Deep Learning
Dream, Lift, Animate: From Single Images to Animatable Gaussian Avatars
Bühler, Marcel C., Yuan, Ye, Li, Xueting, Huang, Yangyi, Nagano, Koki, Iqbal, Umar
We introduce Dream, Lift, Animate (DLA), a novel framework that reconstructs animatable 3D human avatars from a single image. This is achieved by leveraging multi-view generation, 3D Gaussian lifting, and pose-aware UV-space mapping of 3D Gaussians. Given an image, we first dream plausible multi-views using a video diffusion model, capturing rich geometric and appearance details. These views are then lifted into unstructured 3D Gaussians. To enable animation, we propose a transformer-based encoder that models global spatial relationships and projects these Gaussians into a structured latent representation aligned with the UV space of a parametric body model. This latent code is decoded into UV-space Gaussians that can be animated via body-driven deformation and rendered conditioned on pose and viewpoint. By anchoring Gaussians to the UV manifold, our method ensures consistency during animation while preserving fine visual details. DLA enables real-time rendering and intuitive editing without requiring post-processing. Our method outperforms state-of-the-art approaches on the ActorsHQ and 4D-Dress datasets in both perceptual quality and photometric accuracy. By combining the generative strengths of video diffusion models with a pose-aware UV-space Gaussian mapping, DLA bridges the gap between unstructured 3D representations and high-fidelity, animation-ready avatars.
Assay2Mol: large language model-based drug design using BioAssay context
Deng, Yifan, Ericksen, Spencer S., Gitter, Anthony
Scientific databases aggregate vast amounts of quantitative data alongside descriptive text. In biochemistry, molecule screening assays evaluate candidate molecules' functional responses against disease targets. Unstructured text that describes the biological mechanisms through which these targets operate, experimental screening protocols, and other attributes of assays offer rich information for drug discovery campaigns but has been untapped because of that unstructured format. We present Assay2Mol, a large language model-based workflow that can capitalize on the vast existing biochemical screening assays for early-stage drug discovery. Assay2Mol retrieves existing assay records involving targets similar to the new target and generates candidate molecules using in-context learning with the retrieved assay screening data. Assay2Mol outperforms recent machine learning approaches that generate candidate ligand molecules for target protein structures, while also promoting more synthesizable molecule generation.
Lightweight Model for Poultry Disease Detection from Fecal Images Using Multi-Color Space Feature Optimization and Machine Learning
Islam, A. K. M. Shoriful, Hassan, Md. Rakib, Uddin, Macbah, Rahman, Md. Shahidur
Poultry farming is a vital component of the global food supply chain, yet it remains highly vulnerable to infectious diseases such as coccidiosis, salmonellosis, and Newcastle disease. This study proposes a lightweight machine learning-based approach to detect these diseases by analyzing poultry fecal images. We utilize multi-color space feature extraction (RGB, HSV, LAB) and explore a wide range of color, texture, and shape-based descriptors, including color histograms, local binary patterns (LBP), wavelet transforms, and edge detectors. Through a systematic ablation study and dimensionality reduction using PCA and XGBoost feature selection, we identify a compact global feature set that balances accuracy and computational efficiency. An artificial neural network (ANN) classifier trained on these features achieved 95.85% accuracy while requiring no GPU and only 638 seconds of execution time in Google Colab. Compared to deep learning models such as Xception and MobileNetV3, our proposed model offers comparable accuracy with drastically lower resource usage. This work demonstrates a cost-effective, interpretable, and scalable alternative to deep learning for real-time poultry disease detection in low-resource agricultural settings.
