The rapid evolution of Artificial Intelligence (AI) and Large Language Models (LLMs) has opened up new opportunities in the area of cybersecurity, especially in the exploitation automation landscape and penetration testing. This study explores Android penetration testing automation using LLM-based tools, especially PentestGPT, to identify and execute rooting techniques. Through a comparison of the traditional manual rooting process and exploitation methods produced using AI, this study evaluates the efficacy, reliability, and scalability of automated penetration testing in achieving high-level privilege access on Android devices. With the use of an Android emulator (Genymotion) as the testbed, we fully execute both traditional and exploit-based rooting methods, automating the process using AI-generated scripts. Secondly, we create a web application by integrating OpenAI's API to facilitate automated script generation from LLM-processed responses. The research focuses on the effectiveness of AI-enabled exploitation by comparing automated and manual penetration testing protocols, by determining LLM weaknesses and strengths along the way. We also provide security suggestions of AI-enabled exploitation, including ethical factors and potential misuse. The findings exhibit that while LLMs can significantly streamline the workflow of exploitation, they need to be controlled by humans to ensure accuracy and ethical application. This study adds to the increasing body of literature on AI-powered cybersecurity and its effect on ethical hacking, security research, and mobile device security.

Uncertainty estimation is essential for enhancing the reliability of Large Language Models (LLMs), particularly in high-stakes applications. Existing methods often overlook semantic dependencies, relying on token-level probability measures that fail to capture structural relationships within the generated text. We propose GENUINE: Graph ENhanced mUlti-level uncertaINty Estimation for Large Language Models, a structure-aware framework that leverages dependency parse trees and hierarchical graph pooling to refine uncertainty quantification. By incorporating supervised learning, GENUINE effectively models semantic and structural relationships, improving confidence assessments. Extensive experiments across NLP tasks show that GENUINE achieves up to 29% higher AUROC than semantic entropy-based approaches and reduces calibration errors by over 15%, demonstrating the effectiveness of graph-based uncertainty modeling. The code is available at https://github.com/ODYSSEYWT/GUQ.

Oral diseases remain one of the most pervasive global health issues, affecting over 3.5 billion individuals, which accounts for over 43% of the global population as reported by the World Health Organization [1]. This widespread prevalence underscores the critical importance of dentistry, not only for clinical needs but also for enhancing the overall quality of life for a large portion of the global population. In modern dental practice, digital dentistry plays a crucial role in streamlining workflows and enhancing patient outcomes. Cone-Beam Computed Tomography (CBCT) visualizes 3D anatomical structures, including tooth morphology, alveolar bone, and surrounding tissues [2], while intraoral scans (IOS) provide high-resolution images of occlusal surfaces that are crucial for treatment planning and prosthesis design [3]. However, these imaging modalities still require extensive manual and time-consuming analysis to identify and plan treatments [4]. Consequently, numerous research efforts now focus on automating key tasks such as caries detection [5-7], orthodontic treatment planning [8-10], and designing dental prostheses, including implants, crowns, and bridges [11-13].

Large Language Models (LLMs) are large-scale pretrained models that have achieved remarkable success across diverse domains. These successes have been driven by unprecedented complexity and scale in both data and computations. However, due to the high costs of training such models, brute-force trial-and-error approaches to improve LLMs are not feasible. Inspired by the success of inverse problems in uncovering fundamental scientific laws, this position paper advocates that inverse problems can also efficiently uncover scaling laws that guide the building of LLMs to achieve the desirable performance with significantly better cost-effectiveness.

This paper presents our team's solution to Shared Task 7 of NLPCC-2025, which focuses on sentence-level gender bias detection and mitigation in Chinese. The task aims to promote fairness and con-trollability in natural language generation by automatically detecting, classifying, and mitigating gender bias. To address this challenge, we adopt a fine-tuning approach based on large language models (LLMs), efficiently adapt to the bias detection task via Low-Rank Adaptation (LoRA). In terms of data processing, we construct a more balanced training set to alleviate class imbalance and introduce heterogeneous samples from multiple sources to enhance model generalization. For the detection and classification sub-tasks, we employ a majority voting strategy that integrates outputs from multiple expert models to boost performance. Additionally, to improve bias generation detection and mitigation, we design a multi-temperature sampling mechanism to capture potential variations in bias expression styles. Experimental results demonstrate the effectiveness of our approach in bias detection, classification, and mitigation. Our method ultimately achieves an average score of 47.90%, ranking fourth in the shared task.

