Recent research shows that in-context learning (ICL) can be effective even when demonstrations have missing or incorrect labels. To shed light on this capability, we examine a canonical setting where the demonstrations are drawn according to a binary Gaussian mixture model (GMM) and a certain fraction of the demonstrations have missing labels.

This comparative summary underscores the breadth, depth, and clinical relevance of PanTS relative to existing public datasets. While a number of prior datasets were incorporated into our training partition, our team made substantial and transformative contributions. Specifically, 23 board-certified radiologists independently annotated and rigorously validated previously unlabeled pancreatic tumors as well as over 25 additional abdominal and thoracic anatomical structures, many of which were not comprehensively labeled in the source datasets. This effort significantly elevates the clinical utility and completeness of the dataset. Scale: With 36,390 CT scans, PanTS is over 8.5 larger than the most extensive existing dataset dedicated to pancreatic tumor detection, setting a new benchmark for scale in abdominal imaging datasets.

PanTS is a large-scale, multi-institutional dataset curated to advance research in pancreatic CT analysis. It contains 36,390 CT scans from 145 medical centers, with expert-validated, voxel-wise annotations of over 993,000 anatomical structures, covering pancreatic tumors, pancreas head, body, and tail, and 24 surrounding anatomical structures such as vascular/skeletal structures and abdominal/thoracic organs. Each scan includes metadata such as patient age, sex, diagnosis, contrast phase, in-plane spacing, slice thickness, etc. AI models trained on PanTS achieve significantly better performance in pancreatic tumor detection, localization, and segmentation than those trained on existing public datasets. Our analysis indicates that these gains are directly attributable to the 16 larger-scale tumor annotations and indirectly supported by the 24 additional surrounding anatomical structures. As the largest and most comprehensive resource of its kind, PanTS offers a new benchmark for developing and evaluating AI models in pancreatic CT analysis.

Conventional representation learning methods learn a universal representation that primarily captures dominant semantics, which may not always align with customized downstream tasks. For instance, in animal habitat analysis, researchers prioritize scene-related features, whereas universal embeddings emphasize categorical semantics, leading to suboptimal results. As a solution, existing approaches resort to supervised fine-tuning, which however incurs high computational and annotation costs. In this paper, we propose Conditional Representation Learning (CRL), aiming to extract representations tailored to arbitrary user-specified criteria. Specifically, we reveal that the semantics of a space are determined by its basis, thereby enabling a set of descriptive words to approximate the basis for a customized feature space. Building upon this insight, given a user-specified criterion, CRL first employs a large language model (LLM) to generate descriptive texts to construct the semantic basis, then projects the image representation into this conditional feature space leveraging a vision-language model (VLM). The conditional representation better captures semantics for the specific criterion, which could be utilized for multiple customized tasks. Extensive experiments on classification and retrieval tasks demonstrate the superiority and generality of the proposed CRL.

Split Federated Learning (SFL) enables scalable training on edge devices by combining the parallelism of Federated Learning (FL) with the computational offloading of Split Learning (SL). Despite its great success, SFL suffers significantly from the well-known straggler issue in distributed learning systems. This problem is exacerbated by the dependency between Split Server and clients: the Split Server side model update relies on receiving activations from clients. Such synchronization requirement introduces significant time latency, making straggler a critical bottleneck to the scalability and efficiency of the system. To mitigate this problem, we propose MU-SplitFed, a straggler-resilient SFL algorithm in zeroth-order optimization that decouples training progress from straggler delays via a simple yet effective unbalanced update mechanism. By enabling the server to perform τ local updates per client round, MU-SplitFed achieves a convergence rate of O( p d/(τT))for non-convex objectives, demonstrating a linear speedup of τ in communication rounds. Experiments demonstrate that MU-SplitFedconsistently outperforms baseline methods with the presence of stragglers and effectively mitigates their impact through adaptive tuning of τ.

Analysis of noninvasive microvascular blood flow can improve the diagnosis, prognosis, and management of many medical conditions, including cardiovascular, peripheral vascular, and sickle cell disease. This paper introduces SAM2Flow, an interactive optical flow estimation model to analyze long Oblique Back-illumination Microscopy (OBM) videos of in vivo microvascular flow. Inspired by the Segment Anything Model (SAM2), SAM2Flow enables users to specify regions of interest through user prompts for focused flow estimation. SAM2Flow also incorporates a dual memory attention mechanism, comprising both motion and context memory, to achieve efficient and stable flow estimations over extended video sequences. According to our experiments, SAM2Flow achieves SOTA accuracy in foreground optical flow estimation on both microvascular flow and public datasets, with a fast inference speed of over 20fps on 512 512inputs. Based on the temporally robust flow estimation, SAM2Flow demonstrated superior performance in downstream physiological applications compared to existing models.

Recent advances in large language models (LLMs) have yielded impressive performance on various tasks, yet they often depend on high-quality feedback that can be costly. Self-refinement methods attempt to leverage LLMs' internal evaluation mechanisms with minimal human supervision; however, these approaches frequently suffer from inherent biases and overconfidence, especially in domains where the models lack sufficient internal knowledge, resulting in performance degradation. As an initial step toward enhancing self-refinement for broader applications, we introduce an iterative refinement pipeline that employs the Unlabeled-Unlabeled learning framework to improve LLM-generated pseudo-labels for classification tasks.

Pre-training has proven effective in addressing data scarcity and performance limitations in solving PDE problems with neural operators. However, challenges remain due to the heterogeneity of PDE datasets in equation types, which leads to high errors in mixed training. Additionally, dense pre-training models that scale parameters by increasing network width or depth incur significant inference costs. To tackle these challenges, we propose a novel Mixture-of-Experts Pre-training Operator Transformer (MoE-POT), a sparse-activated architecture that scales parameters efficiently while controlling inference costs. Specifically, our model adopts a layer-wise router-gating network to dynamically select 4 routed experts from 16 expert networks during inference, enabling the model to focus on equationspecific features. Meanwhile, we also integrate 2 shared experts, aiming to capture common properties of PDE and reduce redundancy among routed experts. The final output is computed as the weighted average of the results from all activated experts.

Molecular Relational Learning (MRL) is a rapidly growing field that focuses on understanding the interaction dynamics between molecules, which is crucial for applications ranging from catalyst engineering to drug discovery. Despite recent progress, ture of molecules, earlier MRL as obtaining approaches the are 3D limited interaction to using geometry only the remains 2D topological prohibiti strucvely expensive. This paper introduces a novel 3D geometric pre-training strategy for MRL (3DMRL) that incorporates a 3D virtual interaction environment, overcoming the the constructe limitations d of 3D costly virtual tradit interaction ional quantum environment, mechanical 3DMRL calculation trains 2D methods. MRL model With to learn the global and local 3D geometric information of molecular interaction. Extensive experiments on various tasks using real-world datasets, including out-ofdistribution and extrapolation scenarios, demonstrate the effectiveness of 3DMRL, sho publicly wing a up vailable to a 24.93% at https://github.com/

Despite substantial efforts in safety alignment, recent research indicates that Large Language Models (LLMs) remain highly susceptible to jailbreak attacks.