Eye movements can reveal early signs of neurodegeneration, including those associated with Parkinson's Disease (PD). This work investigates the utility of a set of gaze-based features for the automatic screening of PD from different visual exploration tasks. For this purpose, a novel methodology is introduced, combining classic fixation/saccade oculomotor features (e.g., saccade count, fixation duration, scanned area) with features derived from gaze clusters (i.e., regions with a considerable accumulation of fixations). These features are automatically extracted from six exploration tests and evaluated using different machine learning classifiers. A Mixture of Experts ensemble is used to integrate outputs across tests and both eyes. Results show that ensemble models outperform individual classifiers, achieving an Area Under the Receiving Operating Characteristic Curve (AUC) of 0.95 on a held-out test set. The findings support visual exploration as a non-invasive tool for early automatic screening of PD.

In meta-learning and its downstream tasks, many methods rely on implicit adaptation to task variations, where multiple factors are mixed together in a single entangled representation. This makes it difficult to interpret which factors drive performance and can hinder generalization. In this work, we introduce a disentangled multi-context meta-learning framework that explicitly assigns each task factor to a distinct context vector. By decoupling these variations, our approach improves robustness through deeper task understanding and enhances generalization by enabling context vector sharing across tasks with shared factors. We evaluate our approach in two domains. First, on a sinusoidal regression task, our model outperforms baselines on out-of-distribution tasks and generalizes to unseen sine functions by sharing context vectors associated with shared amplitudes or phase shifts. Second, in a quadruped robot locomotion task, we disentangle the robot-specific properties and the characteristics of the terrain in the robot dynamics model. By transferring disentangled context vectors acquired from the dynamics model into reinforcement learning, the resulting policy achieves improved robustness under out-of-distribution conditions, surpassing the baselines that rely on a single unified context. Furthermore, by effectively sharing context, our model enables successful sim-to-real policy transfer to challenging terrains with out-of-distribution robot-specific properties, using just 20 seconds of real data from flat terrain, a result not achievable with single-task adaptation.

The demand for text classification is growing significantly in web searching, data mining, web ranking, recommendation systems, and so many other fields of information and technology. This paper illustrates the text classification process on different datasets using some standard supervised machine learning techniques. Text documents can be classified through various kinds of classifiers. Labeled text documents are used to classify the text in supervised classifications. This paper applies these classifiers on different kinds of labeled documents and measures the accuracy of the classifiers. An Artificial Neural Network (ANN) model using Back Propagation Network (BPN) is used with several other models to create an independent platform for labeled and supervised text classification process. An existing benchmark approach is used to analyze the performance of classification using labeled documents. Experimental analysis on real data reveals which model works well in terms of classification accuracy.

The making of knowledge engines in natural language processing has been shaped by two seemingly distinct paradigms: one grounded in structure, the other driven by massively available unstructured data. The structured paradigm leverages predefined symbolic interactions, such as knowledge graphs, as priors and designs models to capture them. In contrast, the unstructured paradigm centers on scaling transformer architectures with increasingly vast data and model sizes, as seen in modern large language models. Despite their divergence, this thesis seeks to establish conceptual connections bridging these paradigms. Two complementary forces, structure and destructure, emerge across both paradigms: structure organizes seen symbolic interactions, while destructure, through periodic embedding resets, improves model plasticity and generalization to unseen scenarios. These connections form a new recipe for developing general knowledge engines that can support transparent, controllable, and adaptable intelligent systems.

Humans intuitively navigate social interactions by simulating unspoken dynamics and reasoning about others' perspectives, even with limited information. In contrast, AI systems struggle to automatically structure and reason about these implicit social contexts. In this paper, we introduce a novel structured social world representation formalism (S3AP), designed to help AI systems reason more effectively about social dynamics. Following a POMDP-driven design, S3AP represents social interactions as structured tuples, such as state, observation, agent actions, and mental states, which can be automatically induced from free-form narratives or other inputs. We first show S3AP can help LLMs better understand social narratives across 5 social reasoning tasks (e.g., +51% improvement on FANToM's theory-of-mind reasoning with OpenAI's o1), reaching new state-of-the-art (SOTA) performance. We then induce social world models from these structured representations, demonstrating their ability to predict future social dynamics and improve agent decision-making, yielding up to +18% improvement on the SOTOPIA social interaction benchmark. Our findings highlight the promise of S3AP as a powerful, general-purpose representation for social world states, enabling the development of more socially-aware systems that better navigate social interactions.

