In many real-world settings, the critical class is rare and a missed detection carries a disproportionately high cost. For example, tumors are rare and a false negative diagnosis could have severe consequences on treatment outcomes; fraudulent banking transactions are rare and an undetected occurrence could result in significant losses or legal penalties. In such contexts, systems are often operated at a high true positive rate, which may require tolerating high false positives. In this paper, we present a novel approach to address the challenge of minimizing false positives for systems that need to operate at a high true positive rate. We propose a ranking-based regularization (RankReg) approach that is easy to implement, and show empirically that it not only effectively reduces false positives, but also complements conventional imbalanced learning losses. With this novel technique in hand, we conduct a series of experiments on three broadly explored datasets (CIFAR-10&100 and Melanoma) and show that our approach lifts the previous state-of-the-art performance by notable margins.

Due to the increasing number of graduates, many applicants experience the situation about finding a job, and employers experience difficulty filtering job applicants, which might negatively impact their effectiveness. However, most job-hunting websites lack job recommendation and CV filtering or ranking functionality, which are not integrated into the system. Thus, a smart job hunter combined with the above functionality will be conducted in this project, which contains job recommendations, CV ranking and even a job dashboard for skills and job applicant functionality. Job recommendation and CV ranking starts from the automatic keyword extraction and end with the Job/CV ranking algorithm. Automatic keyword extraction is implemented by Job2Skill and the CV2Skill model based on Bert. Job2Skill consists of two components, text encoder and Gru-based layers, while CV2Skill is mainly based on Bert and fine-tunes the pre-trained model by the Resume- Entity dataset. Besides, to match skills from CV and job description and rank lists of jobs and candidates, job/CV ranking algorithms have been provided to compute the occurrence ratio of skill words based on TFIDF score and match ratio of the total skill numbers. Besides, some advanced features have been integrated into the website to improve user experiences, such as the calendar and sweetalert2 plugin. And some basic features to go through job application processes, such as job application tracking and interview arrangement.

Background: Alzheimer's disease (AD) is the most common type of age-related dementia, affecting 6.2 million people aged 65 or older according to CDC data. It is commonly agreed that discovering an effective AD diagnosis biomarker could have enormous public health benefits, potentially preventing or delaying up to 40% of dementia cases. Tau neurofibrillary tangles are the primary driver of downstream neurodegeneration and subsequent cognitive impairment in AD, resulting in structural deformations such as hippocampal atrophy that can be observed in magnetic resonance imaging (MRI) scans. Objective: To build a surface-based model to 1) detect differences between APOE subgroups in patterns of tau deposition and hippocampal atrophy, and 2) use the extracted surface-based features to predict cognitive decline. Methods: Using data obtained from different institutions, we develop a surface-based federated Chow test model to study the synergistic effects of APOE, a previously reported significant risk factor of AD, and tau on hippocampal surface morphometry. Results: We illustrate that the APOE-specific morphometry features correlate with AD progression and better predict future AD conversion than other MRI biomarkers. For example, a strong association between atrophy and abnormal tau was identified in hippocampal subregion cornu ammonis 1 (CA1 subfield) and subiculum in e4 homozygote cohort. Conclusion: Our model allows for identifying MRI biomarkers for AD and cognitive decline prediction and may uncover a corner of the neural mechanism of the influence of APOE and tau deposition on hippocampal morphology.

To advance automated detection of extreme weather events, which are increasing in frequency and intensity with climate change, we explore modifications to a novel light-weight Context Guided convolutional neural network architecture trained for semantic segmentation of tropical cyclones and atmospheric rivers in climate data. Our primary focus is on tropical cyclones, the most destructive weather events, for which current models show limited performance. We investigate feature engineering, data augmentation, learning rate modifications, alternative loss functions, and architectural changes. In contrast to previous approaches optimizing for intersection over union, we specifically seek to improve recall to penalize under-counting and prioritize identification of tropical cyclones. We report success through the use of weighted loss functions to counter class imbalance for these rare events. We conclude with directions for future research on extreme weather events detection, a crucial task for prediction, mitigation, and equitable adaptation to the impacts of climate change.

Endoscopic video recordings are widely used in minimally invasive robot-assisted surgery, but when the endoscope is outside the patient's body, it can capture irrelevant segments that may contain sensitive information. To address this, we propose a framework that accurately detects out-of-body frames in surgical videos by leveraging self-supervision with minimal data labels. We use a massive amount of unlabeled endoscopic images to learn meaningful representations in a self-supervised manner. Our approach, which involves pre-training on an auxiliary task and fine-tuning with limited supervision, outperforms previous methods for detecting out-of-body frames in surgical videos captured from da Vinci X and Xi surgical systems. The average F1 scores range from 96.00 to 98.02. Remarkably, using only 5% of the training labels, our approach still maintains an average F1 score performance above 97, outperforming fully-supervised methods with 95% fewer labels. These results demonstrate the potential of our framework to facilitate the safe handling of surgical video recordings and enhance data privacy protection in minimally invasive surgery.

