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 Deep Learning


DePLM: Denoising Protein Language Models for Property Optimization Zeyuan Wang 1,2 Keyan Ding 2 Ming Qin 1,2 Xiaotong Li1,2

Neural Information Processing Systems

Protein optimization is a fundamental biological task aimed at enhancing the performance of proteins by modifying their sequences. Computational methods primarily rely on evolutionary information (EI) encoded by protein language models (PLMs) to predict fitness landscape for optimization. However, these methods suffer from a few limitations.








TableRAG: Million-Token Table Understanding with Language Models Si-An Chen

Neural Information Processing Systems

This enables more efficient data encoding and precise retrieval, significantly reducing prompt lengths and mitigating information loss. We have developed two new million-token benchmarks from the Arcade and BIRD-SQL datasets to thoroughly evaluate TableRAG's effectiveness at scale.



Full-Atom Peptide Design with Geometric Latent Diffusion

Neural Information Processing Systems

Peptides are short chains of amino acids and acts as vital mediators of many protein-protein interactions in human cells.