Industry
PANORAMA: ADataset and Benchmarks Capturing Decision Trails and Rationales in Patent Examination
Patent examination remains an ongoing challenge in the NLP literature even after the advent of large language models (LLMs), as it requires an extensive yet nuanced human judgment on whether a submitted claim meets the statutory standards of novelty and non-obviousness against previously granted claims--prior art--in expert domains. Previous NLP studies have approached this challenge as a prediction task (e.g., forecasting grant outcomes) with high-level proxies such as similarity metrics or classifiers trained on historical labels. However, this approach often overlooks the step-by-step evaluations that examiners must make with profound information, including rationales for the decisions provided in office actions documents, which also makes it harder to measure the current state of techniques in patent review processes. To fill this gap, we construct PANORAMA, a dataset of 8,143 U.S. patent examination records that preserves the full decision trails, including original applications, all cited references, Non-Final Rejections, and Notices of Allowance. Also, PANORAMA decomposes the trails into sequential benchmarks that emulate patent professionals' patent review processes and allow researchers to examine large language models' capabilities at each step of them. Our findings indicate that, although LLMs are relatively effective at retrieving relevant prior art and pinpointing the pertinent paragraphs, they struggle to assess the novelty and non-obviousness of patent claims. We discuss these results and argue that advancing NLP, including LLMs, in the patent domain requires a deeper understanding of real-world patent examination.
Grids Often Outperform Implicit Neural Representation at Compressing Dense Signals
Implicit Neural Representations (INRs) have recently shown impressive results, but their fundamental capacity, implicit biases, and scaling behavior remain poorly understood. We investigate the performance of diverse INRs across a suite of 2D and 3D real and synthetic signals with varying effective bandwidth, as well as both overfitting and generalization tasks including tomography, super-resolution, and denoising. By stratifying performance according to model size as well as signal type and bandwidth, our results shed light on how different INR and grid representations allocate their capacity. We find that, for most tasks and signals, a simple regularized grid with interpolation trains faster and to higher quality than any INR with the same number of parameters. We also find limited settings-namely fitting binary signals such as shape contours-where INRs outperform grids, to guide future development and use of INRs towards the most advantageous applications.
SimWorld-Robotics: Synthesizing Photorealistic and Dynamic Urban Environments for Multimodal Robot Navigation and Collaboration
Recent advances in foundation models have shown promising results in developing generalist robotics that can perform diverse tasks in open-ended scenarios given multimodal inputs. However, current work has been mainly focused on indoor, household scenarios. In this work, we present SimWorldRobotics (SWR), a simulation platform for embodied AI in large-scale, photorealistic urban environments. Built on Unreal Engine 5, SWR procedurally generates unlimited photorealistic urban scenes populated with dynamic elements such as pedestrians and traffic systems, surpassing prior urban simulations in realism, complexity, and scalability. It also supports multi-robot control and communication. With these key features, we build two challenging robot benchmarks: (1) a multimodal instruction-following task, where a robot must follow vision-language navigation instructions to reach a destination in the presence of pedestrians and traffic; and (2) a multi-agent search task, where two robots must communicate to cooperatively locate and meet each other. Unlike existing benchmarks, these two new benchmarks comprehensively evaluate a wide range of critical robot capacities in realistic scenarios, including (1) multimodal instructions grounding, (2) 3D spatial reasoning in large environments, (3) safe, long-range navigation with people and traffic, (4) multi-robot collaboration, and (5) grounded communication. Our experimental results demonstrate that stateof-the-art models, including vision-language models (VLMs), struggle with our tasks, lacking robust perception, reasoning, and planning abilities necessary for urban environments.
ConnectomeBench: Can LLMs Proofread the Connectome?
