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Deep learning enables rapid identification of potent DDR1 kinase inhibitors

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Non-depicted distances are the same as for 3-centered pharmacophore. Non-depicted distances are the same as for 3-centered and 4-centered pharmacophores. Yellow: the reported small-molecule DDR1 inhibitor (PDB code: 5BVN).


Object Detection with 10 lines of code

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The breakthrough and rapid adoption of deep learning in 2012 brought into existence modern and highly accurate object detection algorithms and methods such as R-CNN, Fast-RCNN, Faster-RCNN, RetinaNet and fast yet highly accurate ones like SSD and YOLO. Using these methods and algorithms, based on deep learning which is also based on machine learning require lots of mathematical and deep learning frameworks understanding. There are millions of expert computer programmers and software developers that want to integrate and create new products that uses object detection. But this technology is kept out of their reach due to the extra and complicated path to understanding and making practical use of it.


Top 7 Machine Learning Methods that Every Data Scientist Must Know

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In this digital era, now most of the manual tasks are being automated. Now, machine learning algorithms are helping computers perform surgeries, play chess, and getting smarter and more personal. We are living in a world of constant progress on the technological ground, and looking at how computing is getting advanced day after day. We can also predict what is to come in the days ahead. The algorithm of machine learning, also called model is a mathematical expression that represents information or data in the context of any particular problem, which is often a business problem. The main aim is to go from data to insight.


Novel molecules designed by artificial intelligence in 21 days are validated in mice

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September 2nd, 2019, 4 PM, London, Insilico Medicine, a global leader in artificial intelligence for drug discovery, today announced the publication of a paper titled, "Deep learning enables rapid identification of potent DDR1 kinase inhibitors," in Nature Biotechnology. The paper describes a timed challenge, where the new artificial intelligence system called Generative Tensorial Reinforcement Learning (GENTRL) designed six novel inhibitors of DDR1, a kinase target implicated in fibrosis and other diseases, in 21 days. Four compounds were active in biochemical assays, and two were validated in cell-based assays. One lead candidate was tested and demonstrated favorable pharmacokinetics in mice. The traditional drug discovery starts with the testing of thousands of small molecules in order to get to just a few lead-like molecules and only about one in ten of these molecules pass clinical trials in human patients.


How to Use Deep Learning to Clone Yourself as a Chatbot (Replika Review) Lionbridge AI

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Chatbots are one of the most common applications of natural language processing and machine learning. Replika AI has created a platform where anyone, including people with zero knowledge of machine learning, can create and train a chatbot of their own. After the tragic death of her best friend, Eugenia Kuyda (Founder of Luka inc.) used the text message and email history of her friend to recreate him as a chatbot. The feedback from other friends and family inspired her to expand the project and create Replika AI, a chatbot users train themselves. Numerous companies utilize chatbots for customer interactions, and thus chatbot training data is one of the most in-demand services in the AI industry today.


AI in healthcare: Predictive diagnostics

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When it comes to increasing the accuracy of medical diagnoses, reducing worker burnout, and providing cheaper universal healthcare, AI seems like a natural solution. AI appears to have secured a prominent role in the medical industry as both entrepreneurs and policymakers extol the immense potential in incorporating machine learning and deep neural networks into a doctor's daily routine. Decades worth of medical data collected from every appointment, procedure, and survey sit untouched in databases while algorithms wait hungrily for training data. Prominent applications of AI in predictive diagnostics lie in image-based diagnostics and preemptive predictions through machine learning. Amidst the bustling excitement over the applications of AI in healthcare, the medical industry maintains its slow and sluggish pace in adopting new technologies.


Stock Market Prediction LSTM GRU can Change your Life of Stock Market Tensorflow keras

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Another application of Deep learning Using RNN on Stocks market prediction. I named this model "How 4 lines SimpleRNN can change your Life". This model is of only four lines and its prediction accuracy is 99.575%, this is how deep learning is changing the world. If you like my video, then please subscribe to my YouTube Channel. Here is the Link: https://www.youtube.com/channel/UCnGz... Please do like, share and leave your comments on my videos.


The simple essence of automatic differentiation

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Automatic differentiation (AD) in reverse mode (RAD) is a central component of deep learning and other uses of large-scale optimization. Commonly used RAD algorithms such as backpropagation, however, are complex and stateful, hindering deep understanding, improvement, and parallel execution. This paper develops a simple, generalized AD algorithm calculated from a simple, natural specification. The general algorithm is then specialized by varying the representation of derivatives. In particular, applying well-known constructions to a naive representation yields two RAD algorithms that are far simpler than previously known.


Facebook Reveals 'ELF' OpenGo Bot Code After Being 'Inspired' By DeepMind

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Mike Schroepfer, Facebook CTO speaks during the second day of the Web Summit in Lisbon, Portugal on November 8, 2016. Facebook and Google DeepMind's race to create an artificial intelligence (AI) that could beat professional players at the ancient Chinese board game of Go has been no secret. Mastering Go -- one of the most complex games on the planet for computers to excel at due to the sheer number of possible moves -- has been the dream of AI researchers for decades but only recently did big tech firms like Facebook and Google start throwing millions of dollars at the cause in the hope that it will lead to further breakthroughs. DeepMind arguably won the race in March 2016 when its AlphaGo AI agent beat Lee Sedol, one of the best Go players ever, by four games to one. But Facebook's "ELF" OpenGo bot isn't far behind now -- it too has defeated world champion and professional Go players.


U.S. Patent and Trademark Office wants your opinion on AI inventions

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The U.S. Department of Commerce's Patent and Trademark Office (USPTO) is asking for the help of experts and the broader public to determine the impact AI will have on intellectual property and "whether new forms of intellectual property protection are needed." A call for public comment was published in the Federal Registrar by the USPTO today in search of answers about such issues as how AI is reshaping perceptions of inventions or whether additional information should be required to claim a deep learning system as an invention since they can have a large number of hidden layers and weights that evolve. To help solicit responses, the notice in the federal registrar comes along with a series of questions such as "what is an AI invention and what does it contain?" "What are the different ways that a natural person can contribute to conception of an AI invention and be eligible to be a named inventor? Structuring data in order to train a model?