Auscultation is a key method for early diagnosis of respiratory and pulmonary diseases, relying on skilled healthcare professionals. However, the process is often subjective, with variability between experts. As a result, numerous deep learning-based automatic classification methods have emerged, most of which focus on respiratory sound classification. In contrast, research on respiratory sound event detection remains limited. Existing sound event detection methods typically rely on frame-level predictions followed by post-processing to generate event-level outputs, making interval boundaries challenging to learn directly. Furthermore, many approaches can only handle fixed-length audio, limiting their applicability to variable-length respiratory sounds. Additionally, the impact of respiratory sound location information on detection performance has not been extensively explored. To address these issues, we propose a graph neural network-based framework with anchor intervals, capable of handling variable-length audio and providing more precise temporal localization for abnormal respiratory sound events. Our method improves both the flexibility and applicability of respiratory sound detection. Experiments on the SPRSound 2024 and HF Lung V1 datasets demonstrate the effectiveness of the proposed approach, and incorporating respiratory position information enhances the discrimination between abnormal sounds. The reference implementation is available at https://github.com/chumingqian/EzhouNet.

AI text-to-app tools promise high quality applications and websites in minutes, yet no public benchmark rigorously verifies those claims. We introduce UI-Bench, the first large-scale benchmark that evaluates visual excellence across competing AI text-to-app tools through expert pairwise comparison. Spanning 10 tools, 30 prompts, 300 generated sites, and 4,000+ expert judgments, UI-Bench ranks systems with a TrueSkill-derived model that yields calibrated confidence intervals. UI-Bench establishes a reproducible standard for advancing AI-driven web design. We release (i) the complete prompt set, (ii) an open-source evaluation framework, and (iii) a public leaderboard. The generated sites rated by participants will be released soon. View the UI-Bench leaderboard at https://uibench.ai/leaderboard.

Despite advances in improving large language model (LLM) to refuse to answer malicious instructions, widely used LLMs remain vulnerable to jailbreak attacks where attackers generate instructions with distributions differing from safety alignment corpora. New attacks expose LLMs' inability to recognize unseen malicious instructions, highlighting a critical distributional mismatch between training data and real-world attacks that forces developers into reactive patching cycles. To tackle this challenge, we propose IMAGINE, a synthesis framework that leverages embedding space distribution analysis to generate jailbreak-like instructions. This approach effectively fills the distributional gap between authentic jailbreak patterns and safety alignment corpora. IMAGINE follows an iterative optimization process that dynamically evolves text generation distributions across iterations, thereby augmenting the coverage of safety alignment data distributions through synthesized data examples. Based on the safety-aligned corpus enhanced through IMAGINE, our framework demonstrates significant decreases in attack success rate on Qwen2.5, Llama3.1, and Llama3.2 without compromising their utility.

Efforts to understand the universe could get a boost from an AI developed by Google DeepMind. The algorithm, which can reduce unwanted noise by up to 100 times, could allow the Laser Interferometer Gravitational-Wave Observatory (LIGO) to spot a particular type of black hole that has so far eluded us. LIGO is designed to detect the gravitational waves produced when objects such as black holes spiral into each other and collide. These waves cross the universe at the speed of light, but the fluctuations they cause in space-time are extremely small – 10,000 times smaller than the nucleus of an atom. Since its first observations 10 years ago, LIGO has recorded such signals produced by nearly 100 black hole collisions.

When Synthesia launched in 2017, its primary purpose was to match AI versions of real human faces--for example, the former footballer David Beckham--with dubbed voices speaking in different languages. A few years later, in 2020, it started giving the companies that signed up for its services the opportunity to make professional-level presentation videos starring either AI versions of staff members or consenting actors. The avatars' body movements could be jerky and unnatural, their accents sometimes slipped, and the emotions indicated by their voices didn't always match their facial expressions. Now Synthesia's avatars have been updated with more natural mannerisms and movements, as well as expressive voices that better preserve the speaker's accent--making them appear more humanlike than ever before. For Synthesia's corporate clients, these avatars will make for slicker presenters of financial results, internal communications, or staff training videos.

Resonac, a Japanese chip-materials maker, has announced the creation of Joint 3, which it describes as a consortium of 27 companies working together on semiconductor-related developments. "With next-generation technologies like generative AI and self-driving cars rapidly spreading, the technology required for semiconductors is getting more advanced and complex," Resonac CEO Hidehito Takahashi said Wednesday. Companies from a number of countries will be involved in Joint 3, which is led by Resonac. The list includes St Paul, Minnesota's 3M, Rolla, Missouri's Brewer Science, Sunnyvale, California's Synopsys and Singapore-headquartered, Hong Kong-listed ASMPT.

