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AnyECG-Lab: An Exploration Study of Fine-tuning an ECG Foundation Model to Estimate Laboratory Values from Single-Lead ECG Signals

arXiv.org Artificial Intelligence

Timely access to laboratory values is critical for clinical decision-making, yet current approaches rely on invasive venous sampling and are intrinsically delayed. Electrocardiography (ECG), as a non-invasive and widely available signal, offers a promising modality for rapid laboratory estimation. Recent progress in deep learning has enabled the extraction of latent hematological signatures from ECGs. However, existing models are constrained by low signal-to-noise ratios, substantial inter-individual variability, limited data diversity, and suboptimal generalization, especially when adapted to low-lead wearable devices. In this work, we conduct an exploratory study leveraging transfer learning to fine-tune ECGFounder, a large-scale pre-trained ECG foundation model, on the Multimodal Clinical Monitoring in the Emergency Department (MC-MED) dataset from Stanford. We generated a corpus of more than 20 million standardized ten-second ECG segments to enhance sensitivity to subtle biochemical correlates. On internal validation, the model demonstrated strong predictive performance (area under the curve above 0.65) for thirty-three laboratory indicators, moderate performance (between 0.55 and 0.65) for fifty-nine indicators, and limited performance (below 0.55) for sixteen indicators. This study provides an efficient artificial-intelligence driven solution and establishes the feasibility scope for real-time, non-invasive estimation of laboratory values.


Does Homophily Help in Robust Test-time Node Classification?

arXiv.org Artificial Intelligence

Homophily, the tendency of nodes from the same class to connect, is a fundamental property of real-world graphs, underpinning structural and semantic patterns in domains such as citation networks and social networks. Existing methods exploit homophily through designing homophily-aware GNN architectures or graph structure learning strategies, yet they primarily focus on GNN learning with training graphs. However, in real-world scenarios, test graphs often suffer from data quality issues and distribution shifts, such as domain shifts across users from different regions in social networks and temporal evolution shifts in citation network graphs collected over varying time periods. These factors significantly compromise the pre-trained model's robustness, resulting in degraded test-time performance. With empirical observations and theoretical analysis, we reveal that transforming the test graph structure by increasing homophily in homophilic graphs or decreasing it in heterophilic graphs can significantly improve the robustness and performance of pre-trained GNNs on node classifications, without requiring model training or update. Motivated by these insights, a novel test-time graph structural transformation method grounded in homophily, named GrapHoST, is proposed. Specifically, a homophily predictor is developed to discriminate test edges, facilitating adaptive test-time graph structural transformation by the confidence of predicted homophily scores. Extensive experiments on nine benchmark datasets under a range of test-time data quality issues demonstrate that GrapHoST consistently achieves state-of-the-art performance, with improvements of up to 10.92%. Our code has been released at https://github.com/YanJiangJerry/GrapHoST.


Machine Learning Enabled Early Warning System For Financial Distress Using Real-Time Digital Signals

arXiv.org Artificial Intelligence

International Journal of Applied Mathematics Volume 38 No. 5 s, 2025 ISSN: 1311 - 1728 (printed version); ISSN: 1314 - 8060 (on - line version) Received: August 0 7, 2025 550 Abstract The growing instability of both global and domestic economic environments has increased the risk of financial distress at the household level. However, traditional econometric models often rely on delayed and aggregated data, limiting their effectiveness. This study introduces a machine learning - based early warning system that utilizes real - time digital and macroeconomic signals to identify financial distress in near real - time. Using a panel dataset of 750 households tracked over three monitoring rounds spa nning 13 months, the framework combines socioeconomic attributes, macroeconomic indicators (such as GDP growth, inflation, and foreign exchange fluctuations), and digital economy measures (including ICT demand and market volatility). Through data preproces sing and feature engineering, we introduce lagged variables, volatility measures, and interaction terms to capture both gradual and sudden changes in financial stability. We benchmark baseline classifiers, such as logistic regression and decision trees, ag ainst advanced ensemble models including random forests, XGBoost, and LightGBM. Our results indicate that the engineered features from the digital economy significantly enhance predictive accuracy. The system performs reliably for both binary distress dete ction and multi - class severity classification, with SHAP - based explanations identifying inflation volatility and ICT demand as key predictors. Crucially, the framework is International Journal of Applied Mathematics Volume 38 No. 5 s, 2025 ISSN: 1311 - 1728 (printed version); ISSN: 1314 - 8060 (on - line version) Received: August 0 7, 2025 551 By implementing machine learning in a transparent and interpretable manner, this study demonstrates the feasibility and impact of providing near - real - time early warnings of financial distress. This offers actionable insights that can strengthen household resilience and guide preemptive intervention strategies. Keywords: Financial Distress, Early Warning Systems, Machine Learning, Digital Economy, Temporal Classification, Explainable AI 1. Introduction 1.1 Background and Motivation The prediction of financial distress has long been recognized as a critical element for ensuring economic resilience and mitigating systemic risk across households, firms, and national economies.


