Liver transplant is an essential therapy performed for severe liver diseases. The fact of scarce liver resources makes the organ assigning crucial. Model for End-stage Liver Disease (MELD) score is a widely adopted criterion when making organ distribution decisions. However, it ignores post-transplant outcomes and organ/donor features. These limitations motivate the emergence of machine learning (ML) models. Unfortunately, ML models could be unfair and trigger bias against certain groups of people. To tackle this problem, this work proposes a fair machine learning framework targeting graft failure prediction in liver transplant. Specifically, knowledge distillation is employed to handle dense and sparse features by combining the advantages of tree models and neural networks. A two-step debiasing method is tailored for this framework to enhance fairness. Experiments are conducted to analyze unfairness issues in existing models and demonstrate the superiority of our method in both prediction and fairness performance.

When designing Machine Learning (ML) enabled solutions, designers often need to simulate ML behavior through the Wizard of Oz (WoZ) approach to test the user experience before the ML model is available. Although reproducing ML errors is essential for having a good representation, they are rarely considered. We introduce Wizard of Errors (WoE), a tool for conducting WoZ studies on ML-enabled solutions that allows simulating ML errors during user experience assessment. We explored how this system can be used to simulate the behavior of a computer vision model. We tested WoE with design students to determine the importance of considering ML errors in design, the relevance of using descriptive error types instead of confusion matrix, and the suitability of manual error control in WoZ studies. Our work identifies several challenges, which prevent realistic error representation by designers in such studies. We discuss the implications of these findings for design.

To mitigate the effects of undesired biases in models, several approaches propose to pre-process the input dataset to reduce the risks of discrimination by preventing the inference of sensitive attributes. Unfortunately, most of these pre-processing methods lead to the generation a new distribution that is very different from the original one, thus often leading to unrealistic data. As a side effect, this new data distribution implies that existing models need to be re-trained to be able to make accurate predictions. To address this issue, we propose a novel pre-processing method, that we coin as fair mapping, based on the transformation of the distribution of protected groups onto a chosen target one, with additional privacy constraints whose objective is to prevent the inference of sensitive attributes. More precisely, we leverage on the recent works of the Wasserstein GAN and AttGAN frameworks to achieve the optimal transport of data points coupled with a discriminator enforcing the protection against attribute inference. Our proposed approach, preserves the interpretability of data and can be used without defining exactly the sensitive groups. In addition, our approach can be specialized to model existing state-of-the-art approaches, thus proposing a unifying view on these methods. Finally, several experiments on real and synthetic datasets demonstrate that our approach is able to hide the sensitive attributes, while limiting the distortion of the data and improving the fairness on subsequent data analysis tasks.

In this paper we revisit the bias-variance decomposition of model error from the perspective of designing a fair classifier: we are motivated by the widely held socio-technical belief that noise variance in large datasets in social domains tracks demographic characteristics such as gender, race, disability, etc. We propose a conditional-iid (ciid) model built from group-specific classifiers that seeks to improve on the trade-offs made by a single model (iid setting). We theoretically analyze the bias-variance decomposition of different models in the Gaussian Mixture Model, and then empirically test our setup on the COMPAS and folktables datasets. We instantiate the ciid model with two procedures that improve "fairness" by conditioning out undesirable effects: first, by conditioning directly on sensitive attributes, and second, by clustering samples into groups and conditioning on cluster membership (blind to protected group membership). Our analysis suggests that there might be principled procedures and concrete real-world use cases under which conditional models are preferred, and our striking empirical results strongly indicate that non-iid settings, such as the ciid setting proposed here, might be more suitable for big data applications in social contexts.

Patients with the COVID-19 infection may have pneumonia-like symptoms as well as respiratory problems which may harm the lungs. From medical images, coronavirus illness may be accurately identified and predicted using a variety of machine learning methods. Most of the published machine learning methods may need extensive hyperparameter adjustment and are unsuitable for small datasets. By leveraging the data in a comparatively small dataset, few-shot learning algorithms aim to reduce the requirement of large datasets. This inspired us to develop a few-shot learning model for early detection of COVID-19 to reduce the post-effect of this dangerous disease. The proposed architecture combines few-shot learning with an ensemble of pre-trained convolutional neural networks to extract feature vectors from CT scan images for similarity learning. The proposed Triplet Siamese Network as the few-shot learning model classified CT scan images into Normal, COVID-19, and Community-Acquired Pneumonia. The suggested model achieved an overall accuracy of 98.719%, a specificity of 99.36%, a sensitivity of 98.72%, and a ROC score of 99.9% with only 200 CT scans per category for training data.

