Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles. The collected data cover 76% of all unique PubMed Medical Subject Headings descriptors. No systematic biases were observed across different experience levels, research fields or time spent on annotations.

Human emotions unfold over time, and more affective computing research has to prioritize capturing this crucial component of real-world affect. Modeling dynamic emotional stimuli requires solving the twin challenges of time-series modeling and of collecting high-quality time-series datasets. We begin by assessing the state-of-the-art in time-series emotion recognition, and we review contemporary time-series approaches in affective computing, including discriminative and generative models. We then introduce the first version of the Stanford Emotional Narratives Dataset (SENDv1): a set of rich, multimodal videos of self-paced, unscripted emotional narratives, annotated for emotional valence over time. The complex narratives and naturalistic expressions in this dataset provide a challenging test for contemporary time-series emotion recognition models. We demonstrate several baseline and state-of-the-art modeling approaches on the SEND, including a Long Short-Term Memory model and a multimodal Variational Recurrent Neural Network, which perform comparably to the human-benchmark. We end by discussing the implications for future research in time-series affective computing.

We built a bot that automatically reads doctors handwriting on Belgian death certificates with an accuracy of 47% of certificates of the usable data set correctly predicted. The bot supports government officials with the official death registration and allows for a faster such registration. The solution consists of three main components: an image-processing module, a neural net, and a natural-language processing module to output predictions of medical terms. When a person deceases, a medical practitioner must certify the deceased state of the person. There is a standard form which the physician fills in. This is done "in the field," through a handwritten statement on the form, which is subsequently forwarded to other officials under sealed envelope. The physician officially records the direct cause of death, and, if known, any secondary causes. An example of such a death certificate is given below. The example above is fairly straightforward to read, but notoriously difficult-to-read examples also exist. Because the physicians record death causes "in the field," a 100% digital solution is not feasible, and a lot of handwriting will exist for years to come. The raw data are one-page scans, provided as a PDF.

Certain research strands can yield "forbidden knowledge". This term refers to knowledge that is considered too sensitive, dangerous or taboo to be produced or shared. Discourses about such publication restrictions are already entrenched in scientific fields like IT security, synthetic biology or nuclear physics research. This paper makes the case for transferring this discourse to machine learning research. Some machine learning applications can very easily be misused and unfold harmful consequences, for instance with regard to generative video or text synthesis, personality analysis, behavior manipulation, software vulnerability detection and the like. Up to now, the machine learning research community embraces the idea of open access. However, this is opposed to precautionary efforts to prevent the malicious use of machine learning applications. Information about or from such applications may, if improperly disclosed, cause harm to people, organizations or whole societies. Hence, the goal of this work is to outline norms that can help to decide whether and when the dissemination of such information should be prevented. It proposes review parameters for the machine learning community to establish an ethical framework on how to deal with forbidden knowledge and dual-use applications.

Experimentation has become an increasingly prevalent tool for guiding policy choices, firm decisions, and product innovation. A common hurdle in designing experiments is the lack of statistical power. In this paper, we study optimal multi-period experimental design under the constraint that the treatment cannot be easily removed once implemented; for example, a government or firm might implement treatment in different geographies at different times, where the treatment cannot be easily removed due to practical constraints. The design problem is to select which units to treat at which time, intending to test hypotheses about the effect of the treatment. When the potential outcome is a linear function of a unit effect, a time effect, and observed discrete covariates, we provide an analytically feasible solution to the design problem where the variance of the estimator for the treatment effect is at most 1+O(1/N^2) times the variance of the optimal design, where N is the number of units. This solution assigns units in a staggered treatment adoption pattern, where the proportion treated is a linear function of time. In the general setting where outcomes depend on latent covariates, we show that historical data can be utilized in the optimal design. We propose a data-driven local search algorithm with the minimax decision criterion to assign units to treatment times. We demonstrate that our approach improves upon benchmark experimental designs through synthetic experiments on real-world data sets from several domains, including healthcare, finance, and retail. Finally, we consider the case where the treatment effect changes with the time of treatment, showing that the optimal design treats a smaller fraction of units at the beginning and a greater share at the end.

