Former Olympian is arrested for allegedly vandalizing Reflecting Pool... but he claims he merely touched it Call me cynical, but the real reason Gruesome Twosome Harry and Meghan are returning to the UK is just so obvious... and highly humiliating: MAUREEN CALLAHAN Three more arrested over bungee jumper's death after she was hurled from bridge without a rope I lost 50lb without jabs using this easy but overlooked method. But I still felt dowdy - until I discovered these expert anti-ageing fashion and beauty tips. Inside America's new fattest town: Burgers are the size of your head, gyms lie empty and custom mobility scooters carry 800lb loads... as we investigate why Ozempic just DOESN'T work Blake Lively runs errands in frumpy outfit after reconciling with ex-BFF Taylor Swift... miles away from reported'bachelorette party' I've spoken to thousands of children who claim they can recall a past life ... these chilling stories have convinced me they're telling the truth Stingy fast food giant named America's favorite restaurant AGAIN... and experts think they know why Ex-partner of dad who was berated for taking his daughters into women's bathroom claims he'exploited' girls and accuses him of failing to pay child support... before he hits back The'marry me' sex move that'll make even the most commitment-phobic of men beg to see you again... and it worked for THREE of my friends America's next real estate time bomb detonates the sun-kissed southern housing dream: 'New condo crisis' sparks chilling warning as it snakes across the nation Furious Trump hits back at Italian Prime Minister Meloni and gives her unusual'nickname' as their photo feud ramps up TV star mom, 46, who appeared on'quitting everything to change your life' show died in fire at luxury Caribbean beach resort that sent 1,700 tourists running for their lives Grace Kelly's lookalike granddaughter, 27, wows in bikini snaps...as she packs on the PDA during beach getaway The four mistakes that led to bungee tragedy on Skeleton Bridge: FRED KELLY saw the scene for himself, now he retraces the prelude to disaster. So was it really an accident? Famous TV mansion left standing after Malibu's harshest wildfires struggled to find a buyer for 14 years but finally sells for an eye-watering price Swedish actress, 81, was in TWO James Bond movies and also worked with Charlton Heston, who is she?

A major challenge in aligning large language models (LLMs) with human preferences is the issue of distribution shift. LLM alignment algorithms rely on static preference datasets, assuming that they accurately represent real-world user preferences. However, user preferences vary significantly across geographical regions, demographics, linguistic patterns, and evolving cultural trends. This preference distribution shift leads to catastrophic alignment failures in many real-world applications. We address this problem using the principled framework of distributionally robust optimization, and develop two novel distributionally robust direct preference optimization (DPO) algorithms, namely, Wasserstein DPO (WDPO) and Kullback-Leibler DPO (KLDPO). We characterize the sample complexity of learning the optimal policy parameters for WDPO and KLDPO. Moreover, we propose scalable gradient descent-style learning algorithms by developing suitable approximations for the challenging minimax loss functions of WDPO and KLDPO. Our empirical experiments using benchmark data sets and LLMs demonstrate the superior performance of WDPO and KLDPO in substantially improving the alignment when there is a preference distribution shift.

We introduce DanmakuTPPBench, a comprehensive benchmark designed to advance multi-modal Temporal Point Process (TPP) modeling in the era of Large Language Models (LLMs). While TPPs have been widely studied for modeling temporal event sequences, existing datasets are predominantly unimodal, hindering progress in models that require joint reasoning over temporal, textual, and visual information. To address this gap, DanmakuTPPBench comprises two complementary components: (1) DanmakuTPP-Events, a novel dataset derived from the Bilibili video platform, where user-generated bullet comments (Danmaku) naturally form multi-modal events annotated with precise timestamps, rich textual content, and corresponding video frames; (2) DanmakuTPP-QA, a challenging question-answering dataset constructed via a novel multi-agent pipeline powered by state-of-the-art LLMs and multi-modal LLMs (MLLMs), targeting complex temporal-textual-visual reasoning. We conduct extensive evaluations using both classical TPP models and recent MLLMs, revealing significant performance gaps and limitations in current methods' ability to model multi-modal event dynamics. Our benchmark establishes strong baselines and calls for further integration of TPP modeling into the multi-modal language modeling landscape.

PCWorld reports AMD is reintroducing three mobile processors from 2019-2020, including Ryzen 3 3100U, Ryzen 5 3501U, and Ryzen 4700LE for budget laptops. This strategy addresses rising PC prices by offering significantly cheaper alternatives to current Ryzen AI 400 series chips through select OEMs in limited volumes. Intel is also rumored to pursue similar re-releases, highlighting industry-wide efforts to provide affordable computing solutions for cost-conscious consumers. AMD has resuscitated three mobile chips from 2019 and 2020 to ship to PC makers asking for cheaper processors for budget PCs, the company confirmed. AMD is now offering the AMD Ryzen 3 3100U and the the Ryzen 5 3501U, based on the Zen+ (Ryzen 3000 Mobile / Picasso) architecture it launched in 2019.

