Machine Learning competitions such as the Netflix Prize have proven reasonably successful as a method of “crowdsourcing” prediction tasks. But these compe- titions have a number of weaknesses, particularly in the incentive structure they create for the participants. We propose a new approach, called a Crowdsourced Learning Mechanism, in which participants collaboratively “learn” a hypothesis for a given prediction task. The approach draws heavily from the concept of a prediction market, where traders bet on the likelihood of a future event. In our framework, the mechanism continues to publish the current hypothesis, and par- ticipants can modify this hypothesis by wagering on an update. The critical in- centive property is that a participant will profit an amount that scales according to how much her update improves performance on a released test set.

Motivated by applications in electronic games as well as teaching systems, we investigate the problem of dynamic difficulty adjustment. The task here is to repeatedly find a game difficulty setting that is neither `too easy' and bores the player, nor `too difficult' and overburdens the player. The contributions of this paper are ($i$) formulation of difficulty adjustment as an online learning problem on partially ordered sets, ($ii$) an exponential update algorithm for dynamic difficulty adjustment, ($iii$) a bound on the number of wrong difficulty settings relative to the best static setting chosen in hindsight, and ($iv$) an empirical investigation of the algorithm when playing against adversaries.

We consider the problem of estimating neural spikes from extracellular voltage recordings. Most current methods are based on clustering, which requires substantial human supervision and produces systematic errors by failing to properly handle temporally overlapping spikes. We formulate the problem as one of statistical inference, in which the recorded voltage is a noisy sum of the spike trains of each neuron convolved with its associated spike waveform. Joint maximum-a-posteriori (MAP) estimation of the waveforms and spikes is then a blind deconvolution problem in which the coefficients are sparse. We develop a block-coordinate descent method for approximating the MAP solution. We validate our method on data simulated according to the generative model, as well as on real data for which ground truth is available via simultaneous intracellular recordings. In both cases, our method substantially reduces the number of missed spikes and false positives when compared to a standard clustering algorithm, primarily by recovering temporally overlapping spikes. The method offers a fully automated alternative to clustering methods that is less susceptible to systematic errors.

Variability in single neuron models is typically implemented either by a stochastic Leaky-Integrate-and-Fire model or by a model of the Generalized Linear Model (GLM) family. We use analytical and numerical methods to relate state-of-the-art models from both schools of thought. First we find the analytical expressions relating the subthreshold voltage from the Adaptive Exponential Integrate-and-Fire model (AdEx) to the Spike-Response Model with escape noise (SRM as an example of a GLM). Then we calculate numerically the link-function that provides the firing probability given a deterministic membrane potential. We find a mathematical expression for this link-function and test the ability of the GLM to predict the firing probability of a neuron receiving complex stimulation. Comparing the prediction performance of various link-functions, we find that a GLM with an exponential link-function provides an excellent approximation to the Adaptive Exponential Integrate-and-Fire with colored-noise input. These results help to understand the relationship between the different approaches to stochastic neuron models.

We study the problem of learning to track a large quantity of homogeneous objects such as cell tracking in cell culture study and developmental biology. Reliable cell tracking in time-lapse microscopic image sequences is important for modern biomedical research. Existing cell tracking methods are usually kept simple and use only a small number of features to allow for manual parameter tweaking or grid search. We propose a structured learning approach that allows to learn optimum parameters automatically from a training set. This allows for the use of a richer set of features which in turn affords improved tracking compared to recently reported methods on two public benchmark sequences.

Nonparametric Bayesian methods are developed for analysis of multi-channel spike-train data, with the feature learning and spike sorting performed jointly. The feature learning and sorting are performed simultaneously across all channels. Dictionary learning is implemented via the beta-Bernoulli process, with spike sorting performed via the dynamic hierarchical Dirichlet process (dHDP), with these two models coupled. The dHDP is augmented to eliminate refractory-period violations, it allows the "appearance" and "disappearance" of neurons over time, and it models smooth variation in the spike statistics.

Multi-task learning (MTL) learns multiple related tasks simultaneously to improve generalization performance. Alternating structure optimization (ASO) is a popular MTL method that learns a shared low-dimensional predictive structure on hypothesis spaces from multiple related tasks. It has been applied successfully in many real world applications. As an alternative MTL approach, clustered multi-task learning (CMTL) assumes that multiple tasks follow a clustered structure, i.e., tasks are partitioned into a set of groups where tasks in the same group are similar to each other, and that such a clustered structure is unknown a priori. The objectives in ASO and CMTL differ in how multiple tasks are related. Interestingly, we show in this paper the equivalence relationship between ASO and CMTL, providing significant new insights into ASO and CMTL as well as their inherent relationship. The CMTL formulation is non-convex, and we adopt a convex relaxation to the CMTL formulation. We further establish the equivalence relationship between the proposed convex relaxation of CMTL and an existing convex relaxation of ASO, and show that the proposed convex CMTL formulation is significantly more efficient especially for high-dimensional data. In addition, we present three algorithms for solving the convex CMTL formulation. We report experimental results on benchmark datasets to demonstrate the efficiency of the proposed algorithms.

In recent years, a rich variety of shrinkage priors have been proposed that have great promise in addressing massive regression problems. In general, these new priors can be expressed as scale mixtures of normals, but have more complex forms and better properties than traditional Cauchy and double exponential priors. We first propose a new class of normal scale mixtures through a novel generalized beta distribution that encompasses many interesting priors as special cases. This encompassing framework should prove useful in comparing competing priors, considering properties and revealing close connections. We then develop a class of variational Bayes approximations through the new hierarchy presented that will scale more efficiently to the types of truly massive data sets that are now encountered routinely.

Discriminative learning when training and test data belong to different distributions is a challenging and complex task. Often times we have very few or no labeled data from the test or target distribution but may have plenty of labeled data from multiple related sources with different distributions. The difference in distributions may be both in marginal and conditional probabilities. Most of the existing domain adaptation work focuses on the marginal probability distribution difference between the domains, assuming that the conditional probabilities are similar. However in many real world applications, conditional probability distribution differences are as commonplace as marginal probability differences. In this paper we propose a two-stage domain adaptation methodology which combines weighted data from multiple sources based on marginal probability differences (first stage) as well as conditional probability differences (second stage), with the target domain data. The weights for minimizing the marginal probability differences are estimated independently, while the weights for minimizing conditional probability differences are computed simultaneously by exploiting the potential interaction among multiple sources. We also provide a theoretical analysis on the generalization performance of the proposed multi-source domain adaptation formulation using the weighted Rademacher complexity measure. Empirical comparisons with existing state-of-the-art domain adaptation methods using three real-world datasets demonstrate the effectiveness of the proposed approach.

Topic models have the potential to improve search and browsing by extracting useful semantic themes from web pages and other text documents. When learned topics are coherent and interpretable, they can be valuable for faceted browsing, results set diversity analysis, and document retrieval. However, when dealing with small collections or noisy text (e.g. web search result snippets or blog posts), learned topics can be less coherent, less interpretable, and less useful. To overcome this, we propose two methods to regularize the learning of topic models. Our regularizers work by creating a structured prior over words that reflect broad patterns in the external data. Using thirteen datasets we show that both regularizers improve topic coherence and interpretability while learning a faithful representation of the collection of interest. Overall, this work makes topic models more useful across a broader range of text data.