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Toward a Vision-Language Foundation Model for Medical Data: Multimodal Dataset and Benchmarks for Vietnamese PET/CT Report Generation
Vision-Language Foundation Models (VLMs), trained on large-scale multimodal datasets, have driven significant advances in Artificial Intelligence (AI) by enabling rich cross-modal reasoning. Despite their success in general domains, applying these models to medical imaging remains challenging due to the limited availability of diverse imaging modalities and multilingual clinical data. Most existing medical VLMs are trained on a subset of imaging modalities and focus primarily on high-resource languages, thus limiting their generalizability and clinical utility. To address these limitations, we introduce a novel Vietnamese-language multimodal medical dataset consisting of 2,757whole-body PET/CT volumes from independent patients and their corresponding full-length clinical reports. This dataset is designed to fill two pressing gaps in medical AI development: (1) the lack of PET/CT imaging data in existing VLMs training corpora, which hinders the development of models capable of handling functional imaging tasks; and (2) the underrepresentation of low-resource languages, particularly the Vietnamese language, in medical vision-language research.
Second-Order Convergence in Private Stochastic Non-Convex Optimization
We investigate the problem of finding second-order stationary points (SOSP) in differentially private (DP) stochastic non-convex optimization. Existing methods suffer from two key limitations: (i) inaccurate convergence error rate due to overlooking gradient variance in the saddle point escape analysis, and (ii) dependence on auxiliary private model selection procedures for identifying DP-SOSP, which can significantly impair utility, particularly in distributed settings. To address these issues, we propose a generic perturbed stochastic gradient descent (PSGD) framework built upon Gaussian noise injection and general gradient oracles. A core innovation of our framework is using model drift distance to determine whether PSGD escapes saddle points, ensuring convergence to approximate local minima without relying on second-order information or additional DP-SOSP identification. By leveraging the adaptive DP-SPIDER estimator as a specific gradient oracle, we develop a new DP algorithm that rectifies the convergence error rates reported in prior work. We further extend this algorithm to distributed learning with heterogeneous data, providing the first formal guarantees for finding DP-SOSP in such settings. Our analysis also highlights the detrimental impacts of private selection procedures in distributed learning under high-dimensional models, underscoring the practical benefits of our design.
Unlocking for Data Analysis Code Generation via Non Parametric Knowledge Distillation
Knowledge distillation from Large Language Models (LLMs) to locally hosted Small Language Models (SLMs) provides advantages for Data Analysis Code Generation (DACG) such as privacy protection. However, achieving effective distillation without resource-intensive training is challenging. This paper investigates whether LLMs can distill knowledge to SLMs through In-Context Learning (ICL), a training-free method for rapid task adaptation. We present the DARGO: Distillation and Adaptive Reasoning-Guided Orchestration framework, which facilitates automatic knowledge distillation from LLMs to SLMs. DARGO consists of three phases: exploration through an Model Orchestration Interface (MOI), Memory Collection of successful trajectories, and Knoweldge-driven Inference. We evaluate DARGO on three challenging DACG benchmarks (WIKITQ, TABMWP, and BIRD-SQL), each with in-domain training sets that enable detailed analysis of knowledge distillation effectiveness. DARGO demonstrates a substantial relative performance improvement of 27.5% on average for the student SLMs. To further observe generalization capabilities, we evaluate the DARGO across different teacher-student model combinations, knowledge transfer scenarios, and unified memory approaches for more advanced, test-only data analysis tasks. Our findings contribute a novel perspective on distillation methods that enhance performance for SLMs while avoiding intensive fine-tuning.
Interpretable Next-token Prediction via the Generalized Induction Head
While large transformer models excel in predictive performance, their lack of interpretability restricts their usefulness in high-stakes domains. To remedy this, we propose the Generalized Induction-Head Model (GIM), an interpretable model for next-token prediction inspired by the observation of "induction heads" in LLMs. GIM is a retrieval-based module that identifies similar sequences in the input context by combining exact n-gram matching and fuzzy matching based on a neural similarity metric. We evaluate GIM in two settings: language modeling and fMRI response prediction. In language modeling, GIM improves next-token prediction by up to 25%p over interpretable baselines, significantly narrowing the gap with black-box LLMs. In an fMRI setting, GIM improves neural response prediction by 20% and offers insight into the language selectivity of the brain. GIM represents a significant step toward uniting interpretability and performance across domains.
