Data drift is the change in model input data that is one of the key factors leading to machine learning models performance degradation over time. Monitoring drift helps detecting these issues and preventing their harmful consequences. Meaningful drift interpretation is a fundamental step towards effective re-training of the model. In this study we propose an end-to-end framework for reliable model-agnostic change-point detection and interpretation in large task-oriented dialog systems, proven effective in multiple customer deployments. We evaluate our approach and demonstrate its benefits with a novel variant of intent classification training dataset, simulating customer requests to a dialog system. We make the data publicly available.

Differential privacy (DP), introduced in [21], has gained widespread adoption by governments, companies, and researchers by formally ensuring plausible deniability for participating individuals. This is achieved by guaranteeing that a curious observer of the output of a query cannot be confident in their answer to the following binary hypothesis test: did a particular individual participate in the dataset or not? For example, introducing sufficient randomness when training a model on a certain dataset ensures a desired level of differential privacy. This in turn ensures that an individual's sensitive information cannot be inferred from the trained model with high confidence. However, calibrating the right amount of noise can be a challenging process. It is easy to make mistakes when implementing a DP mechanism as it can involve intricacies like micro-batching, sensitivity analysis, and privacy accounting. Even with a correct implementation, there are several known incidents of published DP algorithms with miscalculated privacy guarantees that falsely report higher levels of privacy [16, 33, 39, 46, 56, 57]. Data-driven approaches to auditing a mechanism for a violation of a claimed privacy guarantee can significantly mitigate the danger of unintentionally leaking sensitive data.

**Background:** Accurate 3D CT scan segmentation of gastric tumors is pivotal for diagnosis and treatment. The challenges lie in the irregular shapes, blurred boundaries of tumors, and the inefficiency of existing methods. **Purpose:** We conducted a study to introduce a model, utilizing human-guided knowledge and unique modules, to address the challenges of 3D tumor segmentation. **Methods:** We developed the PropNet framework, propagating radiologists' knowledge from 2D annotations to the entire 3D space. This model consists of a proposing stage for coarse segmentation and a refining stage for improved segmentation, using two-way branches for enhanced performance and an up-down strategy for efficiency. **Results:** With 98 patient scans for training and 30 for validation, our method achieves a significant agreement with manual annotation (Dice of 0.803) and improves efficiency. The performance is comparable in different scenarios and with various radiologists' annotations (Dice between 0.785 and 0.803). Moreover, the model shows improved prognostic prediction performance (C-index of 0.620 vs. 0.576) on an independent validation set of 42 patients with advanced gastric cancer. **Conclusions:** Our model generates accurate tumor segmentation efficiently and stably, improving prognostic performance and reducing high-throughput image reading workload. This model can accelerate the quantitative analysis of gastric tumors and enhance downstream task performance.

Large-scale pre-trained language models (PLMs) have shown great potential in natural language processing tasks. Leveraging the capabilities of PLMs to enhance automatic speech recognition (ASR) systems has also emerged as a promising research direction. However, previous works may be limited by the inflexible structures of PLMs and the insufficient utilization of PLMs. To alleviate these problems, we propose the hierarchical knowledge distillation (HKD) on the continuous integrate-and-fire (CIF) based ASR models. To transfer knowledge from PLMs to the ASR models, HKD employs cross-modal knowledge distillation with contrastive loss at the acoustic level and knowledge distillation with regression loss at the linguistic level. Compared with the original CIF-based model, our method achieves 15% and 9% relative error rate reduction on the AISHELL-1 and LibriSpeech datasets, respectively.

This paper studies the online node classification problem under a transductive learning setting. Current methods either invert a graph kernel matrix with $\mathcal{O}(n^3)$ runtime and $\mathcal{O}(n^2)$ space complexity or sample a large volume of random spanning trees, thus are difficult to scale to large graphs. In this work, we propose an improvement based on the \textit{online relaxation} technique introduced by a series of works (Rakhlin et al.,2012; Rakhlin and Sridharan, 2015; 2017). We first prove an effective regret $\mathcal{O}(\sqrt{n^{1+\gamma}})$ when suitable parameterized graph kernels are chosen, then propose an approximate algorithm FastONL enjoying $\mathcal{O}(k\sqrt{n^{1+\gamma}})$ regret based on this relaxation. The key of FastONL is a \textit{generalized local push} method that effectively approximates inverse matrix columns and applies to a series of popular kernels. Furthermore, the per-prediction cost is $\mathcal{O}(\text{vol}({\mathcal{S}})\log 1/\epsilon)$ locally dependent on the graph with linear memory cost. Experiments show that our scalable method enjoys a better tradeoff between local and global consistency.