The recent rise of machine learning (ML) has been leveraged by practitioners and researchers to provide new solutions to an ever growing number of business problems. As with other ML applications, these solutions rely on model selection, which is typically achieved by evaluating certain metrics on models separately and selecting the model whose evaluations (i.e., accuracy-related loss and/or certain interpretability measures) are optimal. However, empirical evidence suggests that, in practice, multiple models often attain competitive results. Therefore, while models' overall performance could be similar, they could operate quite differently. This results in an implicit tradeoff in models' performance throughout the feature space which resolving requires new model selection tools. This paper explores methods for comparing predictive models in an interpretable manner to uncover the tradeoff and help resolve it. To this end, we propose various methods that synthesize ideas from supervised learning, unsupervised learning, dimensionality reduction, and visualization to demonstrate how they can be used to inform model developers about the model selection process. Using various datasets and a simple Python interface, we demonstrate how practitioners and researchers could benefit from applying these approaches to better understand the broader impact of their model selection choices.

Multiplexed detection of biomarkers in real-time is crucial for sensitive and accurate diagnosis at the point of use. This scenario poses tremendous challenges for detection and identification of signals of varying shape and quality at the edge of the signal-to-noise limit. Here, we demonstrate a robust target identification scheme that utilizes a Deep Neural Network (DNN) for multiplex detection of single particles and molecular biomarkers. The model combines fast wavelet particle detection with Short-Time Fourier Transform analysis, followed by DNN identification on an AI-specific edge device (Google Coral Dev board). The approach is validated using multi-spot optical excitation of Klebsiella Pneumoniae bacterial nucleic acids flowing through an optofluidic waveguide chip that produces fluorescence signals of varying amplitude, duration, and quality. Amplification-free 3× multiplexing in real-time is demonstrated with excellent specificity, sensitivity, and a classification accuracy of 99.8%. These results show that a minimalistic DNN design optimized for mobile devices provides a robust framework for accurate pathogen detection using compact, low-cost diagnostic devices.

Disentangling complex data to its latent factors of variation is a fundamental task in representation learning. Existing work on sequential disentanglement mostly provides two factor representations, i.e., it separates the data to time-varying and time-invariant factors. In contrast, we consider multifactor disentanglement in which multiple (more than two) semantic disentangled components are generated. Key to our approach is a strong inductive bias where we assume that the underlying dynamics can be represented linearly in the latent space. Under this assumption, it becomes natural to exploit the recently introduced Koopman autoencoder models. However, disentangled representations are not guaranteed in Koopman approaches, and thus we propose a novel spectral loss term which leads to structured Koopman matrices and disentanglement. Overall, we propose a simple and easy to code new deep model that is fully unsupervised and it supports multifactor disentanglement. We showcase new disentangling abilities such as swapping of individual static factors between characters, and an incremental swap of disentangled factors from the source to the target. Moreover, we evaluate our method extensively on two factor standard benchmark tasks where we significantly improve over competing unsupervised approaches, and we perform competitively in comparison to weakly- and self-supervised state-of-the-art approaches. The code is available at https://github.com/azencot-group/SKD.

Conformance checking techniques allow us to evaluate how well some exhibited behaviour, represented by a trace of monitored events, conforms to a specified process model. Modern monitoring and activity recognition technologies, such as those relying on sensors, the IoT, statistics and AI, can produce a wealth of relevant event data. However, this data is typically characterised by noise and uncertainty, in contrast to the assumption of a deterministic event log required by conformance checking algorithms. In this paper, we extend alignment-based conformance checking to function under a probabilistic event log. We introduce a weighted trace model and weighted alignment cost function, and a custom threshold parameter that controls the level of confidence on the event data vs. the process model. The resulting algorithm considers activities of lower but sufficiently high probability that better align with the process model. We explain the algorithm and its motivation both from formal and intuitive perspectives, and demonstrate its functionality in comparison with deterministic alignment using real-life datasets.

The current state of the art systems in Artificial Intelligence (AI) enabled intrusion detection use a variety of black box methods. These black box methods are generally trained using Error Based Learning (EBL) techniques with a focus on creating accurate models. These models have high performative costs and are not easily explainable. A white box Competitive Learning (CL) based eXplainable Intrusion Detection System (X-IDS) offers a potential solution to these problem. CL models utilize an entirely different learning paradigm than EBL approaches. This different learning process makes the CL family of algorithms innately explainable and less resource intensive. In this paper, we create an X-IDS architecture that is based on DARPA's recommendation for explainable systems. In our architecture we leverage CL algorithms like, Self Organizing Maps (SOM), Growing Self Organizing Maps (GSOM), and Growing Hierarchical Self Organizing Map (GHSOM). The resulting models can be data-mined to create statistical and visual explanations. Our architecture is tested using NSL-KDD and CIC-IDS-2017 benchmark datasets, and produces accuracies that are 1% - 3% less than EBL models. However, CL models are much more explainable than EBL models. Additionally, we use a pruning process that is able to significantly reduce the size of these CL based models. By pruning our models, we are able to increase prediction speeds. Lastly, we analyze the statistical and visual explanations generated by our architecture, and we give a strategy that users could use to help navigate the set of explanations. These explanations will help users build trust with an Intrusion Detection System (IDS), and allow users to discover ways to increase the IDS's potency.