The integration of Artificial Intelligence (AI) in Network Intrusion Detection Systems (NIDS) is a promising approach to tackle the increasing sophistication of cyberattacks. However, since Machine Learning (ML) and Deep Learning (DL) models rely heavily on the quality of their training data, the lack of diverse and up-to-date datasets hinders their generalization capability to detect malicious activity in previously unseen network traffic. This study presents an experimental validation of the reliability of the GeNIS dataset for AI-based NIDS, to serve as a baseline for future benchmarks. Five feature selection methods, Information Gain, Chi-Squared Test, Recursive Feature Elimination, Mean Absolute Deviation, and Dispersion Ratio, were combined to identify the most relevant features of GeNIS and reduce its dimensionality, enabling a more computationally efficient detection. Three decision tree ensembles and two deep neural networks were trained for both binary and multiclass classification tasks. All models reached high accuracy and F1-scores, and the ML ensembles achieved slightly better generalization while remaining more efficient than DL models. Overall, the obtained results indicate that the GeNIS dataset supports intelligent intrusion detection and cy-berattack classification with time-based and quantity-based behavioral features.

We investigate a number of Artificial Neural Network architectures (well-known and more ``exotic'') in application to the long-term financial time-series forecasts of indexes on different global markets. The particular area of interest of this research is to examine the correlation of these indexes' behaviour in terms of Machine Learning algorithms cross-training. Would training an algorithm on an index from one global market produce similar or even better accuracy when such a model is applied for predicting another index from a different market? The demonstrated predominately positive answer to this question is another argument in favour of the long-debated Efficient Market Hypothesis of Eugene Fama.

Accepted at CISP-BMEI 2025 Abstract--Early and accurate detection of cardiac arrhythmias is vital for timely diagnosis and intervention. We propose a lightweight deep learning model combining 1D Convolutional Neural Networks (CNN), attention mechanisms, and Bidirectional Long Short-T erm Memory (BiLSTM) for classifying arrhythmias from both 12-lead and single-lead ECGs. Evaluated on the CPSC 2018 dataset, the model addresses class imbalance using a class-weighted loss and demonstrates superior accuracy and F1-scores over baseline models. With only 0.945 million parameters, our model is well-suited for real-time deployment in wearable health monitoring systems. The source code is available at https://github.com/infocusp/tiny Cardiovascular diseases (CVDs) remain the leading cause of morbidity and mortality worldwide, accounting for approximately 17.9 million deaths each year according to the World Health Organization (WHO) [1]. Electrocardiography (ECG) is a simple yet effective technique for detecting arrhythmias.

Chimeric antigen receptor T-cell (CAR-T) therapy represents a paradigm shift in cancer treatment, yet development timelines of 8-12 years and clinical attrition rates exceeding 40-60% highlight critical inefficiencies in target selection, safety assessment, and molecular optimization. We present Bio AI Agent, a multi-agent artificial intelligence system powered by large language models that enables autonomous CAR-T development through collaborative specialized agents. The system comprises six autonomous agents: Target Selection Agent for multi-parametric antigen prioritization across >10,000 cancer-associated targets, Toxicity Prediction Agent for comprehensive safety profiling integrating tissue expression atlases and pharmacovigilance databases, Molecular Design Agent for rational CAR engineering, Patent Intelligence Agent for freedom-to-operate analysis, Clinical Translation Agent for regulatory compliance, and Decision Orchestration Agent for multi-agent coordination. Retrospective validation demonstrated autonomous identification of high-risk targets including FcRH5 (hepatotoxicity) and CD229 (off-tumor toxicity), patent infringement risks for CD38+SLAMF7 combinations, and generation of comprehensive development roadmaps. By enabling parallel processing, specialized reasoning, and autonomous decision-making superior to monolithic AI systems, Bio AI Agent addresses critical gaps in precision oncology development and has potential to accelerate translation of next-generation immunotherapies from discovery to clinic.

Accurate fluence map prediction is essential in intensity-modulated radiation therapy (IMRT) to maximize tumor coverage while minimizing dose to healthy tissues. Conventional optimization is time-consuming and dependent on planner expertise. This study presents a deep learning framework that accelerates fluence map generation while maintaining clinical quality. An end-to-end 3D Swin-UNETR network was trained to predict nine-beam fluence maps directly from volumetric CT images and anatomical contours using 99 prostate IMRT cases (79 for training and 20 for testing). The transformer-based model employs hierarchical self-attention to capture both local anatomical structures and long-range spatial dependencies. Predicted fluence maps were imported into the Eclipse Treatment Planning System for dose recalculation, and model performance was evaluated using beam-wise fluence correlation, spatial gamma analysis, and dose-volume histogram (DVH) metrics. The proposed model achieved an average R^2 of 0.95 +/- 0.02, MAE of 0.035 +/- 0.008, and gamma passing rate of 85 +/- 10 percent (3 percent / 3 mm) on the test set, with no significant differences observed in DVH parameters between predicted and clinical plans. The Swin-UNETR framework enables fully automated, inverse-free fluence map prediction directly from anatomical inputs, enhancing spatial coherence, accuracy, and efficiency while offering a scalable and consistent solution for automated IMRT plan generation.