Parametric partial differential equations (PDEs) are fundamental mathematical tools for modeling complex physical systems, yet their numerical evaluation across parameter spaces remains computationally intensive when using conventional high-fidelity solvers. To address this challenge, we propose a novel physical law-corrected prior Gaussian process (LC-prior GP) surrogate modeling framework that effectively integrates data-driven learning with underlying physical constraints to flexibly handle multi-coupled variables defined on complex geometries. The proposed approach leverages proper orthogonal decomposition (POD) to parameterize high-dimensional PDE solutions via their dominant modes and associated coefficients, thereby enabling efficient Gaussian process (GP) surrogate modeling within a reduced-dimensional coefficient space. A key contribution lies in the incorporation of physical laws together with a limited number of parameter samples to correct the GP posterior mean, thus avoiding reliance on computationally expensive numerical solvers. Furthermore, interpolation functions are constructed to describe the mapping from the full parameter space to the physics-based correction term. This mapping is subsequently backpropagated to constrain the original GP surrogate, yielding a more physically consistent conditional prior. To handle irregular geometries, the radial basis function-finite difference (RBF-FD) method is incorporated during training set computation, with its inherent differentiation matrices providing both computational efficiency and numerical accuracy for physical constraint optimization. The effectiveness of the proposed method is demonstrated through numerical experiments involving a reaction-diffusion model, miscible flooding models, and Navier-Stokes equations with multi-physics coupling defined on irregular domains.

Accurate conditional prediction in the regression setting plays an important role in many real-world problems. Typically, a point prediction often falls short since no attempt is made to quantify the prediction accuracy. Classically, under the normality and linearity assumptions, the Prediction Interval (PI) for the response variable can be determined routinely based on the $t$ distribution. Unfortunately, these two assumptions are rarely met in practice. To fully avoid these two conditions, we develop a so-called calibration PI (cPI) which leverages estimations by Deep Neural Networks (DNN) or kernel methods. Moreover, the cPI can be easily adjusted to capture the estimation variability within the prediction procedure, which is a crucial error source often ignored in practice. Under regular assumptions, we verify that our cPI has an asymptotically valid coverage rate. We also demonstrate that cPI based on the kernel method ensures a coverage rate with a high probability when the sample size is large. Besides, with several conditions, the cPI based on DNN works even with finite samples. A comprehensive simulation study supports the usefulness of cPI, and the convincing performance of cPI with a short sample is confirmed with two empirical datasets.

While Sharpness-Aware Minimization (SAM) improves generalization in deep neural networks by minimizing both loss and sharpness, it suffers from inefficiency in distributed large-batch training. We present Landscape-Smoothed SAM (LSAM), a novel optimizer that preserves SAM's generalization advantages while offering superior efficiency. LSAM integrates SAM's adversarial steps with an asynchronous distributed sampling strategy, generating an asynchronous distributed sampling scheme, producing a smoothed sharpness-aware loss landscape for optimization. This design eliminates synchronization bottlenecks, accelerates large-batch convergence, and delivers higher final accuracy compared to data-parallel SAM.

Agentic workflows commonly coordinate multiple models and tools with complex control logic. They are quickly becoming the dominant paradigm for AI applications. However, serving them remains inefficient with today's frameworks. The key problem is that they expose workflows as opaque sequences of model and tool calls that tightly couple agent logic with model and hardware choices. Often, these workflow components are fragmented across different entities, preventing systems from reasoning about trade-offs across accuracy, latency, energy, and cost. This leads to resource waste and degraded service-level objectives (SLOs). We present Murakkab, a resource-efficient serving system for agentic workflows. Murakkab introduces a declarative abstraction that decouples workflow specification from execution configuration. A profile-guided optimizer and adaptive runtime jointly manage the full stack: orchestrating workflow components, mapping them to models and hardware, and dynamically reconfiguring execution to satisfy user-defined SLOs. By exposing the internal structure of agentic workflows, Murakkab enables cross-layer optimization that existing frameworks and cloud schedulers cannot achieve. Our evaluation on diverse workflows shows that Murakkab reduces GPU usage by up to 2.8$\times$, energy consumption by 3.7$\times$, and cost by 4.3$\times$ while maintaining SLOs.