Heart failure is a life-threatening condition that affects millions of people worldwide. The ability to accurately predict patient survival can aid in early intervention and improve patient outcomes. In this study, we explore the potential of utilizing data pre-processing techniques and the Extra-Tree (ET) feature selection method in conjunction with the Random Forest (RF) classifier to improve survival prediction in heart failure patients. By leveraging the strengths of ET feature selection, we aim to identify the most significant predictors associated with heart failure survival. Using the public UCL Heart failure (HF) survival dataset, we employ the ET feature selection algorithm to identify the most informative features. These features are then used as input for grid search of RF. Finally, the tuned RF Model was trained and evaluated using different matrices. The approach was achieved 98.33% accuracy that is the highest over the exiting work.

Causal random forests provide efficient estimates of heterogeneous treatment effects. However, forest algorithms are also well-known for their black-box nature, and therefore, do not characterize how input variables are involved in treatment effect heterogeneity, which is a strong practical limitation. In this article, we develop a new importance variable algorithm for causal forests, to quantify the impact of each input on the heterogeneity of treatment effects. The proposed approach is inspired from the drop and relearn principle, widely used for regression problems. Importantly, we show how to handle the forest retrain without a confounding variable. If the confounder is not involved in the treatment effect heterogeneity, the local centering step enforces consistency of the importance measure. Otherwise, when a confounder also impacts heterogeneity, we introduce a corrective term in the retrained causal forest to recover consistency. Additionally, experiments on simulated, semi-synthetic, and real data show the good performance of our importance measure, which outperforms competitors on several test cases. Experiments also show that our approach can be efficiently extended to groups of variables, providing key insights in practice.

Tabular data represents one of the most prevalent form of data. When it comes to data generation, many approaches would learn a density for the data generation process, but would not necessarily end up with a sampler, even less so being exact with respect to the underlying density. A second issue is on models: while complex modeling based on neural nets thrives in image or text generation (etc.), less is known for powerful generative models on tabular data. A third problem is the visible chasm on tabular data between training algorithms for supervised learning with remarkable properties (e.g. boosting), and a comparative lack of guarantees when it comes to data generation. In this paper, we tackle the three problems, introducing new tree-based generative models convenient for density modeling and tabular data generation that improve on modeling capabilities of recent proposals, and a training algorithm which simplifies the training setting of previous approaches and displays boosting-compliant convergence. This algorithm has the convenient property to rely on a supervised training scheme that can be implemented by a few tweaks to the most popular induction scheme for decision tree induction with two classes. Experiments are provided on missing data imputation and comparing generated data to real data, displaying the quality of the results obtained by our approach, in particular against state of the art.

Privacy enhancing technologies (PETs) have been proposed as a way to protect the privacy of data while still allowing for data analysis. In this work, we focus on Fully Homomorphic Encryption (FHE), a powerful tool that allows for arbitrary computations to be performed on encrypted data. FHE has received lots of attention in the past few years and has reached realistic execution times and correctness. More precisely, we explain in this paper how we apply FHE to tree-based models and get state-of-the-art solutions over encrypted tabular data. We show that our method is applicable to a wide range of tree-based models, including decision trees, random forests, and gradient boosted trees, and has been implemented within the Concrete-ML library, which is open-source at https://github.com/zama-ai/concrete-ml. With a selected set of use-cases, we demonstrate that our FHE version is very close to the unprotected version in terms of accuracy.

Epilepsy is a prevalent neurological disorder characterized by recurrent and unpredictable seizures, necessitating accurate prediction for effective management and patient care. Application of machine learning (ML) on electroencephalogram (EEG) recordings, along with its ability to provide valuable insights into brain activity during seizures, is able to make accurate and robust seizure prediction an indispensable component in relevant studies. In this research, we present a comprehensive comparative analysis of five machine learning models - Random Forest (RF), Decision Tree (DT), Extra Trees (ET), Logistic Regression (LR), and Gradient Boosting (GB) - for the prediction of epileptic seizures using EEG data. The dataset underwent meticulous preprocessing, including cleaning, normalization, outlier handling, and oversampling, ensuring data quality and facilitating accurate model training. These preprocessing techniques played a crucial role in enhancing the models' performance. The results of our analysis demonstrate the performance of each model in terms of accuracy. The LR classifier achieved an accuracy of 56.95%, while GB and DT both attained 97.17% accuracy. RT achieved a higher accuracy of 98.99%, while the ET model exhibited the best performance with an accuracy of 99.29%. Our findings reveal that the ET model outperformed not only the other models in the comparative analysis but also surpassed the state-of-the-art results from previous research. The superior performance of the ET model makes it a compelling choice for accurate and robust epileptic seizure prediction using EEG data.

