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Evaluating the Ability of Large Language Models to Identify Adherence to CONSORT Reporting Guidelines in Randomized Controlled Trials: A Methodological Evaluation Study
He, Zhichao, Bian, Mouxiao, Zhu, Jianhong, Chen, Jiayuan, Wang, Yunqiu, Zhao, Wenxia, Li, Tianbin, Han, Bing, Xu, Jie, Wu, Junyan
The Consolidated Standards of Reporting Trials statement is the global benchmark for transparent and high-quality reporting of randomized controlled trials. Manual verification of CONSORT adherence is a laborious, time-intensive process that constitutes a significant bottleneck in peer review and evidence synthesis. This study aimed to systematically evaluate the accuracy and reliability of contemporary LLMs in identifying the adherence of published RCTs to the CONSORT 2010 statement under a zero-shot setting. We constructed a golden standard dataset of 150 published RCTs spanning diverse medical specialties. The primary outcome was the macro-averaged F1-score for the three-class classification task, supplemented by item-wise performance metrics and qualitative error analysis. Overall model performance was modest. The top-performing models, Gemini-2.5-Flash and DeepSeek-R1, achieved nearly identical macro F1 scores of 0.634 and Cohen's Kappa coefficients of 0.280 and 0.282, respectively, indicating only fair agreement with expert consensus. A striking performance disparity was observed across classes: while most models could identify compliant items with high accuracy (F1 score > 0.850), they struggled profoundly with identifying non-compliant and not applicable items, where F1 scores rarely exceeded 0.400. Notably, some high-profile models like GPT-4o underperformed, achieving a macro F1-score of only 0.521. LLMs show potential as preliminary screening assistants for CONSORT checks, capably identifying well-reported items. However, their current inability to reliably detect reporting omissions or methodological flaws makes them unsuitable for replacing human expertise in the critical appraisal of trial quality.
Transformer-Based Scalable Multi-Agent Reinforcement Learning for Networked Systems with Long-Range Interactions
Sinha, Vidur, Ustaomeroglu, Muhammed, Qu, Guannan
Multi-agent reinforcement learning (MARL) has shown promise for large-scale network control, yet existing methods face two major limitations. First, they typically rely on assumptions leading to decay properties of local agent interactions, limiting their ability to capture long-range dependencies such as cascading power failures or epidemic outbreaks. Second, most approaches lack generalizability across network topologies, requiring retraining when applied to new graphs. We introduce STACCA (Shared Transformer Actor-Critic with Counterfactual Advantage), a unified transformer-based MARL framework that addresses both challenges. STACCA employs a centralized Graph Transformer Critic to model long-range dependencies and provide system-level feedback, while its shared Graph Transformer Actor learns a generalizable policy capable of adapting across diverse network structures. Further, to improve credit assignment during training, STACCA integrates a novel counterfactual advantage estimator that is compatible with state-value critic estimates. We evaluate STACCA on epidemic containment and rumor-spreading network control tasks, demonstrating improved performance, network generalization, and scalability. These results highlight the potential of transformer-based MARL architectures to achieve scalable and generalizable control in large-scale networked systems.
Real-time prediction of breast cancer sites using deformation-aware graph neural network
Lee, Kyunghyun, Shin, Yong-Min, Shin, Minwoo, Kim, Jihun, Lim, Sunghwan, Shin, Won-Yong, Yoon, Kyungho
Early diagnosis of breast cancer is crucial, enabling the establishment of appropriate treatment plans and markedly enhancing patient prognosis. While direct magnetic resonance imaging-guided biopsy demonstrates promising performance in detecting cancer lesions, its practical application is limited by prolonged procedure times and high costs. To overcome these issues, an indirect MRI-guided biopsy that allows the procedure to be performed outside of the MRI room has been proposed, but it still faces challenges in creating an accurate real-time deformable breast model. In our study, we tackled this issue by developing a graph neural network (GNN)-based model capable of accurately predicting deformed breast cancer sites in real time during biopsy procedures. An individual-specific finite element (FE) model was developed by incorporating magnetic resonance (MR) image-derived structural information of the breast and tumor to simulate deformation behaviors. A GNN model was then employed, designed to process surface displacement and distance-based graph data, enabling accurate prediction of overall tissue displacement, including the deformation of the tumor region. The model was validated using phantom and real patient datasets, achieving an accuracy within 0.2 millimeters (mm) for cancer node displacement (RMSE) and a dice similarity coefficient (DSC) of 0.977 for spatial overlap with actual cancerous regions. Additionally, the model enabled real-time inference and achieved a speed-up of over 4,000 times in computational cost compared to conventional FE simulations. The proposed deformation-aware GNN model offers a promising solution for real-time tumor displacement prediction in breast biopsy, with high accuracy and real-time capability. Its integration with clinical procedures could significantly enhance the precision and efficiency of breast cancer diagnosis.
