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NLP Methods for Extraction of Symptoms from Unstructured Data for Use in Prognostic COVID-19 Analytic Models

Journal of Artificial Intelligence Research

Statistical modeling of outcomes based on a patient's presenting symptoms (symptomatology) can help deliver high quality care and allocate essential resources, which is especially important during the COVID-19 pandemic. Patient symptoms are typically found in unstructured notes, and thus not readily available for clinical decision making. In an attempt to fill this gap, this study compared two methods for symptom extraction from Emergency Department (ED) admission notes. Both methods utilized a lexicon derived by expanding The Center for Disease Control and Prevention's (CDC) Symptoms of Coronavirus list. The first method utilized a word2vec model to expand the lexicon using a dictionary mapping to the Uni ed Medical Language System (UMLS). The second method utilized the expanded lexicon as a rule-based gazetteer and the UMLS. These methods were evaluated against a manually annotated reference (f1-score of 0.87 for UMLS-based ensemble; and 0.85 for rule-based gazetteer with UMLS). Through analyses of associations of extracted symptoms used as features against various outcomes, salient risks among the population of COVID-19 patients, including increased risk of in-hospital mortality (OR 1.85, p-value < 0.001), were identified for patients presenting with dyspnea. Disparities between English and non-English speaking patients were also identified, the most salient being a concerning finding of opposing risk signals between fatigue and in-hospital mortality (non-English: OR 1.95, p-value = 0.02; English: OR 0.63, p-value = 0.01). While use of symptomatology for modeling of outcomes is not unique, unlike previous studies this study showed that models built using symptoms with the outcome of in-hospital mortality were not significantly different from models using data collected during an in-patient encounter (AUC of 0.9 with 95% CI of [0.88, 0.91] using only vital signs; AUC of 0.87 with 95% CI of [0.85, 0.88] using only symptoms). These findings indicate that prognostic models based on symptomatology could aid in extending COVID-19 patient care through telemedicine, replacing the need for in-person options. The methods presented in this study have potential for use in development of symptomatology-based models for other diseases, including for the study of Post-Acute Sequelae of COVID-19 (PASC).


Continuous Authentication Using Mouse Movements, Machine Learning, and Minecraft

arXiv.org Artificial Intelligence

Mouse dynamics has grown in popularity as a novel irreproducible behavioral biometric. Datasets which contain general unrestricted mouse movements from users are sparse in the current literature. The Balabit mouse dynamics dataset produced in 2016 was made for a data science competition and despite some of its shortcomings, is considered to be the first publicly available mouse dynamics dataset. Collecting mouse movements in a dull administrative manner as Balabit does may unintentionally homogenize data and is also not representative of realworld application scenarios. This paper presents a novel mouse dynamics dataset that has been collected while 10 users play the video game Minecraft on a desktop computer. Binary Random Forest (RF) classifiers are created for each user to detect differences between a specific users movements and an imposters movements. Two evaluation scenarios are proposed to evaluate the performance of these classifiers; one scenario outperformed previous works in all evaluation metrics, reaching average accuracy rates of 92%, while the other scenario successfully reported reduced instances of false authentications of imposters.


Multi-task problems are not multi-objective

arXiv.org Machine Learning

Multi-objective optimization (MOO) aims at finding a set of optimal configurations for a given set of objectives. A recent line of work applies MOO methods to the typical Machine Learning (ML) setting, which becomes multi-objective if a model should optimize more than one objective, for instance in fair machine learning. These works also use Multi-Task Learning (MTL) problems to benchmark MOO algorithms treating each task as independent objective. In this work we show that MTL problems do not resemble the characteristics of MOO problems. In particular, MTL losses are not competing in case of a sufficiently expressive single model. As a consequence, a single model can perform just as well as optimizing all objectives with independent models, rendering MOO inapplicable. We provide evidence with extensive experiments on the widely used Multi-Fashion-MNIST datasets. Our results call for new benchmarks to evaluate MOO algorithms for ML. Our code is available at: https://github.com/ruchtem/moo-mtl.


Learn then Test: Calibrating Predictive Algorithms to Achieve Risk Control

arXiv.org Machine Learning

We introduce Learn then Test, a framework for calibrating machine learning models so that their predictions satisfy explicit, finite-sample statistical guarantees regardless of the underlying model and (unknown) data-generating distribution. The framework addresses, among other examples, false discovery rate control in multi-label classification, intersection-over-union control in instance segmentation, and the simultaneous control of the type-1 error of outlier detection and confidence set coverage in classification or regression. To accomplish this, we solve a key technical challenge: the control of arbitrary risks that are not necessarily monotonic. Our main insight is to reframe the risk-control problem as multiple hypothesis testing, enabling techniques and mathematical arguments different from those in the previous literature. We use our framework to provide new calibration methods for several core machine learning tasks with detailed worked examples in computer vision.


ML for Security Is Dead. Long Live ML for Security

#artificialintelligence

When it comes to staying on top of security threats, machine learning, unquestionably, must be part of the equation. The volume of data is simply too great to cope without it. But as it's currently being used, ML may be doing more harm than good, particularly when it comes to alarm fatigue. Alarm fatigue is a condition that occurs when an operator is overloaded with alarms; in many of these cases, the majority of alarms turn out to be false positives. With too many alarms to investigate in a limited amount of time–and the knowledge that most of them are false positives–the operator begins to ignore some alarms, which invariably leads to bad outcomes.