Sequential Attention-based Sampling for Histopathological Analysis
G, Tarun, Malpani, Naman, Thoppe, Gugan, Devarajan, Sridharan
Deep neural networks are increasingly applied in automated histopathology. Yet, whole-slide images (WSIs) are often acquired at gigapixel sizes, rendering them computationally infeasible to analyze entirely at high resolution. Diagnostic labels are largely available only at the slide-level, because expert annotation of images at a finer (patch) level is both laborious and expensive. Moreover, regions with diagnostic information typically occupy only a small fraction of the WSI, making it inefficient to examine the entire slide at full resolution. Here, we propose SASHA -- Sequential Attention-based Sampling for Histopathological Analysis -- a deep reinforcement learning approach for efficient analysis of histopathological images. First, SASHA learns informative features with a lightweight hierarchical, attention-based multiple instance learning (MIL) model. Second, SASHA samples intelligently and zooms selectively into a small fraction (10-20\%) of high-resolution patches to achieve reliable diagnoses. We show that SASHA matches state-of-the-art methods that analyze the WSI fully at high resolution, albeit at a fraction of their computational and memory costs. In addition, it significantly outperforms competing, sparse sampling methods. We propose SASHA as an intelligent sampling model for medical imaging challenges that involve automated diagnosis with exceptionally large images containing sparsely informative features. Model implementation is available at: https://github.com/coglabiisc/SASHA.
PERTINENCE: Input-based Opportunistic Neural Network Dynamic Execution
Shende, Omkar, Ananthanarayanan, Gayathri, Traiola, Marcello
Deep neural networks (DNNs) have become ubiquitous thanks to their remarkable ability to model complex patterns across various domains such as computer vision, speech recognition, robotics, etc. While large DNN models are often more accurate than simpler, lightweight models, they are also resource- and energy-hungry. Hence, it is imperative to design methods to reduce reliance on such large models without significant degradation in output accuracy. The high computational cost of these models is often necessary only for a reduced set of challenging inputs, while lighter models can handle most simple ones. Thus, carefully combining properties of existing DNN models in a dynamic, input-based way opens opportunities to improve efficiency without impacting accuracy. In this work, we introduce PERTINENCE, a novel online method designed to analyze the complexity of input features and dynamically select the most suitable model from a pre-trained set to process a given input effectively. To achieve this, we employ a genetic algorithm to explore the training space of an ML-based input dispatcher, enabling convergence towards the Pareto front in the solution space that balances overall accuracy and computational efficiency. We showcase our approach on state-of-the-art Convolutional Neural Networks (CNNs) trained on the CIFAR-10 and CIFAR-100, as well as Vision Transformers (ViTs) trained on TinyImageNet dataset. We report results showing PERTINENCE's ability to provide alternative solutions to existing state-of-the-art models in terms of trade-offs between accuracy and number of operations. By opportunistically selecting among models trained for the same task, PERTINENCE achieves better or comparable accuracy with up to 36% fewer operations.
FinStat2SQL: A Text2SQL Pipeline for Financial Statement Analysis
Nguyen, Quang Hung, Trinh, Phuong Anh, Mai, Phan Quoc Hung, Trinh, Tuan Phong
Despite the advancements of large language models, text2sql still faces many challenges, particularly with complex and domain-specific queries. In finance, database designs and financial reporting layouts vary widely between financial entities and countries, making text2sql even more challenging. We present FinStat2SQL, a lightweight text2sql pipeline enabling natural language queries over financial statements. Tailored to local standards like VAS, it combines large and small language models in a multi-agent setup for entity extraction, SQL generation, and self-correction. We build a domain-specific database and evaluate models on a synthetic QA dataset. A fine-tuned 7B model achieves 61.33\% accuracy with sub-4-second response times on consumer hardware, outperforming GPT-4o-mini. FinStat2SQL offers a scalable, cost-efficient solution for financial analysis, making AI-powered querying accessible to Vietnamese enterprises.