A Smart-Glasses for Emergency Medical Services via Multimodal Multitask Learning
Jin, Liuyi, Gunawardena, Pasan, Haroon, Amran, Wang, Runzhi, Lee, Sangwoo, Stoleru, Radu, Middleton, Michael, Huo, Zepeng, Kim, Jeeeun, Moats, Jason
Emergency Medical Technicians (EMTs) operate in high-pressure environments, making rapid, life-critical decisions under heavy cognitive and operational loads. We present EMSGlass, a smart-glasses system powered by EMSNet, the first multimodal multitask model for Emergency Medical Services (EMS), and EMSServe, a low-latency multimodal serving framework tailored to EMS scenarios. EMSNet integrates text, vital signs, and scene images to construct a unified real-time understanding of EMS incidents. Trained on real-world multimodal EMS datasets, EMSNet simultaneously supports up to five critical EMS tasks with superior accuracy compared to state-of-the-art unimodal baselines. Built on top of PyTorch, EMSServe introduces a modality-aware model splitter and a feature caching mechanism, achieving adaptive and efficient inference across heterogeneous hardware while addressing the challenge of asynchronous modality arrival in the field. By optimizing multimodal inference execution in EMS scenarios, EMSServe achieves 1.9x -- 11.7x speedup over direct PyTorch multimodal inference. A user study evaluation with six professional EMTs demonstrates that EMSGlass enhances real-time situational awareness, decision-making speed, and operational efficiency through intuitive on-glass interaction. In addition, qualitative insights from the user study provide actionable directions for extending EMSGlass toward next-generation AI-enabled EMS systems, bridging multimodal intelligence with real-world emergency response workflows.
Self-Adaptive Graph Mixture of Models
Meena, Mohit, Punjabi, Yash, A, Abhishek, Sharma, Vishal, Chandran, Mahesh
Graph Neural Networks (GNNs) have emerged as powerful tools for learning over graph-structured data, yet recent studies have shown that their performance gains are beginning to plateau. In many cases, well-established models such as GCN and GA T, when appropriately tuned, can match or even exceed the performance of more complex, state-of-the-art architectures. This trend highlights a key limitation in the current landscape: the difficulty of selecting the most suitable model for a given graph task or dataset. To address this, we propose Self-Adaptive Graph Mixture of Models (SAGMM), a modular and practical framework that learns to automatically select and combine the most appropriate GNN models from a diverse pool of architectures. Unlike prior mixture-of-experts approaches that rely on variations of a single base model, SAGMM leverages architectural diversity and a topology-aware attention gating mechanism to adaptively assign experts to each node based on the structure of the input graph. To improve efficiency, SAGMM includes a pruning mechanism that reduces the number of active experts during training and inference without compromising performance. We also explore a training-efficient variant in which expert models are pretrained and frozen, and only the gating and task-specific layers are trained. We evaluate SAGMM on 16 benchmark datasets covering node classification, graph classification, regression, and link prediction tasks, and demonstrate that it consistently outperforms or matches leading GNN baselines and prior mixture-based methods, offering a robust and adaptive solution for real-world graph learning. Code is released at https://github.com/ast-fri/SAGMM.
Learning from the Undesirable: Robust Adaptation of Language Models without Forgetting
Nam, Yunhun, Kim, Jaehyung, Jeong, Jongheon
Language models (LMs) are often adapted through supervised fine-tuning (SFT) to specialize their capabilities for downstream tasks. However, in typical scenarios where the fine-tuning data is limited, e.g., compared to pre-training, SFT can lead LMs to overfit, causing them to rely on spurious patterns within the target task or to compromise other broadly useful capabilities as a side effect of narrow specialization. In this paper, we propose Learning-from-the-Undesirable (LfU), a simple yet effective regularization scheme for SFT to mitigate overfitting issues when fine-tuning LMs with limited data. Specifically, we aim to regularize the fine-tuning process to favor solutions that are resilient to "undesirable" model updates, e.g., gradient ascent steps that steer the model toward undesirable behaviors. To this end, we propose a novel form of consistency regularization that directly aligns internal representations of the model with those after an undesirable update. By leveraging representation-level data augmentation through undesirable updates, LfU effectively promotes generalization under limited data. Our experiments on diverse LM downstream tasks show that LfU serves as an effective prior that enhances adaptability while preserving pretrained knowledge. For example, our LM from LfU achieves a 16.8% average improvement on math tasks compared to vanilla SFT on the same dataset, where the latter even leads to degraded performance on those tasks. Furthermore, LfU exhibits improved robustness to prompt variations, e.g., yielding a 92.1% lower standard deviation in output performances compared to SFT, highlighting its versatile effects.
