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Cinematic Mindscapes: High-quality Video Reconstruction from Brain Activity

Neural Information Processing Systems

Reconstructing human vision from brain activities has been an appealing task that helps to understand our cognitive process. Even though recent research has seen great success in reconstructing static images from non-invasive brain recordings, work on recovering continuous visual experiences in the form of videos is limited. In this work, we propose Mind-Video that learns spatiotemporal information from continuous fMRI data of the cerebral cortex progressively through masked brain modeling, multimodal contrastive learning with spatiotemporal attention, and co-training with an augmented Stable Diffusion model that incorporates network temporal inflation. We show that high-quality videos of arbitrary frame rates can be reconstructed with Mind-Video using adversarial guidance. The recovered videos were evaluated with various semantic and pixel-level metrics. We achieved an average accuracy of 85% in semantic classification tasks and 0.19 in structural similarity index (SSIM), outperforming the previous state-of-the-art by 45%. We also show that our model is biologically plausible and interpretable, reflecting established physiological processes.


Better Transfer Learning with Inferred Successor Maps

Neural Information Processing Systems

Humans and animals show remarkable flexibility in adjusting their behaviour when their goals, or rewards in the environment change. While such flexibility is a hallmark of intelligent behaviour, these multi-task scenarios remain an important challenge for machine learning algorithms and neurobiological models alike. We investigated two approaches that could enable this flexibility: factorized representations, which abstract away general aspects of a task from those prone to change, and nonparametric, memory-based approaches, which can provide a principled way of using similarity to past experiences to guide current behaviour. In particular, we combine the successor representation (SR), that factors the value of actions into expected outcomes and corresponding rewards, with evaluating task similarity through clustering the space of rewards. The proposed algorithm inverts a generative model over tasks, and dynamically samples from a flexible number of distinct SR maps while accumulating evidence about the current task context through amortized inference. It improves SR's transfer capabilities and outperforms competing algorithms and baselines in settings with both known and unsignalled rewards changes. Further, as a neurobiological model of spatial coding in the hippocampus, it explains important signatures of this representation, such as the flickering behaviour of hippocampal maps, and trajectory-dependent place cells (so-called splitter cells) and their dynamics. We thus provide a novel algorithmic approach for multi-task learning, as well as a common normative framework that links together these different characteristics of the brain's spatial representation.


Dueling Bandits with Adversarial Sleeping

Neural Information Processing Systems

We introduce the problem of sleeping dueling bandits with stochastic preferences and adversarial availabilities (DB-SPAA). In almost all dueling bandit applications, the decision space often changes over time; eg, retail store management, online shopping, restaurant recommendation, search engine optimization, etc. Surprisingly, this `sleeping aspect' of dueling bandits has never been studied in the literature. Like dueling bandits, the goal is to compete with the best arm by sequentially querying the preference feedback of item pairs. The non-triviality however results due to the non-stationary item spaces that allow any arbitrary subsets items to go unavailable every round. The goal is to find an optimal `no-regret policy that can identify the best available item at each round, as opposed to the standard `fixed best-arm regret objective' of dueling bandits. We first derive an instance-specific lower bound for DB-SPAA $\Omega( \sum_{i =1}^{K-1}\sum_{j=i+1}^K \frac{\log T}{\Delta(i,j)})$, where $K$ is the number of items and $\Delta(i,j)$ is the gap between items $i$ and $j$. This indicates that the sleeping problem with preference feedback is inherently more difficult than that for classical multi-armed bandits (MAB). We then propose two algorithms, with near optimal regret guarantees. Our results are corroborated empirically.


Dynamic COVID risk assessment accounting for community virus exposure from a spatial-temporal transmission model

Neural Information Processing Systems

COVID-19 pandemic has caused unprecedented negative impacts on our society, including further exposing inequity and disparity in public health. To study the impact of socioeconomic factors on COVID transmission, we first propose a spatial-temporal model to examine the socioeconomic heterogeneity and spatial correlation of COVID-19 transmission at the community level. Second, to assess the individual risk of severe COVID-19 outcomes after a positive diagnosis, we propose a dynamic, varying-coefficient model that integrates individual-level risk factors from electronic health records (EHRs) with community-level risk factors. The underlying neighborhood prevalence of infections (both symptomatic and pre-symptomatic) predicted from the previous spatial-temporal model is included in the individual risk assessment so as to better capture the background risk of virus exposure for each individual. We design a weighting scheme to mitigate multiple selection biases inherited in EHRs of COVID patients. We analyze COVID transmission data in New York City (NYC, the epicenter of the first surge in the United States) and EHRs from NYC hospitals, where time-varying effects of community risk factors and significant interactions between individual-and community-level risk factors are detected. By examining the socioeconomic disparity of infection risks and interaction among the risk factors, our methods can assist public health decision-making and facilitate better clinical management of COVID patients.


