We describe a computational model of the development and regeneration of specific eye-brain circuits. The model comprises a self-organizing map-forming network which uses local Hebb rules, constrained by (genetically determined) molecular markers. Various simulations of the development and regeneration of eye-brain maps in fish and frogs are described, in particular successful simulations of experiments by Schmidt-Cicerone-Easter; Meyer; and Y oon. 1 INTRODUCTION In a previous paper published in last years proceedings (Cowan & Friedman 1990) we outlined a new computational model for the development and regeneration of eye-brain maps. We indicated that such a model can simulate the results of a number of the more complicated surgical manipulations carried out on the visual pathways of goldfish and frogs. In this paper we describe in more detail some of these experiments, and our simulations of them.

Inspired by a visual motion detection model for the ra.bbit retina and by a computational architecture used for early audition in the barn owl, we have designed a chip that employs a correlation model to report the one-dimensional field motion of a scene in real time. Using subthreshold analog VLSI techniques, we have fabricated and successfully tested a 8000 transistor chip using a standard MOSIS process.

Previous work has shown the ability of Multilayer Perceptrons (MLPs) to estimate emission probabilities for Hidden Markov Models (HMMs). The advantages of a speech recognition system incorporating both MLPs and HMMs are the best discrimination and the ability to incorporate multiple sources of evidence (features, temporal context) without restrictive assumptions of distributions or statistical independence. This paper presents results on the speaker-dependent portion of DARPA's English language Resource Management database. Results support the previously reported utility of MLP probability estimation for continuous speech recognition. An additional approach we are pursuing is to use MLPs as nonlinear predictors for autoregressive HMMs. While this is shown to be more compatible with the HMM formalism, it still suffers from several limitations. This approach is generalized to take account of time correlation between successive observations, without any restrictive assumptions about the driving noise. 1 INTRODUCTION We have been working on continuous speech recognition using moderately large vocabularies (1000 words) [1,2].

A novel unsupervised neural network for dimensionality reduction which seeks directions emphasizing multimodality is presented, and its connection to exploratory projection pursuit methods is discussed. This leads to a new statistical insight to the synaptic modification equations governing learning in Bienenstock, Cooper, and Munro (BCM) neurons (1982). The importance of a dimensionality reduction principle based solely on distinguishing features, is demonstrated using a linguistically motivated phoneme recognition experiment, and compared with feature extraction using back-propagation network. 1 Introduction Due to the curse of dimensionality (Bellman, 1961) it is desirable to extract features from a high dimensional data space before attempting a classification. How to perform this feature extraction/dimensionality reduction is not that clear. A first simplification is to consider only features defined by linear (or semi-linear) projections of high dimensional data. This class of features is used in projection pursuit methods (see review in Huber, 1985). Even after this simplification, it is still difficult to characterize what interesting projections are, although it is easy to point at projections that are uninteresting. A statement that has recently been made precise by Diaconis and Freedman (1984) says that for most high-dimensional clouds, most low-dimensional projections are approximately normal. This finding suggests that the important information in the data is conveyed in those directions whose single dimensional projected distribution is far from Gaussian, especially at the center of the distribution.

Combining neuropharmacological experiments with computational modeling, we have shown that cholinergic modulation may enhance associative memory function in piriform (olfactory) cortex. We have shown that the acetylcholine analogue carbachol selectively suppresses synaptic transmission between cells within piriform cortex, while leaving input connections unaffected. When tested in a computational model of piriform cortex, this selective suppression, applied during learning, enhances associative memory performance.

This srudy has demonstrated how artificial neural networks (ANNs) can be used to characterize seismic sources using high-frequency regional seismic data. We have taken the novel approach of using ANNs as a research tool for obtaining seismic source information, specifically depth of focus for earthquakes and ripple-fire characteristics for economic blasts, rather than as just a feature classifier between earthquake and explosion populations. Overall, we have found that ANNs have potential applications to seismic event characterization and identification, beyond just as a feature classifier. In future studies, these techniques should be applied to actual data of regional seismic events recorded at the new regional seismic arrays. The results of this study indicates that an ANN should be evaluated as part of an operational seismic event identification system. 1 INTRODUCTION ANNs have usually been used as pattern matching algorithms, and recent studies have applied ANNs to standard classification between classes of earthquakes and explosions using wavefonn features (Dowla, et al, 1989), (Dysart and Pulli, 1990).

Feedback connections are required so that the teacher signal on the output neurons can modify weights during supervised learning. Relaxation methods are needed for learning static patterns with full-time feedback connections. Feedback network learning techniques have not achieved wide popularity because of the still greater computational efficiency of back-propagation. We show by simulation that relaxation networks of the kind we are implementing in VLSI are capable of learning large problems just like back-propagation networks. A microchip incorporates deterministic mean-field theory learning as well as stochastic Boltzmann learning. A multiple-chip electronic system implementing these networks will make high-speed parallel learning in them feasible in the future.

Barto, Sutton and Watkins [2] introduced a grid task as a didactic example of temporal difference planning and asynchronous dynamical pre gramming. This paper considers the effects of changing the coding of the input stimulus, and demonstrates that the self-supervised learning of a particular form of hidden unit representation improves performance.

Diagnosis of faults in complex, real-time control systems is a complicated task that has resisted solution by traditional methods. We have shown that neural networks can be successfully employed to diagnose faults in digitally controlled powertrain systems. This paper discusses the means we use to develop the appropriate databases for training and testing in order to select the optimum network architectures and to provide reasonable estimates of the classification accuracy of these networks on new samples of data.

Neural network simulations of the dragonfly flight neurocontrol system have been developed to understand how this insect uses complex, unsteady aerodynamics. The simulation networks account for the ganglionic spatial distribution of cells as well as the physiologic operating range and the stochastic cellular fIring history of each neuron. In addition the motor neuron firing patterns, "flight command sequences", were utilized. Simulation training was targeted against both the cellular and flight motor neuron firing patterns. The trained networks accurately resynthesized the intraganglionic cellular firing patterns. These in tum controlled the motor neuron fIring patterns that drive wing musculature during flight. Such networks provide both neurobiological analysis tools and fIrst generation controls for the use of "unsteady" aerodynamics.