Electroencephalography (EEG) is an extensively-used and well-studied technique in the field of medical diagnostics and treatment for brain disorders, including epilepsy, migraines, and tumors. The analysis and interpretation of EEGs require physicians to have specialized training, which is not common even among most doctors in the developed world, let alone the developing world where physician shortages plague society. This problem can be addressed by teleEEG that uses remote EEG analysis by experts or by local computer processing of EEGs. However, both of these options are prohibitively expensive and the second option requires abundant computing resources and infrastructure, which is another concern in developing countries where there are resource constraints on capital and computing infrastructure. In this work, we present a cloud-based deep neural network approach to provide decision support for non-specialist physicians in EEG analysis and interpretation. Named `neurology-as-a-service,' the approach requires almost no manual intervention in feature engineering and in the selection of an optimal architecture and hyperparameters of the neural network. In this study, we deploy a pipeline that includes moving EEG data to the cloud and getting optimal models for various classification tasks. Our initial prototype has been tested only in developed world environments to-date, but our intention is to test it in developing world environments in future work. We demonstrate the performance of our proposed approach using the BCI2000 EEG MMI dataset, on which our service attains 63.4% accuracy for the task of classifying real vs. imaginary activity performed by the subject, which is significantly higher than what is obtained with a shallow approach such as support vector machines.

Deep neural networks are widely used for classification. These deep models often suffer from a lack of interpretability -- they are particularly difficult to understand because of their non-linear nature. As a result, neural networks are often treated as "black box" models, and in the past, have been trained purely to optimize the accuracy of predictions. In this work, we create a novel network architecture for deep learning that naturally explains its own reasoning for each prediction. This architecture contains an autoencoder and a special prototype layer, where each unit of that layer stores a weight vector that resembles an encoded training input. The encoder of the autoencoder allows us to do comparisons within the latent space, while the decoder allows us to visualize the learned prototypes. The training objective has four terms: an accuracy term, a term that encourages every prototype to be similar to at least one encoded input, a term that encourages every encoded input to be close to at least one prototype, and a term that encourages faithful reconstruction by the autoencoder. The distances computed in the prototype layer are used as part of the classification process. Since the prototypes are learned during training, the learned network naturally comes with explanations for each prediction, and the explanations are loyal to what the network actually computes.

A latent-variable model is introduced for text matching, inferring sentence representations by jointly optimizing generative and discriminative objectives. To alleviate typical optimization challenges in latent-variable models for text, we employ deconvolutional networks as the sequence decoder (generator), providing learned latent codes with more semantic information and better generalization. Our model, trained in an unsupervised manner, yields stronger empirical predictive performance than a decoder based on Long Short-Term Memory (LSTM), with less parameters and considerably faster training. Further, we apply it to text sequence-matching problems. The proposed model significantly outperforms several strong sentence-encoding baselines, especially in the semi-supervised setting.

We propose an automatic method to infer high dynamic range illumination from a single, limited field-of-view, low dynamic range photograph of an indoor scene. In contrast to previous work that relies on specialized image capture, user input, and/or simple scene models, we train an end-to-end deep neural network that directly regresses a limited field-of-view photo to HDR illumination, without strong assumptions on scene geometry, material properties, or lighting. We show that this can be accomplished in a three step process: 1) we train a robust lighting classifier to automatically annotate the location of light sources in a large dataset of LDR environment maps, 2) we use these annotations to train a deep neural network that predicts the location of lights in a scene from a single limited field-of-view photo, and 3) we fine-tune this network using a small dataset of HDR environment maps to predict light intensities. This allows us to automatically recover high-quality HDR illumination estimates that significantly outperform previous state-of-the-art methods. Consequently, using our illumination estimates for applications like 3D object insertion, we can achieve results that are photo-realistic, which is validated via a perceptual user study.

Many events occur in the world. Some event types are stochastically excited or inhibited---in the sense of having their probabilities elevated or decreased---by patterns in the sequence of previous events. Discovering such patterns can help us predict which type of event will happen next and when. We model streams of discrete events in continuous time, by constructing a neurally self-modulating multivariate point process in which the intensities of multiple event types evolve according to a novel continuous-time LSTM. This generative model allows past events to influence the future in complex and realistic ways, by conditioning future event intensities on the hidden state of a recurrent neural network that has consumed the stream of past events. Our model has desirable qualitative properties. It achieves competitive likelihood and predictive accuracy on real and synthetic datasets, including under missing-data conditions.