Supervised Fine-Tuning or In-Context Learning? Evaluating LLMs for Clinical NER

arXiv.org Artificial Intelligence

We study clinical Named Entity Recognition (NER) on the CADEC corpus and compare three families of approaches: (i) BERT-style encoders (BERT Base, BioClinicalBERT, RoBERTa-large), (ii) GPT-4o used with few-shot in-context learning (ICL) under simple vs.\ complex prompts, and (iii) GPT-4o with supervised fine-tuning (SFT). All models are evaluated on standard NER metrics over CADEC's five entity types (ADR, Drug, Disease, Symptom, Finding). RoBERTa-large and BioClinicalBERT offer limited improvements over BERT Base, showing the limit of these family of models. Among LLM settings, simple ICL outperforms a longer, instruction-heavy prompt, and SFT achieves the strongest overall performance (F1 $\approx$ 87.1%), albeit with higher cost. We find that the LLM achieve higher accuracy on simplified tasks, restricting classification to two labels.


Adapting Noise-Driven PUF and AI for Secure WBG ICS: A Proof-of-Concept Study

arXiv.org Artificial Intelligence

Wide-bandgap (WBG) technologies offer unprecedented improvements in power system efficiency, size, and performance, but also introduce unique sensor corruption and cybersecurity risks in industrial control systems (ICS), particularly due to high-frequency noise and sophisticated cyber-physical threats. This proof-of-concept (PoC) study demonstrates the adaptation of a noise-driven physically unclonable function (PUF) and machine learning (ML)-assisted anomaly detection framework to the demanding environment of WBG-based ICS sensor pathways. By extracting entropy from unavoidable WBG switching noise (up to 100 kHz) as a PUF source, and simultaneously using this noise as a real-time threat indicator, the proposed system unites hardware-level authentication and anomaly detection. Our approach integrates hybrid machine learning (ML) models with adaptive Bayesian filtering, providing robust and low-latency detection capabilities resilient to both natural electromagnetic interference (EMI) and active adversarial manipulation. Through detailed simulations of WBG modules under benign and attack scenarios--including EMI injection, signal tampering, and node impersonation--we achieve 95% detection accuracy and sub-millisecond processing latency. These results demonstrate the feasibility of physics-driven, dual-use noise exploitation as a scalable ICS defense primitive. Our findings lay the groundwork for next-generation security strategies that leverage inherent device characteristics, bridging hardware and artificial intelligence (AI) for enhanced protection of critical ICS infrastructure.


CityRiSE: Reasoning Urban Socio-Economic Status in Vision-Language Models via Reinforcement Learning

arXiv.org Artificial Intelligence

Harnessing publicly available, large-scale web data, such as street view and satellite imagery, urban socio-economic sensing is of paramount importance for achieving global sustainable development goals. With the emergence of Large Vision-Language Models (LVLMs), new opportunities have arisen to solve this task by treating it as a multi-modal perception and understanding problem. However, recent studies reveal that LVLMs still struggle with accurate and interpretable socio-economic predictions from visual data. To address these limitations and maximize the potential of LVLMs, we introduce \textbf{CityRiSE}, a novel framework for \textbf{R}eason\textbf{i}ng urban \textbf{S}ocio-\textbf{E}conomic status in LVLMs through pure reinforcement learning (RL). With carefully curated multi-modal data and verifiable reward design, our approach guides the LVLM to focus on semantically meaningful visual cues, enabling structured and goal-oriented reasoning for generalist socio-economic status prediction. Experiments demonstrate that CityRiSE with emergent reasoning process significantly outperforms existing baselines, improving both prediction accuracy and generalization across diverse urban contexts, particularly for prediction on unseen cities and unseen indicators. This work highlights the promise of combining RL and LVLMs for interpretable and generalist urban socio-economic sensing.


