Spike sorting involves Clustering spike trains recorded by a micro-electrode according to the source neuron.

In this paper we present a framework for using multi-layer perceptron (MLP)networks in nonlinear generative models trained by variational Bayesian learning. The nonlinearity is handled by linearizing it using a Gauss-Hermite quadrature at the hidden neurons. Thisyields an accurate approximation for cases of large posterior variance.The method can be used to derive nonlinear counterparts forlinear algorithms such as factor analysis, independent component/factor analysis and state-space models. This is demonstrated witha nonlinear factor analysis experiment in which even 20 sources can be estimated from a real world speech data set.

While clustering is usually an unsupervised operation, there are circumstances inwhich we believe (with varying degrees of certainty) that items A and B should be assigned to the same cluster, while items A and C should not. We would like such pairwise relations to influence cluster assignments of out-of-sample data in a manner consistent with the prior knowledge expressed in the training set. Our starting point is probabilistic clusteringbased on Gaussian mixture models (GMM) of the data distribution. We express clustering preferences in the prior distribution over assignments of data points to clusters. This prior penalizes cluster assignments according to the degree with which they violate the preferences.

This paper analyzes generalization of the Classic Rescorla-Wagner (R-W) learning algon'thm and studies their relationship to Maximum Likelihood estimation of causal parameters.

Inference in these "exponential family harrnoniums" is

We propose a "soft greedy" learning algorithm for building small conjunctions of simple threshold functions, called rays, defined on single real-valued attributes. We also propose a PAC-Bayes risk bound which is minimized for classifiers achieving a nontrivial tradeoff between sparsity (the number of rays used) and the magnitude ofthe separating margin of each ray. Finally, we test the soft greedy algorithm on four DNA micro-array data sets.

Statistical approaches to language learning typically focus on either short-range syntactic dependencies or long-range semantic dependencies between words. We present a generative model that uses both kinds of dependencies, and can be used to simultaneously find syntactic classes and semantic topics despite having no representation of syntax or semantics beyondstatistical dependency. This model is competitive on tasks like part-of-speech tagging and document classification with models that exclusively use short-and long-range dependencies respectively.

As animals interact with their environments, they must constantly update estimates about their states. Bayesian models combine prior probabilities, adynamical model and sensory evidence to update estimates optimally. Thesemodels are consistent with the results of many diverse psychophysical studies. However, little is known about the neural representation andmanipulation of such Bayesian information, particularly in populations of spiking neurons. We consider this issue, suggesting a model based on standard neural architecture and activations. We illustrate theapproach on a simple random walk example, and apply it to a sensorimotor integration task that provides a particularly compelling example of dynamic probabilistic computation. Bayesian models have been used to explain a gamut of experimental results in tasks which require estimates to be derived from multiple sensory cues.

We propose the hierarchical Dirichlet process (HDP), a nonparametric Bayesian model for clustering problems involving multiple groups of data. Each group of data is modeled with a mixture, with the number of components being open-ended and inferred automatically by the model. Further, components can be shared across groups, allowing dependencies across groups to be modeled effectively as well as conferring generalization tonew groups. Such grouped clustering problems occur often in practice, e.g. in the problem of topic discovery in document corpora. We report experimental results on three text corpora showing the effective and superior performance of the HDP over previous models.

We explicitly treat two cases.