With the rapid development of online medical platforms, consumer health questions (CHQs) are inefficient in diagnosis due to redundant information and frequent non-professional terms. The medical question summary (MQS) task aims to transform CHQs into streamlined doctors' frequently asked questions (FAQs), but existing methods still face challenges such as poor identification of question focus and model hallucination. This paper explores the potential of large language models (LLMs) in the MQS task and finds that direct fine-tuning is prone to focus identification bias and generates unfaithful content. To this end, we propose an optimization framework based on core focus guidance. First, a prompt template is designed to drive the LLMs to extract the core focus from the CHQs that is faithful to the original text. Then, a fine-tuning dataset is constructed in combination with the original CHQ-FAQ pairs to improve the ability to identify the focus of the question. Finally, a multi-dimensional quality evaluation and selection mechanism is proposed to comprehensively improve the quality of the summary from multiple dimensions. We conduct comprehensive experiments on two widely-adopted MQS datasets using three established evaluation metrics. The proposed framework achieves state-of-the-art performance across all measures, demonstrating a significant boost in the model's ability to identify critical focus of questions and a notable mitigation of hallucinations. The source codes are freely available at https://github.com/DUT-LiuChao/FocusMed.

Reversible Instance Normalization (RevIN) is a key technique enabling simple linear models to achieve state-of-the-art performance in time series forecasting. While replacing its non-robust statistics with robust counterparts (termed R$^2$-IN) seems like a straightforward improvement, our findings reveal a far more complex reality. This paper deconstructs the perplexing performance of various normalization strategies by identifying four underlying theoretical contradictions. Our experiments provide two crucial findings: first, the standard RevIN catastrophically fails on datasets with extreme outliers, where its MSE surges by a staggering 683\%. Second, while the simple R$^2$-IN prevents this failure and unexpectedly emerges as the best overall performer, our adaptive model (A-IN), designed to test a diagnostics-driven heuristic, unexpectedly suffers a complete and systemic failure. This surprising outcome uncovers a critical, overlooked pitfall in time series analysis: the instability introduced by a simple or counter-intuitive heuristic can be more damaging than the statistical issues it aims to solve. The core contribution of this work is thus a new, cautionary paradigm for time series normalization: a shift from a blind search for complexity to a diagnostics-driven analysis that reveals not only the surprising power of simple baselines but also the perilous nature of naive adaptation.

Flow matching models generate high-fidelity molecular geometries but incur significant computational costs during inference, requiring hundreds of network evaluations. This inference overhead becomes the primary bottleneck when such models are employed in practice to sample large numbers of molecular candidates. This work discusses a training-free caching strategy that accelerates molecular geometry generation by predicting intermediate hidden states across solver steps. The proposed method operates directly on the SE(3)-equivariant backbone, is compatible with pretrained models, and is orthogonal to existing training-based accelerations and system-level optimizations. Experiments on the GEOM-Drugs dataset demonstrate that caching achieves a twofold reduction in wall-clock inference time at matched sample quality and a speedup of up to 3x compared to the base model with minimal sample quality degradation. Because these gains compound with other optimizations, applying caching alongside other general, lossless optimizations yield as much as a 7x speedup.

In this paper, our objective is to develop a multi-agent financial system that incorporates simulated trading, a technique extensively utilized by financial professionals. While current LLM-based agent models demonstrate competitive performance, they still exhibit significant deviations from real-world fund companies. A critical distinction lies in the agents' reliance on ``post-reflection'', particularly in response to adverse outcomes, but lack a distinctly human capability: long-term prediction of future trends. Therefore, we introduce QuantAgents, a multi-agent system integrating simulated trading, to comprehensively evaluate various investment strategies and market scenarios without assuming actual risks. Specifically, QuantAgents comprises four agents: a simulated trading analyst, a risk control analyst, a market news analyst, and a manager, who collaborate through several meetings. Moreover, our system incentivizes agents to receive feedback on two fronts: performance in real-world markets and predictive accuracy in simulated trading. Extensive experiments demonstrate that our framework excels across all metrics, yielding an overall return of nearly 300% over the three years (https://quantagents.github.io/).

Abstract--Detecting manipulated media has now become a pressing issue with the recent rise of deepfakes. Most existing approaches fail to generalize across diverse datasets and generation techniques. We thus propose a novel ensemble framework, combining the strengths of transformer-based architectures, such as Swin Transformers and ViTs, and texture-based methods, to achieve better detection accuracy and robustness. Our method introduces innovative data-splitting, sequential training, frequency splitting, patch-based attention, and face segmentation techniques to handle dataset imbalances, enhance high-impact regions (e.g., eyes and mouth), and improve generalization. Our model achieves state-of-the-art performance when tested on the DFWild-Cup dataset, a diverse subset of eight deepfake datasets. This work demonstrates that hybrid models can effectively address the evolving challenges of deepfake detection, offering a robust solution for real-world applications. The rapid advancement of deep learning and generative models has led to the proliferation of deepfakes. AI-generated images, videos, and audio recordings are becoming increasingly realistic, making it difficult for humans and traditional systems to distinguish between real and manipulated content.

