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Treatment Stitching with Schrödinger Bridge for Enhancing Offline Reinforcement Learning in Adaptive Treatment Strategies

arXiv.org Artificial Intelligence

Adaptive treatment strategies (ATS) are sequential decision-making processes that enable personalized care by dynamically adjusting treatment decisions in response to evolving patient symptoms. While reinforcement learning (RL) offers a promising approach for optimizing ATS, its conventional online trial-and-error learning mechanism is not permissible in clinical settings due to risks of harm to patients. Offline RL tackles this limitation by learning policies exclusively from historical treatment data, but its performance is often constrained by data scarcity-a pervasive challenge in clinical domains. To overcome this, we propose Treatment Stitching (TreatStitch), a novel data augmentation framework that generates clinically valid treatment trajectories by intelligently stitching segments from existing treatment data. Specifically, TreatStitch identifies similar intermediate patient states across different trajectories and stitches their respective segments. Even when intermediate states are too dissimilar to stitch directly, TreatStitch leverages the Schrödinger bridge method to generate smooth and energy-efficient bridging trajectories that connect dissimilar states. By augmenting these synthetic trajectories into the original dataset, offline RL can learn from a more diverse dataset, thereby improving its ability to optimize ATS. Extensive experiments across multiple treatment datasets demonstrate the effectiveness of TreatStitch in enhancing offline RL performance. Furthermore, we provide a theoretical justification showing that TreatStitch maintains clinical validity by avoiding out-of-distribution transitions.


Informed Bootstrap Augmentation Improves EEG Decoding

arXiv.org Artificial Intelligence

Electroencephalography (EEG) offers detailed access to neural dynamics but remains constrained by noise and trial-by-trial variability, limiting decoding performance in data-restricted or complex paradigms. Data augmentation is often employed to enhance feature representations, yet conventional uniform averaging overlooks differences in trial informativeness and can degrade representational quality. We introduce a weighted bootstrapping approach that prioritizes more reliable trials to generate higher-quality augmented samples. In a Sentence Evaluation paradigm, weights were computed from relative ERP differences and applied during probabilistic sampling and averaging. Across conditions, weighted bootstrapping improved decoding accuracy relative to unweighted (from 68.35% to 71.25% at best), demonstrating that emphasizing reliable trials strengthens representational quality. The results demonstrate that reliability-based augmentation yields more robust and discriminative EEG representations. The code is publicly available at https://github.com/lyricists/NeuroBootstrap.


Exploring AI in Steganography and Steganalysis: Trends, Clusters, and Sustainable Development Potential

arXiv.org Artificial Intelligence

Steganography and steganalysis are strongly related subjects of information security. Over the past decade, many powerful and efficient artificial intelligence (AI) - driven techniques have been designed and presented during research into steganography as well as steganalysis. This study presents a scientometric analysis of AI-driven steganography-based data hiding techniques using a thematic modelling approach. A total of 654 articles within the time span of 2017 to 2023 have been considered. Experimental evaluation of the study reveals that 69% of published articles are from Asian countries. The China is on top (TP:312), followed by India (TP-114). The study mainly identifies seven thematic clusters: steganographic image data hiding, deep image steganalysis, neural watermark robustness, linguistic steganography models, speech steganalysis algorithms, covert communication networks, and video steganography techniques. The proposed study also assesses the scope of AI-steganography under the purview of sustainable development goals (SDGs) to present the interdisciplinary reciprocity between them. It has been observed that only 18 of the 654 articles are aligned with one of the SDGs, which shows that limited studies conducted in alignment with SDG goals. SDG9 which is Industry, Innovation, and Infrastructure is leading among 18 SDGs mapped articles. To the top of our insight, this study is the unique one to present a scientometric study on AI-driven steganography-based data hiding techniques. In the context of descriptive statistics, the study breaks down the underlying causes of observed trends, including the influence of DL developments, trends in East Asia and maturity of foundational methods. The work also stresses upon the critical gaps in societal alignment, particularly the SDGs, ultimately working on unveiling the field's global impact on AI security challenges.