Connectomics--the mapping of neural connections in an organism's brain--currently requires extraordinary human effort to proofread the data collected from imaging and machine-learning assisted segmentation. With the growing excitement around using AI agents to automate important scientific tasks, we explore whether current AI systems can perform multiple tasks necessary for data proofreading. We introduce ConnectomeBench, a multimodal benchmark evaluating large language model (LLM) capabilities in three critical proofreading tasks: segment type identification, split error correction, and merge error detection. Using expert annotated data from two large open-source datasets--a cubic millimeter of mouse visual cortex and the complete Drosophila brain--we evaluate proprietary multimodal LLMs including Claude 3.7/4 Sonnet, o4-mini, GPT-4.1,
MuSLR: Multimodal Symbolic Logical Reasoning
Multimodal symbolic logical reasoning, which aims to deduce new facts from multimodal input via formal logic, is critical in high-stakes applications such as autonomous driving and medical diagnosis, as its rigorous, deterministic reasoning helps prevent serious consequences. To evaluate such capabilities of current state-of-the-art vision language models (VLMs), we introduce MuSLR, the first multimodal symbolic logical reasoning grounded in formal logical rules. We curate a benchmark dataset for MuSLR comprising 1,093 instances across 7 domains, including 35 atomic symbolic logic and 976 logical combinations, with reasoning depths ranging from 2 to 9. We evaluate 7 state-of-the-art VLMs on our benchmark and find that they all struggle with multimodal symbolic reasoning, with the best model, GPT-4.1, achieving only 46.8%. Thus, we propose LogiCAM, a modular framework that applies formal logical rules to multimodal inputs, boosting GPT-4.1's
Generalizable, real-time neural decoding with hybrid state-space models
Real-time decoding of neural activity is central to neuroscience and neurotechnology applications, from closed-loop experiments to brain-computer interfaces, where models are subject to strict latency constraints. Traditional methods, including simple recurrent neural networks, are fast and lightweight but often struggle to generalize to unseen data. In contrast, recent Transformer-based approaches leverage large-scale pretraining for strong generalization performance, but typically have much larger computational requirements and are not always suitable for lowresource or real-time settings. To address these shortcomings, we present POSSM, a novel hybrid architecture that combines individual spike tokenization via a crossattention module with a recurrent state-space model (SSM) backbone to enable (1) fast and causal online prediction on neural activity and (2) efficient generalization to new sessions, individuals, and tasks through multi-dataset pretraining. We evaluate POSSM's decoding performance and inference speed on intracortical decoding of monkey motor tasks, and show that it extends to clinical applications, namely handwriting and speech decoding in human subjects. Notably, we demonstrate that pretraining on monkey motor-cortical recordings improves decoding performance on the human handwriting task, highlighting the exciting potential for cross-species transfer. In all of these tasks, we find that POSSM achieves decoding accuracy comparable to state-of-the-art Transformers, at a fraction of the inference cost (up to 9 faster on GPU). These results suggest that hybrid SSMs are a promising approach to bridging the gap between accuracy, inference speed, and generalization when training neural decoders for real-time, closed-loop applications.
Balanced Active Inference
Limited labeling budget severely impedes data-driven research, such as medical analysis, remote sensing and population census, and active inference is a solution to this problem. Prior works utilizing independent sampling have achieved improvements over uniform sampling, but its insufficient usage of available information undermines its statistical efficiency. In this paper, we propose balanced active inference, a novel algorithm that incorporates balancing constraints based on model uncertainty utilizing the cube method for label selection. Under regularity conditions, we establish its asymptotic properties and also prove that the statistical efficiency of the proposed algorithm is higher than its alternatives. Various numerical experiments, including regression and classification in both synthetic setups and real data analysis, demonstrate that the proposed algorithm outperforms its alternatives while guaranteeing nominal coverage. Our code is available at: https://github.com/Uninfty/Balanced_Active_Inference
Bidirectional Representations Augmented Autoregressive Biological Sequence Generation
Autoregressive (AR) models, common in sequence generation, are limited in many biological tasks like de novo peptide sequencing and protein modeling by their unidirectional nature, failing to capture crucial global bidirectional token dependencies. Non-Autoregressive (NAR) models offer holistic, bidirectional representations but face challenges with generative coherence and scalability. To transcend this, we propose a hybrid framework enhancing AR generation by dynamically integrating rich contextual information from non-autoregressive mechanisms. Our approach couples a shared input encoder with two decoders: a non-autoregressive one learning latent bidirectional biological features, and an AR decoder synthesizing the biological sequence by leveraging these bi-directional features. A novel cross-decoder attention module enables the AR decoder to iteratively query and integrate these bidirectional features, enriching its predictions. This synergy is cultivated via a tailored training strategy with importance annealing for balanced objectives and cross-decoder gradient blocking for stable, focused learning.