The combination of modern Reinforcement Learning and Deep Learning approaches holds the promise of making significant progress on challenging applications requiring both rich perception and policy-selection. The Arcade Learning Environment (ALE) provides a set of Atari games that represent a useful benchmark set of such applications. A recent breakthrough in combining model-free reinforcement learning with deep learning, called DQN, achieves the best realtime agents thus far. Planning-based approaches achieve far higher scores than the best model-free approaches, but they exploit information that is not available to human players, and they are orders of magnitude slower than needed for real-time play. Our main goal in this work is to build a better real-time Atari game playing agent than DQN. The central idea is to use the slow planning-based agents to provide training data for a deep-learning architecture capable of real-time play. We proposed new agents based on this idea and show that they outperform DQN.

We consider the problem of inferring direct neural network connections from Calcium imaging time series. Inverse covariance estimation has proven to be a fast and accurate method for learning macro-and micro-scale network connectivity in the brain and in a recent Kaggle Connectomics competition inverse covariance was the main component of several top ten solutions, including our own and the winning team's algorithm. However, the accuracy of inverse covariance estimation is highly sensitive to signal preprocessing of the Calcium fluorescence time series. Furthermore, brute force optimization methods such as grid search and coordinate ascent over signal processing parameters is a time intensive process, where learning may take several days and parameters that optimize one network may not generalize to networks with different size and parameters. In this paper we show how inverse covariance estimation can be dramatically improved using a simple convolution filter prior to applying sample covariance. Furthermore, these signal processing parameters can be learned quickly using a supervised optimization algorithm. In particular, we maximize a binomial log-likelihood loss function with respect to a convolution filter of the time series and the inverse covariance regularization parameter. Our proposed algorithm is relatively fast on networks the size of those in the competition (1000 neurons), producing AUC scores with similar accuracy to the winning solution in training time under 2 hours on a cpu. Prediction on new networks of the same size is carried out in less than 15 minutes, the time it takes to read in the data and write out the solution.

Variational inference algorithms have proven successful for Bayesian analysis in large data settings, with recent advances using stochastic variational inference (SVI). However, such methods have largely been studied in independent or exchangeable data settings. We develop an SVI algorithm to learn the parameters of hidden Markov models (HMMs) in a time-dependent data setting. The challenge in applying stochastic optimization in this setting arises from dependencies in the chain, which must be broken to consider minibatches of observations. We propose an algorithm that harnesses the memory decay of the chain to adaptively bound errors arising from edge effects. We demonstrate the effectiveness of our algorithm on synthetic experiments and a large genomics dataset where a batch algorithm is computationally infeasible.

The success of machine learning, particularly in supervised settings, has led to numerous attempts to apply it in adversarial settings such as spam and malware detection. The core challenge in this class of applications is that adversaries are not static data generators, but make a deliberate effort to evade the classifiers deployed to detect them. We investigate both the problem of modeling the objectives of such adversaries, as well as the algorithmic problem of accounting for rational, objective-driven adversaries. In particular, we demonstrate severe shortcomings of feature reduction in adversarial settings using several natural adversarial objective functions, an observation that is particularly pronounced when the adversary is able to substitute across similar features (for example, replace words with synonyms or replace letters in words). We offer a simple heuristic method for making learning more robust to feature cross-substitution attacks. We then present a more general approach based on mixed-integer linear programming with constraint generation, which implicitly trades off overfitting and feature selection in an adversarial setting using a sparse regularizer along with an evasion model. Our approach is the first method for combining an adversarial classification algorithm with a very general class of models of adversarial classifier evasion. We show that our algorithmic approach significantly outperforms state-of-the-art alternatives.

The Indian Buffet Process is a versatile statistical tool for modeling distributions over binary matrices. We provide an efficient spectral algorithm as an alternative to costly Variational Bayes and sampling-based algorithms. We derive a novel tensorial characterization of the moments of the Indian Buffet Process proper and for two of its applications. We give a computationally efficient iterative inference algorithm, concentration of measure bounds, and reconstruction guarantees. Our algorithm provides superior accuracy and cheaper computation than comparable Variational Bayesian approach on a number of reference problems.

While there are many studies on weight regularization, the study on structure regularization is rare. Many existing systems on structured prediction focus on increasing the level of structural dependencies within the model. However, this trend could have been misdirected, because our study suggests that complex structures are actually harmful to generalization ability in structured prediction. To control structure-based overfitting, we propose a structure regularization framework via structure decomposition, which decomposes training samples into mini-samples with simpler structures, deriving a model with better generalization power. We show both theoretically and empirically that structure regularization can effectively control overfitting risk and lead to better accuracy. As a by-product, the proposed method can also substantially accelerate the training speed. The method and the theoretical results can apply to general graphical models with arbitrary structures. Experiments on well-known tasks demonstrate that our method can easily beat the benchmark systems on those highly-competitive tasks, achieving record-breaking accuracies yet with substantially faster training speed.

We present an algorithm for finding a chordal Markov network that maximizes any given decomposable scoring function.

Deep learning has been successfully applied to multimodal representation learning problems, with a common strategy to learning joint representations that are shared across multiple modalities on top of layers of modality-specific networks. Nonetheless, there still remains a question how to learn a good association between data modalities; in particular, a good generative model of multimodal data should be able to reason about missing data modality given the rest of data modalities. In this paper, we propose a novel multimodal representation learning framework that explicitly aims this goal. Rather than learning with maximum likelihood, we train the model to minimize the variation of information. We provide a theoretical insight why the proposed learning objective is sufficient to estimate the data-generating joint distribution of multimodal data. We apply our method to restricted Boltzmann machines and introduce learning methods based on contrastive divergence and multi-prediction training. In addition, we extend to deep networks with recurrent encoding structure to finetune the whole network. In experiments, we demonstrate the state-of-the-art visual recognition performance on MIR-Flickr database and PASCAL VOC 2007 database with and without text features.

We develop a scoring and classification procedure based on the PAC-Bayesian approach and the AUC (Area Under Curve) criterion. We focus initially on the class of linear score functions. We derive PAC-Bayesian non-asymptotic bounds for two types of prior for the score parameters: a Gaussian prior, and a spike-and-slab prior; the latter makes it possible to perform feature selection. One important advantage of our approach is that it is amenable to powerful Bayesian computational tools. We derive in particular a Sequential Monte Carlo algorithm, as an efficient method which may be used as a gold standard, and an Expectation-Propagation algorithm, as a much faster but approximate method. We also extend our method to a class of non-linear score functions, essentially leading to a nonparametric procedure, by considering a Gaussian process prior.

The Dawid-Skene estimator has been widely used for inferring the true labels from the noisy labels provided by non-expert crowdsourcing workers. However, since the estimator maximizes a non-convex log-likelihood function, it is hard to theoretically justify its performance. In this paper, we propose a two-stage efficient algorithm for multi-class crowd labeling problems. The first stage uses the spectral method to obtain an initial estimate of parameters.