Sleep staging is a crucial task for diagnosing sleep disorders. It is tedious and complex as it can take a trained expert several hours to annotate just one patient's polysomnogram (PSG) from a single night. Although deep learning models have demonstrated state-of-the-art performance in automating sleep staging, interpretability which defines other desiderata, has largely remained unexplored. In this study, we propose Sleep staging via Prototypes from Expert Rules (SLEEPER), which combines deep learning models with expert defined rules using a prototype learning framework to generate simple interpretable models. In particular, SLEEPER utilizes sleep scoring rules and expert defined features to derive prototypes which are embeddings of PSG data fragments via convolutional neural networks. The final models are simple interpretable models like a shallow decision tree defined over those phenotypes. We evaluated SLEEPER using two PSG datasets collected from sleep studies and demonstrated that SLEEPER could provide accurate sleep stage classification comparable to human experts and deep neural networks with about 85% ROC-AUC and .7 kappa.

To coordinate actions with an interaction partner requires a constant exchange of sensorimotor signals. Humans acquire these skills in infancy and early childhood mostly by imitation learning and active engagement with a skilled partner. They require the ability to predict and adapt to one's partner during an interaction. In this work we want to explore these ideas in a human-robot interaction setting in which a robot is required to learn interactive tasks from a combination of observational and kinesthetic learning. To this end, we propose a deep learning framework consisting of a number of components for (1) human and robot motion embedding, (2) motion prediction of the human partner and (3) generation of robot joint trajectories matching the human motion. To test these ideas, we collect human-human interaction data and human-robot interaction data of four interactive tasks "hand-shake", "hand-wave", "parachute fist-bump" and "rocket fist-bump". We demonstrate experimentally the importance of predictive and adaptive components as well as low-level abstractions to successfully learn to imitate human behavior in interactive social tasks.

The Fisher information matrix (FIM) plays an essential role in statistics and machine learning as a Riemannian metric tensor. Focusing on the FIM and its variants in deep neural networks (DNNs), we reveal their characteristic behavior when the network is sufficiently wide and has random weights and biases. Various FIMs asymptotically show pathological eigenvalue spectra in the sense that a small number of eigenvalues take on large values while most of them are close to zero. This implies that the local shape of the parameter space or loss landscape is very steep in a few specific directions and almost flat in the other directions. Similar pathological spectra appear in other variants of FIMs: one is the neural tangent kernel; another is a metric for the input signal and feature space that arises from feedforward signal propagation. The quantitative understanding of the FIM and its variants provided here offers important perspectives on learning and signal processing in large-scale DNNs.

The breakthrough of deep Q-Learning on different types of environments revolutionized the algorithmic design of Reinforcement Learning to introduce more stable and robust algorithms, to that end many extensions to deep Q-Learning algorithm have been proposed to reduce the variance of the target values and the overestimation phenomena. In this paper, we examine new methodology to solve these issues, we propose using Dropout techniques on deep Q-Learning algorithm as a way to reduce variance and overestimation. We further present experiments on some of the benchmark environments that demonstrate significant improvement of the stability of the performance and a reduction in variance and overestimation.

Satellite imaging is a critical technology for monitoring and responding to natural disasters such as flooding. Despite the capabilities of modern satellites, there is still much to be desired from the perspective of first response organisations like UNICEF. Two main challenges are rapid access to data, and the ability to automatically identify flooded regions in images. We describe a prototypical flood segmentation system, identifying cloud, water and land, that could be deployed on a constellation of small satellites, performing processing on board to reduce downlink bandwidth by 2 orders of magnitude. We target PhiSat-1, part of the FSSCAT mission, which is planned to be launched by the European Space Agency (ESA) near the start of 2020 as a proof of concept for this new technology.

Deep neural networks are vulnerable to adversarial attacks and hard to interpret because of their black-box nature. The recently proposed invertible network is able to accurately reconstruct the inputs to a layer from its outputs, thus has the potential to unravel the black-box model. An invertible network classifier can be viewed as a two-stage model: (1) invertible transformation from input space to the feature space; (2) a linear classifier in the feature space. We can determine the decision boundary of a linear classifier in the feature space; since the transform is invertible, we can invert the decision boundary from the feature space to the input space. Furthermore, we propose to determine the projection of a data point onto the decision boundary, and define explanation as the difference between data and its projection. Finally, we propose to locally approximate a neural network with its first-order Taylor expansion, and define feature importance using a local linear model. We provide the implementation of our method: \url{https://github.com/juntang-zhuang/explain_invertible}.

Distributed representations have been used to support downstream tasks in healthcare recently. Healthcare data (e.g., electronic health records) contain multiple modalities of data from heterogeneous sources that can provide complementary information, alongside an added dimension to learning personalized patient representations. To this end, in this paper we propose a novel unsupervised encoder-decoder model, namely Mixed Pooling Multi-View Attention Autoencoder (MPVAA), that generates patient representations encapsulating a holistic view of their medical profile. Specifically, by first learning personalized graph embeddings pertaining to each patient's heterogeneous healthcare data, it then integrates the non-linear relationships among them into a unified representation through multi-view attention mechanism. Additionally, a mixed pooling strategy is incorporated in the encoding step to learn diverse information specific to each data modality. Experiments conducted for multiple tasks demonstrate the effectiveness of the proposed model over the state-of-the-art representation learning methods in healthcare.

It is common for pathologists to annotate specific regions of the tissue, such as tumor, directly on the glass slide with markers. Although this practice was helpful prior to the advent of histology whole slide digitization, it often occludes important details which are increasingly relevant to immuno-oncology due to recent advancements in digital pathology imaging techniques. The current work uses a generative adversarial network with cycle loss to remove these annotations while still maintaining the underlying structure of the tissue by solving an image-to-image translation problem. We train our network on up to 300 whole slide images with marker inks and show that 70% of the corrected image patches are indistinguishable from originally uncontaminated image tissue to a human expert. This portion increases 97% when we replace the human expert with a deep residual network. We demonstrated the fidelity of the method to the original image by calculating the correlation between image gradient magnitudes. We observed a revival of up to 94,000 nuclei per slide in our dataset, the majority of which were located on tissue border.

Controversial claims are abundant in online media and discussion forums. A better understanding of such claims requires analyzing them from different perspectives. Stance classification is a necessary step for inferring these perspectives in terms of supporting or opposing the claim. In this work, we present a neural network model for stance classification leveraging BERT representations and augmenting them with a novel consistency constraint. Experiments on the Perspectrum dataset, consisting of claims and users' perspectives from various debate websites, demonstrate the effectiveness of our approach over state-of-the-art baselines.

Code summarization (CS) and code generation (CG) are two crucial tasks in the field of automatic software development. Various neural network-based approaches are proposed to solve these two tasks separately. However, there exists a specific intuitive correlation between CS and CG, which have not been exploited in previous work. In this paper, we apply the relations between two tasks to improve the performance of both tasks. In other words, exploiting the duality between the two tasks, we propose a dual training framework to train the two tasks simultaneously. In this framework, we consider the dualities on probability and attention weights, and design corresponding regularization terms to constrain the duality. We evaluate our approach on two datasets collected from GitHub, and experimental results show that our dual framework can improve the performance of CS and CG tasks over baselines.