uses specialized artificial neural networks with temporal characteristics to detect AD and its severity, which is reflected through Mini-Mental State Exam (MMSE) scores. We first evaluate it on the ADReSS challenge dataset, which is a subject-independent and balanced dataset matched for age and gender to mitigate biases, and is available through DementiaBank. Our system achieves state-of-the-art test accuracy, precision, recall, and F1-score of 83.3% each for AD classification, and state-of-the-art test root mean squared error (RMSE) of 4.60 for MMSE score regression. To the best of our knowledge, the system further achieves state-of-the-art AD classification accuracy of 88.0% when evaluated on the full benchmark DementiaBank Pitt database. Our work highlights the applicability and transferability of spontaneous speech to produce a robust inductive transfer learning model, and demonstrates generalizability through a task-agnostic feature-space. The source code is available at https://github.com/wazeerzulfikar/alzheimers-dementia

Software testing is one of the important ways to ensure the quality of software. It is found that testing cost more than 50% of overall project cost. Effective and efficient software testing utilizes the minimum resources of software. Therefore, it is important to construct the procedure which is not only able to perform the efficient testing but also minimizes the utilization of project resources. The goal of software testing is to find maximum defects in the software system. More the defects found in the software ensure more efficiency is the software testing Different techniques have been proposed to detect the defects in software and to utilize the resources and achieve good results. As world is continuously moving toward data driven approach for making important decision. Therefore, in this research paper we performed the machine learning analysis on the publicly available datasets and tried to achieve the maximum accuracy. The major focus of the paper is to apply different machine learning techniques on the datasets and find out which technique produce efficient result. Particularly, we proposed an ensemble learning models and perform comparative analysis among KNN, Decision tree, SVM and Na\"ive Bayes on different datasets and it is demonstrated that performance of Ensemble method is more than other methods in term of accuracy, precision, recall and F1-score. The classification accuracy of ensemble model trained on CM1 is 98.56%, classification accuracy of ensemble model trained on KM2 is 98.18% similarly, the classification accuracy of ensemble learning model trained on PC1 is 99.27%. This reveals that Ensemble is more efficient method for making the defect prediction as compared other techniques.

We propose a novel Neyman-Pearson (NP) classifier that is both online and nonlinear as the first time in the literature. The proposed classifier operates on a binary labeled data stream in an online manner, and maximizes the detection power about a user-specified and controllable false positive rate. Our NP classifier is a single hidden layer feedforward neural network (SLFN), which is initialized with random Fourier features (RFFs) to construct the kernel space of the radial basis function at its hidden layer with sinusoidal activation. Not only does this use of RFFs provide an excellent initialization with great nonlinear modeling capability, but it also exponentially reduces the parameter complexity and compactifies the network to mitigate overfitting while improving the processing efficiency substantially. We sequentially learn the SLFN with stochastic gradient descent updates based on a Lagrangian NP objective. As a result, we obtain an expedited online adaptation and powerful nonlinear Neyman-Pearson modeling. Our algorithm is appropriate for large scale data applications and provides a decent false positive rate controllability with real time processing since it only has O(N) computational and O(1) space complexity (N: number of data instances). In our extensive set of experiments on several real datasets, our algorithm is highly superior over the competing state-of-the-art techniques, either by outperforming in terms of the NP classification objective with a comparable computational as well as space complexity or by achieving a comparable performance with significantly lower complexity. Designing a binary classifier with asymmetrical costs for the errors of type I (false positive) and type II (false negative) [1]-[3], or equivalently designing a Neyman-Pearson classifier [4], is required in various applications ranging from facial age estimation [5], multi-view learning [6] and software defect prediction [7] to video surveillance [8] and data imputation [9]. For example, in medical diagnostics, type II error (misdiagnosing as healthy) has perhaps more severe consequences, whereas type I error (misdiagnosing as unhealthy) may result in devastating psychological effects [10].

Energy theft causes large economic losses to utility companies around the world. In recent years, energy theft detection approaches based on machine learning (ML) techniques, especially neural networks, become popular in the research literature and achieve state-of-the-art detection performance. However, in this work, we demonstrate that the well-perform ML models for energy theft detection are highly vulnerable to adversarial attacks. In particular, we design an adversarial measurement generation algorithm that enables the attacker to report extremely low power consumption measurements to the utilities while bypassing the ML energy theft detection. We evaluate our approach with three kinds of neural networks based on a real-world smart meter dataset. The evaluation result demonstrates that our approach can significantly decrease the ML models' detection accuracy, even for black-box attackers.

