We consider the problem of online planning in a Markov decision process with discounted rewards for any given initial state. We consider the PAC sample complexity problem of computing, with probability $1-\delta$, an $\epsilon$-optimal action using the smallest possible number of calls to the generative model (which provides reward and next-state samples). We design an algorithm, called StOP (for Stochastic-Optimistic Planning), based on the optimism in the face of uncertainty" principle. StOP can be used in the general setting, requires only a generative model, and enjoys a complexity bound that only depends on the local structure of the MDP." Papers published at the Neural Information Processing Systems Conference.

We show that the usual score function for conditional Markov networks can be written as the expectation over the scores of their spanning trees. We also show that a small random sample of these output trees can attain a significant fraction of the margin obtained by the complete graph and we provide conditions under which we can perform tractable inference. The experimental results confirm that practical learning is scalable to realistic datasets using this approach. Papers published at the Neural Information Processing Systems Conference.

Restricted Boltzmann machines are undirected neural networks which have been shown tobe effective in many applications, including serving as initializations fortraining deep multi-layer neural networks. One of the main reasons for their success is theexistence of efficient and practical stochastic algorithms, such as contrastive divergence,for unsupervised training. We propose an alternative deterministic iterative procedure based on an improved mean field method from statistical physics known as the Thouless-Anderson-Palmer approach. We demonstrate that our algorithm provides performance equal to, and sometimes superior to, persistent contrastive divergence, while also providing a clear and easy to evaluate objective function. We believe that this strategycan be easily generalized to other models as well as to more accurate higher-order approximations, paving the way for systematic improvements in training Boltzmann machineswith hidden units.

Lifted inference algorithms for probabilistic first-order logic frameworks such as Markov logic networks (MLNs) have received significant attention in recent years. These algorithms use so called lifting rules to identify symmetries in the first-order representation and reduce the inference problem over a large probabilistic model to an inference problem over a much smaller model. In this paper, we present two new lifting rules, which enable fast MAP inference in a large class of MLNs. Our first rule uses the concept of single occurrence equivalence class of logical variables, which we define in the paper. The rule states that the MAP assignment over an MLN can be recovered from a much smaller MLN, in which each logical variable in each single occurrence equivalence class is replaced by a constant (i.e., an object in the domain of the variable).

We develop a latent variable model and an efficient spectral algorithm motivated by the recent emergence of very large data sets of chromatin marks from multiple human cell types. A natural model for chromatin data in one cell type is a Hidden Markov Model (HMM); we model the relationship between multiple cell types by connecting their hidden states by a fixed tree of known structure. The main challenge with learning parameters of such models is that iterative methods such as EM are very slow, while naive spectral methods result in time and space complexity exponential in the number of cell types. We exploit properties of the tree structure of the hidden states to provide spectral algorithms that are more computationally efficient for current biological datasets. We provide sample complexity bounds for our algorithm and evaluate it experimentally on biological data from nine human cell types.

The problem of estimating an unknown discrete distribution from its samples is a fundamental tenet of statistical learning. Over the past decade, it attracted significant research effort and has been solved for a variety of divergence measures. Surprisingly, an equally important problem, estimating an unknown Markov chain from its samples, is still far from understood. We consider two problems related to the min-max risk (expected loss) of estimating an unknown k-state Markov chain from its n sequential samples: predicting the conditional distribution of the next sample with respect to the KL-divergence, and estimating the transition matrix with respect to a natural loss induced by KL or a more general f-divergence measure. For the first measure, we determine the min-max prediction risk to within a linear factor in the alphabet size, showing it is \Omega(k\log\log n/n) and O(k 2\log\log n/n).

We extend the multinomial logit model to represent some of the empirical phenomena that are frequently observed in the choices made by humans. These phenomena include the similarity effect, the attraction effect, and the compromise effect. We formally quantify the strength of these phenomena that can be represented by our choice model, which illuminates the flexibility of our choice model. We then show that our choice model can be represented as a restricted Boltzmann machine and that its parameters can be learned effectively from data. Our numerical experiments with real data of human choices suggest that we can train our choice model in such a way that it represents the typical phenomena of choice.

At the working heart of policy iteration algorithms commonly used and studied in the discounted setting of reinforcement learning, the policy evaluation step estimates the value of state with samples from a Markov reward process induced by following a Markov policy in a Markov decision process. We propose a simple and efficient estimator called \emph{loop estimator} that exploits the regenerative structure of Markov reward processes without explicitly estimating a full model. Our method enjoys a space complexity of $O(1)$ when estimating the value of a single positive recurrent state $s$ unlike TD (with $O(S)$) or model-based methods (with $O(S^2)$). Moreover, the regenerative structure enables us to show, without relying on the generative model approach, that the estimator has an instance-dependent convergence rate of $\widetilde{O}(\sqrt{\tau_s/T})$ over steps $T$ on a single sample path, where $\tau_s$ is the maximal expected hitting time to state $s$. In preliminary numerical experiments, the loop estimator outperforms model-free methods, such as TD(k), and is competitive with the model-based estimator.

Patients whose transfer to the Intensive Care Unit (ICU) is unplanned are prone to higher mortality rates than those who were admitted directly to the ICU. Recent advances in machine learning to predict patient deterioration have introduced the possibility of \emph{proactive transfer} from the ward to the ICU. In this work, we study the problem of finding \emph{robust} patient transfer policies which account for uncertainty in statistical estimates due to data limitations when optimizing to improve overall patient care. We propose a Markov Decision Process model to capture the evolution of patient health, where the states represent a measure of patient severity. Under fairly general assumptions, we show that an optimal transfer policy has a threshold structure, i.e., that it transfers all patients above a certain severity level to the ICU (subject to available capacity). As model parameters are typically determined based on statistical estimations from real-world data, they are inherently subject to misspecification and estimation errors. We account for this parameter uncertainty by deriving a robust policy that optimizes the worst-case reward across all plausible values of the model parameters. We show that the robust policy also has a threshold structure under fairly general assumptions. Moreover, it is more aggressive in transferring patients than the optimal nominal policy, which does not take into account parameter uncertainty. We present computational experiments using a dataset of hospitalizations at 21 KNPC hospitals, and present empirical evidence of the sensitivity of various hospital metrics (mortality, length-of-stay, average ICU occupancy) to small changes in the parameters. Our work provides useful insights into the impact of parameter uncertainty on deriving simple policies for proactive ICU transfer that have strong empirical performance and theoretical guarantees.

State variables are easily the most subtle dimension of sequential decision problems. This is especially true in the context of active learning problems (bandit problems") where decisions affect what we observe and learn. We describe our canonical framework that models {\it any} sequential decision problem, and present our definition of state variables that allows us to claim: Any properly modeled sequential decision problem is Markovian. We then present a novel two-agent perspective of partially observable Markov decision problems (POMDPs) that allows us to then claim: Any model of a real decision problem is (possibly) non-Markovian. We illustrate these perspectives using the context of observing and treating flu in a population, and provide examples of all four classes of policies in this setting. We close with an indication of how to extend this thinking to multiagent problems.