We propose a mixed integer programming (MIP) model and iterative algorithms based on topological orders to solve optimization problems with acyclic constraints on a directed graph. The proposed MIP model has a significantly lower number of constraints compared to popular MIP models based on cycle elimination constraints and triangular inequalities. The proposed iterative algorithms use gradient descent and iterative reordering approaches, respectively, for searching topological orders. A computational experiment is presented for the Gaussian Bayesian network learning problem, an optimization problem minimizing the sum of squared errors of regression models with L1 penalty over a feature network with application of gene network inference in bioinformatics.

This course is about the fundamental concepts of machine learning, focusing on neural networks, SVM and decision trees. These topics are getting very hot nowadays because these learning algorithms can be used in several fields from software engineering to investment banking. Learning algorithms can recognize patterns which can help detect cancer for example or we may construct algorithms that can have a very very good guess about stock prices movement in the market. In each section we will talk about the theoretical background for all of these algorithms then we are going to implement these problems together. The first chapter is about regression: very easy yet very powerful and widely used machine learning technique.

In recent years, we've seen a resurgence in AI, or artificial intelligence, and machine learning. Machine learning has led to some amazing results, like being able to analyze medical images and predict diseases on-par with human experts. Google's AlphaGo program was able to beat a world champion in the strategy game go using deep reinforcement learning. Machine learning is even being used to program self driving cars, which is going to change the automotive industry forever. Imagine a world with drastically reduced car accidents, simply by removing the element of human error.

The Hidden Markov Model or HMM is all about learning sequences. A lot of the data that would be very useful for us to model is in sequences. Stock prices are sequences of prices. Language is a sequence of words. Credit scoring involves sequences of borrowing and repaying money, and we can use those sequences to predict whether or not you're going to default.

Abstract argumentation offers an appealing way of representing and evaluating arguments and counterarguments. This approach can be enhanced by considering probability assignments on arguments, allowing for a quantitative treatment of formal argumentation. In this paper, we regard the assignment as denoting the degree of belief that an agent has in an argument being acceptable. While there are various interpretations of this, an example is how it could be applied to a deductive argument. Here, the degree of belief that an agent has in an argument being acceptable is a combination of the degree to which it believes the premises, the claim, and the derivation of the claim from the premises. We consider constraints on these probability assignments, inspired by crisp notions from classical abstract argumentation frameworks and discuss the issue of probabilistic reasoning with abstract argumentation frameworks. Moreover, we consider the scenario when assessments on the probabilities of a subset of the arguments are given and the probabilities of the remaining arguments have to be derived, taking both the topology of the argumentation framework and principles of probabilistic reasoning into account. We generalise this scenario by also considering inconsistent assessments, i.e., assessments that contradict the topology of the argumentation framework. Building on approaches to inconsistency measurement, we present a general framework to measure the amount of conflict of these assessments and provide a method for inconsistency-tolerant reasoning.

I attended the Huawei European Innovation Day recently, and was enthralled by how the new technology is giving rise to industrial revolutions. These revolutions are what will eventually unlock the development potential around the world. It is important to leverage the emerging technologies, since they are the resources which will lead us to innovation and progress. Huawei is innovative in its partnerships and collaboration to define the future, and the event was a huge success. For many people, the concept of Artificial Intelligence (AI) is a thing of the future. It is the technology that has yet to be introduced.

The analysis of mixed data has been raising challenges in statistics and machine learning. One of two most prominent challenges is to develop new statistical techniques and methodologies to effectively handle mixed data by making the data less heterogeneous with minimum loss of information. The other challenge is that such methods must be able to apply in large-scale tasks when dealing with huge amount of mixed data. To tackle these challenges, we introduce parameter sharing and balancing extensions to our recent model, the mixed-variate restricted Boltzmann machine (MV.RBM) which can transform heterogeneous data into homogeneous representation. We also integrate structured sparsity and distance metric learning into RBM-based models. Our proposed methods are applied in various applications including latent patient profile modelling in medical data analysis and representation learning for image retrieval. The experimental results demonstrate the models perform better than baseline methods in medical data and outperform state-of-the-art rivals in image dataset.

Under Markovian assumptions, we leverage a Central Limit Theorem (CLT) for the empirical measure in the test statistic of the composite hypothesis Hoeffding test so as to establish weak convergence results for the test statistic, and, thereby, derive a new estimator for the threshold needed by the test. We first show the advantages of our estimator over an existing estimator by conducting extensive numerical experiments. We find that our estimator controls better for false alarms while maintaining satisfactory detection probabilities. We then apply the Hoeffding test with our threshold estimator to detecting anomalies in two distinct applications domains: one in communication networks and the other in transportation networks. The former application seeks to enhance cyber security and the latter aims at building smarter transportation systems in cities.

About this course: In previous courses in the Specialization, we have discussed how to sequence and compare genomes. This course will cover advanced topics in finding mutations lurking within DNA and proteins. In the first half of the course, we would like to ask how an individual's genome differs from the "reference genome" of the species. Our goal is to take small fragments of DNA from the individual and "map" them to the reference genome. We will see that the combinatorial pattern matching algorithms solving this problem are elegant and extremely efficient, requiring a surprisingly small amount of runtime and memory.

Natural language processing (NLP) has recently gained much attention for representing and analysing human language computationally. It has spread its applications in various fields such as machine translation, email spam detection, information extraction, summarization, medical, and question answering etc. The paper distinguishes four phases by discussing different levels of NLP and components of Natural Language Generation (NLG) followed by presenting the history and evolution of NLP, state of the art presenting the various applications of NLP and current trends and challenges.