Partially observable restless multi-armed bandits have found numerous applications including in recommendation systems, communication systems, public healthcare outreach systems, and in operations research. We study multi-action partially observable restless multi-armed bandits, it is a generalization of the classical restless multi-armed bandit problem -- 1) each bandit has finite states, and the current state is not observable, 2) each bandit has finite actions. In particular, we assume that more than two actions are available for each bandit. We motivate our problem with the application of public-health intervention planning. We describe the model and formulate a long term discounted optimization problem, where the state of each bandit evolves according to a Markov process, and this evolution is action dependent. The state of a bandit is not observable but one of finitely many feedback signals are observable. Each bandit yields a reward, based on the action taken on that bandit. The agent is assumed to have a budget constraint. The bandits are assumed to be independent. However, they are weakly coupled at the agent through the budget constraint. We first analyze the Lagrangian bound method for our partially observable restless bandits. The computation of optimal value functions for finite-state, finite-action POMDPs is non-trivial. Hence, the computation of Lagrangian bounds is also challenging. We describe approximations for the computation of Lagrangian bounds using point based value iteration (PBVI) and online rollout policy. We further present various properties of the value functions and provide theoretical insights on PBVI and online rollout policy. We study heuristic policies for multi-actions PORMAB. Finally, we discuss present Whittle index policies and their limitations in our model.

Traditional budget allocation models struggle with the stochastic and nonlinear nature of real-world financial data. This study proposes a hybrid reinforcement learning (RL) framework for dynamic budget allocation, enhanced with Dirichlet-inspired stochasticity and quantum mutation-based genetic optimization. Using Apple Inc. quarterly financial data (2009 to 2025), the RL agent learns to allocate budgets between Research and Development and Selling, General and Administrative to maximize profitability while adhering to historical spending patterns, with L2 penalties discouraging unrealistic deviations. A Dirichlet distribution governs state evolution to simulate shifting financial contexts. To escape local minima and improve generalization, the trained policy is refined using genetic algorithms with quantum mutation via parameterized qubit rotation circuits. Generation-wise rewards and penalties are logged to visualize convergence and policy behavior. On unseen fiscal data, the model achieves high alignment with actual allocations (cosine similarity 0.9990, KL divergence 0.0023), demonstrating the promise of combining deep RL, stochastic modeling, and quantum-inspired heuristics for adaptive enterprise budgeting.

Recent technological advances have expanded the availability of high-throughput biological datasets, enabling the reliable design of digital twins of biomedical systems or patients. Such computational tools represent key reaction networks driving perturbation or drug response and can guide drug discovery and personalized therapeutics. Yet, their development still relies on laborious data integration by the human modeler, so that automated approaches are critically needed. The success of data-driven system discovery in Physics, rooted in clean datasets and well-defined governing laws, has fueled interest in applying similar techniques in Biology, which presents unique challenges. Here, we reviewed methodologies for automatically inferring digital twins from biological time series, which mostly involve symbolic or sparse regression. We evaluate algorithms according to eight biological and methodological challenges, associated to noisy/incomplete data, multiple conditions, prior knowledge integration, latent variables, high dimensionality, unobserved variable derivatives, candidate library design, and uncertainty quantification. Upon these criteria, sparse regression generally outperformed symbolic regression, particularly when using Bayesian frameworks. We further highlight the emerging role of deep learning and large language models, which enable innovative prior knowledge integration, though the reliability and consistency of such approaches must be improved. While no single method addresses all challenges, we argue that progress in learning digital twins will come from hybrid and modular frameworks combining chemical reaction network-based mechanistic grounding, Bayesian uncertainty quantification, and the generative and knowledge integration capacities of deep learning. To support their development, we further propose a benchmarking framework to evaluate methods across all challenges.

Recent advances in reasoning and planning capabilities of large language models (LLMs) have enabled their potential as autonomous agents capable of tool use in dynamic environments. However, in multi-turn conversational environments like $τ$-bench, these agents often struggle with consistent reasoning, adherence to domain-specific policies, and extracting correct information over a long horizon of tool-calls and conversation. To capture and mitigate these failures, we conduct a comprehensive manual analysis of the common errors occurring in the conversation trajectories. We then experiment with reformulations of inputs to the tool-calling agent for improvement in agent decision making. Finally, we propose the Input-Reformulation Multi-Agent (IRMA) framework, which automatically reformulates user queries augmented with relevant domain rules and tool suggestions for the tool-calling agent to focus on. The results show that IRMA significantly outperforms ReAct, Function Calling, and Self-Reflection by 16.1%, 12.7%, and 19.1%, respectively, in overall pass^5 scores. These findings highlight the superior reliability and consistency of IRMA compared to other methods in dynamic environments.

Multimodal large language models (MLLMs) have emerged as pivotal tools in enhancing human-computer interaction. In this paper we focus on the application of MLLMs in the field of graphical user interface (GUI) elements structuring, where they assist in processing user instructions based on screen contents. Despite the promise of MLLMs, their performance in precisely generating UI element coordinates, a critical aspect of GUI understanding, is hindered by the nature of next-token prediction training. This challenge arises from the semantic void surrounding numerical UI coordinates in language representation spaces, necessitating a substantial and diverse dataset to bolster visual module capabilities. T o address these limitations, we introduce an IoU-Augmented Maximum Likelihood (IAML) training paradigm. Specifically, our approach involves a novel pipeline for IoU-based coordinate sampling to augment the training data, which considers the proximity to ground truth coordinates. This data augmentation strategy is then employed to fine-tune MLLMs under the IAML paradigm, which is designed to mitigate the exposure bias problem inherent in traditional maximum likelihood estimation. Through extensive experiments, we demonstrate the superior performance of our IAML training approach over traditional training paradigms.