Spoof localization, also called segment-level detection, is a crucial task that aims to locate spoofs in partially spoofed audio. The equal error rate (EER) is widely used to measure performance for such biometric scenarios. Although EER is the only threshold-free metric, it is usually calculated in a point-based way that uses scores and references with a pre-defined temporal resolution and counts the number of misclassified segments. Such point-based measurement overly relies on this resolution and may not accurately measure misclassified ranges. To properly measure misclassified ranges and better evaluate spoof localization performance, we upgrade point-based EER to range-based EER. Then, we adapt the binary search algorithm for calculating range-based EER and compare it with the classical point-based EER. Our analyses suggest utilizing either range-based EER, or point-based EER with a proper temporal resolution can fairly and properly evaluate the performance of spoof localization.

A heart murmur is an atypical sound produced by the flow of blood through the heart. It can be a sign of a serious heart condition, so detecting heart murmurs is critical for identifying and managing cardiovascular diseases. However, current methods for identifying murmurous heart sounds do not fully utilize the valuable insights that can be gained by exploring intrinsic properties of heart sound signals. To address this issue, this study proposes a new discriminatory set of multiscale features based on the self-similarity and complexity properties of heart sounds, as derived in the wavelet domain. Self-similarity is characterized by assessing fractal behaviors, while complexity is explored by calculating wavelet entropy. We evaluated the diagnostic performance of these proposed features for detecting murmurs using a set of standard classifiers. When applied to a publicly available heart sound dataset, our proposed wavelet-based multiscale features achieved comparable performance to existing methods with fewer features. This suggests that self-similarity and complexity properties in heart sounds could be potential biomarkers for improving the accuracy of murmur detection.

Many event sequence data exhibit mutually exciting or inhibiting patterns. Reliable detection of such temporal dependency is crucial for scientific investigation. The de facto model is the Multivariate Hawkes Process (MHP), whose impact function naturally encodes a causal structure in Granger causality. However, the vast majority of existing methods use direct or nonlinear transform of standard MHP intensity with constant baseline, inconsistent with real-world data. Under irregular and unknown heterogeneous intensity, capturing temporal dependency is hard as one struggles to distinguish the effect of mutual interaction from that of intensity fluctuation. In this paper, we address the short-term temporal dependency detection issue. We show the maximum likelihood estimation (MLE) for cross-impact from MHP has an error that can not be eliminated but may be reduced by order of magnitude, using heterogeneous intensity not of the target HP but of the interacting HP. Then we proposed a robust and computationally-efficient method modified from MLE that does not rely on the prior estimation of the heterogeneous intensity and is thus applicable in a data-limited regime (e.g., few-shot, no repeated observations). Extensive experiments on various datasets show that our method outperforms existing ones by notable margins, with highlighted novel applications in neuroscience.

In photo editing, it is common practice to remove visual distractions to improve the overall image quality and highlight the primary subject. However, manually selecting and removing these small and dense distracting regions can be a laborious and time-consuming task. In this paper, we propose an interactive distractor selection method that is optimized to achieve the task with just a single click. Our method surpasses the precision and recall achieved by the traditional method of running panoptic segmentation and then selecting the segments containing the clicks. We also showcase how a transformer-based module can be used to identify more distracting regions similar to the user's click position. Our experiments demonstrate that the model can effectively and accurately segment unknown distracting objects interactively and in groups. By significantly simplifying the photo cleaning and retouching process, our proposed model provides inspiration for exploring rare object segmentation and group selection with a single click.

Causal mapping of the functional organisation of the human brain requires evidence of \textit{necessity} available at adequate scale only from pathological lesions of natural origin. This demands inferential models with sufficient flexibility to capture both the observable distribution of pathological damage and the unobserved distribution of the neural substrate. Current model frameworks -- both mass-univariate and multivariate -- either ignore distributed lesion-deficit relations or do not model them explicitly, relying on featurization incidental to a predictive task. Here we initiate the application of deep generative neural network architectures to the task of lesion-deficit inference, formulating it as the estimation of an expressive hierarchical model of the joint lesion and deficit distributions conditioned on a latent neural substrate. We implement such deep lesion deficit inference with variational convolutional volumetric auto-encoders. We introduce a comprehensive framework for lesion-deficit model comparison, incorporating diverse candidate substrates, forms of substrate interactions, sample sizes, noise corruption, and population heterogeneity. Drawing on 5500 volume images of ischaemic stroke, we show that our model outperforms established methods by a substantial margin across all simulation scenarios, including comparatively small-scale and noisy data regimes. Our analysis justifies the widespread adoption of this approach, for which we provide an open source implementation: https://github.com/guilherme-pombo/vae_lesion_deficit