Department of Biomedical Data Science, Stanford University, Stanford, California, USA Labeling training datasets has become a key barrier to building medical machine learning models. One strategy is to generate training labels programmatically, for example by applying natural language processing pipelines to text reports associated with imaging studies. We propose cross-modal data programming, which generalizes this intuitive strategy in a theoretically-grounded way that enables simpler, clinician-driven input, reduces required labeling time, and improves with additional unlabeled data. In this approach, clinicians generate training labels for models defined over a target modality (e.g. The resulting technical challenge consists of estimating the accuracies and correlations of these rules; we extend a recent unsupervised generative modeling technique to handle this cross-modal setting in a provably consistent way. Across four applications in radiography, computed tomography, and electroencephalography, and using only several hours of clinician time, our approach matches or exceeds the efficacy of physician-months of hand-labeling with statistical significance, demonstrating a fundamentally faster and more flexible way of building machine learning models in medicine. In addition to being extremely costly, these training sets are inflexible: given a new classification schema, imaging system, patient population, or other change in the data distribution or modeling task, the training set generally needs to be relabeled from scratch. One manifestation of this shift in the broader machine learning community is the increasing use of weak supervision approaches, where training data is labeled in noisier, higher-level, often programmatic ways, rather than manually by experts. We broadly characterize these methods as cross-modal weak supervision approaches, in which the strategy is to programmatically extract labels from an auxiliary modality--e.g. the unstructured text reports accompanying an imaging study--which are then used as training labels for a model defined over the target modality, e.g. These methods follow the intuition that programmatically extracting labels from the auxiliary modality can be far faster and easier than hand-labeling or deriving labels from the target modality directly.

Diversity plays a vital role in many text generating applications. In recent years, Conditional Variational Auto Encoders (CVAE) have shown promising performances for this task. However, they often encounter the so called KL-Vanishing problem. Previous works mitigated such problem by heuristic methods such as strengthening the encoder or weakening the decoder while optimizing the CVAE objective function. Nevertheless, the optimizing direction of these methods are implicit and it is hard to find an appropriate degree to which these methods should be applied. In this paper, we propose an explicit optimizing objective to complement the CVAE to directly pull away from KL-vanishing. In fact, this objective term guides the encoder towards the "best encoder" of the decoder to enhance the expressiveness. A labeling network is introduced to estimate the "best encoder". It provides a continuous label in the latent space of CVAE to help build a close connection between latent variables and targets. The whole proposed method is named Self Labeling CVAE~(SLCVAE). To accelerate the research of diverse text generation, we also propose a large native one-to-many dataset. Extensive experiments are conducted on two tasks, which show that our method largely improves the generating diversity while achieving comparable accuracy compared with state-of-art algorithms.

Deep neural networks have recently achieved tremendous success in image classification. Recent studies have however shown that they are easily misled into incorrect classification decisions by adversarial examples. Adversaries can even craft attacks by querying the model in black-box settings, where no information about the model is released except its final decision. Such decision-based attacks usually require lots of queries, while real-world image recognition systems might actually restrict the number of queries. In this paper, we propose qFool, a novel decision-based attack algorithm that can generate adversarial examples using a small number of queries. The qFool method can drastically reduce the number of queries compared to previous decision-based attacks while reaching the same quality of adversarial examples. We also enhance our method by constraining adversarial perturbations in low-frequency subspace, which can make qFool even more computationally efficient. Altogether, we manage to fool commercial image recognition systems with a small number of queries, which demonstrates the actual effectiveness of our new algorithm in practice.

Short-term load forecasting (STLF) is essential for the reliable and economic operation of power systems. Though many STLF methods were proposed over the past decades, most of them focused on loads at high aggregation levels only. Thus, low-aggregation load forecast still requires further research and development. Compared with the substation or city level loads, individual loads are typically more volatile and much more challenging to forecast. To further address this issue, this paper first discusses the characteristics of small-and-medium enterprise (SME) and residential loads at different aggregation levels and quantifies their predictability with approximate entropy. Various STLF techniques, from the conventional linear regression to state-of-the-art deep learning, are implemented for a detailed comparative analysis to verify the forecasting performances as well as the predictability using an Irish smart meter dataset. In addition, the paper also investigates how using data processing improves individual-level residential load forecasting with low predictability. Effectiveness of the discussed method is validated with numerical results.