DCRM: A Heuristic to Measure Response Pair Quality in Preference Optimization
Recent research has attempted to associate preference optimization (PO) performance with the underlying preference datasets. In this work, our observation is that the differences between the preferred response $y^+$ and dispreferred response $y^-$ influence what LLMs can learn, which may not match the desirable differences to learn. Therefore, we use distance and reward margin to quantify these differences, and combine them to get Distance Calibrated Reward Margin (DCRM), a metric that measures the quality of a response pair for PO. Intuitively, DCRM encourages minimal noisy differences and maximal desired differences. With this, we study 3 types of commonly used preference datasets, classified along two axes: the source of the responses and the preference labeling function. We establish a general correlation between higher DCRM of the training set and better learning outcome. Inspired by this, we propose a best-of-$N^2$ pairing method that selects response pairs with the highest DCRM. Empirically, in various settings, our method produces training datasets that can further improve models' performance on AlpacaEval, MT-Bench, and Arena-Hard over the existing training sets.
Don't Pay Attention
Hammoud, Mohammad, Acharya, Devang
The Transformer has become the de facto standard for modern language models owing to its parallelizable training and effective autoregressive decoding. However, its fixed context window and the quadratic time and memory costs of its self-attention mechanism remain central bottlenecks. These constraints have revived interest in recurrent architectures that scale linearly with sequence length, but at the cost of reduced parallelism. In this paper, we introduce Avey, a new foundational architecture that breaks away from both attention and recurrence. Avey pairs a ranker with an autoregressive neural processor to select and contextualize only the most relevant tokens for any given token. Specifically, it decouples sequence length from context width, thus enabling effective and efficient processing of arbitrarily long sequences. Results show that Avey compares favorably to the Transformer across a variety of standard short-range NLP benchmarks, while significantly outperforming it on tasks requiring long-range dependency modeling.
3D-Aware Vision-Language Models Fine-Tuning with Geometric Distillation
Lee, Seonho, Choi, Jiho, Kang, Inha, Kim, Jiwook, Park, Junsung, Shim, Hyunjung
Vision-Language Models (VLMs) have shown remarkable performance on diverse visual and linguistic tasks, yet they remain fundamentally limited in their understanding of 3D spatial structures. We propose Geometric Distillation, a lightweight, annotation-free fine-tuning framework that injects human-inspired geometric cues into pretrained VLMs without modifying their architecture. By distilling (1) sparse correspondences, (2) relative depth relations, and (3) dense cost volumes from off-the-shelf 3D foundation models (e.g., MASt3R, VGGT), our method shapes representations to be geometry-aware while remaining compatible with natural image-text inputs. Through extensive evaluations on 3D vision-language reasoning and 3D perception benchmarks, our method consistently outperforms prior approaches, achieving improved 3D spatial reasoning with significantly lower computational cost. Our work demonstrates a scalable and efficient path to bridge 2D-trained VLMs with 3D understanding, opening up wider use in spatially grounded multimodal tasks.
MetaTT: A Global Tensor-Train Adapter for Parameter-Efficient Fine-Tuning
Lopez-Piqueres, Javier, Deshpande, Pranav, Ray, Archan, Villani, Mattia J., Pistoia, Marco, Kumar, Niraj
We present MetaTT, a Tensor Train (TT) adapter framework for fine-tuning of pre-trained transformers. MetaTT enables flexible and parameter-efficient model adaptation by using a single shared TT to factorize transformer sub-modules. This factorization indexes key structural dimensions, including layer and matrix type, and can optionally incorporate heads and tasks. This design allows MetaTT's parameter count to scale with the sum, rather than the product, of the modes, resulting in a substantially more compact adapter. Our benchmarks compare MetaTT with LoRA along with recent state-of-the-art matrix and tensor decomposition based fine-tuning methods. We observe that when tested on single-task standard language modeling benchmarks, MetaTT achieves competitive parameter efficiency to accuracy tradeoff. We further demonstrate that MetaTT performs competitively when compared to state-of-the-art methods on multi-task learning. Finally, we leverage the TT-ansatz to design a rank adaptive optimizer inspired by the DMRG method from many-body physics. Our results demonstrate that integrating this approach with AdamW enhances optimization performance for a specified target rank.