The deployment of Large Language Models (LLMs) for structuring clinical data is critically hindered by their tendency to hallucinate facts and their inability to follow domain-specific rules. To address this, we introduce MedPAO, a novel agentic framework that ensures accuracy and verifiable reasoning by grounding its operation in established clinical protocols such as the ABCDEF protocol for CXR analysis. MedPAO decomposes the report structuring task into a transparent process managed by a Plan-Act-Observe (PAO) loop and specialized tools. This protocol-driven method provides a verifiable alternative to opaque, monolithic models. The efficacy of our approach is demonstrated through rigorous evaluation: MedPAO achieves an F1-score of 0.96 on the critical sub-task of concept categorization. Notably, expert radiologists and clinicians rated the final structured outputs with an average score of 4.52 out of 5, indicating a level of reliability that surpasses baseline approaches relying solely on LLM-based foundation models. The code is available at: https://github.com/MiRL-IITM/medpao-agent

Abstract--This paper outlines the design vision and planned evolution of Blexer v3, a modular and AI-driven rehabilitation ecosystem based on serious games. Building on insights from previous versions of the system, we propose a new architecture that aims to integrate multimodal sensing, real-time reasoning, and intelligent control. The envisioned system will include distinct modules for data collection, user state inference, and gameplay adaptation. Key features such as dynamic difficulty adjustment (DDA) and procedural content generation (PCG) are also considered to support personalized interventions. We present the complete conceptual framework of Blexer v3, which defines the modular structure and data flow of the system. This serves as the foundation for the next phase: the development of a functional prototype and its integration into clinical rehabilitation scenarios. Video games have evolved significantly since their inception in the 1960s, becoming a cultural force in the late 1980s and early 1990s [1]. With the growth of the videogame industry, games have expanded into fields such as education, military, and healthcare, known as Serious Games (SGs) [2]. In healthcare, SGs have shown promise in screening [3] and rehabilitation [4].

Radiology report evaluation is a crucial part of radiologists' training and plays a key role in ensuring diagnostic accuracy. As part of the standard reporting workflow, a junior radiologist typically prepares a preliminary report, which is then reviewed and edited by a senior radiologist to produce the final report. Identifying semantic differences between preliminary and final reports is essential for junior doctors, both as a training tool and to help uncover gaps in clinical knowledge. While AI in radiology is a rapidly growing field, the application of large language models (LLMs) remains challenging due to the need for specialised domain knowledge. In this paper, we explore the ability of LLMs to provide explainable and accurate comparisons of reports in the radiology domain. We begin by comparing the performance of several LLMs in comparing radiology reports. We then assess a more traditional approach based on Named-Entity-Recognition (NER). However, both approaches exhibit limitations in delivering accurate feedback on semantic similarity. To address this, we propose Llama-EntScore, a semantic similarity scoring method using a combination of Llama 3.1 and NER with tunable weights to emphasise or de-emphasise specific types of differences. Our approach generates a quantitative similarity score for tracking progress and also gives an interpretation of the score that aims to offer valuable guidance in reviewing and refining their reporting. We find our method achieves 67% exact-match accuracy and 93% accuracy within +/- 1 when compared to radiologist-provided ground truth scores - outperforming both LLMs and NER used independently. Code is available at: https://github.com/otmive/llama_reports

Compositional generalization, the ability to generate novel combinations of known concepts, is a key ingredient for visual generative models. Yet, not all mechanisms that enable or inhibit it are fully understood. In this work, we conduct a systematic study of how various design choices influence compositional generalization in image and video generation in a positive or negative way. Through controlled experiments, we identify two key factors: (i) whether the training objective operates on a discrete or continuous distribution, and (ii) to what extent conditioning provides information about the constituent concepts during training. Building on these insights, we show that relaxing the MaskGIT discrete loss with an auxiliary continuous JEPA-based objective can improve compositional performance in discrete models like MaskGIT.

With the rapid advancement of AI-generated videos, there is an urgent need for effective detection tools to mitigate societal risks such as misinformation and reputational harm. In addition to accurate classification, it is essential that detection models provide interpretable explanations to ensure transparency for regulators and end users. To address these challenges, we introduce VidGuard-R1, the first video authenticity detector that fine-tunes a multi-modal large language model (MLLM) using group relative policy optimization (GRPO). Our model delivers both highly accurate judgments and insightful reasoning. We curate a challenging dataset of 140k real and AI-generated videos produced by state-of-the-art generation models, carefully designing the generation process to maximize discrimination difficulty. We then fine-tune Qwen-VL using GRPO with two specialized reward models that target temporal artifacts and generation complexity. Extensive experiments demonstrate that VidGuard-R1 achieves state-of-the-art zero-shot performance on existing benchmarks, with additional training pushing accuracy above 95%. Case studies further show that VidGuard-R1 produces precise and interpretable rationales behind its predictions. The code is publicly available at https://VidGuard-R1.github.io.