Medical coding is a complex task, requiring assignment of a subset of over 72,000 ICD codes to a patient's notes. Modern natural language processing approaches to these tasks have been challenged by the length of the input and size of the output space. We limit our model inputs to a small window around medical entities found in our documents. From those local contexts, we build contextualized representations of both ICD codes and entities, and aggregate over these representations to form document-level predictions. In contrast to existing methods which use a representation fixed either in size or by codes seen in training, we represent ICD codes by encoding the code description with local context. We discuss metrics appropriate to deploying coding systems in practice. We show that our approach is superior to existing methods in both standard and deployable measures, including performance on rare and unseen codes. 1 Introduction Medical coding is the complex task aimed at generating a coded summary of clinical information associated with a patient.

Inferring linear relationships lies at the heart of many empirical investigations. A measure of linear dependence should correctly evaluate the strength of the relationship as well as qualify whether it is meaningful for the population. Pearson's correlation coefficient (PCC), the \textit{de-facto} measure for bivariate relationships, is known to lack in both regards. The estimated strength $r$ maybe wrong due to limited sample size, and nonnormality of data. In the context of statistical significance testing, erroneous interpretation of a $p$-value as posterior probability leads to Type I errors -- a general issue with significance testing that extends to PCC. Such errors are exacerbated when testing multiple hypotheses simultaneously. To tackle these issues, we propose a machine-learning-based predictive data calibration method which essentially conditions the data samples on the expected linear relationship. Calculating PCC using calibrated data yields a calibrated $p$-value that can be interpreted as posterior probability together with a calibrated $r$ estimate, a desired outcome not provided by other methods. Furthermore, the ensuing independent interpretation of each test might eliminate the need for multiple testing correction. We provide empirical evidence favouring the proposed method using several simulations and application to real-world data.

Recently, adapting the idea of self-supervised learning (SSL) on continuous speech has started gaining attention. SSL models pre-trained on a huge amount of unlabeled audio can generate general-purpose representations that benefit a wide variety of speech processing tasks. Despite their ubiquitous deployment, however, the potential privacy risks of these models have not been well investigated. In this paper, we present the first privacy analysis on several SSL speech models using Membership Inference Attacks (MIA) under black-box access. The experiment results show that these pre-trained models are vulnerable to MIA and prone to membership information leakage with high Area Under the Curve (AUC) in both utterance-level and speaker-level. Furthermore, we also conduct several ablation studies to understand the factors that contribute to the success of MIA.

ML practitioners often explore image datasets by generating a grid of images or projecting high-dimensional representations of images into 2-D using dimensionality reduction techniques (e.g., t-SNE). However, neither approach effectively scales to large datasets because images are ineffectively organized and interactions are insufficiently supported. To address these challenges, we develop DendroMap by adapting Treemaps, a well-known visualization technique. DendroMap effectively organizes images by extracting hierarchical cluster structures from high-dimensional representations of images. It enables users to make sense of the overall distributions of datasets and interactively zoom into specific areas of interests at multiple levels of abstraction. Our case studies with widely-used image datasets for deep learning demonstrate that users can discover insights about datasets and trained models by examining the diversity of images, identifying underperforming subgroups, and analyzing classification errors. We conducted a user study that evaluates the effectiveness of DendroMap in grouping and searching tasks by comparing it with a gridified version of t-SNE and found that participants preferred DendroMap.

Malware is a major threat to computer systems and imposes many challenges to cyber security. Targeted threats, such as ransomware, cause millions of dollars in losses every year. The constant increase of malware infections has been motivating popular antiviruses (AVs) to develop dedicated detection strategies, which include meticulously crafted machine learning (ML) pipelines. However, malware developers unceasingly change their samples' features to bypass detection. This constant evolution of malware samples causes changes to the data distribution (i.e., concept drifts) that directly affect ML model detection rates, something not considered in the majority of the literature work. In this work, we evaluate the impact of concept drift on malware classifiers for two Android datasets: DREBIN (about 130K apps) and a subset of AndroZoo (about 285K apps). We used these datasets to train an Adaptive Random Forest (ARF) classifier, as well as a Stochastic Gradient Descent (SGD) classifier. We also ordered all datasets samples using their VirusTotal submission timestamp and then extracted features from their textual attributes using two algorithms (Word2Vec and TF-IDF). Then, we conducted experiments comparing both feature extractors, classifiers, as well as four drift detectors (DDM, EDDM, ADWIN, and KSWIN) to determine the best approach for real environments. Finally, we compare some possible approaches to mitigate concept drift and propose a novel data stream pipeline that updates both the classifier and the feature extractor. To do so, we conducted a longitudinal evaluation by (i) classifying malware samples collected over nine years (2009-2018), (ii) reviewing concept drift detection algorithms to attest its pervasiveness, (iii) comparing distinct ML approaches to mitigate the issue, and (iv) proposing an ML data stream pipeline that outperformed literature approaches.