Understanding molecules is key to understanding organisms and driving advances in drug discovery, requiring interdisciplinary knowledge across chemistry and biology. Although large molecular language models have achieved notable success in task transfer, they often struggle to accurately analyze molecular features due to limited knowledge and reasoning capabilities. To address this issue, we present Mol-LLaMA, a large molecular language model that grasps the general knowledge centered on molecules and exhibits explainability and reasoning ability. To this end, we design key data types that encompass the fundamental molecular features, taking into account the essential abilities for molecular reasoning. Further, to improve molecular understanding, we propose a module that integrates complementary information from different molecular encoders, leveraging the distinct advantages of molecular representations. Our experimental results demonstrate that Mol-LLaMA is capable of comprehending the general features of molecules and providing informative responses, implying its potential as a general-purpose assistant for molecular analysis. Our project page is at https://mol-llama.github.io/.

Evaluating the open-form textual responses generated by Large Language Models (LLMs) typically requires measuring the semantic similarity of the response to a (human generated) reference. However, there is evidence that current semantic similarity methods may capture syntactic or lexical forms over semantic content. While benchmarks exist for semantic equivalence, they often suffer from high generation costs due to reliance on subjective human judgment, limited availability for domain-specific applications, and unclear definitions of equivalence. This paper introduces a novel method for generating benchmarks to evaluate semantic similarity methods for LLM outputs, specifically addressing these limitations. Our approach leverages knowledge graphs (KGs) to generate pairs of naturallanguage statements that are semantically similar or dissimilar, with dissimilar pairs categorized into one of four sub-types. We generate benchmark datasets in four different domains (general knowledge, biomedicine, finance, biology), and conduct a comparative study of semantic similarity methods including traditional natural language processing scores and LLM-as-a-judge predictions. We observe that the sub-type of semantic variation, as well as the domain of the benchmark impact the performance of semantic similarity methods, with no method being consistently superior.

Evaluating the open-form textual responses generated by Large Language Models (LLMs) typically requires measuring the semantic similarity of the response to a (human generated) reference. However, there is evidence that current semantic similarity methods may capture syntactic or lexical forms over semantic content. While benchmarks exist for semantic equivalence, they often suffer from high generation costs due to reliance on subjective human judgment, limited availability for domain-specific applications, and unclear definitions of equivalence. This paper introduces a novel method for generating benchmarks to evaluate semantic similarity methods for LLM outputs, specifically addressing these limitations. Our approach leverages knowledge graphs (KGs) to generate pairs of naturallanguage statements that are semantically similar or dissimilar, with dissimilar pairs categorized into one of four sub-types. We generate benchmark datasets in four different domains (general knowledge, biomedicine, finance, biology), and conduct a comparative study of semantic similarity methods including traditional natural language processing scores and LLM-as-a-judge predictions. We observe that the sub-type of semantic variation, as well as the domain of the benchmark impact the performance of semantic similarity methods, with no method being consistently superior.

When instructed to place a floor lamp next to an armchair, humans can visually ground it in the scene, estimating its base diameter and height, imagining its precise alignment with the armchair, and judging whether it fits naturally within the 3D environment. Humans can naturally perceive, reason about, and localize expressions to "anywhere" in 3D scenes. Yet can today's 3D vision-language models ground free-form referring expressions to precise positions and dimensions in a 3D scene, especially when those expressions refer to regions beyond objects? Existing 3D visual grounding models, pretrained on large 3D scene datasets, excel at aligning expressions to objects in a scene [7, 58, 2, 63, 61, 26]. However, these models remain constrained to object-level alignment, with limited attention paid to the broader spatial regions beyond objects.

The growing importance of mRNA therapeutics and synthetic biology highlights the need for models that capture the latent structure of synonymous codon (different triplets encoding the same amino acid) usage, which subtly modulates translation efficiency and gene expression. While recent efforts incorporate codon-level inductive biases through auxiliary objectives, they often fall short of explicitly modeling the structured relationships that arise from the genetic code's inherent symmetries. We introduce Equi-mRNA, the first codon-level equivariant mRNA language model that explicitly encodes synonymous codon symmetries as cyclic subgroups of 2D Special Orthogonal matrix (SO(2)). By combining group-theoretic priors with an auxiliary equivariance loss and symmetry-aware pooling, Equi-mRNA learns biologically grounded representations that outperform vanilla baselines across multiple axes. On downstream property-prediction tasks including expression, stability, and riboswitch switching Equi-mRNA delivers up to 10% improvements in accuracy. In sequence generation, it produces mRNA constructs that are up to 4 more realistic under Fréchet BioDistance metrics and 28% better preserve functional properties compared to vanilla baseline. Interpretability analyses further reveal that learned codon-rotation distributions recapitulate known GC-content biases and tRNA abundance patterns, offering novel insights into codon usage. Equi-mRNA establishes a new biologically principled paradigm for mRNA modeling.

Electronic Health Records (EHR) are time-series relational databases that record patient interactions and medical events over time, serving as a critical resource for healthcare research and applications. However, privacy concerns and regulatory restrictions limit the sharing and utilization of such sensitive data, necessitating the generation of synthetic EHR datasets. Unlike previous EHR synthesis methods--which typically generate medical records consisting of expert-chosen features (e.g., a few vital signs, structured codes only)--we introduce RawMed, the first framework to synthesize multi-table, time-series EHR data that closely resembles raw EHRs.