Large language models (LLMs) have revolutionized natural language processing and are increasingly applied to other sequential data types, including genetic sequences. However, adapting LLMs to genetics presents significant challenges. Capturing complex genomic interactions requires modeling long-range global dependencies within DNA sequences, where interactions often span over 10,000 base pairs, even within a single gene. This poses substantial computational demands under conventional model architectures and training paradigms. Additionally, traditional LLM training approaches are suboptimal for DNA sequences: autoregressive training, while efficient for training, only supports unidirectional sequence understanding. However, DNA is inherently bidirectional.

TIL you can schedule prompts in ChatGPT. Did you know you could schedule tasks in ChatGPT? I'll be honest, I never thought to ask OpenAI's chatbot to do something in the future, and it seems like a lot of you didn't either, because the company has begun rolling out an update that better highlights ChatGPT's ability to do just that. The next time you open ChatGPT's sidebar, you'll see a shortcut to a new Scheduled page that gives you a place to see any active tasks you might have assigned to ChatGPT, including when they're set to run. From this page, you can also pause, edit and delete any upcoming requests.

Multimodal deep learning systems are deployed in dynamic scenarios due to the robustness afforded by multiple sensing modalities. Nevertheless, they struggle with varying compute resource availability (due to multi-tenancy, device heterogeneity, etc.) and fluctuating quality of inputs (from sensor feed corruption, environmental noise, etc.). Statically provisioned multimodal systems cannot adapt when compute resources change over time, while existing dynamic networks struggle with strict compute budgets.

Active statistical inference [51] is a new method for inference with AI-assisted data collection. Given a budget on the number of labeled data points that can be collected and assuming access to an AI predictive model, the basic idea is to improve estimation accuracy by prioritizing the collection of labels where the model is most uncertain. The drawback, however, is that inaccurate uncertainty estimates can make active sampling produce highly noisy results, potentially worse than those from naive uniform sampling.

Mobile agents rely on Large Language Models (LLMs) to plan and execute tasks on smartphone user interfaces (UIs). While cloud-based LLMs achieve high task accuracy, they require uploading the full UI state at every step, exposing unnecessary and often irrelevant information. In contrast, local LLMs avoid UI uploads but suffer from limited capacity, resulting in lower task success rates. We propose CORE, a COllaborative framework that combines the strengths of cloud and local LLMs to Reduce UIExposure, while maintaining task accuracy for mobile agents. CORE comprises three key components: (1) Layout-aware block partitioning, which groups semantically related UI elements based on the XML screen hierarchy; (2) Co-planning, where local and cloud LLMs collaboratively identify the current sub-task; and (3) Co-decision-making, where the local LLM ranks relevant UI blocks, and the cloud LLM selects specific UI elements within the top-ranked block. CORE further introduces a multi-round accumulation mechanism to mitigate local misjudgment or limited context. Experiments across diverse mobile apps and tasks show that CORE reduces UI exposure by up to 55.6% while maintaining task success rates slightly below cloud-only agents, effectively mitigating unnecessary privacy exposure to the cloud.2

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The open-source release of large language models (LLMs) enables malicious users to create unauthorized derivative models at low cost, posing significant threats to intellectual property (IP) and market stability. Existing IP protection methods either require access to model parameters or are vulnerable to fine-tuning attacks. To fill this gap, we propose ErrorTrace, a robust and black-box traceability mechanism for protecting LLMIP.

Searching over semi-structured data with natural language (NL) queries has attracted sustained attention, enabling broader audiences to access information easily. As more applications, such as LLM agents and RAG systems, emerge to search and interact with semi-structured data, two major challenges have become evident: (1) the increasing diversity of domains and schema variations, making domain-customized solutions prohibitively costly; (2) the growing complexity of NL queries, which combine both exact field matching conditions and fuzzy semantic requirements, often involving multiple fields and implicit reasoning. These challenges make formal language querying or keyword-based search insufficient. In this work, we explore neural retrievers as a unified non-formal querying solution by directly index semi-structured collections and understand NL queries. We employ LLM-based automatic evaluation and build a large-scale semi-structured retrieval benchmark (SSRB) using LLM generation and filtering, containing 14M semi-structured objects from 99 different schemas across 6 domains, along with 8,485 test queries that combine both exact and fuzzy matching conditions. Our systematic evaluation of popular retrievers shows that current state-of-the-art models could achieve acceptable performance, yet they still lack precise understanding of matching constraints. While by in-domain training of dense retrievers, the performance can be significantly improved. We believe that our SSRBcould serve as a valuable resource for future research in this area, and we hope to inspire further exploration of semi-structured retrieval with complex queries.

We propose a unified framework for adaptive routing in multitask, multimodal prediction settings where data heterogeneity and task interactions vary across samples. We introduce a routing-based architecture that dynamically selects modality processing pathways and task-sharing strategies on a per-sample basis. Our model defines multiple modality paths, including raw and fused representations of text and numeric features, and learns to route each input through the most informative modality-task expert combination. Task-specific predictions are produced by shared or independent heads depending on the routing decision, and the entire system is trained end-to-end. We evaluate the model on both synthetic data and real-world psychotherapy notes, predicting depression and anxiety outcomes. Our experiments show that our method consistently outperforms fixed multitask or single-task baselines, and that the learned routing policy provides interpretable insights into modality relevance and task structure. This addresses critical challenges in personalized healthcare by providing per-subject adaptive information processing that accounts for data and task correlation heterogeneity.

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