Multi-instance learning (MIL) is widely used in the computer-aided interpretation of pathological Whole Slide Images (WSIs) to solve the lack of pixel-wise or patch-wise annotations. Often, this approach directly applies "natural image driven" MIL algorithms which overlook the multi-scale (i.e. pyramidal) nature of WSIs. Off-the-shelf MIL algorithms are typically deployed on a single-scale of WSIs (e.g., 20x magnification), while human pathologists usually aggregate the global and local patterns in a multi-scale manner (e.g., by zooming in and out between different magnifications). In this study, we propose a novel cross-scale attention mechanism to explicitly aggregate inter-scale interactions into a single MIL network for Crohn's Disease (CD), which is a form of inflammatory bowel disease. The contribution of this paper is two-fold: (1) a cross-scale attention mechanism is proposed to aggregate features from different resolutions with multi-scale interaction; and (2) differential multi-scale attention visualizations are generated to localize explainable lesion patterns. By training ~250,000 H&E-stained Ascending Colon (AC) patches from 20 CD patient and 30 healthy control samples at different scales, our approach achieved a superior Area under the Curve (AUC) score of 0.8924 compared with baseline models. The official implementation is publicly available at https://github.com/hrlblab/CS-MIL.

Many recent approaches in contrastive learning have worked to close the gap between pretraining on iconic images like ImageNet and pretraining on complex scenes like COCO. This gap exists largely because commonly used random crop augmentations obtain semantically inconsistent content in crowded scene images of diverse objects. Previous works use preprocessing pipelines to localize salient objects for improved cropping, but an end-to-end solution is still elusive. In this work, we propose a framework which accomplishes this goal via joint learning of representations and segmentation. We leverage segmentation masks to train a model with a mask-dependent contrastive loss, and use the partially trained model to bootstrap better masks. By iterating between these two components, we ground the contrastive updates in segmentation information, and simultaneously improve segmentation throughout pretraining. Experiments show our representations transfer robustly to downstream tasks in classification, detection and segmentation.

Centuries are a celebrated event in cricket, usually resulting in match-winning innings by the batsman. As a statistics enthusiast, it felt like a great problem to model because it is not only immensely interesting, the novelty of the problem did make it challenging. This piece explains the reasoning behind how I prepared the data, what model I used, and the evaluation criteria. In a previous post, I did a probabilistic analysis of centuries, a key finding was that unconditioned on anything else, the empirically estimated probability of a batsman knock resulting in a century is only 3.16%. This is important because when modeling a classification problem, class prevalence is probably the most crucial factor in determining the efficacy of your model(s).

Despite being high dimensional, physics datasets are highly structured since physical laws strictly govern the data generating process. Although the data is complicated, it is not hard to imagine that physics data can exist within low-dimensional manifolds inside a high-dimensional ambient space. There is a growing recent interest in endowing the space of collider events with a metric structure calculated directly in the space of its inputs. Metrics based on optimal transport, such as energy mover's distance (EMD) [1] and Hellinger distance [2], allow us to compare raw inputs directly and quantify the global structural difference between any pair of collider events. Since the advent of these studies, a broad range of use cases has been emerging for these metrics. These include event tagging, anomaly tagging[3-5], and measurements of Quantum Chromo Dynamical (QCD) properties. However, the input dimension is usually very large for collider data; thus, the induced manifold of the metric lives in a very high dimensional space, making it challenging to work with directly.

Federated learning offers a framework of training a machine learning model in a distributed fashion while preserving privacy of the participants. As the server cannot govern the clients' actions, nefarious clients may attack the global model by sending malicious local gradients. In the meantime, there could also be unreliable clients who are benign but each has a portion of low-quality training data (e.g., blur or low-resolution images), thus may appearing similar as malicious clients. Therefore, a defense mechanism will need to perform a three-fold differentiation which is much more challenging than the conventional (two-fold) case. This paper introduces MUD-HoG, a novel defense algorithm that addresses this challenge in federated learning using long-short history of gradients, and treats the detected malicious and unreliable clients differently. Not only this, but we can also distinguish between targeted and untargeted attacks among malicious clients, unlike most prior works which only consider one type of the attacks. Specifically, we take into account sign-flipping, additive-noise, label-flipping, and multi-label-flipping attacks, under a non-IID setting. We evaluate MUD-HoG with six state-of-the-art methods on two datasets. The results show that MUD-HoG outperforms all of them in terms of accuracy as well as precision and recall, in the presence of a mixture of multiple (four) types of attackers as well as unreliable clients. Moreover, unlike most prior works which can only tolerate a low population of harmful users, MUD-HoG can work with and successfully detect a wide range of malicious and unreliable clients - up to 47.5% and 10%, respectively, of the total population. Our code is open-sourced at https://github.com/LabSAINT/MUD-HoG_Federated_Learning.