Quantization, a commonly used technique to reduce the memory footprint of a neural network for edge computing, entails reducing the precision of the floating-point representation used for the parameters of the network. The impact of such rounding-off errors on the overall performance of the neural network is estimated using testing, which is not exhaustive and thus cannot be used to guarantee the safety of the model. We present a framework based on Satisfiability Modulo Theory (SMT) solvers to quantify the robustness of neural networks to parameter perturbation. To this end, we introduce notions of local and global robustness that capture the deviation in the confidence of class assignments due to parameter quantization. The robustness notions are then cast as instances of SMT problems and solved automatically using solvers, such as dReal. We demonstrate our framework on two simple Multi-Layer Perceptrons (MLP) that perform binary classification on a two-dimensional input. In addition to quantifying the robustness, we also show that Rectified Linear Unit activation results in higher robustness than linear activations for our MLPs.

Non-small-cell lung cancer (NSCLC) represents approximately 80-85% of lung cancer diagnoses and is the leading cause of cancer-related death worldwide. Recent studies indicate that image-based radiomics features from positron emission tomography-computed tomography (PET/CT) images have predictive power on NSCLC outcomes. To this end, easily calculated functional features such as the maximum and the mean of standard uptake value (SUV) and total lesion glycolysis (TLG) are most commonly used for NSCLC prognostication, but their prognostic value remains controversial. Meanwhile, convolutional neural networks (CNN) are rapidly emerging as a new premise for cancer image analysis, with significantly enhanced predictive power compared to other hand-crafted radiomics features. Here we show that CNN trained to perform the tumor segmentation task, with no other information than physician contours, identify a rich set of survival-related image features with remarkable prognostic value. In a retrospective study on 96 NSCLC patients before stereotactic-body radiotherapy (SBRT), we found that the CNN segmentation algorithm (U-Net) trained for tumor segmentation in PET/CT images, contained features having strong correlation with 2- and 5-year overall and disease-specific survivals. The U-net algorithm has not seen any other clinical information (e.g. survival, age, smoking history) than the images and the corresponding tumor contours provided by physicians. Furthermore, through visualization of the U-Net, we also found convincing evidence that the regions of progression appear to match with the regions where the U-Net features identified patterns that predicted higher likelihood of death. We anticipate our findings will be a starting point for more sophisticated non-intrusive patient specific cancer prognosis determination.

An online tool has been unveiled which is capable of bringing black and white photographs to life instantaneously by adding colour to them using artificial intelligence. Colourisation of old images is a normally time consuming process which requires specialist training and expensive software. The tool, ColouriseSG, is able to do it for free from only a single digital image and works on iconic historical photographs and old family portraits. Try it for yourself here or via the interactive tool below. The artificial intelligence is able to colourise images for free from only a single digital image and works on iconic historical photographs and old family portraits.

If you have recently started doing work in deep learning, especially image recognition, you might have seen the abundance of blog posts all over the internet, promising to teach you how to build a world-class image classifier in a dozen or fewer lines and just a few minutes on a modern GPU. What's shocking is not the promise but the fact that most of these tutorials end up delivering on it. To those trained in'conventional' machine learning techniques, the very idea that a model developed for one data set could simply be applied to a different one sounds absurd. The answer is, of course, transfer learning, one of the most fascinating features of deep neural networks. In this post, we'll first look at what transfer learning is, when it will work, when it might work, and why it won't work in some cases, finally concluding with some pointers at best practices for transfer learning.

While deep neural networks are all the rage, the complexity of the major frameworks has been a barrier to their use for developers new to machine learning. There have been several proposals for improved and simplified high-level APIs for building neural network models, all of which tend to look similar from a distance but show differences on closer examination. Keras is one of the leading high-level neural networks APIs. It is written in Python and supports multiple back-end neural network computation engines. Given that the TensorFlow project has adopted Keras as the high-level API for the upcoming TensorFlow 2.0 release, Keras looks to be a winner, if not necessarily the winner.

As a global, public communications platform, Twitter strives to keep users informed with relevant, healthy content. Originally, Twitter presented Tweets in reverse-chronological order. As the community became more connected, the amount of content in users' home timelines increased significantly. Users would follow hundreds of people on Twitter -- maybe thousands -- and when opening Twitter, they would miss some of their most important Tweets. To address this issue, we launched a "Ranked Timeline" which shows the most relevant Tweets at the top of the timeline -- ensuring users never miss their best Tweets. A year later we shared how machine learning powers the ranked timeline at scale.