Natural gradient descent is an optimization method traditionally motivated from the perspective of information geometry, and works well for many applications as an alternative to stochastic gradient descent. In this paper we critically analyze this method and its properties, and show how it can be viewed as a type of approximate 2nd-order optimization method, where the Fisher information matrix can be viewed as an approximation of the Hessian. This perspective turns out to have significant implications for how to design a practical and robust version of the method. Additionally, we make the following contributions to the understanding of natural gradient and 2nd-order methods: a thorough analysis of the convergence speed of stochastic natural gradient descent (and more general stochastic 2nd-order methods) as applied to convex quadratics, a critical examination of the oft-used "empirical" approximation of the Fisher matrix, and an analysis of the (approximate) parameterization invariance property possessed by natural gradient methods, which we show still holds for certain choices of the curvature matrix other than the Fisher, but notably not the Hessian.

Training deep neural networks for solving machine learning problems is one great challenge in the field, mainly due to its associated optimisation problem being highly non-convex. Recent developments have suggested that many training algorithms do not suffer from undesired local minima under certain scenario, and consequently led to great efforts in pursuing mathematical explanations for such observations. This work provides an alternative mathematical understanding of the challenge from a smooth optimisation perspective. By assuming exact learning of finite samples, sufficient conditions are identified via a critical point analysis to ensure any local minimum to be globally minimal as well. Furthermore, a state of the art algorithm, known as the Generalised Gauss-Newton (GGN) algorithm, is rigorously revisited as an approximate Newton's algorithm, which shares the property of being locally quadratically convergent to a global minimum under the condition of exact learning.

Robots assisting the disabled or elderly must perform complex manipulation tasks and must adapt to the home environment and preferences of their user. Learning from demonstration is a promising choice, that would allow the non-technical user to teach the robot different tasks. However, collecting demonstrations in the home environment of a disabled user is time consuming, disruptive to the comfort of the user, and presents safety challenges. It would be desirable to perform the demonstrations in a virtual environment. In this paper we describe a solution to the challenging problem of behavior transfer from virtual demonstration to a physical robot. The virtual demonstrations are used to train a deep neural network based controller, which is using a Long Short Term Memory (LSTM) recurrent neural network to generate trajectories. The training process uses a Mixture Density Network (MDN) to calculate an error signal suitable for the multimodal nature of demonstrations. The controller learned in the virtual environment is transferred to a physical robot (a Rethink Robotics Baxter). An off-the-shelf vision component is used to substitute for geometric knowledge available in the simulation and an inverse kinematics module is used to allow the Baxter to enact the trajectory. Our experimental studies validate the three contributions of the paper: (1) the controller learned from virtual demonstrations can be used to successfully perform the manipulation tasks on a physical robot, (2) the LSTM+MDN architectural choice outperforms other choices, such as the use of feedforward networks and mean-squared error based training signals and (3) allowing imperfect demonstrations in the training set also allows the controller to learn how to correct its manipulation mistakes.

In 2013 Bagnall wrote a Gstreamer plug-in that used a recurrent neural network (RNN) to generate video in imitation of a program it was watching. Pretty soon the same RNN library was being used in another Gstreamer plug-in to classify speech on the radio according to language, and to detect birds by listening for their calls (the language classification is quite accurate and runs at 1500 faster than real time on an old laptop, which is at least a data-point for those wondering about spying capabilities). The RNN has also been used to generate text and code, and to classify text by language and author at a fine-grained level. He shows how the RNN is trained, and how it might be adapted for other forms of time-series data. He demonstrates the various plug-ins and text utilities and, for excitement, execute RNN-generated code on the fly.

When we talk about artificial intelligence in medicine, we often debate whether machines will replace tasks doctors do today. A more tantalizing possibility is performing tasks doctors can't--using large data sets, and modern computational tools like deep learning, to recognize patterns too subtle for any human to discern. Today, we're presenting early clinical results showing Cardiogram's deep neural network, DeepHeart, can do just that: recognize hypertension and sleep apnea from wearable heart rate sensors with 82% and 90% accuracy, respectively [1]. The American Heart Association is highlighting this work, conducted in partnership with the UC San Francisco's Health eHeart Study, as one of three Best Abstracts in Health Tech at their annual AHA Scientific Sessions, a meeting of roughly 18,000 cardiologists. Globally, 1.1 billion people have hypertension (chronic high blood pressure) and 1 in 5 are undiagnosed.