SteerX: Disentangled Steering for LLM Personalization

arXiv.org Artificial Intelligence

Large language models (LLMs) have shown remarkable success in recent years, enabling a wide range of applications, including intelligent assistants that support users' daily life and work. A critical factor in building such assistants is personalizing LLMs, as user preferences and needs vary widely. Activation steering, which directly leverages directions representing user preference in the LLM activation space to adjust its behavior, offers a cost-effective way to align the model's outputs with individual users. However, existing methods rely on all historical data to compute the steering vector, ignoring that not all content reflects true user preferences, which undermines the personalization signal. To address this, we propose SteerX, a disentangled steering method that isolates preference-driven components from preference-agnostic components. Grounded in causal inference theory, SteerX estimates token-level causal effects to identify preference-driven tokens, transforms these discrete signals into a coherent description, and then leverages them to steer personalized LLM generation. By focusing on the truly preference-driven information, SteerX produces more accurate activation steering vectors and enhances personalization. Experiments on two representative steering backbone methods across real-world datasets demonstrate that SteerX consistently enhances steering vector quality, offering a practical solution for more effective LLM personalization.


Real-Time Semantic Segmentation on FPGA for Autonomous Vehicles Using LMIINet with the CGRA4ML Framework

arXiv.org Artificial Intelligence

Semantic segmentation has emerged as a fundamental problem in computer vision, gaining particular importance in real-time applications such as autonomous driving. The main challenge is achieving high accuracy while operating under computational and hardware constraints. In this research, we present an FPGA-based implementation of real-time semantic segmentation leveraging the lightweight LMIINet architecture and the Coarse-Grained Reconfigurable Array for Machine Learning (CGRA4ML) hardware framework. The model was trained using Quantization-Aware Training (QAT) with 8-bit precision on the Cityscapes dataset, reducing memory footprint by a factor of four while enabling efficient fixed-point computations. Necessary modifications were applied to adapt the model to CGRA4ML constraints, including simplifying skip connections, employing hardware-friendly operations such as depthwise-separable and 1A-1 convolutions, and redesigning parts of the Flatten Transformer. Our implementation achieves approximately 90% pixel accuracy and 45% mean Intersection-over-Union (mIoU), operating in real-time at 20 frames per second (FPS) with 50.1 ms latency on the ZCU104 FPGA board. The results demonstrate the potential of CGRA4ML, with its flexibility in mapping modern layers and off-chip memory utilization for skip connections, provides a path for implementing advanced semantic segmentation networks on FPGA for real-time applications to outperform traditional GPU solutions in terms of power efficiency while maintaining competitive accuracy. The code for this project is publicly available at https://github.com/STAmirr/ cgra4ml_semantic_segmentation


PaperAsk: A Benchmark for Reliability Evaluation of LLMs in Paper Search and Reading

arXiv.org Artificial Intelligence

Large Language Models (LLMs) increasingly serve as research assistants, yet their reliability in scholarly tasks remains under-evaluated. In this work, we introduce PaperAsk, a benchmark that systematically evaluates LLMs across four key research tasks: citation retrieval, content extraction, paper discovery, and claim verification. We evaluate GPT-4o, GPT-5, and Gemini-2.5-Flash under realistic usage conditions-via web interfaces where search operations are opaque to the user. Through controlled experiments, we find consistent reliability failures: citation retrieval fails in 48-98% of multi-reference queries, section-specific content extraction fails in 72-91% of cases, and topical paper discovery yields F1 scores below 0.32, missing over 60% of relevant literature. Further human analysis attributes these failures to the uncontrolled expansion of retrieved context and the tendency of LLMs to prioritize semantically relevant text over task instructions. Across basic tasks, the LLMs display distinct failure behaviors: ChatGPT often withholds responses rather than risk errors, whereas Gemini produces fluent but fabricated answers. To address these issues, we develop lightweight reliability classifiers trained on PaperAsk data to identify unreliable outputs. PaperAsk provides a reproducible and diagnostic framework for advancing the reliability evaluation of LLM-based scholarly assistance systems.


CGoT: A Novel Inference Mechanism for Embodied Multi-Agent Systems Using Composable Graphs of Thoughts

arXiv.org Artificial Intelligence

The integration of self-driving cars and service robots is becoming increasingly prevalent across a wide array of fields, playing a crucial and expanding role in both industrial applications and everyday life. In parallel, the rapid advancements in Large Language Models (LLMs) have garnered substantial attention and interest within the research community. This paper introduces a novel vehicle-robot system that leverages the strengths of both autonomous vehicles and service robots. In our proposed system, two autonomous ego-vehicles transports service robots to locations within an office park, where they perform a series of tasks. The study explores the feasibility and potential benefits of incorporating LLMs into this system, with the aim of enhancing operational efficiency and maximizing the potential of the cooperative mechanisms between the vehicles and the robots. This paper proposes a novel inference mechanism which is called CGOT toward this type of system where an agent can carry another agent. Experimental results are presented to validate the performance of the proposed method.