Seeds of Structure: Patch PCAReveals Universal Compositional Cues in Diffusion Models
Diffusion models transform random noise into images of remarkable fidelity, yet the structure of this noise-to-image map remains largely unexplored. We investigate this relationship using patch-wise Principal Component Analysis (PCA) and empirically demonstrate that low-frequency components of the initial noise predominantly influence the compositional structure of generated images. Our analyses reveal that noise seeds inherently contain universal compositional cues, evident when identical seeds produce images with similar structural attributes across different datasets and model architectures. Leveraging these insights, we develop and theoretically justify a simple yet effective Patch PCA denoiser that extracts underlying structure from noise using only generic natural image statistics. The robustness of these structural cues is observed to persist across both pixel-space models and latent diffusion models, highlighting their fundamental nature. Finally, we introduce a zero-shot editing method that enables injecting compositional control over generated images, providing an intuitive approach to guided generation without requiring model fine-tuning or additional training.
SimpleStrat: Diversifying Language Model Generation with Stratification
Generating diverse responses from large language models (LLMs) is crucial for applications such as adversarial testing, search, and synthetic data generation, where diversity provides distinct answers across generations. Previous approaches rely solely on increasing the temperature, sacrificing quality. Furthermore, the model's next-token probabilities may not be representative of the true answer distribution. To combat these challenges, we propose SimpleStrat, an alternative that uses the language sample. To model measure itself resampling to partition divers the ity solution, we introduce space int Co o verageQA, strata from a dataset which of to underspecified questions with multiple equally plausible answers. We propose measuring resampling diversity as the KLDivergence between the response distribution and the uniform distribution over valid ground truth answers and use recall as an alternative when assessing proprietary models. On CoverageQA, SimpleStrat improves diversity across all temperatures, showing orthogonal benefits. Quantifiably, we achieve as much as 4X better recall when applied to GPT-4o, and an average reLineduction in KL divergence by 0.36 when applied to Llama 3. Furthermore, we showthat SimpleStrat achieves more resampling diversity at temperature T=0 than scaling and temperature dataset available to T=1 at on https://github.com/j
Diffusing DeBias: Synthetic Bias Amplification for Model Debiasing
The effectiveness of deep learning models in classification tasks is often challenged by the quality and quantity of training data whenever they are affected by strong spurious correlations between specific attributes and target labels. This results in a form of bias affecting training data, which typically leads to unrecoverable weak generalization in prediction. This paper addresses this problem by leveraging bias amplification with generated synthetic data only: we introduce Diffusing DeBias (DDB), a novel approach acting as a plug-in for common methods of unsupervised model debiasing, exploiting the inherent bias-learning tendency of diffusion models in data generation. Specifically, our approach adopts conditional diffusion models to generate synthetic bias-aligned images, which fully replace the original training set for learning an effective bias amplifier model to be subsequently incorporated into an end-to-end and a two-step unsupervised debiasing approach. By tackling the fundamental issue of bias-conflicting training samples' memorization in learning auxiliary models, typical of this type of technique, our proposed method outperforms the current state-of-the-art in multiple benchmark datasets, demonstrating its potential as a versatile and effective tool for tackling bias in deep learning models.
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Hybrid Re-matching for Continual Learning with Parameter-efficient Tuning
Continual learning seeks to enable a model to assimilate knowledge from nonstationary data streams without catastrophic forgetting. Recently, methods based on Parameter-Efficient Tuning (PET) have achieved superior performance without even storing any historical exemplars, which train much fewer specific parameters for each task upon a frozen pre-trained model, and tailored parameters are retrieved to guide predictions during inference. However, reliance solely on pretrained features for parameter matching exacerbates the inconsistency between the training and inference phases, thereby constraining the overall performance. To address this issue, we propose HRM-PET, which makes full use of the richer downstream knowledge inherently contained in the trained parameters. Specifically, we introduce a hybrid re-matching mechanism, which benefits from the initial predicted distribution to facilitate the parameter selections. The direct rematching addresses misclassified samples identified with correct task identity in prediction, despite incorrect initial matching. Moreover, the confidence-based re-matching is specifically designed to handle other more challenging mismatched samples that cannot be calibrated by the former. Besides, to acquire task-invariant knowledge for better matching, we integrate a cross-task instance relationship distillation module into the PET-based method. Extensive experiments conducted on four datasets under five pre-trained settings demonstrate that HRM-PET performs favorably against the state-of-the-art methods.