This is most apparent when auto-encoders are trained, where a network is trained to map the input data upon itself but is forced to project them into a lower-dimensional embedding space on the way (Vincent et al., 2010). In addition to the conventional fully connected layers, there are various special types of network connections. For example, in computer vision, convolu-tional layers are commonly used, which train multiple sliding windows that move over the image data and process just a part of the image at a time, thereby learning to recognize local features. These layers are subsequently abstracted into more and more complex visual patterns (Krizhevsky et al., 2017). For temporal data, one can use recurrent neural networks, which do not make predictions for individual input vectors, but for a sequence of input vectors. To do so, they allow feeding abstracted information from previous data points forward to the next layers.

Prec ision Medicine (PM) is an emerging approach that appears with the impression of changing the existing paradigm of medical practice. Recent advances in technological innovations and genetics, and the growing availability of health data have set a new pace o f the research and imposes a set of new requirements on different stakeholders. To date, some studies are available that discuss about different aspects of PM. Nevertheless, a holistic representation of those aspects deemed to confer the technological pers pective, in relation to applications and challenges, is mostly ignored. In this context, this paper surveys advances in PM from informatics viewpoint and reviews the enabling tools and techniques in a categorized manner. In addition, the study discusses ho w other technological paradigms including big data, artificial intelligence, and internet of things can be exploited to advance the potentials of PM. Furthermore, the paper provides some guidelines for future research for seamless implementation and wide - s cale deployment of PM based on identified open issues and associated challenges. To this end, the paper proposes an integrated holistic framework for PM motivating informatics researchers to design their relevant research works in an appropriate context.

North Carolina's public community colleges had a problem. Although the system had a wealth of learning resources faculty members could use to develop their courses, there was no simple way to share and organize those materials across all 58 campuses. That will soon change, however, with the help of artificial intelligence (AI). Through the machine learning company Tanjo, the community college system is rolling out a custom AI "brain" in the coming months that will map and organize its digital content. The new tool will be critical to linking faculty to relevant resources, said Richard Boyd, Tanjo's CEO. Rather than wade through thousands of files in disparate places, faculty members will be able to use the AI system to source documents of interest to them from a central location.

The importance of automated Facial Emotion Recognition (FER) grows the more common human-machine interactions become, which will only continue to increase dramatically with time. A common method to describe human sentiment or feeling is the categorical model the `7 basic emotions', consisting of `Angry', `Disgust', `Fear', `Happiness', `Sadness', `Surprise' and `Neutral'. The `Emotion Recognition in the Wild' (EmotiW) competition is now in its 7th year and has become the standard benchmark for measuring FER performance. The focus of this paper is the EmotiW sub-challenge of classifying videos in the `Acted Facial Expression in the Wild' (AFEW) dataset, consisting of both visual and audio modalities, into one of the above classes. Machine learning has exploded as a research topic in recent years, with advancements in `Deep Learning' a key part of this. Although Deep Learning techniques have been widely applied to the FER task by entrants in previous years, this paper has two main contributions: (i) to apply the latest `state-of-the-art' visual and temporal networks and (ii) exploring various methods of fusing features extracted from the visual and audio elements to enrich the information available to the final model making the prediction. There are a number of complex issues that arise when trying to classify emotions for `in-the-wild' video sequences, which the above two approaches attempt to directly address. There are some positive findings when comparing the results of this paper to past submissions, indicating that further research into the proposed methods and fine-tuning of the models deployed, could result in another step forwards in the field of automated FER.

In recent years, the interest in Big Data sources has been steadily growing within the Official Statistic community. The Italian National Institute of Statistics (Istat) is currently carrying out several Big Data pilot studies. One of these studies, the ICT Big Data pilot, aims at exploiting massive amounts of textual data automatically scraped from the websites of Italian enterprises in order to predict a set of target variables (e.g. e-commerce) that are routinely observed by the traditional ICT Survey. In this paper, we show that Deep Learning techniques can successfully address this problem. Essentially, we tackle a text classification task: an algorithm must learn to infer whether an Italian enterprise performs e-commerce from the textual content of its website. To reach this goal, we developed a sophisticated processing pipeline and evaluated its performance through extensive experiments. Our pipeline uses Convolutional Neural Networks and relies on Word Embeddings to encode raw texts into grayscale images (i.e. normalized numeric matrices). Web-scraped texts are huge and have very low signal to noise ratio: to overcome these issues, we adopted a framework known as False Positive Reduction, which has seldom (if ever) been applied before to text classification tasks. Several original contributions enable our processing pipeline to reach good classification results. Empirical evidence shows that our proposal outperforms all the alternative Machine Learning solutions already tested in Istat for the same task.