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NeuralPLexer3: Accurate Biomolecular Complex Structure Prediction with Flow Models

Neural Information Processing Systems

Biomolecular structure determination is essential to a mechanistic understanding of diseases and the development of novel therapeutics. Machine-learning-based structure prediction methods have made significant advancements by computationally predicting protein and bioassembly structures from sequences and molecular topology alone. Despite substantial progress in the field, challenges remain to deliver structure prediction models to real-world drug discovery. Here, we present NeuralPLexer3 -- a physics-inspired flow-based generative model that achieves state-of-the-art prediction accuracy on key biomolecular interaction types and improves training and sampling efficiency compared to its predecessors and alternative methodologies.


Interview with AAAI Fellow Sanmay Das: multiagent systems

AIHub

Each year the AAAI recognizes a group of individuals who have made significant, sustained contributions to the field of artificial intelligence by appointing them as Fellows. We're talking to some of the 2026 AAAI Fellows to find out more about their work. In this interview, we chat to Sanmay Das, who was elected as a Fellow . Could you start with a quick introduction, where you work, and your general area of research? Broadly speaking, I work in multiagent systems. I've done a lot of work at the intersection of AI and economics, and over the last decade or so I've thought a lot about projects in the AI for social impact and social good space. In particular, my interest has been in the allocation of scarce societal resources, thinking about how AI can be integrated, and what it tells us about systems where we don't necessarily want full free market resource allocation.


Two Crew Members Rescued as U.S. Army Helicopter Crashes Near Strait of Hormuz

TIME - Tech

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The Ocean's Health Is Deteriorating on Multiple Fronts, U.N. Scientists Warn

TIME - Tech

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Invasion of flesh-eating parasites triggers quarantines in multiple US counties as deadly outbreak spreads

Daily Mail - Science & tech

'Record the faces': Tense moment NBA boss gives VERY honest take on Trump attending Knicks game Outrage as Netanyahu is caught SPYING on Trump's Iran negotiators... as JD Vance reveals a chilling truth about Israel Teacher convicted of sexual misconduct with boy, 17, sent victim disgraceful texts complaining about her HUSBAND after he warned her that her'hotness' would cause trouble Everyone always said I cleared my throat a lot. But then I developed shoulder pain and doctors discovered the sinister cause... the world's deadliest cancer. Don't leave it too late like I did White couple gave birth to'non-Caucasian' baby. Gaming influencer Alex Cimo dies'very suddenly' aged 32 just a month after'refusing to accept his fate' Girl, 13, mistakenly told she was DYING after Oregon hospital staff made jaw-dropping surgical mistake, parents' $17m lawsuit alleges Karmelo Anthony's parents seen leaving the courtroom in tears just before son's defense team pulls shock move Grim-faced former Louisiana mayor Misty Roberts arrives in court for sentencing after being found guilty of having sex with son's teenage friend The porn-fuelled fantasy middle-class husbands are desperate to try with their wives... and it almost always ends in divorce: JANA HOCKING Meghan Markle's As Ever website has had'less than 400,000 US visitors' since January - as Duchess launches collaboration with a lifestyle influencer to plug her products Nashville's most-hated influencer sparked outrage with sick posts about teen girl who vanished into the woods after a party... now his incredible life of luxury is unraveling No one will admit the sleazy truth about skinny Serena Williams's sudden return to tennis. Call me evil... but I'm exposing her: LIZ JONES Massive twist in JPMorgan'sex slave' case as accuser unveils NEW dossier of wild claims: 'The story is about to change dramatically' Multiple counties in Texas have been quarantined as a potentially deadly infestation that can infect people has crossed the US border and is spreading through the South.


Design tweaks promote responsible AI use for environmental protection, research shows

AIHub

Artificial intelligence systems that ask users to pause to consider AI's energy consumption and environmental impacts are likely to reduce unnecessary AI use, new research by Oregon State University suggests. The findings, published in Science Communication, are important as AI is already using electricity on scales that can be meaningfully compared to households, factories and towns. For example, the electricity needed to train a large language model would power 120 homes for a year, the researchers note; one AI-generated image has roughly the same energy cost as charging a smartphone. With about 85% of the world's energy still coming from fossil fuels, every megawatt-hour that can be carved from AI's electricity profile is significant, says the study's leader, Cheng "Chris" Chen of the OSU College of Liberal Arts. "Despite AI's substantial environmental impacts, information about those impacts is rarely disclosed or effectively communicated to everyday users of AI systems," said Chen, assistant professor in the School of Communication.


I can't wait for this new Chrome security feature to take off

PCWorld

PCWorld reports Chrome's new'Device Bound Session Credentials' feature is now available for Google accounts and Workspace users to combat session hijacking. This security enhancement binds login cookies to specific devices, making stolen cookies useless to hackers even after successful authentication. The feature provides crucial protection beyond existing measures like passkeys and two-factor authentication, offering developers a standardized implementation method. As good as passkeys and two-factor authentication are, they can't fully prevent someone from breaking into (and possibly stealing) an account. But a new feature in Chrome should make that possibility much harder--provided website operators start making use of it.


Samsung's Odyssey G51F is now 160. Score 1440p/180Hz for cheap

PCWorld

When you purchase through links in our articles, we may earn a small commission. Samsung's Odyssey G51F is now $160. Samsung's 27-inch Odyssey G51F with 1440p resolution and 180Hz refresh rate is a budget win now that it's $160 (was $250) at Amazon. Samsung's 27-inch Odyssey G51F gaming monitor is down to $159.99 at Amazon, roughly 36% off its original $249.99 price. Budget gamers looking to upgrade from 1080p should consider it.


Congratulations to the #AAMAS2026 best paper award winners

AIHub

The AAMAS 2026 best paper awards were presented at the 25th International Conference on Autonomous Agents and Multiagent Systems, which took place from 25-29 May 2025 in Paphos, Cyprus. Lucy Smith is Senior Managing Editor for AIhub. Lucy Smith is Senior Managing Editor for AIhub. Eleanor Drage speaks with Tara Merk about how community-owned data centers could transform digital ownership and challenge the dominance of Big Tech. We find out more about multi-agent research for the allocation of scarce societal resources.


Forthcoming machine learning and AI seminars: June 2026 edition

AIHub

This post contains a list of the AI-related seminars that are scheduled to take place between 1 June and 31 July 2026. All events detailed here are free and open for anyone to attend virtually. Franco Accordino and Monika Lanzenberger (European Commission) The Digital Humanism (DIGHUM) Initiative The talk will be livestreamed on YouTube here . K Madhava Krishna (IIIT Hyderabad) Robotics Café The Google Meet link is here . Gianfranco Polizzi (University of Birmingham) Raspberry PI Sign up here to join.