Accident anticipation is essential for proactive and safe autonomous driving, where even a brief advance warning can enable critical evasive actions. However, two key challenges hinder real-world deployment: (1) noisy or degraded sensory inputs from weather, motion blur, or hardware limitations, and (2) the need to issue timely yet reliable predictions that balance early alerts with false-alarm suppression. We propose a unified framework that integrates diffusion-based denoising with a time-aware actor-critic model to address these challenges. The diffusion module reconstructs noise-resilient image and object features through iterative refinement, preserving critical motion and interaction cues under sensor degradation. In parallel, the actor-critic architecture leverages long-horizon temporal reasoning and time-weighted rewards to determine the optimal moment to raise an alert, aligning early detection with reliability. Experiments on three benchmark datasets (DAD, CCD, A3D) demonstrate state-of-the-art accuracy and significant gains in mean time-to-accident, while maintaining robust performance under Gaussian and impulse noise. Qualitative analyses further show that our model produces earlier, more stable, and human-aligned predictions in both routine and highly complex traffic scenarios, highlighting its potential for real-world, safety-critical deployment.

Worldwide, suicide is the second leading cause of death for adolescents with past suicide attempts to be an important predictor for increased future suicides. While some people with suicidal thoughts may try to suppress them, many signal their intentions in social media platforms. To address these issues, we propose a new type of hybrid deep learning scheme, i.e., the combination of a CNN architecture and a BiGRU technique, which can accurately identify the patterns of suicidal ideation from SN datasets. Also, we apply Explainable AI methods using SHapley Additive exPlanations to interpret the prediction results and verifying the model reliability. This integration of CNN local feature extraction, BiGRU bidirectional sequence modeling, attention mechanisms, and SHAP interpretability provides a comprehensive framework for suicide detection. Training and evaluation of the system were performed on a publicly available dataset. Several performance metrics were used for evaluating model performance. Our method was found to have achieved 93.97 accuracy in experimental results. Comparative study to different state-of-the-art Machine Learning and DL models and existing literature demonstrates the superiority of our proposed technique over all the competing methods.

Designing impactful educational technologies in contexts of socio-political instability requires a nuanced understanding of educational aspirations. Currently, scalable metrics for measuring aspirations are limited. This study adapts, translates, and evaluates Snyder's Hope Scale as a metric for measuring aspirations among 136 women learning programming online during a period of systemic educational restrictions in Afghanistan. The adapted scale demonstrated good reliability (Cronbach's α = 0.78) and participants rated it as understandable and relevant. While overall aspiration-related scores did not differ significantly by access to Large Language Models (LLMs), those with access reported marginally higher scores on the Avenues subscale (p = .056), suggesting broader perceived pathways to achieving educational aspirations. These findings support the use of the adapted scale as a metric for aspirations in contexts of socio-political instability. More broadly, the adapted scale can be used to evaluate the impact of aspiration-driven design of educational technologies.

The financial industry's growing demand for advanced natural language processing (NLP) capabilities has highlighted the limitations of generalist large language models (LLMs) in handling domain-specific financial tasks. To address this gap, we introduce the LLM Pro Finance Suite, a collection of five instruction-tuned LLMs (ranging from 8B to 70B parameters) specifically designed for financial applications. Our approach focuses on enhancing generalist instruction-tuned models, leveraging their existing strengths in instruction following, reasoning, and toxicity control, while fine-tuning them on a curated, high-quality financial corpus comprising over 50% finance-related data in English, French, and German. We evaluate the LLM Pro Finance Suite on a comprehensive financial benchmark suite, demonstrating consistent improvement over state-of-the-art baselines in finance-oriented tasks and financial translation. Notably, our models maintain the strong general-domain capabilities of their base models, ensuring reliable performance across non-specialized tasks. This dual proficiency, enhanced financial expertise without compromise on general abilities, makes the LLM Pro Finance Suite an ideal drop-in replacement for existing LLMs in financial workflows, offering improved domain-specific performance while preserving overall versatility. We publicly release two 8B-parameters models to foster future research and development in financial NLP applications: https://huggingface.co/collections/DragonLLM/llm-open-finance.

While Large Language Models have been used to produce interpretable stock forecasts, they mainly focus on analyzing textual reports but not historical price data, also known as Technical Analysis. This task is challenging as it switches between domains: the stock price inputs and outputs lie in the time-series domain, while the reasoning step should be in natural language. In this work, we introduce Verbal Technical Analysis (VTA), a novel framework that combine verbal and latent reasoning to produce stock time-series forecasts that are both accurate and interpretable. To reason over time-series, we convert stock price data into textual annotations and optimize the reasoning trace using an inverse Mean Squared Error (MSE) reward objective. To produce time-series outputs from textual reasoning, we condition the outputs of a time-series backbone model on the reasoning-based attributes. Experiments on stock datasets across U.S., Chinese, and European markets show that VTA achieves state-of-the-art forecasting accuracy, while the reasoning traces also perform well on evaluation by industry experts.