Federated learning platforms are gaining popularity. One of the major benefits is to mitigate the privacy risks as the learning of algorithms can be achieved without collecting or sharing data. While federated learning (i.e., many based on stochastic gradient algorithms) has shown great promise, there are still many challenging problems in protecting privacy, especially during the process of gradients update and exchange. This paper presents the first gradient-free federated learning framework called GRAFFL for learning a Bayesian generative model based on approximate Bayesian computation. Unlike conventional federated learning algorithms based on gradients, our framework does not require to disassemble a model (i.e., to linear components) or to perturb data (or encryption of data for aggregation) to preserve privacy. Instead, this framework uses implicit information derived from each participating institution to learn posterior distributions of parameters. The implicit information is summary statistics derived from SuffiAE that is a neural network developed in this study to create compressed and linearly separable representations thereby protecting sensitive information from leakage. As a sufficient dimensionality reduction technique, this is proved to provide sufficient summary statistics. We propose the GRAFFL-based Bayesian Gaussian mixture model to serve as a proof-of-concept of the framework. Using several datasets, we demonstrated the feasibility and usefulness of our model in terms of privacy protection and prediction performance (i.e., close to an ideal setting). The trained model as a quasi-global model can generate informative samples involving information from other institutions and enhances data analysis of each institution.

In the information age, a secure and stable network environment is essential and hence intrusion detection is critical for any networks. In this paper, we propose a self-organizing map assisted deep autoencoding Gaussian mixture model (SOMDAGMM) supplemented with well-preserved input space topology for more accurate network intrusion detection. The deep autoencoding Gaussian mixture model comprises a compression network and an estimation network which is able to perform unsupervised joint training. However, the code generated by the autoencoder is inept at preserving the topology of the input space, which is rooted in the bottleneck of the adopted deep structure. A self-organizing map has been introduced to construct SOMDAGMM for addressing this issue. The superiority of the proposed SOM-DAGMM is empirically demonstrated with extensive experiments conducted upon two datasets. Experimental results show that SOM-DAGMM outperforms state-of-the-art DAGMM on all tests, and achieves up to 15.58% improvement in F1 score and with better stability.

We move beyond "Is Machine Learning Useful for Macroeconomic Forecasting?" by adding the "how". The current forecasting literature has focused on matching specific variables and horizons with a particularly successful algorithm. In contrast, we study the usefulness of the underlying features driving ML gains over standard macroeconometric methods. We distinguish four so-called features (nonlinearities, regularization, cross-validation and alternative loss function) and study their behavior in both the data-rich and data-poor environments. To do so, we design experiments that allow to identify the "treatment" effects of interest. We conclude that (i) nonlinearity is the true game changer for macroeconomic prediction, (ii) the standard factor model remains the best regularization, (iii) K-fold cross-validation is the best practice and (iv) the $L_2$ is preferred to the $\bar \epsilon$-insensitive in-sample loss. The forecasting gains of nonlinear techniques are associated with high macroeconomic uncertainty, financial stress and housing bubble bursts. This suggests that Machine Learning is useful for macroeconomic forecasting by mostly capturing important nonlinearities that arise in the context of uncertainty and financial frictions.

Phishing attacks have been causing havoc for many years. They are becoming an increasing concern around the world. Though earlier, there were only phishing email scams now, we see a massive uptick in the frequency of internal and lateral phishing attacks. As per Verizon's 2020 Data Breach Investigations Report (DBIR), 22 percent of breaches in 2019, involved phishing. Meanwhile, according to APWG's Phishing Activity Trends Report for Q1 2020, phishing attacks rose in prevalence to a level that hasn't been observed since 2016, with over 60,000 phishing sites being reported in March alone.

Dota 2 is a popular, multiplayer online video game. Like many online games, players are mostly anonymous, being tied only to online accounts which can be readily obtained, sold and shared between multiple people. This makes it difficult to track or ban players who exhibit unwanted behavior online. In this paper, we present a machine learning approach to identify players based a `digital fingerprint' of how they play the game, rather than by account. We use data on mouse movements, in-game statistics and game strategy extracted from match replays and show that for best results, all of these are necessary. We are able to obtain an accuracy of prediction of 95\% for the problem of predicting if two different matches were played by the same player.

Medical diagnoses can shape and change the life of a person drastically. Therefore, it is always best advised to collect as much evidence as possible to be certain about the diagnosis. Unfortunately, in the case of the Brugada Syndrome (BrS), a rare and inherited heart disease, only one diagnostic criterion exists, namely, a typical pattern in the Electrocardiogram (ECG). In the following treatise, we question whether the investigation of ECG strips by the means of machine learning methods improves the detection of BrS positive cases and hence, the diagnostic process. We propose a pipeline that reads in scanned images of ECGs, and transforms the encaptured signals to digital time-voltage data after several processing steps. Then, we present a long short-term memory (LSTM) classifier that is built based on the previously extracted data and that makes the diagnosis. The proposed pipeline distinguishes between three major types of ECG images and recreates each recorded lead signal. Features and quality are retained during the digitization of the data, albeit some encountered issues are not fully removed (Part I). Nevertheless, the results of the aforesaid program are suitable for further investigation of the ECG by a computational method such as the proposed classifier which proves the concept and could be the architectural basis for future research (Part II). This thesis is divided into two parts as they are part of the same process but conceptually different. It is hoped that this work builds a new foundation for computational investigations in the case of the BrS and its diagnosis.