Cross-device federated learning is an emerging machine learning (ML) paradigm where a large population of devices collectively train an ML model while the data remains on the devices.This research field has a unique set of practical challenges, and to systematically make advances, new datasets curated to be compatible with this paradigm are needed.Existing federated learning benchmarks in the image domain do not accurately capture the scale and heterogeneity of many real-world use cases. We introduce FLAIR, a challenging large-scale annotated image dataset for multi-label classification suitable for federated learning.FLAIR has 429,078 images from 51,414 Flickr users and captures many of the intricacies typically encountered in federated learning, such as heterogeneous user data and a long-tailed label distribution.We implement multiple baselines in different learning setups for different tasks on this dataset. We believe FLAIR can serve as a challenging benchmark for advancing the state-of-the art in federated learning.Dataset access and the code for the benchmark are available at https://github.com/apple/ml-flair.

Recently cloud-based graph convolutional network (GCN) has demonstrated great success and potential in many privacy-sensitive applications such as personal healthcare and financial systems. Despite its high inference accuracy and performance on the cloud, maintaining data privacy in GCN inference, which is of paramount importance to these practical applications, remains largely unexplored. In this paper, we take an initial attempt towards this and develop CryptoGCN--a homomorphic encryption (HE) based GCN inference framework. A key to the success of our approach is to reduce the tremendous computational overhead for HE operations, which can be orders of magnitude higher than its counterparts in the plaintext space. To this end, we develop a solution that can effectively take advantage of the sparsity of matrix operations in GCN inference to significantly reduce the encrypted computational overhead. Specifically, we propose a novel Adjacency Matrix-Aware (AMA) data formatting method along with the AMA assisted patterned sparse matrix partitioning, to exploit the complex graph structure and perform efficient matrix-matrix multiplication in HE computation. In this way, the number of HE operations can be significantly reduced. We also develop a co-optimization framework that can explore the trade-offs among the accuracy, security level, and computational overhead by judicious pruning and polynomial approximation of activation modules in GCNs. Based on the NTU-XVIEW skeleton joint dataset, i.e., the largest dataset evaluated homomorphically by far as we are aware of, our experimental results demonstrate that CryptoGCN outperforms state-of-the-art solutions in terms of the latency and number of homomorphic operations, i.e., achieving as much as a 3.10$\times$ speedup on latency and reduces the total Homomorphic Operation Count (HOC) by 77.4\% with a small accuracy loss of 1-1.5$\%$.

Recent breakthroughs in AI for multi-agent games like Go, Poker, and Dota, have seen great strides in recent years. Yet none of these games address the real-life challenge of cooperation in the presence of unknown and uncertain teammates. This challenge is a key game mechanism in hidden role games. Here we develop the DeepRole algorithm, a multi-agent reinforcement learning agent that we test on The Resistance: Avalon, the most popular hidden role game. DeepRole combines counterfactual regret minimization (CFR) with deep value networks trained through self-play.

This paper develops a prediction-based prescriptive model for optimal decision making that (i) predicts the outcome under each action using a robust nonlinear model, and (ii) adopts a randomized prescriptive policy determined by the predicted outcomes. The predictive model combines a new regularized regression technique, which was developed using Distributionally Robust Optimization (DRO) with an ambiguity set constructed from the Wasserstein metric, with the K-Nearest Neighbors (K-NN) regression, which helps to capture the nonlinearity embedded in the data. We show theoretical results that guarantee the out-of-sample performance of the predictive model, and prove the optimality of the randomized policy in terms of the expected true future outcome. We demonstrate the proposed methodology on a hypertension dataset, showing that our prescribed treatment leads to a larger reduction in the systolic blood pressure compared to a series of alternatives. A clinically meaningful threshold level used to activate the randomized policy is also derived under a sub-Gaussian assumption on the predicted outcome.

Text-guided image editing is widely needed in daily life, ranging from personal use to professional applications such as Photoshop.However, existing methods are either zero-shot or trained on an automatically synthesized dataset, which contains a high volume of noise.Thus, they still require lots of manual tuning to produce desirable outcomes in practice.To address this issue, we introduce MagicBrush, the first large-scale, manually annotated dataset for instruction-guided real image editing that covers diverse scenarios: single-turn, multi-turn, mask-provided, and mask-free editing.MagicBrush comprises over 10K manually annotated triplets (source image, instruction, target image), which supports trainining large-scale text-guided image editing models.We fine-tune InstructPix2Pix on MagicBrush and show that the new model can produce much better images according to human evaluation.We further conduct extensive experiments to evaluate current image editing baselines from multiple dimensions including quantitative, qualitative, and human evaluations.The results reveal the challenging nature of our dataset and the gap between current baselines and real-world editing needs.