This paper proposes a machine learning-based approach for detecting the exploitation of vulnerabilities in the wild by monitoring underground hacking forums. The increasing volume of posts discussing exploitation in the wild calls for an automatic approach to process threads and posts that will eventually trigger alarms depending on their content. To illustrate the proposed system, we use the CrimeBB dataset, which contains data scraped from multiple underground forums, and develop a supervised machine learning model that can filter threads citing CVEs and label them as Proof-of-Concept, Weaponization, or Exploitation. Leveraging random forests, we indicate that accuracy, precision and recall above 0.99 are attainable for the classification task. Additionally, we provide insights into the difference in nature between weaponization and exploitation, e.g., interpreting the output of a decision tree, and analyze the profits and other aspects related to the hacking communities. Overall, our work sheds insight into the exploitation of vulnerabilities in the wild and can be used to provide additional ground truth to models such as EPSS and Expected Exploitability.

Autonomous mobile robots (AMR) operating in the real world often need to make critical decisions that directly impact their own safety and the safety of their surroundings. Learning-based approaches for decision making have gained popularity in recent years, since decisions can be made very quickly and with reasonable levels of accuracy for many applications. These approaches, however, typically return only one decision, and if the learner is poorly trained or observations are noisy, the decision may be incorrect. This problem is further exacerbated when the robot is making decisions about its own failures, such as faulty actuators or sensors and external disturbances, when a wrong decision can immediately cause damage to the robot. In this paper, we consider this very case study: a robot dealing with such failures must quickly assess uncertainties and make safe decisions. We propose an uncertainty aware learning-based failure detection and recovery approach, in which we leverage Decision Tree theory along with Model Predictive Control to detect and explain which failure is compromising the system, assess uncertainties associated with the failure, and lastly, find and validate corrective controls to recover the system. Our approach is validated with simulations and real experiments on a faulty unmanned ground vehicle (UGV) navigation case study, demonstrating recovery to safety under uncertainties.

Gene network information is believed to be beneficial for disease module and pathway identification, but has not been explicitly utilized in the standard random forest (RF) algorithm for gene expression data analysis. We investigate the performance of a network-guided RF where the network information is summarized into a sampling probability of predictor variables which is further used in the construction of the RF. Our results suggest that network-guided RF does not provide better disease prediction than the standard RF. In terms of disease gene discovery, if disease genes form module(s), network-guided RF identifies them more accurately. In addition, when disease status is independent from genes in the given network, spurious gene selection results can occur when using network information, especially on hub genes. Our empirical analysis on two balanced microarray and RNA-Seq breast cancer datasets from The Cancer Genome Atlas (TCGA) for classification of progesterone receptor (PR) status also demonstrates that network-guided RF can identify genes from PGR-related pathways, which leads to a better connected module of identified genes.

Machine learning (ML) is a promising approach for predicting small molecule properties in drug discovery. Here, we provide a comprehensive overview of various ML methods introduced for this purpose in recent years. We review a wide range of properties, including binding affinities, solubility, and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity). We discuss existing popular datasets and molecular descriptors and embeddings, such as chemical fingerprints and graph-based neural networks. We highlight also challenges of predicting and optimizing multiple properties during hit-to-lead and lead optimization stages of drug discovery and explore briefly possible multi-objective optimization techniques that can be used to balance diverse properties while optimizing lead candidates. Finally, techniques to provide an understanding of model predictions, especially for critical decision-making in drug discovery are assessed. Overall, this review provides insights into the landscape of ML models for small molecule property predictions in drug discovery. So far, there are multiple diverse approaches, but their performances are often comparable. Neural networks, while more flexible, do not always outperform simpler models. This shows that the availability of high-quality training data remains crucial for training accurate models and there is a need for standardized benchmarks, additional performance metrics, and best practices to enable richer comparisons between the different techniques and models that can shed a better light on the differences between the many techniques.

This paper explores the current trending research areas in the field of Computer Science (CS) and investigates the factors contributing to their emergence. Leveraging a comprehensive dataset comprising papers, citations, and funding information, we employ advanced machine learning techniques, including Decision Tree and Logistic Regression models, to predict trending research areas. Our analysis reveals that the number of references cited in research papers (Reference Count) plays a pivotal role in determining trending research areas making reference counts the most relevant factor that drives trend in the CS field. Additionally, the influence of NSF grants and patents on trending topics has increased over time. The Logistic Regression model outperforms the Decision Tree model in predicting trends, exhibiting higher accuracy, precision, recall, and F1 score. By surpassing a random guess baseline, our data-driven approach demonstrates higher accuracy and efficacy in identifying trending research areas. The results offer valuable insights into the trending research areas, providing researchers and institutions with a data-driven foundation for decision-making and future research direction.