Graph Neural Networks (GNNs) have gained traction in the complex domain of drug discovery because of their ability to process graph-structured data such as drug molecule models. This approach has resulted in a myriad of methods and models in published literature across several categories of drug discovery research. This paper covers the research categories comprehensively with recent papers, namely molecular property prediction, including drug-target binding affinity prediction, drug-drug interaction study, microbiome interaction prediction, drug repositioning, retrosynthesis, and new drug design, and provides guidance for future work on GNNs for drug discovery.

Active Membership Inference T est (aMINT) is a method designed to detect whether given data were used during the training of machine learning models. In Active MINT, we propose a novel multitask learning process that involves training simultaneously two models: the original or Audited Model, and a secondary model, referred to as the MINT Model, responsible for identifying the data used for training the Audited Model. This novel multi-task learning approach has been designed to incorporate the auditability of the model as an optimization objective during the training process of neural networks. The proposed approach incorporates intermediate activation maps as inputs to the MINT layers, which are trained to enhance the detection of training data. W e present results using a wide range of neural networks, from lighter architectures such as MobileNet to more complex ones such as Vision Transformers, evaluated in 5 public benchmarks. Our proposed Active MINT achieves over 80% accuracy in detecting if given data was used for training, significantly outperforming previous approaches in the literature.

Constraint Programming and its high-level modeling languages have long been recognized for their potential to achieve the holy grail of problem-solving. However, the complexity of modeling languages, the large number of global constraints, and the art of creating good models have often hindered non-experts from choosing CP to solve their combinatorial problems. While generating an expert-level model from a natural-language description of a problem would be the dream, we are not yet there. We propose a tutoring system called CP-Model-Zoo, exploiting expert-written models accumulated through the years. CP-Model-Zoo retrieves the closest source code model from a database based on a user's natural language description of a combinatorial problem. It ensures that expert-validated models are presented to the user while eliminating the need for human data labeling. Our experiments show excellent accuracy in retrieving the correct model based on a user-input description of a problem simulated with different levels of expertise.

Personalizing combination therapies in oncology requires navigating an immense space of possible drug and dose combinations, a task that remains largely infeasible through exhaustive experimentation. Recent developments in patient-derived models have enabled high-throughput ex vivo screening, but the number of feasible experiments is limited. Further, a tight therapeutic window makes gathering molecular profiling information (e.g. RNA-seq) impractical as a means of guiding drug response prediction. This leads to a challenging cold-start problem: how do we select the most informative combinations to test early, when no prior information about the patient is available? We propose a strategy that leverages a pretrained deep learning model built on historical drug response data. The model provides both embeddings for drug combinations and dose-level importance scores, enabling a principled selection of initial experiments. We combine clustering of drug embeddings to ensure functional diversity with a dose-weighting mechanism that prioritizes doses based on their historical informativeness. Retrospective simulations on large-scale drug combination datasets show that our method substantially improves initial screening efficiency compared to baselines, offering a viable path for more effective early-phase decision-making in personalized combination drug screens.

Large language models like ChatGPT are increasingly used in classrooms, but they often provide outdated or fabricated information that can mislead students. Retrieval Augmented Generation (RAG) improves reliability of LLMs by grounding responses in external resources. We investigate two accessible RAG paradigms, vector-based retrieval and graph-based retrieval to identify best practices for classroom question answering (QA). Existing comparative studies fail to account for pedagogical factors such as educational disciplines, question types, and practical deployment costs. Using a novel dataset, EduScopeQA, of 3,176 questions across academic subjects, we measure performance on various educational query types, from specific facts to broad thematic discussions. We also evaluate system alignment with a dataset of systematically altered textbooks that contradict the LLM's latent knowledge. We find that OpenAI Vector Search RAG (representing vector-based RAG) performs well as a low-cost generalist, especially for quick fact retrieval. On the other hand, GraphRAG Global excels at providing pedagogically rich answers to thematic queries, and GraphRAG Local achieves the highest accuracy with the dense, altered textbooks when corpus integrity is critical. Accounting for the 10-20x higher resource usage of GraphRAG (representing graph-based RAG), we show that a dynamic branching framework that routes queries to the optimal retrieval method boosts fidelity and efficiency. These insights provide actionable guidelines for educators and system designers to integrate RAG-augmented LLMs into learning environments effectively.