The paper investigates a novel approach, based on Constraint Logic Programming (CLP), to predict the 3D conformation of a protein via fragments assembly. The fragments are extracted by a preprocessor-also developed for this work- from a database of known protein structures that clusters and classifies the fragments according to similarity and frequency. The problem of assembling fragments into a complete conformation is mapped to a constraint solving problem and solved using CLP. The constraint-based model uses a medium discretization degree Ca-side chain centroid protein model that offers efficiency and a good approximation for space filling. The approach adapts existing energy models to the protein representation used and applies a large neighboring search strategy. The results shows the feasibility and efficiency of the method. The declarative nature of the solution allows to include future extensions, e.g., different size fragments for better accuracy.

The stable marriage problem is a well-known problem of matching men to women so that no man and woman, who are not married to each other, both prefer each other. Such a problem has a wide variety of practical applications, ranging from matching resident doctors to hospitals, to matching students to schools or more generally to any two-sided market. In the classical stable marriage problem, both men and women express a strict preference order over the members of the other sex, in a qualitative way. Here we consider stable marriage problems with quantitative preferences: each man (resp., woman) provides a score for each woman (resp., man). Such problems are more expressive than the classical stable marriage problems. Moreover, in some real-life situations it is more natural to express scores (to model, for example, profits or costs) rather than a qualitative preference ordering. In this context, we define new notions of stability and optimality, and we provide algorithms to find marriages which are stable and/or optimal according to these notions. While expressivity greatly increases by adopting quantitative preferences, we show that in most cases the desired solutions can be found by adapting existing algorithms for the classical stable marriage problem.

As increasing amounts of sensitive personal information is aggregated into data repositories, it has become important to develop mechanisms for processing the data without revealing information about individual data instances. The differential privacy model provides a framework for the development and theoretical analysis of such mechanisms. In this paper, we propose an algorithm for learning a discriminatively trained multi-class Gaussian classifier that satisfies differential privacy using a large margin loss function with a perturbed regularization term. We present a theoretical upper bound on the excess risk of the classifier introduced by the perturbation.

We study the problem of coalitional manipulation in elections using the unweighted Borda rule. We provide empirical evidence of the manipulability of Borda elections in the form of two new greedy manipulation algorithms based on intuitions from the bin-packing and multiprocessor scheduling domains. Although we have not been able to show that these algorithms beat existing methods in the worst-case, our empirical evaluation shows that they significantly outperform the existing method and are able to find optimal manipulations in the vast majority of the randomly generated elections that we tested. These empirical results provide further evidence that the Borda rule provides little defense against coalitional manipulation.

This paper models a decision support system to predict the occurance of suicide attack in a given collection of cities. The system comprises two parts. First part analyzes and identifies the factors which affect the prediction. Admitting incomplete information and use of linguistic terms by experts, as two characteristic features of this peculiar prediction problem we exploit the Theory of Fuzzy Soft Sets. Hence the Part 2 of the model is an algorithm vz. FSP which takes the assessment of factors given in Part 1 as its input and produces a possibility profile of cities likely to receive the accident. The algorithm is of O(2^n) complexity. It has been illustrated by an example solved in detail. Simulation results for the algorithm have been presented which give insight into the strengths and weaknesses of FSP. Three different decision making measures have been simulated and compared in our discussion.

We present several applications of non-linear data modeling, using principal manifolds and principal graphs constructed using the metaphor of elasticity (elastic principal graph approach). These approaches are generalizations of the Kohonen's self-organizing maps, a class of artificial neural networks. On several examples we show advantages of using non-linear objects for data approximation in comparison to the linear ones. We propose four numerical criteria for comparing linear and non-linear mappings of datasets into the spaces of lower dimension. The examples are taken from comparative political science, from analysis of high-throughput data in molecular biology, from analysis of dynamical systems.

Our research focuses on analysing human activities according to a known behaviorist scenario, in case of noisy and high dimensional collected data. The data come from the monitoring of patients with dementia diseases by wearable cameras. We define a structural model of video recordings based on a Hidden Markov Model. New spatio-temporal features, color features and localization features are proposed as observations. First results in recognition of activities are promising.

Lifted inference, handling whole sets of indistinguishable objects together, is critical to the effective application of probabilistic relational models to realistic real world tasks. Recently, lifted belief propagation (LBP) has been proposed as an efficient approximate solution of this inference problem. It runs a modified BP on a lifted network where nodes have been grouped together if they have — roughly speaking — identical computation trees, the tree-structured “unrolling” of the underlying graph rooted at the nodes. In many situations, this purely syntactic criterion is too pessimistic: message errors decay along paths. Intuitively, for a long chain graph with weak edge potentials, distant nodes will send and receive identical messages yet their computation trees are quite different. To overcome this, we propose iLBP, a novel, easy-to-implement, informed LBP approach that interleaves lifting and modified BP iterations. In turn, we can efficiently monitor the true BP messages sent and received in each iteration and group nodes accordingly. As our experiments show, iLBP can yield significantly faster more lifted network while not degrading performance. Above all, we show that iLBP is faster than BP when solving the problem of distributing data to a large network, an important real-world application where BP is faster than uninformed LBP.

Many problems require repeated inference on probabilistic graphical models, with different values for evidence variables or other changes. Examples of such problems include utility maximization, MAP inference, online and interactive inference, parameter and structure learning, and dynamic inference. Since small changes to the evidence typically only affect a small region of the network, repeatedly performing inference from scratch can be massively redundant. In this paper, we propose expanding frontier belief propagation (EFBP), an efficient approximate algorithm for probabilistic inference with incremental changes to the evidence (or model). EFBP is an extension of loopy belief propagation (BP) where each run of inference reuses results from the previous ones, instead of starting from scratch with the new evidence; messages are only propagated in regions of the network affected by the changes. We provide theoretical guarantees bounding the difference in beliefs generated by EFBP and standard BP, and apply EFBP to the problem of expected utility maximization in influence diagrams. Experiments on viral marketing and combinatorial auction problems show that EFBP can converge much faster than BP without significantly affecting the quality of the solutions.

Lifting can greatly reduce the cost of inference on first-order probabilistic graphical models, but constructing the lifted network can itself be quite costly. In online applications (e.g., video segmentation) repeatedly constructing the lifted network for each new inference can be extremely wasteful, because the evidence typically changes little from one inference to the next. The same is true in many other problems that require repeated inference, like utility maximization, MAP inference, interactive inference, parameter and structure learning, etc. In this paper, we propose an efficient algorithm for updating the structure of an existing lifted network with incremental changes to the evidence. This allows us to construct the lifted network once for the initial inference problem, and amortize the cost over the subsequent problems. Experiments on video segmentation and viral marketing problems show that the algorithm greatly reduces the cost of inference without affecting the quality of the solutions.