DCMM-Transformer: Degree-Corrected Mixed-Membership Attention for Medical Imaging

arXiv.org Artificial Intelligence

Medical images exhibit latent anatomical groupings, such as organs, tissues, and pathological regions, that standard Vision Transformers (ViTs) fail to exploit. While recent work like SBM-Transformer attempts to incorporate such structures through stochastic binary masking, they suffer from non-differentiability, training instability, and the inability to model complex community structure. We present DCMM-Transformer, a novel ViT architecture for medical image analysis that incorporates a Degree-Corrected Mixed-Membership (DCMM) model as an additive bias in self-attention. Unlike prior approaches that rely on multiplicative masking and binary sampling, our method introduces community structure and degree heterogeneity in a fully differentiable and interpretable manner. Comprehensive experiments across diverse medical imaging datasets, including brain, chest, breast, and ocular modalities, demonstrate the superior performance and generalizability of the proposed approach. Furthermore, the learned group structure and structured attention modulation substantially enhance interpretability by yielding attention maps that are anatomically meaningful and semantically coherent.


BackWeak: Backdooring Knowledge Distillation Simply with Weak Triggers and Fine-tuning

arXiv.org Artificial Intelligence

Knowledge Distillation (KD) is essential for compressing large models, yet relying on pre-trained "teacher" models downloaded from third-party repositories introduces serious security risks -- most notably backdoor attacks. Existing KD backdoor methods are typically complex and computationally intensive: they employ surrogate student models and simulated distillation to guarantee transferability, and they construct triggers in a way similar to universal adversarial perturbations (UAPs), which being not stealthy in magnitude, inherently exhibit strong adversarial behavior. This work questions whether such complexity is necessary and constructs stealthy "weak" triggers -- imperceptible perturbations that have negligible adversarial effect. We propose BackWeak, a simple, surrogate-free attack paradigm. BackWeak shows that a powerful backdoor can be implanted by simply fine-tuning a benign teacher with a weak trigger using a very small learning rate. We demonstrate that this delicate fine-tuning is sufficient to embed a backdoor that reliably transfers to diverse student architectures during a victim's standard distillation process, yielding high attack success rates. Extensive empirical evaluations on multiple datasets, model architectures, and KD methods show that BackWeak is efficient, simpler, and often more stealthy than previous elaborate approaches. This work calls on researchers studying KD backdoor attacks to pay particular attention to the trigger's stealthiness and its potential adversarial characteristics.


Preference Learning from Physics-Based Feedback: Tuning Language Models to Design BCC/B2 Superalloys

arXiv.org Artificial Intelligence

We apply preference learning to the task of language model-guided design of novel structural alloys. In contrast to prior work that focuses on generating stable inorganic crystals, our approach targets the synthesizeability of a specific structural class: BCC/B2 superalloys, an underexplored family of materials with potential applications in extreme environments. Using three open-weight models (LLaMA-3.1, Gemma-2, and OLMo-2), we demonstrate that language models can be optimized for multiple design objectives using a single, unified reward signal through Direct Preference Optimization (DPO). Unlike prior approaches that rely on heuristic or human-in-the-loop feedback (costly), our reward signal is derived from thermodynamic phase calculations, offering a scientifically grounded criterion for model tuning. To our knowledge, this is the first demonstration of preference-tuning a language model using physics-grounded feedback for structural alloy design. The resulting framework is general and extensible, providing a path forward for intelligent design-space exploration across a range of physical science domains.


SBAMP: Sampling Based Adaptive Motion Planning

arXiv.org Artificial Intelligence

Autonomous robotic systems must navigate complex, dynamic environments in real time, often facing unpredictable obstacles and rapidly changing conditions. Traditional sampling-based methods, such as RRT*, excel at generating collision-free paths but struggle to adapt to sudden changes without extensive replanning. Conversely, learning-based dynamical systems, such as the Stable Estimator of Dynamical Systems (SEDS), offer smooth, adaptive trajectory tracking but typically rely on pre-collected demonstration data, limiting their generalization to novel scenarios. This paper introduces Sampling-Based Adaptive Motion Planning (SBAMP), a novel framework that overcomes these limitations by integrating RRT* for global path planning with a SEDS-based local controller for continuous, adaptive trajectory adjustment. Our approach requires no pre-trained datasets and ensures smooth transitions between planned waypoints, maintaining stability through Lyapunov-based guarantees. We validate SBAMP in both simulated environments and real hardware using the RoboRacer platform, demonstrating superior performance in dynamic obstacle scenarios, rapid recovery from perturbations, and robust handling of sharp turns. Experimental results highlight SBAMP's ability to adapt in real time without sacrificing global path optimality, providing a scalable solution for dynamic, unstructured environments.