E-Commerce Dispute Resolution Prediction

arXiv.org Artificial Intelligence

E-Commerce marketplaces support millions of daily transactions, and some disagreements between buyers and sellers are unavoidable. Resolving disputes in an accurate, fast, and fair manner is of great importance for maintaining a trustworthy platform. Simple cases can be automated, but intricate cases are not sufficiently addressed by hard-coded rules, and therefore most disputes are currently resolved by people. In this work we take a first step towards automatically assisting human agents in dispute resolution at scale. We construct a large dataset of disputes from the eBay online marketplace, and identify several interesting behavioral and linguistic patterns. We then train classifiers to predict dispute outcomes with high accuracy. We explore the model and the dataset, reporting interesting correlations, important features, and insights.


Ego4D: Around the World in 3,000 Hours of Egocentric Video

arXiv.org Artificial Intelligence

We introduce Ego4D, a massive-scale egocentric video dataset and benchmark suite. It offers 3,025 hours of daily-life activity video spanning hundreds of scenarios (household, outdoor, workplace, leisure, etc.) captured by 855 unique camera wearers from 74 worldwide locations and 9 different countries. The approach to collection is designed to uphold rigorous privacy and ethics standards with consenting participants and robust de-identification procedures where relevant. Ego4D dramatically expands the volume of diverse egocentric video footage publicly available to the research community. Portions of the video are accompanied by audio, 3D meshes of the environment, eye gaze, stereo, and/or synchronized videos from multiple egocentric cameras at the same event. Furthermore, we present a host of new benchmark challenges centered around understanding the first-person visual experience in the past (querying an episodic memory), present (analyzing hand-object manipulation, audio-visual conversation, and social interactions), and future (forecasting activities). By publicly sharing this massive annotated dataset and benchmark suite, we aim to push the frontier of first-person perception. Project page: https://ego4d-data.org/


HEDP: A Method for Early Forecasting Software Defects based on Human Error Mechanisms

arXiv.org Artificial Intelligence

As the primary cause of software defects, human error is the key to understanding, and perhaps to predicting and avoiding them. Little research has been done to predict defects on the basis of the cognitive errors that cause them. This paper proposes an approach to predicting software defects through knowledge about the cognitive mechanisms of human errors. Our theory is that the main process behind a software defect is that an error-prone scenario triggers human error modes, which psychologists have observed to recur across diverse activities. Software defects can then be predicted by identifying such scenarios, guided by this knowledge of typical error modes. The proposed idea emphasizes predicting the exact location and form of a possible defect. We conducted two case studies to demonstrate and validate this approach, with 55 programmers in a programming competition and 5 analysts serving as the users of the approach. We found it impressive that the approach was able to predict, at the requirement phase, the exact locations and forms of 7 out of the 22 (31.8%) specific types of defects that were found in the code. The defects predicted tended to be common defects: their occurrences constituted 75.7% of the total number of defects in the 55 developed programs; each of them was introduced by at least two persons. The fraction of the defects introduced by a programmer that were predicted was on average (over all programmers) 75%. Furthermore, these predicted defects were highly persistent through the debugging process. If the prediction had been used to successfully prevent these defects, this could have saved 46.2% of the debugging iterations. This excellent capability of forecasting the exact locations and forms of possible defects at the early phases of software development recommends the approach for substantial benefits to defect prevention and early detection.


Logic Constraints to Feature Importances

arXiv.org Machine Learning

In recent years, Artificial Intelligence (AI) algorithms have been proven to outperform traditional statistical methods in terms of predictivity, especially when a large amount of data was available. Nevertheless, the "black box" nature of AI models is often a limit for a reliable application in high-stakes fields like diagnostic techniques, autonomous guide, etc. Recent works have shown that an adequate level of interpretability could enforce the more general concept of model trustworthiness. The basic idea of this paper is to exploit the human prior knowledge of the features' importance for a specific task, in order to coherently aid the phase of the model's fitting. This sort of "weighted" AI is obtained by extending the empirical loss with a regularization term encouraging the importance of the features to follow predetermined constraints. This procedure relies on local methods for the feature importance computation, e.g. LRP, LIME, etc. that are the link between the model weights to be optimized and the user-defined constraints on feature importance. In the fairness area, promising experimental results have been obtained for the Adult dataset. Many other possible applications of this model agnostic theoretical framework are described.


COVID-19 rapid test national shortage mobilizes White House, leaves experts cautiously optimistic

FOX News

Fox News Flash top headlines are here. Check out what's clicking on Foxnews.com. Last week's White House report reiterated President Biden's employer mandate that businesses with 100 or more employees require every worker to be fully vaccinated for COVID-19 or tested weekly. Jeffrey Zients, the White House COVID-19 response coordinator, summarized in last week's press briefing that, "We are on track to quadruple the supply of rapid, at-home tests available to Americans by December to more than 200 million a month and to increase the number of places Americans can access free testing in the United States to 30,000 community-based locations." He emphasized the president's staunch commitment in adding $1 billion of extra funding already to the recent $2 billion investment to increase supply.