Ensuring trustworthiness in machine learning (ML) models is a multi-dimensional task. In addition to the traditional notion of predictive performance, other notions such as privacy, fairness, robustness to distribution shift, adversarial robustness, interpretability, explainability, and uncertainty quantification are important considerations to evaluate and improve (if deficient). However, these sub-disciplines or 'pillars' of trustworthiness have largely developed independently, which has limited us from understanding their interactions in real-world ML pipelines. In this paper, focusing specifically on compositions of functions arising from the different pillars, we aim to reduce this gap, develop new insights for trustworthy ML, and answer questions such as the following. Does the composition of multiple fairness interventions result in a fairer model compared to a single intervention? How do bias mitigation algorithms for fairness affect local post-hoc explanations? Does a defense algorithm for untargeted adversarial attacks continue to be effective when composed with a privacy transformation? Toward this end, we report initial empirical results and new insights from 9 different compositions of functions (or pipelines) on 7 real-world datasets along two trustworthy dimensions - fairness and explainability. We also report progress, and implementation choices, on an extensible composer tool to encourage the combination of functionalities from multiple pillars. To-date, the tool supports bias mitigation algorithms for fairness and post-hoc explainability methods. We hope this line of work encourages the thoughtful consideration of multiple pillars when attempting to formulate and resolve a trustworthiness problem.

Predictive algorithms are now used to help distribute a large share of our society's resources and sanctions, such as healthcare, loans, criminal detentions, and tax audits. Under the right circumstances, these algorithms can improve the efficiency and equity of decision-making. At the same time, there is a danger that the algorithms themselves could entrench and exacerbate disparities, particularly along racial, ethnic, and gender lines. To help ensure their fairness, many researchers suggest that algorithms be subject to at least one of three constraints: (1) no use of legally protected features, such as race, ethnicity, and gender; (2) equal rates of "positive" decisions across groups; and (3) equal error rates across groups. Here we show that these constraints, while intuitively appealing, often worsen outcomes for individuals in marginalized groups, and can even leave all groups worse off. The inherent trade-off we identify between formal fairness constraints and welfare improvements -- particularly for the marginalized -- highlights the need for a more robust discussion on what it means for an algorithm to be "fair". We illustrate these ideas with examples from healthcare and the criminal-legal system, and make several proposals to help practitioners design more equitable algorithms.

A multitude of work has shown that machine learning-based medical diagnosis systems can be biased against certain subgroups of people. This has motivated a growing number of bias mitigation algorithms that aim to address fairness issues in machine learning. However, it is difficult to compare their effectiveness in medical imaging for two reasons. First, there is little consensus on the criteria to assess fairness. Second, existing bias mitigation algorithms are developed under different settings, e.g., datasets, model selection strategies, backbones, and fairness metrics, making a direct comparison and evaluation based on existing results impossible. In this work, we introduce MEDFAIR, a framework to benchmark the fairness of machine learning models for medical imaging. MEDFAIR covers eleven algorithms from various categories, nine datasets from different imaging modalities, and three model selection criteria. Through extensive experiments, we find that the under-studied issue of model selection criterion can have a significant impact on fairness outcomes; while in contrast, state-of-the-art bias mitigation algorithms do not significantly improve fairness outcomes over empirical risk minimization (ERM) in both in-distribution and out-of-distribution settings. We evaluate fairness from various perspectives and make recommendations for different medical application scenarios that require different ethical principles. Our framework provides a reproducible and easy-to-use entry point for the development and evaluation of future bias mitigation algorithms in deep learning. Code is available at https://github.com/ys-zong/MEDFAIR.

Partial AUC (Area Under the Curve) scores are a valuable tool for evaluating the performance of binary classification models, particularly when the class distribution is highly imbalanced. Unlike traditional AUC scores, partial AUC scores concentrate on a specific region of the ROC (Receiver Operating Characteristic) curve, offering a more detailed evaluation of the model's performance. This blog post will dive into what partial AUC scores are, how they are calculated, and why they are essential for evaluating imbalanced datasets. We will also include relevant examples and a code example using Python to help make these concepts clearer. This article was published as a part of the Data Science Blogathon.

This open access book provides a comprehensive overview of the state of the art in research and applications of Foundation Models and is intended for readers familiar with basic Natural Language Processing (NLP) concepts. Over the recent years, a revolutionary new paradigm has been developed for training models for NLP. These models are first pre-trained on large collections of text documents to acquire general syntactic knowledge and semantic information. Then, they are fine-tuned for specific tasks, which they can often solve with superhuman accuracy. When the models are large enough, they can be instructed by prompts to solve new tasks without any fine-tuning. Moreover, they can be applied to a wide range of different media and problem domains, ranging from image and video processing to robot control learning. Because they provide a blueprint for solving many tasks in artificial intelligence, they have been called Foundation Models. After a brief introduction to basic NLP models the main pre-trained language models BERT, GPT and sequence-to-sequence transformer are described, as well as the concepts of self-attention and context-sensitive embedding. Then, different approaches to improving these models are discussed, such as expanding the pre-training criteria, increasing the length of input texts, or including extra knowledge. An overview of the best-performing models for about twenty application areas is then presented, e.g., question answering, translation, story generation, dialog systems, generating images from text, etc. For each application area, the strengths and weaknesses of current models are discussed, and an outlook on further developments is given. In addition, links are provided to freely available program code. A concluding chapter summarizes the economic opportunities, mitigation of risks, and potential developments of AI.