Enhancing Road Safety Through Multi-Camera Image Segmentation with Post-Encroachment Time Analysis

arXiv.org Artificial Intelligence

Abstract--Traffic safety analysis at signalized intersections is vital for reducing vehicle and pedestrian collisions, yet traditional crash-based studies are limited by data sparsity and latency. This paper presents a novel multi-camera computer vision framework for real-time safety assessment through Post-Encroachment Time (PET) computation, demonstrated at the intersection of H Street and Broadway in Chula Vista, California. Four synchronized cameras provide continuous visual coverage, with each frame processed on NVIDIA Jetson AGX Xavier devices using YOLOv11 segmentation for vehicle detection. Detected vehicle polygons are transformed into a unified bird's-eye map using homography matrices, enabling alignment across overlapping camera views. A novel pixel-level PET algorithm measures vehicle position without reliance on fixed cells, allowing fine-grained hazard visualization via dynamic heatmaps, accurate to 3.3 sq-cm. Timestamped vehicle and PET data is stored in an SQL database for long-term monitoring. Results over various time intervals demonstrate the framework's ability to identify high-risk regions with sub-second precision and real-time throughput on edge devices, producing data for an 800 800 pixel logarithmic heatmap at an average of 2.68 FPS. A. Context and Motivation Traffic safety at signalized intersections remains a critical concern in urban planning, as intersections present challenges of high vehicle conflict and elevated accident risk. Large and open intersections, in particular, present challenges due to increased vehicle maneuvering space, multiple conflict points, and reduced natural traffic control, which leads to higher speeds and greater uncertainty in driver behavior.


Adaptive Diagnostic Reasoning Framework for Pathology with Multimodal Large Language Models

arXiv.org Artificial Intelligence

AI tools in pathology have improved screening throughput, standardized quantification, and revealed prognostic patterns that inform treatment. However, adoption remains limited because most systems still lack the human-readable reasoning needed to audit decisions and prevent errors. We present RECAP-PATH, an interpretable framework that establishes a self-learning paradigm, shifting off-the-shelf multimodal large language models from passive pattern recognition to evidence-linked diagnostic reasoning. At its core is a two-phase learning process that autonomously derives diagnostic criteria: diversification expands pathology-style explanations, while optimization refines them for accuracy. This self-learning approach requires only small labeled sets and no white-box access or weight updates to generate cancer diagnoses. Evaluated on breast and prostate datasets, RECAP-PATH produced rationales aligned with expert assessment and delivered substantial gains in diagnostic accuracy over baselines. By uniting visual understanding with reasoning, RECAP-PATH provides clinically trustworthy AI and demonstrates a generalizable path toward evidence-linked interpretation.


Uncertainty-Guided Selective Adaptation Enables Cross-Platform Predictive Fluorescence Microscopy

arXiv.org Artificial Intelligence

Deep learning is transforming microscopy, yet models often fail when applied to images from new instruments or acquisition settings. Conventional adversarial domain adaptation (ADDA) retrains entire networks, often disrupting learned semantic representations. Here, we overturn this paradigm by showing that adapting only the earliest convolutional layers, while freezing deeper layers, yields reliable transfer. Building on this principle, we introduce Subnetwork Image Translation ADDA with automatic depth selection (SIT-ADDA-Auto), a self-configuring framework that integrates shallow-layer adversarial alignment with predictive uncertainty to automatically select adaptation depth without target labels. We demonstrate robustness via multi-metric evaluation, blinded expert assessment, and uncertainty-depth ablations. Across exposure and illumination shifts, cross-instrument transfer, and multiple stains, SIT-ADDA improves reconstruction and downstream segmentation over full-encoder adaptation and non-adversarial baselines, with reduced drift of semantic features. Our results provide a design rule for label-free adaptation in microscopy and a recipe for field settings; the code is publicly available.