Reconstructing the Mind's Eye: fMRI-to-Image with Contrastive Learning and Diffusion Priors

Neural Information Processing Systems

We present MindEye, a novel fMRI-to-image approach to retrieve and reconstruct viewed images from brain activity. Our model comprises two parallel submodules that are specialized for retrieval (using contrastive learning) and reconstruction (using a diffusion prior). MindEye can map fMRI brain activity to any high dimensional multimodal latent space, like CLIP image space, enabling image reconstruction using generative models that accept embeddings from this latent space. We comprehensively compare our approach with other existing methods, using both qualitative side-by-side comparisons and quantitative evaluations, and show that MindEye achieves state-of-the-art performance in both reconstruction and retrieval tasks. In particular, MindEye can retrieve the exact original image even among highly similar candidates indicating that its brain embeddings retain fine-grained image-specific information. This allows us to accurately retrieve images even from large-scale databases like LAION-5B. We demonstrate through ablations that MindEye's performance improvements over previous methods result from specialized submodules for retrieval and reconstruction, improved training techniques, and training models with orders of magnitude more parameters. Furthermore, we show that MindEye can better preserve low-level image features in the reconstructions by using img2img, with outputs from a separate autoencoder. All code is available on GitHub.


Improving Self-supervised Learning with Automated Unsupervised Outlier Arbitration

Neural Information Processing Systems

Our work reveals a structured shortcoming of the existing mainstream self-supervised learning methods. Whereas self-supervised learning frameworks usually take the prevailing perfect instance level invariance hypothesis for granted, we carefully investigate the pitfalls behind. Particularly, we argue that the existing augmentation pipeline for generating multiple positive views naturally introduces out-of-distribution (OOD) samples that undermine the learning of the downstream tasks. Generating diverse positive augmentations on the input does not always pay off in benefiting downstream tasks. To overcome this inherent deficiency, we introduce a lightweight latent variable model UOTA, targeting the view sampling issue for self-supervised learning. UOTA adaptively searches for the most important sampling region to produce views, and provides viable choice for outlier-robust self-supervised learning approaches.


Efficient Adversarial Attacks on Online Multi-agent Reinforcement Learning

Neural Information Processing Systems

Due to the broad range of applications of multi-agent reinforcement learning (MARL), understanding the effects of adversarial attacks against MARL model is essential for the safe applications of this model. Motivated by this, we investigate the impact of adversarial attacks on MARL. In the considered setup, there is an exogenous attacker who is able to modify the rewards before the agents receive them or manipulate the actions before the environment receives them. The attacker aims to guide each agent into a target policy or maximize the cumulative rewards under some specific reward function chosen by the attacker, while minimizing the amount of the manipulation on feedback and action. We first show the limitations of the action poisoning only attacks and the reward poisoning only attacks. We then introduce a mixed attack strategy with both the action poisoning and reward poisoning. We show that the mixed attack strategy can efficiently attack MARL agents even if the attacker has no prior information about the underlying environment and the agents' algorithms.


Estimating graphical models for count data with applications to single-cell gene network

Neural Information Processing Systems

Graphical models such as Gaussian graphical models have been widely applied for direct interaction inference in many different areas. In many modern applications, such as single-cell RNA sequencing (scRNA-seq) studies, the observed data are counts and often contain many small counts. Traditional graphical models for continuous data are inappropriate for network inference of count data. We consider the Poisson log-normal (PLN) graphical model for count data and the precision matrix of the latent normal distribution represents the network. We propose a two-step method PLNet to estimate the precision matrix. PLNet first estimates the latent covariance matrix using the maximum marginal likelihood estimator (MMLE) and then estimates the precision matrix by minimizing the lasso-penalized D-trace loss function. We establish the convergence rate of the MMLE of the covariance matrix and further establish the convergence rate and the sign consistency of the proposed PLNet estimator of the precision matrix in the high dimensional setting. Importantly, although the PLN model is not sub-Gaussian, we show that the PLNet estimator is consistent even if the model dimension goes to infinity exponentially as the sample size increases. The performance of PLNet is evaluated and compared with available methods using simulation and gene regulatory network analysis of real scRNA-seq data.


In Differential Privacy, There is Truth: on Vote-Histogram Leakage in Ensemble Private Learning

Neural Information Processing Systems

When learning from sensitive data, care must be taken to ensure that training algorithms address privacy concerns. The canonical Private Aggregation of Teacher Ensembles, or PATE, computes output labels by aggregating the predictions of a (possibly distributed) collection of teacher models via a voting mechanism. The mechanism adds noise to attain a differential privacy guarantee with respect to the teachers' training data. In this work, we observe that this use of noise, which makes PATE predictions stochastic, enables new forms of leakage of sensitive information. For a given input, our adversary exploits this stochasticity to extract high-fidelity histograms of the votes submitted by the underlying teachers. From these histograms, the adversary can learn sensitive attributes of the input such as race, gender, or age. Although this attack does not directly violate the differential privacy guarantee, it clearly violates privacy norms and expectations, and would not be possible $\textit{at all}$ without the noise inserted to obtain differential privacy. In fact, counter-intuitively, the attack $\textbf{becomes easier as we add more noise}$ to provide stronger differential privacy. We hope this encourages future work to consider privacy holistically rather than treat differential privacy as a panacea.


Modeling Human Visual Motion Processing with Trainable Motion Energy Sensing and a Self-attention Network

Neural Information Processing Systems

Visual motion processing is essential for humans to perceive and interact with dynamic environments. Despite extensive research in cognitive neuroscience, image-computable models that can extract informative motion flow from natural scenes in a manner consistent with human visual processing have yet to be established. Meanwhile, recent advancements in computer vision (CV), propelled by deep learning, have led to significant progress in optical flow estimation, a task closely related to motion perception. Here we propose an image-computable model of human motion perception by bridging the gap between biological and CV models. Specifically, we introduce a novel two-stages approach that combines trainable motion energy sensing with a recurrent self-attention network for adaptive motion integration and segregation.