In Onyx Tempest, I wanted to capture the intensity of a Friesian skidding into a sharp turn. The backlit dust, flying mane, and sudden shift in momentum revealed his power and control. I framed the moment to emphasize energy, contrast, and the precision of the movement. Breakthroughs, discoveries, and DIY tips sent every weekday. The reFocus Awards has announced the stunning winners of the 2025 Photographers of the Year at the World Photo Annual .

Correctly capturing intraoperative brain shift in image-guided neurosurgical procedures is a critical task for aligning preoperative data with intraoperative geometry for ensuring accurate surgical navigation. While the finite element method (FEM) is a proven technique to effectively approximate soft tissue deformation through biomechanical formulations, their degree of success boils down to a trade-off between accuracy and speed. To circumvent this problem, the most recent works in this domain have proposed leveraging data-driven models obtained by training various machine learning algorithms---e.g., random forests, artificial neural networks (ANNs)---with the results of finite element analysis (FEA) to speed up tissue deformation approximations by prediction. These methods, however, do not account for the structure of the finite element (FE) mesh during training that provides information on node connectivities as well as the distance between them, which can aid with approximating tissue deformation based on the proximity of force load points with the rest of the mesh nodes. Therefore, this work proposes a novel framework, PhysGNN, a data-driven model that approximates the solution of the FEM by leveraging graph neural networks (GNNs), which are capable of accounting for the mesh structural information and inductive learning over unstructured grids and complex topological structures. Empirically, we demonstrate that the proposed architecture, PhysGNN, promises accurate and fast soft tissue deformation approximations, and is competitive with the state-of-the-art (SOTA) algorithms while promising enhanced computational feasibility, therefore suitable for neurosurgical settings.

Therapeutic antibodies are an essential and rapidly flourishing drug modality. The binding specificity between antibodies and antigens is decided by complementarity-determining regions (CDRs) at the tips of these Y-shaped proteins. In this paper, we propose a \textbf{h}ierarchical \textbf{t}raining \textbf{p}aradigm (HTP) for the antibody sequence-structure co-design. HTP consists of four levels of training stages, each corresponding to a specific protein modality within a particular protein domain. Through carefully crafted tasks in different stages, HTP seamlessly and effectively integrates geometric graph neural networks (GNNs) with large-scale protein language models to excavate evolutionary information from not only geometric structures but also vast antibody and non-antibody sequence databases, which determines ligand binding pose and strength. Empirical experiments show HTP sets the new state-of-the-art performance in the co-design problem as well as the fix-backbone design. Our research offers a hopeful path to unleash the potential of deep generative architectures and seeks to illuminate the way forward for the antibody sequence and structure co-design challenge.

Visual commonsense reasoning (VCR) has been introduced to boost research of cognition-level visual understanding, i.e., a thorough understanding of correlated details of the scene plus an inference with related commonsense knowledge. Recent studies on neuroscience have suggested that brain function or cognition can be described as a global and dynamic integration of local neuronal connectivity, which is context-sensitive to specific cognition tasks. Inspired by this idea, towards VCR, we propose a connective cognition network (CCN) to dynamically reorganize the visual neuron connectivity that is contextualized by the meaning of questions and answers. Concretely, we first develop visual neuron connectivity to fully model correlations of visual content. Then, a contextualization process is introduced to fuse the sentence representation with that of visual neurons. Finally, based on the output of contextualized connectivity, we propose directional connectivity to infer answers or rationales. Experimental results on the VCR dataset demonstrate the effectiveness of our method. Particularly, in $Q \to AR$ mode, our method is around 4\% higher than the state-of-the-art method.

The prompt-based learning paradigm has gained much research attention recently. It has achieved state-of-the-art performance on several NLP tasks, especially in the few-shot scenarios. While steering the downstream tasks, few works have been reported to investigate the security problems of the prompt-based models. In this paper, we conduct the first study on the vulnerability of the continuous prompt learning algorithm to backdoor attacks. We observe that the few-shot scenarios have posed a great challenge to backdoor attacks on the prompt-based models, limiting the usability of existing NLP backdoor methods.