Unidirectional-Road-Network-Based Global Path Planning for Cleaning Robots in Semi-Structured Environments
Practical global path planning is critical for commercializing cleaning robots working in semi-structured environments. In the literature, global path planning methods for free space usually focus on path length and neglect the traffic rule constraints of the environments, which leads to high-frequency re-planning and increases collision risks. In contrast, those for structured environments are developed mainly by strictly complying with the road network representing the traffic rule constraints, which may result in an overlong path that hinders the overall navigation efficiency. This article proposes a general and systematic approach to improve global path planning performance in semi-structured environments. A unidirectional road network is built to represent the traffic constraints in semi-structured environments and a hybrid strategy is proposed to achieve a guaranteed planning result.Cutting across the road at the starting and the goal points are allowed to achieve a shorter path. Especially, a two-layer potential map is proposed to achieve a guaranteed performance when the starting and the goal points are in complex intersections. Comparative experiments are carried out to validate the effectiveness of the proposed method. Quantitative experimental results show that, compared with the state-of-art, the proposed method guarantees a much better balance between path length and the consistency with the road network.
DiffPixelFormer: Differential Pixel-Aware Transformer for RGB-D Indoor Scene Segmentation
Gong, Yan, Lu, Jianli, Gao, Yongsheng, Zhao, Jie, Zhang, Xiaojuan, Rahardja, Susanto
Indoor semantic segmentation is fundamental to computer vision and robotics, supporting applications such as autonomous navigation, augmented reality, and smart environments. Although RGB-D fusion leverages complementary appearance and geometric cues, existing methods often depend on computationally intensive cross-attention mechanisms and insufficiently model intra- and inter-modal feature relationships, resulting in imprecise feature alignment and limited discriminative representation. To address these challenges, we propose DiffPixelFormer, a differential pixel-aware Transformer for RGB-D indoor scene segmentation that simultaneously enhances intra-modal representations and models inter-modal interactions. At its core, the Intra-Inter Modal Interaction Block (IIMIB) captures intra-modal long-range dependencies via self-attention and models inter-modal interactions with the Differential-Shared Inter-Modal (DSIM) module to disentangle modality-specific and shared cues, enabling fine-grained, pixel-level cross-modal alignment. Furthermore, a dynamic fusion strategy balances modality contributions and fully exploits RGB-D information according to scene characteristics. Extensive experiments on the SUN RGB-D and NYUDv2 benchmarks demonstrate that DiffPixelFormer-L achieves mIoU scores of 54.28% and 59.95%, outperforming DFormer-L by 1.78% and 2.75%, respectively. Code is available at https://github.com/gongyan1/DiffPixelFormer.
Bi-View Embedding Fusion: A Hybrid Learning Approach for Knowledge Graph's Nodes Classification Addressing Problems with Limited Data
Napoli, Rosario, Lonia, Giovanni, Celesti, Antonio, Villari, Massimo, Fazio, Maria
Traditional Machine Learning (ML) methods require large amounts of data to perform well, limiting their applicability in sparse or incomplete scenarios and forcing the usage of additional synthetic data to improve the model training. To overcome this challenge, the research community is looking more and more at Graph Machine Learning (GML) as it offers a powerful alternative by using relationships within data. However, this method also faces limitations, particularly when dealing with Knowledge Graphs (KGs), which can hide huge information due to their semantic nature. This study introduces Bi-View, a novel hybrid approach that increases the informative content of node features in KGs to generate enhanced Graph Embeddings (GEs) that are used to improve GML models without relying on additional synthetic data. The proposed work combines two complementary GE techniques: Node2Vec, which captures structural patterns through unsupervised random walks, and GraphSAGE, which aggregates neighbourhood information in a supervised way. Node2Vec embeddings are first computed to represent the graph topology, and node features are then enriched with centrality-based metrics, which are used as input for the GraphSAGE model. Moreover, a fusion layer combines the original Node2Vec embeddings with the GraphSAGE-influenced representations, resulting in a dual-perspective embedding space. Such a fusion captures both topological and semantic properties of the graph, enabling the model to exploit informative features that may exist in the dataset but that are not explicitly represented. Our approach improves downstream task performance, especially in scenarios with poor initial features, giving the basis for more accurate and precise KG-enanched GML models.
AA-Omniscience: Evaluating Cross-Domain Knowledge Reliability in Large Language Models
Jackson, Declan, Keating, William, Cameron, George, Hill-Smith, Micah
We introduce AA-Omniscience, a benchmark designed to measure both factual recall and knowledge calibration across 6,000 questions. Questions are derived from authoritative academic and industry sources, and cover 42 economically relevant topics within six different domains. The evaluation measures a model's Omniscience Index, a bounded metric (-100 to 100) measuring factual recall that jointly penalizes hallucinations and rewards abstention when uncertain, with 0 equating to a model that answers questions correctly as much as it does incorrectly. Among evaluated models, Claude 4.1 Opus attains the highest score (4.8), making it one of only three models to score above zero. These results reveal persistent factuality and calibration weaknesses across frontier models. Performance also varies by domain, with the models from three different research labs leading across the six domains. This performance variability suggests models should be chosen according to the demands of the use case rather than general performance for tasks where knowledge is important.